JP2018506507A5 - - Google Patents
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- JP2018506507A5 JP2018506507A5 JP2017528491A JP2017528491A JP2018506507A5 JP 2018506507 A5 JP2018506507 A5 JP 2018506507A5 JP 2017528491 A JP2017528491 A JP 2017528491A JP 2017528491 A JP2017528491 A JP 2017528491A JP 2018506507 A5 JP2018506507 A5 JP 2018506507A5
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- xaa
- chem
- prevention
- treatment
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14195172 | 2014-11-27 | ||
| EP14195172.3 | 2014-11-27 | ||
| PCT/EP2015/077757 WO2016083499A1 (en) | 2014-11-27 | 2015-11-26 | Glp-1 derivatives and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018506507A JP2018506507A (ja) | 2018-03-08 |
| JP2018506507A5 true JP2018506507A5 (enExample) | 2019-01-10 |
| JP6730278B2 JP6730278B2 (ja) | 2020-07-29 |
Family
ID=51982467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017528491A Active JP6730278B2 (ja) | 2014-11-27 | 2015-11-26 | Ｇｌｐ−１誘導体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11572398B2 (enExample) |
| EP (1) | EP3226906B1 (enExample) |
| JP (1) | JP6730278B2 (enExample) |
| CN (1) | CN106999602B (enExample) |
| ES (1) | ES2739289T3 (enExample) |
| WO (1) | WO2016083499A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3010546B1 (en) | 2013-06-20 | 2017-08-09 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| US10392428B2 (en) | 2014-12-17 | 2019-08-27 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
| PL3393496T3 (pl) | 2015-12-23 | 2024-04-22 | The Johns Hopkins University | Długo działający agonista glp-1r jako terapia stanów neurologicznych i neurodegeneracyjnych |
| ES2835033T3 (es) | 2016-03-03 | 2021-06-21 | Novo Nordisk As | Derivados de GLP-1 y sus usos |
| MA46780A (fr) | 2016-11-07 | 2019-09-11 | Novo Nordisk As | Esters à dchbs actif de composés peg et leur utilisation |
| WO2018113340A1 (zh) * | 2016-12-20 | 2018-06-28 | 中国药科大学 | 多肽p11及其用途 |
| CN109248323B (zh) * | 2017-07-14 | 2023-09-08 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| TWI847306B (zh) * | 2017-08-24 | 2024-07-01 | 丹麥商諾佛 儂迪克股份有限公司 | Ｇｌｐ-１組成物及其用途 |
| ES2980707T3 (es) | 2018-04-05 | 2024-10-02 | Sun Pharmaceutical Ind Ltd | Nuevos análogos de GLP-1 |
| WO2019200594A1 (zh) * | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| WO2019201333A1 (zh) * | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| TWI707865B (zh) * | 2018-05-04 | 2020-10-21 | 丹麥商諾佛 儂迪克股份有限公司 | Gip衍生物及其用途 |
| JP7422754B2 (ja) * | 2018-10-26 | 2024-01-26 | ノヴォ ノルディスク アー／エス | 安定性セマグルチド組成物およびその使用 |
| CN115322794B (zh) | 2020-01-11 | 2025-09-19 | 北京质肽生物医药科技有限公司 | Glp-1和fgf21的融合蛋白的缀合物 |
| JP2023545684A (ja) | 2020-09-30 | 2023-10-31 | ベイジン キューエル バイオファーマシューティカル カンパニー，リミテッド | ポリペプチドコンジュゲートおよび使用の方法 |
| IL303578A (en) | 2020-12-16 | 2023-08-01 | Medimmune Ltd | Polypeptides and their uses |
| TW202440619A (zh) | 2020-12-18 | 2024-10-16 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1及澱粉素受體之共促效劑 |
| TW202304500A (zh) * | 2021-04-21 | 2023-02-01 | 瑞士商諾華公司 | 升糖素樣肽化合物 |
| CA3224743A1 (en) | 2021-07-14 | 2023-01-19 | Beijing Ql Biopharmaceutical Co., Ltd. | Fusion polypeptides for metabolic disorders |
| CN114621339B (zh) * | 2021-12-28 | 2022-09-23 | 北京惠之衡生物科技有限公司 | 一种长效glp-1衍生物 |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| CN117586375B (zh) * | 2024-01-19 | 2024-07-30 | 苏州金顶生物有限公司 | 一种制备司美格鲁肽的方法 |
| CN120081924A (zh) * | 2024-07-11 | 2025-06-03 | 中国药科大学 | Glp-1r受体激动多肽化合物及其用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| WO1999043706A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Derivatives of glp-1 analogs |
| PL351326A1 (en) | 1999-03-17 | 2003-04-07 | Novo Nordisk As | Method for acylating peptides and novel acylating agents |
| EP1239871A1 (en) | 1999-11-12 | 2002-09-18 | Novo Nordisk A/S | Use of glp-1 agonists for the inhibition of beta cell degeneration |
| GB0020551D0 (en) | 2000-08-22 | 2000-10-11 | Birkett David | Sprinkler system |
| MXPA04006679A (es) | 2002-01-08 | 2004-11-10 | Lilly Co Eli | Analogos extendidos de peptido-1 de tipo glucagon. |
| EA009366B1 (ru) | 2003-03-19 | 2007-12-28 | Эли Лилли Энд Компани | Связанные с полиэтиленгликолем соединения гпп-1 |
| TWI353991B (en) * | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| CA2539253A1 (en) * | 2003-09-19 | 2005-03-31 | Novo Nordisk A/S | Albumin-binding derivatives of therapeutic peptides |
| CN101380476A (zh) * | 2003-09-19 | 2009-03-11 | 诺沃挪第克公司 | 治疗肽的清蛋白结合型衍生物 |
| WO2006037810A2 (en) | 2004-10-07 | 2006-04-13 | Novo Nordisk A/S | Protracted glp-1 compounds |
| TWI372629B (en) * | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| BRPI0608516A2 (pt) | 2005-03-18 | 2010-11-16 | Novo Nordisk As | análogo de glp-1, método para aumentar o tempo de ação em um paciente de um análogo de glp-1, composição farmacêutica, e, uso de um composto |
| KR101011081B1 (ko) | 2005-05-13 | 2011-01-25 | 일라이 릴리 앤드 캄파니 | Ｐｅｇ화된 ｇｌｐ-1 화합물 |
| US20100261637A1 (en) | 2007-09-05 | 2010-10-14 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| ES2672770T3 (es) * | 2007-09-05 | 2018-06-18 | Novo Nordisk A/S | Derivados del péptido-1 similar al glucagón y su uso farmacéutico |
| US20120172298A1 (en) | 2009-06-11 | 2012-07-05 | Novo Nordisk A/S | Glp-1 and fgf21 combinations for treatment of diabetes type 2 |
| CN104327182B (zh) | 2009-12-16 | 2020-04-17 | 诺沃—诺迪斯克有限公司 | 双酰化glp-1衍生物 |
| US20130143798A1 (en) | 2010-03-26 | 2013-06-06 | Novo Nordisk A/S | Novel glucagon analogues |
| WO2012012352A2 (en) | 2010-07-19 | 2012-01-26 | Amidebio, Llc | Modified peptides and proteins |
| CN105601729A (zh) | 2010-11-09 | 2016-05-25 | 诺沃—诺迪斯克有限公司 | 双-酰化的glp-1衍生物 |
| CA2821766A1 (en) * | 2010-12-22 | 2012-06-28 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting gip receptor activity |
| KR101972836B1 (ko) * | 2011-04-12 | 2019-04-29 | 노보 노르디스크 에이/에스 | 이중 아실화된 ｇｌｐ-1 유도체 |
| CN103906528A (zh) | 2011-06-24 | 2014-07-02 | 安米林药品有限责任公司 | 用glp-1受体激动剂的缓释制剂治疗糖尿病的方法 |
| JP6352806B2 (ja) | 2011-09-23 | 2018-07-04 | ノヴォ ノルディスク アー／エス | 新規のグルカゴン類似体 |
| JP6250034B2 (ja) | 2012-05-08 | 2017-12-20 | ノヴォ ノルディスク アー／エス | 二重アシル化されたｇｌｐ−１誘導体 |
| EP3010546B1 (en) | 2013-06-20 | 2017-08-09 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| BR112015032875A2 (pt) | 2013-07-04 | 2017-11-07 | Novo Nordisk As | derivados de peptídeos do tipo glp-1, e usos dos mesmos |
| US10392428B2 (en) | 2014-12-17 | 2019-08-27 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
-
2015
- 2015-11-26 JP JP2017528491A patent/JP6730278B2/ja active Active
- 2015-11-26 CN CN201580063041.8A patent/CN106999602B/zh active Active
- 2015-11-26 WO PCT/EP2015/077757 patent/WO2016083499A1/en not_active Ceased
- 2015-11-26 ES ES15801781T patent/ES2739289T3/es active Active
- 2015-11-26 US US15/531,105 patent/US11572398B2/en active Active
- 2015-11-26 EP EP15801781.4A patent/EP3226906B1/en active Active
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