HUE051642T2 - 8-amino-2-oxo-1,3-diaza-spiro-[4,5]-dekán származékok - Google Patents
8-amino-2-oxo-1,3-diaza-spiro-[4,5]-dekán származékokInfo
- Publication number
- HUE051642T2 HUE051642T2 HUE17700390A HUE17700390A HUE051642T2 HU E051642 T2 HUE051642 T2 HU E051642T2 HU E17700390 A HUE17700390 A HU E17700390A HU E17700390 A HUE17700390 A HU E17700390A HU E051642 T2 HUE051642 T2 HU E051642T2
- Authority
- HU
- Hungary
- Prior art keywords
- diazaspiro
- oxo
- amino
- decane derivatives
- decane
- Prior art date
Links
- VGYPDWDXIAHEIY-UHFFFAOYSA-N 8-amino-1,3-diazaspiro[4.5]decan-2-one Chemical class C1CC(N)CCC11NC(=O)NC1 VGYPDWDXIAHEIY-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16151015 | 2016-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE051642T2 true HUE051642T2 (hu) | 2021-03-01 |
Family
ID=55129636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17700390A HUE051642T2 (hu) | 2016-01-13 | 2017-01-13 | 8-amino-2-oxo-1,3-diaza-spiro-[4,5]-dekán származékok |
Country Status (26)
| Country | Link |
|---|---|
| US (7) | US20170197949A1 (https=) |
| EP (1) | EP3402782B1 (https=) |
| JP (1) | JP6917379B2 (https=) |
| KR (1) | KR20180097734A (https=) |
| CN (1) | CN108602778B (https=) |
| AR (1) | AR107359A1 (https=) |
| AU (1) | AU2017206911B2 (https=) |
| BR (1) | BR112018014301B1 (https=) |
| CA (1) | CA3011182A1 (https=) |
| CL (1) | CL2018001909A1 (https=) |
| CO (1) | CO2018008450A2 (https=) |
| CY (1) | CY1123366T1 (https=) |
| DK (1) | DK3402782T3 (https=) |
| EA (1) | EA034898B1 (https=) |
| EC (1) | ECSP18060875A (https=) |
| ES (1) | ES2821969T3 (https=) |
| HR (1) | HRP20201660T1 (https=) |
| HU (1) | HUE051642T2 (https=) |
| IL (1) | IL260488B (https=) |
| LT (1) | LT3402782T (https=) |
| MX (1) | MX379359B (https=) |
| PT (1) | PT3402782T (https=) |
| RS (1) | RS60855B1 (https=) |
| SI (1) | SI3402782T1 (https=) |
| TW (1) | TWI654181B (https=) |
| WO (1) | WO2017121650A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3402784T1 (sl) | 2016-01-13 | 2020-07-31 | Gruenenthal Gmbh | Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana |
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| CA3011176C (en) | 2016-01-13 | 2023-09-19 | Grunenthal Gmbh | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| CA3011180A1 (en) | 2016-01-13 | 2017-07-20 | Grunenthal Gmbh | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| BR112018014302B1 (pt) | 2016-01-13 | 2023-10-17 | Grünenthal GmbH | Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| WO2019039852A1 (ko) | 2017-08-22 | 2019-02-28 | 주식회사 엘지화학 | 방열 소재 디스펜싱 장치의 결정방법 |
| BR112021013557A2 (pt) | 2019-01-11 | 2021-09-21 | Grünenthal GmbH | Amidas de pirrolidina substituídas iii |
| CN110092790B (zh) * | 2019-06-11 | 2020-07-24 | 东北农业大学 | 一种生物碱类化合物及其制备方法和应用 |
| US20240400537A1 (en) | 2023-04-25 | 2024-12-05 | Gruenenthal Gmbh | Cis-8-(3,5-difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2734265B1 (fr) | 1995-05-17 | 1997-06-13 | Adir | Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant |
| RU2268883C2 (ru) | 2001-04-18 | 2006-01-27 | Эро-Селтик, С.А. | Аналоги ноницептина и фармацевтическая композиция на их основе |
| DE10130020A1 (de) | 2001-06-25 | 2003-12-04 | Gruenenthal Gmbh | Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate |
| DE10135636A1 (de) * | 2001-07-17 | 2003-02-06 | Gruenenthal Gmbh | Substituierte 4-Aminocyclohexanole |
| DE10210195B4 (de) | 2002-03-07 | 2005-12-15 | Schwarz Pharma Ag | Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz |
| DK1519939T5 (da) | 2002-07-05 | 2011-01-24 | Targacept Inc | N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| EP1628978A2 (en) | 2003-05-23 | 2006-03-01 | Zealand Pharma A/S | Triaza-spiro compounds as nociceptin analogues and uses thereof |
| JO2676B1 (en) | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
| DE102005044813A1 (de) | 2005-05-19 | 2007-10-04 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005023784A1 (de) | 2005-05-19 | 2006-11-30 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005030051A1 (de) | 2005-06-27 | 2006-12-28 | Grünenthal GmbH | Substituierte 1-Oxa-3,8-diazaspiro[4,5]-decan-2-on-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102006019597A1 (de) | 2006-04-27 | 2007-10-31 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| CN101553474B (zh) | 2006-10-19 | 2013-02-27 | 霍夫曼-拉罗奇有限公司 | 作为糖尿病用11b-HSD1抑制剂的咪唑啉酮和咪唑烷酮衍生物 |
| CA2683598C (en) | 2007-04-09 | 2015-11-17 | Janssen Pharmaceutica Nv | 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression |
| CA2719735A1 (en) * | 2008-03-27 | 2009-10-01 | Gruenenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| TW201038572A (en) | 2009-03-25 | 2010-11-01 | Gruenenthal Gmbh | Substituted spiro-amide compounds |
| WO2010151815A2 (en) | 2009-06-25 | 2010-12-29 | Abbott Laboratories | 3,9-diazaspiro[5,5]undecane amides and ureas and methods of use thereof |
| TWI582092B (zh) | 2010-07-28 | 2017-05-11 | 歌林達股份有限公司 | 順式－四氫－螺旋（環己烷－１,１’－吡啶［３,４－b］吲哚）－４－胺－衍生物 |
| WO2014106238A1 (en) * | 2012-12-31 | 2014-07-03 | Fang, Qun, Kevin | Heterocyclic compounds and methods of use thereof |
| TWI674257B (zh) * | 2014-03-14 | 2019-10-11 | 日商拉夸里亞創藥股份有限公司 | 作為ｔｒｐｍ８拮抗劑之氮雜螺衍生物 |
| WO2015192039A1 (en) | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Heterocyclic morphinan derivatives and use thereof |
| AR107354A1 (es) | 2016-01-13 | 2018-04-18 | Bristol Myers Squibb Co | Salicilamidas espiroheptanos y compuestos relacionados como inhibidores de rock |
| BR112018014302B1 (pt) | 2016-01-13 | 2023-10-17 | Grünenthal GmbH | Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| SI3402811T1 (sl) | 2016-01-13 | 2022-06-30 | Novo Nordisk A/S | Analogi EGF(A) z maščobnokislinskimi substituenti |
| CA3011180A1 (en) | 2016-01-13 | 2017-07-20 | Grunenthal Gmbh | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| CA3011176C (en) | 2016-01-13 | 2023-09-19 | Grunenthal Gmbh | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| SI3402784T1 (sl) | 2016-01-13 | 2020-07-31 | Gruenenthal Gmbh | Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana |
-
2017
- 2017-01-13 SI SI201730473T patent/SI3402782T1/sl unknown
- 2017-01-13 RS RS20201155A patent/RS60855B1/sr unknown
- 2017-01-13 EP EP17700390.2A patent/EP3402782B1/en active Active
- 2017-01-13 CO CONC2018/0008450A patent/CO2018008450A2/es unknown
- 2017-01-13 TW TW106101127A patent/TWI654181B/zh not_active IP Right Cessation
- 2017-01-13 JP JP2018536384A patent/JP6917379B2/ja not_active Expired - Fee Related
- 2017-01-13 ES ES17700390T patent/ES2821969T3/es active Active
- 2017-01-13 MX MX2018008645A patent/MX379359B/es unknown
- 2017-01-13 LT LTEP17700390.2T patent/LT3402782T/lt unknown
- 2017-01-13 CN CN201780006515.4A patent/CN108602778B/zh not_active Expired - Fee Related
- 2017-01-13 AR ARP170100094A patent/AR107359A1/es unknown
- 2017-01-13 CA CA3011182A patent/CA3011182A1/en active Pending
- 2017-01-13 BR BR112018014301-4A patent/BR112018014301B1/pt not_active IP Right Cessation
- 2017-01-13 AU AU2017206911A patent/AU2017206911B2/en not_active Ceased
- 2017-01-13 HU HUE17700390A patent/HUE051642T2/hu unknown
- 2017-01-13 DK DK17700390.2T patent/DK3402782T3/da active
- 2017-01-13 KR KR1020187021559A patent/KR20180097734A/ko active Pending
- 2017-01-13 EA EA201891608A patent/EA034898B1/ru not_active IP Right Cessation
- 2017-01-13 PT PT177003902T patent/PT3402782T/pt unknown
- 2017-01-13 US US15/405,627 patent/US20170197949A1/en not_active Abandoned
- 2017-01-13 WO PCT/EP2017/025008 patent/WO2017121650A1/en not_active Ceased
- 2017-01-13 HR HRP20201660TT patent/HRP20201660T1/hr unknown
-
2018
- 2018-05-21 US US15/984,995 patent/US20180273516A1/en not_active Abandoned
- 2018-07-09 IL IL260488A patent/IL260488B/en unknown
- 2018-07-13 CL CL2018001909A patent/CL2018001909A1/es unknown
- 2018-08-13 EC ECSENADI201860875A patent/ECSP18060875A/es unknown
- 2018-12-03 US US16/207,916 patent/US20190100515A1/en not_active Abandoned
-
2019
- 2019-06-24 US US16/450,259 patent/US10793556B2/en active Active
-
2020
- 2020-08-31 US US17/007,150 patent/US20200399255A1/en not_active Abandoned
- 2020-09-28 CY CY20201100913T patent/CY1123366T1/el unknown
-
2021
- 2021-03-01 US US17/188,706 patent/US20210179595A1/en not_active Abandoned
-
2023
- 2023-01-30 US US18/103,371 patent/US20230183222A1/en not_active Abandoned
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| HRP20180585T1 (hr) | Spojevi 2,7-diazaspiro[3.5]nonana | |
| PT3419979T (pt) | Compostos de 6,7-dihidro-5h-pirazolo[5,1-b][1,3]oxazina-2-carboxamida | |
| DK3368519T3 (da) | Hidtil ukendte, heterocykliske antiøstrogener | |
| SG11201803584RA (en) | 1,4-dicarbonyl-piperidyl derivatives | |
| CL2016001885A1 (es) | Bolsa hidrodegradable. | |
| DK3372589T3 (da) | Pyrimidinderivat | |
| LT4056557T (lt) | Benzazepino dariniai, naudotini kaip vaistai | |
| BR112016002560A2 (pt) | derivados de pirrolona usados como herbicidas. | |
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| HUE040133T2 (hu) | Szubsztituált azaspiro(4.5)dekán származékok | |
| EP3595647A4 (en) | ARYL-PIPERIDINE DERIVATIVES |