JP2019501932A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019501932A5 JP2019501932A5 JP2018536384A JP2018536384A JP2019501932A5 JP 2019501932 A5 JP2019501932 A5 JP 2019501932A5 JP 2018536384 A JP2018536384 A JP 2018536384A JP 2018536384 A JP2018536384 A JP 2018536384A JP 2019501932 A5 JP2019501932 A5 JP 2019501932A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsaturated
- substituted
- phenyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CN(C)[C@](*)(CC1)CC[C@@]1(CN1*)N(CC2(*)CC2)C1=O Chemical compound CN(C)[C@](*)(CC1)CC[C@@]1(CN1*)N(CC2(*)CC2)C1=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16151015.1 | 2016-01-13 | ||
| EP16151015 | 2016-01-13 | ||
| PCT/EP2017/025008 WO2017121650A1 (en) | 2016-01-13 | 2017-01-13 | 8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501932A JP2019501932A (ja) | 2019-01-24 |
| JP2019501932A5 true JP2019501932A5 (https=) | 2021-03-18 |
| JP6917379B2 JP6917379B2 (ja) | 2021-08-11 |
Family
ID=55129636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536384A Expired - Fee Related JP6917379B2 (ja) | 2016-01-13 | 2017-01-13 | ８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 |
Country Status (26)
| Country | Link |
|---|---|
| US (7) | US20170197949A1 (https=) |
| EP (1) | EP3402782B1 (https=) |
| JP (1) | JP6917379B2 (https=) |
| KR (1) | KR20180097734A (https=) |
| CN (1) | CN108602778B (https=) |
| AR (1) | AR107359A1 (https=) |
| AU (1) | AU2017206911B2 (https=) |
| BR (1) | BR112018014301B1 (https=) |
| CA (1) | CA3011182A1 (https=) |
| CL (1) | CL2018001909A1 (https=) |
| CO (1) | CO2018008450A2 (https=) |
| CY (1) | CY1123366T1 (https=) |
| DK (1) | DK3402782T3 (https=) |
| EA (1) | EA034898B1 (https=) |
| EC (1) | ECSP18060875A (https=) |
| ES (1) | ES2821969T3 (https=) |
| HR (1) | HRP20201660T1 (https=) |
| HU (1) | HUE051642T2 (https=) |
| IL (1) | IL260488B (https=) |
| LT (1) | LT3402782T (https=) |
| MX (1) | MX379359B (https=) |
| PT (1) | PT3402782T (https=) |
| RS (1) | RS60855B1 (https=) |
| SI (1) | SI3402782T1 (https=) |
| TW (1) | TWI654181B (https=) |
| WO (1) | WO2017121650A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| JP6854823B2 (ja) | 2016-01-13 | 2021-04-07 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 |
| EP3722284B1 (en) | 2016-01-13 | 2025-01-22 | Grünenthal GmbH | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| PL3402783T3 (pl) | 2016-01-13 | 2020-08-24 | Grünenthal GmbH | Pochodne 3-(karboksyetylo)-8-amino-2-okso-1,3-diazaspiro-[4.5]-dekanu |
| US20170197947A1 (en) | 2016-01-13 | 2017-07-13 | Gruenenthal Gmbh | 3-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives |
| WO2019039852A1 (ko) | 2017-08-22 | 2019-02-28 | 주식회사 엘지화학 | 방열 소재 디스펜싱 장치의 결정방법 |
| JP7446316B2 (ja) | 2019-01-11 | 2024-03-08 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 置換ピロリジンアミドｉｉｉ |
| CN110092790B (zh) * | 2019-06-11 | 2020-07-24 | 东北农业大学 | 一种生物碱类化合物及其制备方法和应用 |
| US20240400537A1 (en) | 2023-04-25 | 2024-12-05 | Gruenenthal Gmbh | Cis-8-(3,5-difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2734265B1 (fr) | 1995-05-17 | 1997-06-13 | Adir | Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant |
| KR100855204B1 (ko) | 2001-04-18 | 2008-09-01 | 유로-셀티크 소시에떼 아노뉨 | 노시셉틴 유사체 |
| DE10130020A1 (de) | 2001-06-25 | 2003-12-04 | Gruenenthal Gmbh | Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate |
| DE10135636A1 (de) * | 2001-07-17 | 2003-02-06 | Gruenenthal Gmbh | Substituierte 4-Aminocyclohexanole |
| DE10210195B4 (de) | 2002-03-07 | 2005-12-15 | Schwarz Pharma Ag | Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz |
| WO2004005293A2 (en) | 2002-07-05 | 2004-01-15 | Targacept, Inc. | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| US20080287478A1 (en) | 2003-05-23 | 2008-11-20 | Lars Bo Laurenborg Hansen | Nociceptin Analogues and Uses Thereof |
| JO2676B1 (en) | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
| DE102005023784A1 (de) | 2005-05-19 | 2006-11-30 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005044813A1 (de) | 2005-05-19 | 2007-10-04 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005030051A1 (de) | 2005-06-27 | 2006-12-28 | Grünenthal GmbH | Substituierte 1-Oxa-3,8-diazaspiro[4,5]-decan-2-on-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102006019597A1 (de) | 2006-04-27 | 2007-10-31 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| JP5079011B2 (ja) | 2006-10-19 | 2012-11-21 | エフ．ホフマン−ラ ロシュ アーゲー | 糖尿病のための１１β−ＨＳＤ１阻害剤としてのイミダゾロン及びイミダゾリジノン誘導体 |
| JP5490677B2 (ja) | 2007-04-09 | 2014-05-14 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 不安及び鬱病の処置のためのｏｒｌ−１受容体リガンドとしての１，３，８−三置換−１，３，８−トリアザ−スピロ［４．５］デカン−４−オン誘導体 |
| ES2464102T3 (es) * | 2008-03-27 | 2014-05-30 | Grünenthal GmbH | Derivados de 4-aminociclohexano sustituidos |
| TW201038572A (en) | 2009-03-25 | 2010-11-01 | Gruenenthal Gmbh | Substituted spiro-amide compounds |
| WO2010151815A2 (en) | 2009-06-25 | 2010-12-29 | Abbott Laboratories | 3,9-diazaspiro[5,5]undecane amides and ureas and methods of use thereof |
| TWI582092B (zh) | 2010-07-28 | 2017-05-11 | 歌林達股份有限公司 | 順式－四氫－螺旋（環己烷－１,１’－吡啶［３,４－b］吲哚）－４－胺－衍生物 |
| EP2938341B1 (en) * | 2012-12-31 | 2018-09-05 | Sunovion Pharmaceuticals Inc. | Heterocyclic compounds and methods of use thereof |
| JP6643545B2 (ja) * | 2014-03-14 | 2020-02-12 | ラクオリア創薬株式会社 | Ｔｒｐｍ８拮抗剤としてのアザスピロ誘導体 |
| WO2015192039A1 (en) | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Heterocyclic morphinan derivatives and use thereof |
| EP3722284B1 (en) | 2016-01-13 | 2025-01-22 | Grünenthal GmbH | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| TWI730032B (zh) | 2016-01-13 | 2021-06-11 | 美商必治妥美雅史谷比公司 | 作為ｒｏｃｋ抑制劑之螺庚烷水楊酸醯胺及相關化合物 |
| PL3402783T3 (pl) | 2016-01-13 | 2020-08-24 | Grünenthal GmbH | Pochodne 3-(karboksyetylo)-8-amino-2-okso-1,3-diazaspiro-[4.5]-dekanu |
| US10822385B2 (en) | 2016-01-13 | 2020-11-03 | Novo Nordisk A/S | EGF(A) analogues with fatty acid substituents |
| JP6854823B2 (ja) | 2016-01-13 | 2021-04-07 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 |
| US20170197947A1 (en) | 2016-01-13 | 2017-07-13 | Gruenenthal Gmbh | 3-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives |
-
2017
- 2017-01-13 SI SI201730473T patent/SI3402782T1/sl unknown
- 2017-01-13 CN CN201780006515.4A patent/CN108602778B/zh not_active Expired - Fee Related
- 2017-01-13 EA EA201891608A patent/EA034898B1/ru not_active IP Right Cessation
- 2017-01-13 CO CONC2018/0008450A patent/CO2018008450A2/es unknown
- 2017-01-13 MX MX2018008645A patent/MX379359B/es unknown
- 2017-01-13 US US15/405,627 patent/US20170197949A1/en not_active Abandoned
- 2017-01-13 WO PCT/EP2017/025008 patent/WO2017121650A1/en not_active Ceased
- 2017-01-13 BR BR112018014301-4A patent/BR112018014301B1/pt not_active IP Right Cessation
- 2017-01-13 TW TW106101127A patent/TWI654181B/zh not_active IP Right Cessation
- 2017-01-13 AR ARP170100094A patent/AR107359A1/es unknown
- 2017-01-13 HR HRP20201660TT patent/HRP20201660T1/hr unknown
- 2017-01-13 AU AU2017206911A patent/AU2017206911B2/en not_active Ceased
- 2017-01-13 KR KR1020187021559A patent/KR20180097734A/ko active Pending
- 2017-01-13 JP JP2018536384A patent/JP6917379B2/ja not_active Expired - Fee Related
- 2017-01-13 ES ES17700390T patent/ES2821969T3/es active Active
- 2017-01-13 RS RS20201155A patent/RS60855B1/sr unknown
- 2017-01-13 EP EP17700390.2A patent/EP3402782B1/en active Active
- 2017-01-13 LT LTEP17700390.2T patent/LT3402782T/lt unknown
- 2017-01-13 PT PT177003902T patent/PT3402782T/pt unknown
- 2017-01-13 CA CA3011182A patent/CA3011182A1/en active Pending
- 2017-01-13 DK DK17700390.2T patent/DK3402782T3/da active
- 2017-01-13 HU HUE17700390A patent/HUE051642T2/hu unknown
-
2018
- 2018-05-21 US US15/984,995 patent/US20180273516A1/en not_active Abandoned
- 2018-07-09 IL IL260488A patent/IL260488B/en unknown
- 2018-07-13 CL CL2018001909A patent/CL2018001909A1/es unknown
- 2018-08-13 EC ECSENADI201860875A patent/ECSP18060875A/es unknown
- 2018-12-03 US US16/207,916 patent/US20190100515A1/en not_active Abandoned
-
2019
- 2019-06-24 US US16/450,259 patent/US10793556B2/en active Active
-
2020
- 2020-08-31 US US17/007,150 patent/US20200399255A1/en not_active Abandoned
- 2020-09-28 CY CY20201100913T patent/CY1123366T1/el unknown
-
2021
- 2021-03-01 US US17/188,706 patent/US20210179595A1/en not_active Abandoned
-
2023
- 2023-01-30 US US18/103,371 patent/US20230183222A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019501932A5 (https=) | ||
| RU2422450C2 (ru) | Новые фосфорсодержащие тиромиметики | |
| JP2019501939A5 (https=) | ||
| JP2013532726A5 (https=) | ||
| JP2008520630A5 (https=) | ||
| JP2010511018A5 (https=) | ||
| JP2002524463A5 (https=) | ||
| KR960022553A (ko) | 신규한 에리스로마이신 유도체, 그의 제조 방법 및 의약으로서의 용도 | |
| DE3150916C2 (https=) | ||
| RU2001130163A (ru) | Производные пиперидина и фармацевтическая композиция на их основе | |
| JP2015535261A5 (https=) | ||
| JP2018511647A5 (https=) | ||
| JP2013545816A5 (https=) | ||
| RU2008137526A (ru) | Ингибиторы киназы, основанные на гидантоине | |
| JPH0222066B2 (https=) | ||
| RU2007130802A (ru) | Пуриновые производные в качестве агонистов рецептора а2а | |
| JP2005526773A5 (https=) | ||
| JP2007538042A5 (https=) | ||
| JPWO2023016529A5 (https=) | ||
| JP2021523109A5 (https=) | ||
| JPWO2022047031A5 (https=) | ||
| JP2020521775A5 (https=) | ||
| JPWO2023150150A5 (https=) | ||
| RU2399625C2 (ru) | Монолизиновые соли производных азола | |
| JPWO2023101981A5 (https=) |