ATE325803T1 - Glycokonjugate, glycoaminosäure, deren zwischenprodukte, und ihre verwendung - Google Patents

Glycokonjugate, glycoaminosäure, deren zwischenprodukte, und ihre verwendung

Info

Publication number
ATE325803T1
ATE325803T1 AT00957619T AT00957619T ATE325803T1 AT E325803 T1 ATE325803 T1 AT E325803T1 AT 00957619 T AT00957619 T AT 00957619T AT 00957619 T AT00957619 T AT 00957619T AT E325803 T1 ATE325803 T1 AT E325803T1
Authority
AT
Austria
Prior art keywords
glycoconjugates
methods
present
intermediate products
glycoamino acids
Prior art date
Application number
AT00957619T
Other languages
English (en)
Inventor
Samuel J Danishefsky
Jennifer R Allen
Govindaswami Ragupathi
Philip O Livingston
Lawrence Williams
Original Assignee
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Inst Cancer filed Critical Sloan Kettering Inst Cancer
Application granted granted Critical
Publication of ATE325803T1 publication Critical patent/ATE325803T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT00957619T 1999-08-20 2000-08-18 Glycokonjugate, glycoaminosäure, deren zwischenprodukte, und ihre verwendung ATE325803T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15008899P 1999-08-20 1999-08-20

Publications (1)

Publication Number Publication Date
ATE325803T1 true ATE325803T1 (de) 2006-06-15

Family

ID=22533089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00957619T ATE325803T1 (de) 1999-08-20 2000-08-18 Glycokonjugate, glycoaminosäure, deren zwischenprodukte, und ihre verwendung

Country Status (9)

Country Link
US (3) US7879335B1 (de)
EP (1) EP1210355B1 (de)
JP (2) JP5111705B2 (de)
AT (1) ATE325803T1 (de)
AU (1) AU6921300A (de)
DE (1) DE60027905T2 (de)
ES (1) ES2267559T3 (de)
HK (1) HK1048819B (de)
WO (1) WO2001014395A2 (de)

Families Citing this family (15)

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WO1998046246A1 (en) 1997-04-16 1998-10-22 Sloan-Kettering Institute For Cancer Research α-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF
US7854934B2 (en) * 1999-08-20 2010-12-21 Sloan-Kettering Institute For Cancer Research Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
US7824687B2 (en) 1999-08-20 2010-11-02 Sloan-Kettering Institute For Cancer Research Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
ES2267559T3 (es) 1999-08-20 2007-03-16 Sloan-Kettering Institute For Cancer Research Glicoconjugados, glicoamino, acidos sus intermediarios y el uso de los mismos.
GB0314741D0 (en) * 2003-06-24 2003-07-30 Isis Innovation Reagents and methods
HRP20120701T1 (hr) 2005-12-08 2012-10-31 Medarex, Inc. Humana monoklonska protutijela protiv fukozil-gm1 i postupci za uporabu antifukozil-gm1
JP2009541259A (ja) * 2006-06-20 2009-11-26 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 糖抗原に対する特異抗体の製造方法
KR100849979B1 (ko) 2006-12-06 2008-08-01 주식회사 삼천리제약 2-데옥시-엘-리보오스의 제조방법
EP1953237A1 (de) * 2007-02-01 2008-08-06 Ecover N.V. Verfahren zur Herstellung von kurzkettigen Glycolipiden
CA2681766A1 (en) * 2007-03-23 2008-10-02 The Governors Of The University Of Alberta Multivalent heterobifunctional polymers and methods of their use
AU2009268349C1 (en) * 2008-07-11 2015-01-22 Sloan-Kettering Institute For Cancer Research Glycopeptide constructs and uses thereof
NZ604089A (en) 2010-06-11 2015-03-27 Sloan Kettering Inst Cancer Multivalent glycopeptide constructs and uses thereof
JP6218085B2 (ja) * 2015-05-18 2017-10-25 国立大学法人信州大学 修飾キシロポリサッカライドの製造方法
TW202110482A (zh) * 2019-05-24 2021-03-16 日商糖鎖工學研究所股份有限公司 新穎的人工蛋白質觸媒

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US4971795A (en) 1986-07-08 1990-11-20 Biomira, Inc. Enhancement of the cellular immune response using carbohydrate primed DTH effector cells expressing the CD5+/CD8- phenotype
JPH02501828A (ja) 1987-01-07 1990-06-21 インペリアル・キヤンサー・リサーチ・テクノロジー・リミテツド プローブ
US5683674A (en) 1987-01-07 1997-11-04 Imperial Cancer Research Technology Ltd. Antibody against human mucin core protein and method of preparing and using same
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Also Published As

Publication number Publication date
WO2001014395A3 (en) 2001-09-07
HK1048819B (en) 2006-11-10
HK1048819A1 (en) 2003-04-17
AU6921300A (en) 2001-03-19
EP1210355A2 (de) 2002-06-05
US8623378B2 (en) 2014-01-07
JP2012132025A (ja) 2012-07-12
US9464116B2 (en) 2016-10-11
US20140271817A1 (en) 2014-09-18
DE60027905D1 (de) 2006-06-14
WO2001014395A2 (en) 2001-03-01
US20110206757A1 (en) 2011-08-25
ES2267559T3 (es) 2007-03-16
JP2003507485A (ja) 2003-02-25
EP1210355B1 (de) 2006-05-10
DE60027905T2 (de) 2007-05-10
JP5111705B2 (ja) 2013-01-09
US7879335B1 (en) 2011-02-01

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