CN108699126B - Glp-1衍生物及其用途 - Google Patents
Glp-1衍生物及其用途 Download PDFInfo
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- CN108699126B CN108699126B CN201780014939.5A CN201780014939A CN108699126B CN 108699126 B CN108699126 B CN 108699126B CN 201780014939 A CN201780014939 A CN 201780014939A CN 108699126 B CN108699126 B CN 108699126B
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16158388 | 2016-03-03 | ||
| EP16158388.5 | 2016-03-03 | ||
| PCT/EP2017/054895 WO2017149070A1 (en) | 2016-03-03 | 2017-03-02 | Glp-1 derivatives and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108699126A CN108699126A (zh) | 2018-10-23 |
| CN108699126B true CN108699126B (zh) | 2022-12-06 |
Family
ID=55451126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780014939.5A Active CN108699126B (zh) | 2016-03-03 | 2017-03-02 | Glp-1衍生物及其用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10946074B2 (enExample) |
| EP (1) | EP3423481B1 (enExample) |
| JP (1) | JP7053480B2 (enExample) |
| CN (1) | CN108699126B (enExample) |
| ES (1) | ES2835033T3 (enExample) |
| WO (1) | WO2017149070A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6633777B2 (ja) | 2017-08-24 | 2020-01-22 | ノヴォ ノルディスク アー/エス | Glp−1組成物及びその使用 |
| DK3774862T3 (da) | 2018-04-05 | 2022-09-05 | Sun Pharmaceutical Ind Ltd | Nye GLP-1-analoger |
| CN115814064A (zh) * | 2018-04-19 | 2023-03-21 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| WO2020104833A1 (en) | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN109730270B (zh) * | 2019-02-12 | 2022-06-28 | 西安培华学院 | 一种降糖酵母发酵南瓜粉及制备方法和应用 |
| AU2021208601B2 (en) | 2020-02-18 | 2025-06-05 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| KR20230018395A (ko) * | 2020-05-29 | 2023-02-07 | 베이징 투오 지에 바이오파마수티컬 컴퍼니 리미티드 | Glp-1 및 gip 수용체 둘 모두에 대한 이중 작용제 화합물 및 이의 적용 |
| KR20230083294A (ko) | 2020-09-30 | 2023-06-09 | 베이징 큐엘 바이오파마슈티컬 컴퍼니 리미티드 | 폴리펩타이드 접합체 및 사용 방법 |
| KR20240118914A (ko) | 2021-01-20 | 2024-08-05 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 질환 치료를 위한 조성물 및 방법 |
| WO2023044290A1 (en) | 2021-09-15 | 2023-03-23 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| CA3252113A1 (en) | 2022-03-30 | 2023-10-05 | Beijing Ql Biopharmaceutical Co., Ltd. | Liquid pharmaceutical compositions of polypeptide conjugates and their methods of use |
| CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101255191A (zh) * | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| WO2012140117A1 (en) * | 2011-04-12 | 2012-10-18 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
| WO2014202727A1 (en) * | 2013-06-20 | 2014-12-24 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP3149958B2 (ja) | 1996-08-30 | 2001-03-26 | ノボ ノルディスク アクティーゼルスカブ | Glp―1誘導体 |
| ES2301477T3 (es) | 1999-02-22 | 2008-07-01 | Merrion Research I Limited | Forma de dosificacion oral solida que contiene un potenciador. |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| JP2011504871A (ja) | 2007-06-01 | 2011-02-17 | ノボ・ノルデイスク・エー/エス | 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト |
| EP2190872B1 (en) | 2007-09-05 | 2018-03-14 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| EP2398822B1 (en) | 2009-02-19 | 2013-01-02 | Novo Nordisk A/S | Modification of factor viii |
| JP2013514322A (ja) | 2009-12-16 | 2013-04-25 | ノヴォ ノルディスク アー/エス | 修飾されたn末端を有するglp−1受容体アゴニスト化合物 |
| PL3326620T3 (pl) | 2010-12-16 | 2020-08-24 | Novo Nordisk A/S | Kompozycje stałe zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino)kaprylowego |
| CN102180963B (zh) | 2011-04-22 | 2014-06-25 | 中国药科大学 | 胰高血糖素样肽-1(glp-1)类似物及其应用 |
| CN110041399B (zh) | 2011-12-29 | 2023-12-12 | 诺沃—诺迪斯克有限公司 | 包含非成蛋白质性的氨基酸的二肽 |
| HUE062740T2 (hu) | 2012-03-22 | 2023-12-28 | Novo Nordisk As | GLP-1 peptidek készítményei és elõállításuk |
| CN103087178A (zh) | 2012-11-30 | 2013-05-08 | 中国药科大学 | 长效化胰高血糖素样肽-1(glp-1)类似物及其应用 |
| KR20160029079A (ko) | 2013-07-04 | 2016-03-14 | 노보 노르디스크 에이/에스 | Glp-1 유사 펩티드의 유도체 및 그것의 사용 |
| BR112016017402A2 (pt) | 2014-02-21 | 2017-10-17 | Medimmune Ltd | fusões anti-pcsk9~glp-1 e métodos para uso |
| EP3129041B1 (en) | 2014-04-07 | 2019-06-12 | Novo Nordisk A/S | Double-acylated glp-1 compounds |
| CN106999602B (zh) | 2014-11-27 | 2022-02-01 | 诺和诺德股份有限公司 | Glp-1衍生物及其用途 |
| US10392428B2 (en) | 2014-12-17 | 2019-08-27 | Novo Nordisk A/S | GLP-1 derivatives and uses thereof |
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| CN101255191A (zh) * | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| WO2012140117A1 (en) * | 2011-04-12 | 2012-10-18 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
| WO2014202727A1 (en) * | 2013-06-20 | 2014-12-24 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
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| ES2835033T3 (es) | 2021-06-21 |
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| EP3423481B1 (en) | 2020-10-07 |
| WO2017149070A1 (en) | 2017-09-08 |
| CN108699126A (zh) | 2018-10-23 |
| JP7053480B2 (ja) | 2022-04-12 |
| EP3423481A1 (en) | 2019-01-09 |
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