DE69708318D1 - Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung - Google Patents

Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung

Info

Publication number
DE69708318D1
DE69708318D1 DE69708318T DE69708318T DE69708318D1 DE 69708318 D1 DE69708318 D1 DE 69708318D1 DE 69708318 T DE69708318 T DE 69708318T DE 69708318 T DE69708318 T DE 69708318T DE 69708318 D1 DE69708318 D1 DE 69708318D1
Authority
DE
Germany
Prior art keywords
neisseria meningitidis
glycoconjugates
vaccine formulations
meningitidis serogroup
serogruppe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69708318T
Other languages
English (en)
Other versions
DE69708318T2 (de
DE69708318T3 (de
Inventor
C Seid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21820678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69708318(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69708318D1 publication Critical patent/DE69708318D1/de
Publication of DE69708318T2 publication Critical patent/DE69708318T2/de
Application granted granted Critical
Publication of DE69708318T3 publication Critical patent/DE69708318T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y10S977/917—Vaccine
DE69708318T 1996-08-27 1997-08-04 Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung Expired - Lifetime DE69708318T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2445496P 1996-08-27 1996-08-27
US24454P 1996-08-27
PCT/US1997/013609 WO1998008543A1 (en) 1996-08-27 1997-08-04 Neisseria meningitidis serogroup b glycoconjugates and methods of using the same

Publications (3)

Publication Number Publication Date
DE69708318D1 true DE69708318D1 (de) 2002-01-03
DE69708318T2 DE69708318T2 (de) 2002-07-11
DE69708318T3 DE69708318T3 (de) 2006-11-16

Family

ID=21820678

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69708318T Expired - Lifetime DE69708318T3 (de) 1996-08-27 1997-08-04 Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung

Country Status (11)

Country Link
US (2) US6638513B2 (de)
EP (1) EP0939647B2 (de)
JP (2) JP4162267B2 (de)
AT (1) ATE208629T1 (de)
CA (1) CA2264735C (de)
DE (1) DE69708318T3 (de)
DK (1) DK0939647T4 (de)
ES (1) ES2166097T5 (de)
HK (1) HK1021145A1 (de)
PT (1) PT939647E (de)
WO (1) WO1998008543A1 (de)

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WO1998008874A1 (en) 1996-08-27 1998-03-05 Chiron Corporation Monoclonal antibodies that define unique meningococcal b epitopes and their use in the preparation of vaccine compositions
EP0939647B2 (de) * 1996-08-27 2006-07-12 Chiron Corporation Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
EP0994723A1 (de) 1997-06-24 2000-04-26 Chiron Corporation Verfahren um erwachsenen mit anti-meningokokken impfstoffzusammensetzungen zu immunizieren
GB9808866D0 (en) * 1998-04-24 1998-06-24 Smithkline Beecham Biolog Novel compounds
WO1999061053A1 (en) * 1998-05-29 1999-12-02 Chiron Corporation Combination meningitidis b/c vaccines
WO2002080648A2 (en) * 2001-04-05 2002-10-17 Chiron Corporation Mucosal boosting following parenteral priming
DE60235155D1 (de) 2001-04-17 2010-03-11 Childrens Hosp Oak Res Inst Monoklonale antikörper gegen molekulare mimetika von meningokokken-b-epitopen
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
EP1490409B1 (de) * 2002-03-26 2008-12-31 Novartis Vaccines and Diagnostics S.r.l. Modifizierte saccharide mit verbesserter stabilität in wasser
CA2514328C (en) 2003-01-30 2020-01-14 Chiron Srl Injectable vaccines against multiple meningococcal serogroups
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
EP1784428A2 (de) * 2004-06-23 2007-05-16 Children's Hospital & Research Center at Oakland Polysaccharidderivate und verwendung bei der induktion einer immunantwort
GB0611914D0 (en) * 2006-06-15 2006-07-26 Teti Giuseppe Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
EP2173759A4 (de) * 2007-07-03 2014-01-29 Childrens Hosp & Res Ct Oak Oligosialinsäúrederivate, verfahren zu ihrer herstellung und ihre immunologische verwendung
JP5523313B2 (ja) 2007-07-03 2014-06-18 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
CA2793510A1 (en) * 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
HUE052850T2 (hu) 2010-08-23 2021-05-28 Wyeth Llc Neisseria meningitidis RLP2086 antigéneket tartalmazó stabil készítmények
NZ607224A (en) 2010-09-10 2014-11-28 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
SG10201806648TA (en) 2011-07-01 2018-09-27 Ngm Biopharmaceuticals Inc Compositions, uses and methods for treatment of metabolic disorders and diseases
KR101763625B1 (ko) 2012-03-09 2017-08-01 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
JP6578206B2 (ja) 2012-07-19 2019-09-18 レッドウッド バイオサイエンス， インコーポレイテッド Ｃｄ２２に特異的な抗体およびその使用方法
BR112015003326A2 (pt) 2012-08-16 2017-07-04 Ipierian Inc métodos de tratamento de uma tauopatia
WO2014066744A2 (en) 2012-10-25 2014-05-01 True North Therapeutics, Inc. Anti-complement c1s antibodies and uses thereof
RS63212B1 (sr) 2012-11-02 2022-06-30 Bioverativ Usa Inc Antikomplementna c1s antitela i njihove primene
US9963494B2 (en) 2012-11-28 2018-05-08 Ngm Biopharmaceuticals, Inc. Methods of using compositions comprising variants and fusions of FGF19 polypeptides for reducing glucose levels in a subject
CA2943263C (en) 2012-12-20 2018-12-04 Pfizer Inc. Glycoconjugation process
CN105008548B (zh) 2012-12-27 2020-11-27 恩格姆生物制药公司 用于调节胆汁酸体内稳态以及治疗胆汁酸紊乱和疾病的方法
ES2685894T3 (es) 2013-03-08 2018-10-15 Pfizer Inc. Polipéptidos de fusión inmunogénicos
ES2800827T3 (es) 2013-06-10 2021-01-04 Ipierian Inc Procedimientos de tratamiento de una tauopatía
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
EP3074420A2 (de) 2013-11-27 2016-10-05 Ipierian, Inc. Verfahren zur behandlung einer tauopathie
IL251834B2 (en) 2014-10-23 2023-09-01 Ngm Biopharmaceuticals Inc Pharmaceutical compositions containing peptide variants and methods of using them
EP3270959A1 (de) 2015-02-19 2018-01-24 Pfizer Inc Neisseria meningitidis-zusammensetzungen und verfahren dafür
CA3003616C (en) 2015-11-09 2020-07-28 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders
KR20190003951A (ko) 2016-04-04 2019-01-10 바이오버라티브 유에스에이 인코포레이티드 항-보체 인자 bb 항체 및 이의 용도
SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof

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US4902506A (en) † 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
IT1187753B (it) * 1985-07-05 1987-12-23 Sclavo Spa Coniugati glicoproteici ad attivita' immunogenica trivalente
US4727136A (en) † 1985-10-01 1988-02-23 Canadian Patents And Development Ltd. Modified meningococcal group B polysaccharide for conjugate vaccine
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens
JP2637845B2 (ja) * 1989-12-14 1997-08-06 ナシヨナル・リサーチ・カウンシル・カナダ 修飾メニンゴコツクス多糖複合ワクチン
US5153312A (en) * 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
US5354853A (en) * 1993-03-12 1994-10-11 Genzyme Corporation Phospholipid-saccharide conjugates
GB9422096D0 (en) 1994-11-02 1994-12-21 Biocine Spa Combined meningitis vaccine
US5811102A (en) * 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
CZ327897A3 (cs) * 1995-06-07 1998-02-18 Alberta Research Council Imunogenní a imunostimulační oligosacharidové kompozice, způsoby jejich přípravy a použití
EP0939647B2 (de) * 1996-08-27 2006-07-12 Chiron Corporation Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
WO1998008874A1 (en) 1996-08-27 1998-03-05 Chiron Corporation Monoclonal antibodies that define unique meningococcal b epitopes and their use in the preparation of vaccine compositions
EP0994723A1 (de) * 1997-06-24 2000-04-26 Chiron Corporation Verfahren um erwachsenen mit anti-meningokokken impfstoffzusammensetzungen zu immunizieren
WO1999010372A1 (en) 1997-08-27 1999-03-04 Chiron Corporation Molecular mimetics of meningococcal b epitopes

Also Published As

Publication number Publication date
US6638513B2 (en) 2003-10-28
EP0939647B2 (de) 2006-07-12
WO1998008543A1 (en) 1998-03-05
ES2166097T3 (es) 2002-04-01
EP0939647B1 (de) 2001-11-14
JP4162267B2 (ja) 2008-10-08
US20020034518A1 (en) 2002-03-21
ES2166097T5 (es) 2007-03-16
JP2008201793A (ja) 2008-09-04
ATE208629T1 (de) 2001-11-15
US7169392B2 (en) 2007-01-30
CA2264735C (en) 2008-01-29
EP0939647A1 (de) 1999-09-08
DK0939647T3 (da) 2002-04-02
PT939647E (pt) 2002-04-29
CA2264735A1 (en) 1998-03-05
DE69708318T2 (de) 2002-07-11
JP2001500540A (ja) 2001-01-16
DK0939647T4 (da) 2006-10-23
HK1021145A1 (en) 2000-06-02
DE69708318T3 (de) 2006-11-16
US20040052805A1 (en) 2004-03-18

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC., EMERYVILL