JP2017105819A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017105819A5 JP2017105819A5 JP2017022249A JP2017022249A JP2017105819A5 JP 2017105819 A5 JP2017105819 A5 JP 2017105819A5 JP 2017022249 A JP2017022249 A JP 2017022249A JP 2017022249 A JP2017022249 A JP 2017022249A JP 2017105819 A5 JP2017105819 A5 JP 2017105819A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- lys
- gly
- glu
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175094 | 2013-07-04 | ||
| EP13175094.5 | 2013-07-04 | ||
| US201361845646P | 2013-07-12 | 2013-07-12 | |
| US61/845,646 | 2013-07-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Division JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017105819A JP2017105819A (ja) | 2017-06-15 |
| JP2017105819A5 true JP2017105819A5 (enExample) | 2017-08-24 |
| JP6687557B2 JP6687557B2 (ja) | 2020-04-22 |
Family
ID=48703344
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Active JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
| JP2017022249A Active JP6687557B2 (ja) | 2013-07-04 | 2017-02-09 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015563070A Active JP6139712B2 (ja) | 2013-07-04 | 2014-07-02 | Ｇｌｐ−１様ペプチドの誘導体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9498534B2 (enExample) |
| EP (1) | EP3016975B1 (enExample) |
| JP (2) | JP6139712B2 (enExample) |
| KR (1) | KR20160029079A (enExample) |
| CN (1) | CN105377884B (enExample) |
| AR (1) | AR096789A1 (enExample) |
| AU (1) | AU2014286234A1 (enExample) |
| BR (1) | BR112015032875A2 (enExample) |
| CA (1) | CA2916311A1 (enExample) |
| MX (1) | MX2015016875A (enExample) |
| WO (1) | WO2015000942A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014283221A1 (en) | 2013-06-20 | 2015-12-03 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
| US9498534B2 (en) * | 2013-07-04 | 2016-11-22 | Novo Nordisk A/S | Derivatives of GLP-1 like peptides, and uses thereof |
| US11572398B2 (en) | 2014-11-27 | 2023-02-07 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
| CN107108714B (zh) | 2014-12-17 | 2022-02-08 | 诺和诺德股份有限公司 | Glp-1衍生物及其用途 |
| US10118904B2 (en) | 2015-06-05 | 2018-11-06 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of Demyelinating Diseases |
| WO2017112889A1 (en) | 2015-12-23 | 2017-06-29 | The Johns Hopkins University | Long-acting glp-1r agonist as a therapy of neurological and neurodegenerative conditions |
| EP3423481B1 (en) | 2016-03-03 | 2020-10-07 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| WO2018083335A1 (en) | 2016-11-07 | 2018-05-11 | Novo Nordisk A/S | Dchbs-active esters of peg compounds and their use |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| CN108976147B (zh) * | 2017-05-31 | 2021-02-12 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
| CN109248323B (zh) * | 2017-07-14 | 2023-09-08 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| BR112020001286A2 (pt) | 2017-07-19 | 2020-07-28 | Novo Nordisk A/S | composto, e, método de tratamento da diabetes, sobrepeso e/ou doenças cardiovasculares |
| HRP20240485T1 (hr) | 2017-08-24 | 2024-07-05 | Novo Nordisk A/S | Pripravci glp-1 i njihova upotreba |
| US11339111B2 (en) * | 2017-11-30 | 2022-05-24 | Societe Des Produits Nestle S.A. | Polyketide compound and derivatives thereof for use in the prevention and treatment of a neurological disorder |
| LT3774862T (lt) | 2018-04-05 | 2022-09-12 | Sun Pharmaceutical Industries Limited | Nauji glp-1 analogai |
| WO2019200594A1 (zh) | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| CN115814063A (zh) * | 2018-04-19 | 2023-03-21 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| CN113024659B (zh) * | 2018-04-19 | 2023-07-14 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| WO2020012604A1 (ja) * | 2018-07-12 | 2020-01-16 | 三菱電機株式会社 | 半導体装置 |
| CN115260313B (zh) | 2019-12-31 | 2023-07-18 | 北京质肽生物医药科技有限公司 | Glp-1和gdf15的融合蛋白以及其缀合物 |
| WO2021139744A1 (en) | 2020-01-11 | 2021-07-15 | Beijing Ql Biopharmaceutical Co., Ltd. | Conjugates of fusion proteins of glp-1 and fgf21 |
| US20230093542A1 (en) * | 2020-02-18 | 2023-03-23 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| CN114729060B (zh) | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| CN114685644A (zh) * | 2020-12-29 | 2022-07-01 | 苏州康宁杰瑞生物科技有限公司 | 一种人glp-1多肽变体及其应用 |
| EP4288461A4 (en) | 2021-07-14 | 2025-07-02 | Beijing Ql Biopharmaceutical Co Ltd | FUSION POLYPEPTIDES FOR METABOLIC DISORDERS |
| CN116848243B (zh) | 2022-03-30 | 2024-03-19 | 北京质肽生物医药科技有限公司 | 多肽缀合物的液体药物组合物和其使用方法 |
| CN121001710A (zh) | 2022-12-30 | 2025-11-21 | 阿尔吉法玛公司 | 提高口服多肽治疗剂的全身生物利用度的组合物和方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458924B2 (en) * | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| WO1999043706A1 (en) * | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Derivatives of glp-1 analogs |
| BR0009040A (pt) | 1999-03-17 | 2001-12-18 | Novo Nordisk As | Método para acilar um grupo amino de um peptìdeoou de uma proteìna, e, composto |
| EP1076066A1 (en) * | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| WO2001035988A1 (en) * | 1999-11-12 | 2001-05-25 | Novo Nordisk A/S | Use of glp-1 agonists for the inhibition of beta cell degeneration |
| GB0020551D0 (en) | 2000-08-22 | 2000-10-11 | Birkett David | Sprinkler system |
| AU2004231461B2 (en) | 2003-03-19 | 2009-11-12 | Eli Lilly And Company | Polyethelene glycol linked GLP-1 compounds |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| BRPI0609676A2 (pt) | 2005-05-13 | 2011-10-18 | Lilly Co Eli | composto de glp-1 peguilado,e, uso do mesmo |
| JP2011504871A (ja) | 2007-06-01 | 2011-02-17 | ノボ・ノルデイスク・エー／エス | 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト |
| ES2672770T3 (es) | 2007-09-05 | 2018-06-18 | Novo Nordisk A/S | Derivados del péptido-1 similar al glucagón y su uso farmacéutico |
| JP5606314B2 (ja) | 2007-09-05 | 2014-10-15 | ノボ・ノルデイスク・エー／エス | Ａ−ｂ−ｃ−ｄ−で誘導体化されたペプチドとその治療用途 |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| CN102333788A (zh) | 2009-02-19 | 2012-01-25 | 诺沃—诺迪斯克有限公司 | 因子viii的修饰 |
| JP5411366B2 (ja) * | 2009-12-16 | 2014-02-12 | ノヴォ ノルディスク アー／エス | 二重アシル化ｇｌｐ−１誘導体 |
| EP2637698B1 (en) | 2010-11-09 | 2022-04-20 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
| HUE031405T2 (en) * | 2011-04-12 | 2017-07-28 | Novo Nordisk As | Double-acylated GLP-1 derivatives |
| US9498534B2 (en) * | 2013-07-04 | 2016-11-22 | Novo Nordisk A/S | Derivatives of GLP-1 like peptides, and uses thereof |
-
2014
- 2014-07-02 US US14/322,077 patent/US9498534B2/en active Active
- 2014-07-02 AU AU2014286234A patent/AU2014286234A1/en not_active Abandoned
- 2014-07-02 CN CN201480038380.6A patent/CN105377884B/zh active Active
- 2014-07-02 KR KR1020167002151A patent/KR20160029079A/ko not_active Withdrawn
- 2014-07-02 BR BR112015032875A patent/BR112015032875A2/pt not_active Application Discontinuation
- 2014-07-02 MX MX2015016875A patent/MX2015016875A/es unknown
- 2014-07-02 JP JP2015563070A patent/JP6139712B2/ja active Active
- 2014-07-02 EP EP14734816.3A patent/EP3016975B1/en active Active
- 2014-07-02 AR ARP140102467A patent/AR096789A1/es unknown
- 2014-07-02 CA CA2916311A patent/CA2916311A1/en not_active Withdrawn
- 2014-07-02 WO PCT/EP2014/064033 patent/WO2015000942A1/en not_active Ceased
-
2016
- 2016-09-28 US US15/278,501 patent/US10010614B2/en active Active
-
2017
- 2017-02-09 JP JP2017022249A patent/JP6687557B2/ja active Active