JP7053480B2 - Glp-1誘導体及びその使用 - Google Patents
Glp-1誘導体及びその使用 Download PDFInfo
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- JP7053480B2 JP7053480B2 JP2018545900A JP2018545900A JP7053480B2 JP 7053480 B2 JP7053480 B2 JP 7053480B2 JP 2018545900 A JP2018545900 A JP 2018545900A JP 2018545900 A JP2018545900 A JP 2018545900A JP 7053480 B2 JP7053480 B2 JP 7053480B2
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
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| PCT/EP2017/054895 WO2017149070A1 (en) | 2016-03-03 | 2017-03-02 | Glp-1 derivatives and uses thereof |
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| EP3474820B1 (en) | 2017-08-24 | 2024-02-07 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| PE20211417A1 (es) | 2018-04-05 | 2021-08-02 | Sun Pharmaceutical Ind Ltd | Analogos novedosos de glp-1 |
| CN115814064A (zh) * | 2018-04-19 | 2023-03-21 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| WO2020104833A1 (en) | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN109730270B (zh) * | 2019-02-12 | 2022-06-28 | 西安培华学院 | 一种降糖酵母发酵南瓜粉及制备方法和应用 |
| PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
| TW202144393A (zh) * | 2020-05-29 | 2021-12-01 | 大陸商北京拓界生物醫藥科技有限公司 | Glp-1和gip受體雙重激動劑化合物及其應用 |
| JP2023545684A (ja) | 2020-09-30 | 2023-10-31 | ベイジン キューエル バイオファーマシューティカル カンパニー,リミテッド | ポリペプチドコンジュゲートおよび使用の方法 |
| CA3204051A1 (en) | 2021-01-20 | 2022-07-28 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| WO2023044290A1 (en) | 2021-09-15 | 2023-03-23 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| CA3252113A1 (en) | 2022-03-30 | 2023-10-05 | Beijing Ql Biopharmaceutical Co Ltd | Liquid pharmaceutical compositions of polypeptide conjugates and their methods of use |
| CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
Citations (3)
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| CN101255191A (zh) | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| JP2014511870A (ja) | 2011-04-12 | 2014-05-19 | ノヴォ ノルディスク アー/エス | 二重アシル化されたglp−1誘導体 |
| JP2016523243A (ja) | 2013-06-20 | 2016-08-08 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
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| ES2283025T3 (es) | 1996-08-30 | 2007-10-16 | Novo Nordisk A/S | Derivados de glp-1.1. |
| DE60038097T2 (de) | 1999-02-22 | 2009-02-12 | Merrion Research I Ltd. | Feste orale dosierungsform enthaltend einen resorptionsverstärker |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| EP2514406A1 (en) | 2007-06-01 | 2012-10-24 | Novo Nordisk A/S | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier |
| WO2009030738A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| CN102333788A (zh) | 2009-02-19 | 2012-01-25 | 诺沃—诺迪斯克有限公司 | 因子viii的修饰 |
| JP6006118B2 (ja) | 2009-12-16 | 2016-10-12 | ノヴォ ノルディスク アー/エス | Glp−1アナログ及び誘導体 |
| RU2600440C3 (ru) | 2010-12-16 | 2021-12-10 | Ново Нордиск А/С | Твердые композиции, содержащие агонист glp-1 и соль n-(8-(2-гидроксибензоил)амино)каприловой кислоты |
| CN102180963B (zh) | 2011-04-22 | 2014-06-25 | 中国药科大学 | 胰高血糖素样肽-1(glp-1)类似物及其应用 |
| KR101922164B1 (ko) | 2011-12-29 | 2019-02-13 | 노보 노르디스크 에이/에스 | 비-단백질원 아미노산을 포함하는 디펩티드 |
| US10933120B2 (en) | 2012-03-22 | 2021-03-02 | Novo Nordisk A/S | Compositions of GLP-1 peptides and preparation thereof |
| CN103087178A (zh) | 2012-11-30 | 2013-05-08 | 中国药科大学 | 长效化胰高血糖素样肽-1(glp-1)类似物及其应用 |
| US9498534B2 (en) | 2013-07-04 | 2016-11-22 | Novo Nordisk A/S | Derivatives of GLP-1 like peptides, and uses thereof |
| WO2015127273A1 (en) | 2014-02-21 | 2015-08-27 | Medimmune, Llc | Anti-pcsk9~glp-1 fusions and methods for use |
| CN106132985B (zh) | 2014-04-07 | 2020-10-13 | 诺和诺德股份有限公司 | 双酰化glp-1化合物 |
| CN106999602B (zh) | 2014-11-27 | 2022-02-01 | 诺和诺德股份有限公司 | Glp-1衍生物及其用途 |
| JP6691125B2 (ja) | 2014-12-17 | 2020-04-28 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
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| CN101255191A (zh) | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| JP2014511870A (ja) | 2011-04-12 | 2014-05-19 | ノヴォ ノルディスク アー/エス | 二重アシル化されたglp−1誘導体 |
| JP2016523243A (ja) | 2013-06-20 | 2016-08-08 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
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Also Published As
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| JP2019513126A (ja) | 2019-05-23 |
| EP3423481B1 (en) | 2020-10-07 |
| EP3423481A1 (en) | 2019-01-09 |
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| US20190038721A1 (en) | 2019-02-07 |
| US10946074B2 (en) | 2021-03-16 |
| WO2017149070A1 (en) | 2017-09-08 |
| CN108699126B (zh) | 2022-12-06 |
| CN108699126A (zh) | 2018-10-23 |
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