JP2019510006A - グリコシダーゼ阻害剤 - Google Patents
グリコシダーゼ阻害剤 Download PDFInfo
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- JP2019510006A JP2019510006A JP2018544466A JP2018544466A JP2019510006A JP 2019510006 A JP2019510006 A JP 2019510006A JP 2018544466 A JP2018544466 A JP 2018544466A JP 2018544466 A JP2018544466 A JP 2018544466A JP 2019510006 A JP2019510006 A JP 2019510006A
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- 0 O=C1*CCC1 Chemical compound O=C1*CCC1 0.000 description 8
- AYBZOZAOPVHROI-UHFFFAOYSA-N CC(C)C(c(cc1)cnc1N(CC1)CCN1C(C)c1ccc(CCO2)c2c1)O Chemical compound CC(C)C(c(cc1)cnc1N(CC1)CCN1C(C)c1ccc(CCO2)c2c1)O AYBZOZAOPVHROI-UHFFFAOYSA-N 0.000 description 1
- WKXGHQBJBZAEHT-UHFFFAOYSA-N CC(Nc1nnc(N2CCNCC2)[s]1)=O Chemical compound CC(Nc1nnc(N2CCNCC2)[s]1)=O WKXGHQBJBZAEHT-UHFFFAOYSA-N 0.000 description 1
- OOXRMWMEAQNRLM-UHFFFAOYSA-N CC(c(cc1)cc2c1nccn2)N(CC1)CCN1c1ncc(C2(CCOCC2)O)cc1 Chemical compound CC(c(cc1)cc2c1nccn2)N(CC1)CCN1c1ncc(C2(CCOCC2)O)cc1 OOXRMWMEAQNRLM-UHFFFAOYSA-N 0.000 description 1
- XBMXBVTVBKTLMF-UHFFFAOYSA-N CC(c(cc1)cc2c1nccn2)N(CC1)CCN1c1nnc(CNC(C)=O)[s]1 Chemical compound CC(c(cc1)cc2c1nccn2)N(CC1)CCN1c1nnc(CNC(C)=O)[s]1 XBMXBVTVBKTLMF-UHFFFAOYSA-N 0.000 description 1
- AGXVXBHTDDHKLB-UHFFFAOYSA-N CC(c1cc(OCC2)c2cc1)N(CC1)CCC1[n]1ncc(F)c1 Chemical compound CC(c1cc(OCC2)c2cc1)N(CC1)CCC1[n]1ncc(F)c1 AGXVXBHTDDHKLB-UHFFFAOYSA-N 0.000 description 1
- KOVYKKXRTWGGDK-UHFFFAOYSA-N CC(c1cc(OCC2)c2cc1)N(CC1)CCN1c1ncc(C)cn1 Chemical compound CC(c1cc(OCC2)c2cc1)N(CC1)CCN1c1ncc(C)cn1 KOVYKKXRTWGGDK-UHFFFAOYSA-N 0.000 description 1
- IUUHAMRTURMEFF-UHFFFAOYSA-N CC(c1cc2ncc[n]2cc1)N1CCNCC1 Chemical compound CC(c1cc2ncc[n]2cc1)N1CCNCC1 IUUHAMRTURMEFF-UHFFFAOYSA-N 0.000 description 1
- WZBBMYZFDDSVCW-UHFFFAOYSA-N CC(c1cc2nccnc2cc1)N(CC1)CCN1c1ccc(C2(CCCCC2)O)cn1 Chemical compound CC(c1cc2nccnc2cc1)N(CC1)CCN1c1ccc(C2(CCCCC2)O)cn1 WZBBMYZFDDSVCW-UHFFFAOYSA-N 0.000 description 1
- UDZOOLTXUPDDLO-UHFFFAOYSA-N CC(c1nc(nccc2)c2cc1)N(CC1)CCN1c1ncc(C(C(F)(F)F)O)cn1 Chemical compound CC(c1nc(nccc2)c2cc1)N(CC1)CCN1c1ncc(C(C(F)(F)F)O)cn1 UDZOOLTXUPDDLO-UHFFFAOYSA-N 0.000 description 1
- YCCRRIYVKYVTHT-UHFFFAOYSA-N CCCN(CCN)C(C)C Chemical compound CCCN(CCN)C(C)C YCCRRIYVKYVTHT-UHFFFAOYSA-N 0.000 description 1
- WIEMWLGSWIIWEG-LBPRGKRZSA-N C[C@@H](c1cc(OCC2)c2cc1)N(CC1)CCN1c1nnc(NC(C)=O)[s]1 Chemical compound C[C@@H](c1cc(OCC2)c2cc1)N(CC1)CCN1c1nnc(NC(C)=O)[s]1 WIEMWLGSWIIWEG-LBPRGKRZSA-N 0.000 description 1
- FXBDZRPZSUCKMO-UHFFFAOYSA-N OC1(COC1)c(cn1)cnc1Cl Chemical compound OC1(COC1)c(cn1)cnc1Cl FXBDZRPZSUCKMO-UHFFFAOYSA-N 0.000 description 1
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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| JP2023507180A (ja) * | 2019-12-18 | 2023-02-21 | ヤンセン ファーマシューティカ エヌ.ベー. | Oga阻害剤化合物 |
| JP2024518530A (ja) * | 2021-05-14 | 2024-05-01 | ビーエム ファーマ コンサルティング ピーティーワイ リミテッド | ウイルス感染の予防及び治療のための二環式複素環化合物 |
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- 2017-02-24 MA MA043677A patent/MA43677A/fr unknown
- 2017-02-24 AU AU2017222958A patent/AU2017222958B2/en not_active Revoked
- 2017-02-24 WO PCT/EP2017/054268 patent/WO2017144633A1/en not_active Ceased
- 2017-02-24 CN CN201780011547.3A patent/CN108884077A/zh active Pending
- 2017-02-24 CA CA3012560A patent/CA3012560A1/en not_active Withdrawn
- 2017-02-24 US US16/078,159 patent/US11612599B2/en active Active
- 2017-02-24 KR KR1020187025792A patent/KR20180132629A/ko not_active Withdrawn
- 2017-02-24 EP EP17707008.3A patent/EP3419971B1/en active Active
- 2017-02-24 MX MX2018010192A patent/MX2018010192A/es unknown
- 2017-08-24 EA EA201991697A patent/EA201991697A1/ru unknown
- 2017-08-24 JP JP2019545961A patent/JP7082446B2/ja active Active
- 2017-08-24 CN CN201780089984.7A patent/CN110770226B/zh active Active
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2019
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| JP2019506430A (ja) * | 2016-02-25 | 2019-03-07 | エースニューロン・ソシエテ・アノニム | グリコシダーゼ阻害剤 |
| JP2023507180A (ja) * | 2019-12-18 | 2023-02-21 | ヤンセン ファーマシューティカ エヌ.ベー. | Oga阻害剤化合物 |
| JP2024518530A (ja) * | 2021-05-14 | 2024-05-01 | ビーエム ファーマ コンサルティング ピーティーワイ リミテッド | ウイルス感染の予防及び治療のための二環式複素環化合物 |
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| JP2020509003A (ja) | 2020-03-26 |
| CN110770226B (zh) | 2023-11-10 |
| CN110770226A (zh) | 2020-02-07 |
| ZA201905405B (en) | 2021-08-25 |
| EP3419971B1 (en) | 2022-04-20 |
| US20210186958A1 (en) | 2021-06-24 |
| EA201991697A1 (ru) | 2020-03-04 |
| MA43677A (fr) | 2018-11-28 |
| EP3419971A1 (en) | 2019-01-02 |
| US11612599B2 (en) | 2023-03-28 |
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| WO2017144633A1 (en) | 2017-08-31 |
| AU2017222958B2 (en) | 2019-07-18 |
| CA3012560A1 (en) | 2017-08-31 |
| JP7082446B2 (ja) | 2022-06-08 |
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| HK1240575B (en) | Glycosidase inhibitors | |
| EA041319B1 (ru) | Ингибиторы гликозидазы |
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