JP2019513126A5 - - Google Patents
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- Publication number
- JP2019513126A5 JP2019513126A5 JP2018545900A JP2018545900A JP2019513126A5 JP 2019513126 A5 JP2019513126 A5 JP 2019513126A5 JP 2018545900 A JP2018545900 A JP 2018545900A JP 2018545900 A JP2018545900 A JP 2018545900A JP 2019513126 A5 JP2019513126 A5 JP 2019513126A5
- Authority
- JP
- Japan
- Prior art keywords
- ethoxy
- amino
- xaa
- acetyl
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(c(cc1)ccc1OCCCCCCCC=O)=O Chemical compound *C(c(cc1)ccc1OCCCCCCCC=O)=O 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16158388 | 2016-03-03 | ||
| EP16158388.5 | 2016-03-03 | ||
| PCT/EP2017/054895 WO2017149070A1 (en) | 2016-03-03 | 2017-03-02 | Glp-1 derivatives and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019513126A JP2019513126A (ja) | 2019-05-23 |
| JP2019513126A5 true JP2019513126A5 (enExample) | 2020-04-09 |
| JP7053480B2 JP7053480B2 (ja) | 2022-04-12 |
Family
ID=55451126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545900A Active JP7053480B2 (ja) | 2016-03-03 | 2017-03-02 | Ｇｌｐ－１誘導体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10946074B2 (enExample) |
| EP (1) | EP3423481B1 (enExample) |
| JP (1) | JP7053480B2 (enExample) |
| CN (1) | CN108699126B (enExample) |
| ES (1) | ES2835033T3 (enExample) |
| WO (1) | WO2017149070A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI847306B (zh) | 2017-08-24 | 2024-07-01 | 丹麥商諾佛 儂迪克股份有限公司 | Ｇｌｐ-１組成物及其用途 |
| ES2980707T3 (es) | 2018-04-05 | 2024-10-02 | Sun Pharmaceutical Ind Ltd | Nuevos análogos de GLP-1 |
| CN115814063A (zh) * | 2018-04-19 | 2023-03-21 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| WO2020104833A1 (en) | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN109730270B (zh) * | 2019-02-12 | 2022-06-28 | 西安培华学院 | 一种降糖酵母发酵南瓜粉及制备方法和应用 |
| BR112022013795A2 (pt) | 2020-02-18 | 2022-09-13 | Novo Nordisk As | Composição farmacêutica líquida, e, kit |
| AU2021278157A1 (en) * | 2020-05-29 | 2022-11-24 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Dual-agonist compound for both GLP-1 and GIP receptors and application thereof |
| JP2023545684A (ja) | 2020-09-30 | 2023-10-31 | ベイジン キューエル バイオファーマシューティカル カンパニー，リミテッド | ポリペプチドコンジュゲートおよび使用の方法 |
| EP4281464A4 (en) | 2021-01-20 | 2025-01-01 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| JP7642830B2 (ja) | 2021-09-15 | 2025-03-10 | バイキング・セラピューティクス・インコーポレイテッド | 代謝及び肝臓障害の処置のための組成物及び方法 |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
| WO2026008836A1 (en) | 2024-07-05 | 2026-01-08 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| WO2026019692A2 (en) * | 2024-07-15 | 2026-01-22 | Flagship Pioneering Innovations Vii, Llc | Immunomodulatory fusion proteins and related methods |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| WO2000050012A1 (en) | 1999-02-22 | 2000-08-31 | Elan Corporation, Plc | Solid oral dosage form containing an enhancer |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| EP2164466A1 (en) | 2007-06-01 | 2010-03-24 | Novo Nordisk A/S | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier |
| ES2672770T3 (es) | 2007-09-05 | 2018-06-18 | Novo Nordisk A/S | Derivados del péptido-1 similar al glucagón y su uso farmacéutico |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| CN101255191A (zh) | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| JP2012518029A (ja) | 2009-02-19 | 2012-08-09 | ノヴォ・ノルディスク・アー／エス | 第ｖｉｉｉ因子の修飾 |
| CN104327182B (zh) | 2009-12-16 | 2020-04-17 | 诺沃—诺迪斯克有限公司 | 双酰化glp-1衍生物 |
| MX345501B (es) | 2010-12-16 | 2017-02-02 | Novo Nordisk As | Composiciones solidas que comprenden agonista de glp-1 y sal del acido n-(8-(2-hidroxibenzoil)amino)caprilico. |
| KR101972836B1 (ko) | 2011-04-12 | 2019-04-29 | 노보 노르디스크 에이/에스 | 이중 아실화된 ｇｌｐ-1 유도체 |
| CN102180963B (zh) | 2011-04-22 | 2014-06-25 | 中国药科大学 | 胰高血糖素样肽-1(glp-1)类似物及其应用 |
| AU2012360998B2 (en) | 2011-12-29 | 2017-11-23 | Novo Nordisk A/S | Dipeptide comprising a non-proteogenic amino acid |
| EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
| CN103087178A (zh) | 2012-11-30 | 2013-05-08 | 中国药科大学 | 长效化胰高血糖素样肽-1(glp-1)类似物及其应用 |
| EP3010546B1 (en) | 2013-06-20 | 2017-08-09 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| BR112015032875A2 (pt) | 2013-07-04 | 2017-11-07 | Novo Nordisk As | derivados de peptídeos do tipo glp-1, e usos dos mesmos |
| US10077319B2 (en) | 2014-02-21 | 2018-09-18 | Medimmune, Llc | Anti-PCSK9-GLP-1 fusions and methods for use |
| ES2741507T3 (es) | 2014-04-07 | 2020-02-11 | Novo Nordisk As | Compuestos de glp-1 acilados doblemente |
| JP6730278B2 (ja) | 2014-11-27 | 2020-07-29 | ノヴォ ノルディスク アー／エス | Ｇｌｐ−１誘導体及びその使用 |
| US10392428B2 (en) | 2014-12-17 | 2019-08-27 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
-
2017
- 2017-03-02 ES ES17708491T patent/ES2835033T3/es active Active
- 2017-03-02 JP JP2018545900A patent/JP7053480B2/ja active Active
- 2017-03-02 WO PCT/EP2017/054895 patent/WO2017149070A1/en not_active Ceased
- 2017-03-02 CN CN201780014939.5A patent/CN108699126B/zh active Active
- 2017-03-02 EP EP17708491.0A patent/EP3423481B1/en active Active
- 2017-03-02 US US16/077,759 patent/US10946074B2/en active Active
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