JP2024546951A5 - - Google Patents
Info
- Publication number
- JP2024546951A5 JP2024546951A5 JP2024535951A JP2024535951A JP2024546951A5 JP 2024546951 A5 JP2024546951 A5 JP 2024546951A5 JP 2024535951 A JP2024535951 A JP 2024535951A JP 2024535951 A JP2024535951 A JP 2024535951A JP 2024546951 A5 JP2024546951 A5 JP 2024546951A5
- Authority
- JP
- Japan
- Prior art keywords
- branched
- linear
- compound according
- alkyl
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163290396P | 2021-12-16 | 2021-12-16 | |
| US63/290,396 | 2021-12-16 | ||
| PCT/US2022/081704 WO2023114937A2 (en) | 2021-12-16 | 2022-12-15 | Fluorinated cationic lipids for use in lipid nanoparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024546951A JP2024546951A (ja) | 2024-12-26 |
| JP2024546951A5 true JP2024546951A5 (https=) | 2025-12-12 |
Family
ID=85157138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024535951A Pending JP2024546951A (ja) | 2021-12-16 | 2022-12-15 | 脂質ナノ粒子に用いるフッ化カチオン性脂質 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250059131A1 (https=) |
| EP (1) | EP4448482A2 (https=) |
| JP (1) | JP2024546951A (https=) |
| KR (1) | KR20240122872A (https=) |
| CN (1) | CN118647599A (https=) |
| CA (1) | CA3242399A1 (https=) |
| IL (1) | IL313484A (https=) |
| WO (1) | WO2023114937A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025126071A1 (en) | 2023-12-14 | 2025-06-19 | Pfizer Inc. | Rna molecules |
| WO2025166325A1 (en) | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025186725A2 (en) | 2024-03-06 | 2025-09-12 | Pfizer Inc. | Improved lnp formulations and uses thereof |
| TW202543585A (zh) | 2024-03-08 | 2025-11-16 | 美商健臻公司 | 脂質奈米粒子 |
| WO2025213138A1 (en) | 2024-04-05 | 2025-10-09 | Editas Medicine, Inc. | Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma |
| WO2025231114A1 (en) | 2024-05-01 | 2025-11-06 | Acuitas Therapeutics, Inc. | Method of using lipid nanoparticles for intramuscular delivery |
| WO2025240833A1 (en) | 2024-05-17 | 2025-11-20 | Acuitas Therapeutics, Inc. | Galnac lipid compounds for use in lipid nanoparticles |
| WO2026018181A1 (en) | 2024-07-17 | 2026-01-22 | Pfizer Inc. | Immunogenic compositions and uses thereof |
| WO2026030375A2 (en) | 2024-07-30 | 2026-02-05 | Genzyme Corporation | Lipid nanoparticles and methods of manufacture and use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6197553B1 (en) | 1994-07-15 | 2001-03-06 | Merck & Co., Inc. | Method for large scale plasmid purification |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| CN101267805A (zh) | 2005-07-27 | 2008-09-17 | 普洛体维生物治疗公司 | 制造脂质体的系统和方法 |
| AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| WO2013016058A1 (en) | 2011-07-22 | 2013-01-31 | Merck Sharp & Dohme Corp. | Novel bis-nitrogen containing cationic lipids for oligonucleotide delivery |
| WO2013086373A1 (en) * | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Lipids for the delivery of active agents |
| HUE060907T2 (hu) | 2014-06-25 | 2023-04-28 | Acuitas Therapeutics Inc | Új lipidek és lipid nanorészecske formulációk nukleinsavak bevitelére |
| PT3313829T (pt) | 2015-06-29 | 2024-07-08 | Acuitas Therapeutics Inc | Formulações de lípidos e de nanopartículas lipídicas para a administração de ácidos nucleicos |
| MX2020007944A (es) * | 2018-02-01 | 2020-11-24 | Tufts College | Nanocomplejos similares a los lípidos y sus usos. |
| CN113387825A (zh) * | 2021-06-10 | 2021-09-14 | 福州大学 | 长链烷基酯胺类化合物或含氟长链烷基酯胺类化合物及其公斤级制备方法 |
-
2022
- 2022-12-15 US US18/720,483 patent/US20250059131A1/en active Pending
- 2022-12-15 CN CN202280090898.9A patent/CN118647599A/zh active Pending
- 2022-12-15 WO PCT/US2022/081704 patent/WO2023114937A2/en not_active Ceased
- 2022-12-15 KR KR1020247023908A patent/KR20240122872A/ko active Pending
- 2022-12-15 IL IL313484A patent/IL313484A/en unknown
- 2022-12-15 EP EP22851332.1A patent/EP4448482A2/en active Pending
- 2022-12-15 CA CA3242399A patent/CA3242399A1/en active Pending
- 2022-12-15 JP JP2024535951A patent/JP2024546951A/ja active Pending
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