JP2022539089A5 - - Google Patents

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Publication number
JP2022539089A5
JP2022539089A5 JP2021577003A JP2021577003A JP2022539089A5 JP 2022539089 A5 JP2022539089 A5 JP 2022539089A5 JP 2021577003 A JP2021577003 A JP 2021577003A JP 2021577003 A JP2021577003 A JP 2021577003A JP 2022539089 A5 JP2022539089 A5 JP 2022539089A5
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JP
Japan
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JP2021577003A
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Japanese (ja)
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JP7420841B2 (ja
JPWO2021000041A5 (https=
JP2022539089A (ja
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Priority claimed from PCT/CA2020/050897 external-priority patent/WO2021000041A1/en
Publication of JP2022539089A publication Critical patent/JP2022539089A/ja
Publication of JP2022539089A5 publication Critical patent/JP2022539089A5/ja
Publication of JPWO2021000041A5 publication Critical patent/JPWO2021000041A5/ja
Priority to JP2024002304A priority Critical patent/JP7667327B2/ja
Application granted granted Critical
Publication of JP7420841B2 publication Critical patent/JP7420841B2/ja
Priority to JP2025065109A priority patent/JP2025105627A/ja
Active legal-status Critical Current
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JP2021577003A 2019-06-29 2020-06-26 核酸送達のためのイオン化可能な脂質 Active JP7420841B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024002304A JP7667327B2 (ja) 2019-06-29 2024-01-11 核酸送達のためのイオン化可能な脂質
JP2025065109A JP2025105627A (ja) 2019-06-29 2025-04-10 核酸送達のためのイオン化可能な脂質

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962868900P 2019-06-29 2019-06-29
US62/868,900 2019-06-29
US202063009042P 2020-04-13 2020-04-13
US63/009,042 2020-04-13
PCT/CA2020/050897 WO2021000041A1 (en) 2019-06-29 2020-06-26 Ionizable lipids for nucleic acid delivery

Related Child Applications (1)

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JP2024002304A Division JP7667327B2 (ja) 2019-06-29 2024-01-11 核酸送達のためのイオン化可能な脂質

Publications (4)

Publication Number Publication Date
JP2022539089A JP2022539089A (ja) 2022-09-07
JP2022539089A5 true JP2022539089A5 (https=) 2023-07-04
JPWO2021000041A5 JPWO2021000041A5 (https=) 2023-07-04
JP7420841B2 JP7420841B2 (ja) 2024-01-23

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021577003A Active JP7420841B2 (ja) 2019-06-29 2020-06-26 核酸送達のためのイオン化可能な脂質
JP2024002304A Active JP7667327B2 (ja) 2019-06-29 2024-01-11 核酸送達のためのイオン化可能な脂質
JP2025065109A Pending JP2025105627A (ja) 2019-06-29 2025-04-10 核酸送達のためのイオン化可能な脂質

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JP2024002304A Active JP7667327B2 (ja) 2019-06-29 2024-01-11 核酸送達のためのイオン化可能な脂質
JP2025065109A Pending JP2025105627A (ja) 2019-06-29 2025-04-10 核酸送達のためのイオン化可能な脂質

Country Status (7)

Country Link
US (1) US20220378917A1 (https=)
EP (1) EP3990441A4 (https=)
JP (3) JP7420841B2 (https=)
KR (2) KR102928289B1 (https=)
CN (1) CN115279743B (https=)
CA (1) CA3143578A1 (https=)
WO (1) WO2021000041A1 (https=)

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CA3112837A1 (en) * 2018-10-19 2020-04-23 Translate Bio, Inc. Pumpless encapsulation of messenger rna
CZ310613B6 (cs) * 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
IL303195A (en) 2020-11-25 2023-07-01 Akagera Medicines Inc Lipid nanoparticles for delivery of nucleic acids and related methods of use
CN113993839B (zh) * 2021-02-05 2024-02-09 嘉晨西海(杭州)生物技术有限公司 一种可离子化脂质分子、其制备方法及其在制备脂质纳米颗粒中的应用
CN112961065B (zh) * 2021-02-05 2023-03-14 嘉晨西海(杭州)生物技术有限公司 一种可电离脂质分子及其制备方法及其在制备脂质纳米颗粒的应用
CN114149337B (zh) * 2021-07-07 2022-04-29 天津键凯科技有限公司 一种用于核酸递送的新型可电离脂质及其lnp组合物
KR20230017730A (ko) 2021-07-27 2023-02-06 에스케이바이오사이언스(주) 단백질 발현을 위한 mRNA와 이를 위한 주형
TW202328067A (zh) 2021-09-14 2023-07-16 美商雷納嘉德醫療管理公司 環狀脂質及其使用方法
CN118317944A (zh) 2021-09-14 2024-07-09 雷纳嘉德医疗管理公司 非环状脂质及其使用方法
US11510975B1 (en) 2021-11-29 2022-11-29 Replicate Bioscience, Inc. Compositions and methods for inducing ESR1, PI3K, HER2, and HER3 immune responses
CA3143650A1 (en) * 2021-12-22 2023-06-22 Providence Therapeutics Holdings Inc. Lipids and compositions thereof
EP4531819A2 (en) 2022-05-25 2025-04-09 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
WO2024006863A1 (en) 2022-06-30 2024-01-04 Precision NanoSystems ULC Lipid nanoparticle formulations for vaccines
AU2023393613A1 (en) 2022-12-12 2025-06-19 Global Life Sciences Solutions Canada Ulc Lipid nanoparticles lyophilization methods and compositions
IL321425A (en) 2022-12-23 2025-08-01 Biontech Delivery Tech Gmbh compound
US12311033B2 (en) 2023-05-31 2025-05-27 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
AU2023457271A1 (en) 2023-06-28 2025-12-18 Global Life Sciences Solutions Canada Ulc Lipid nanoparticle formulations for cell therapy and related methods
CN121712495A (zh) 2023-08-21 2026-03-20 环球生命科学解决方案加拿大有限公司 用于离子流脂质纳米颗粒的制造方法和装置
WO2025049579A1 (en) 2023-08-31 2025-03-06 Global Life Sciences Solutions Canada Ulc Intranasal formulation for pulmonary delivery of nanoparticles, compositions, uses, and manufacturing methods thereof
CN119143714B (zh) * 2023-12-11 2025-06-10 仁景(苏州)生物科技有限公司 用于递送的脂质化合物和脂质纳米颗粒
WO2025219528A1 (en) 2024-04-17 2025-10-23 Global Life Sciences Solutions Canada Ulc Non-destructive plasmid delivery to immune cells
WO2025219491A1 (en) 2024-04-17 2025-10-23 Global Life Sciences Solutions Canada Ulc Method and composition for hdr template dna delivery
WO2025224267A1 (en) 2024-04-25 2025-10-30 Global Life Sciences Solutions Canada Ulc Method for producing a liquid composition including a nanoparticle, and formulation thereof
WO2026052854A1 (en) 2024-09-09 2026-03-12 Global Life Sciences Solutions Canada Ulc 3-component lipid nanoparticle compositions, uses, and manufacturing methods thereof
WO2026052844A1 (en) 2024-09-09 2026-03-12 Global Life Sciences Solutions Canada Ulc 3-component lipid nanoparticle compositions, uses, and manufacturing methods thereof

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JP5300119B2 (ja) 2007-08-28 2013-09-25 Jfeスチール株式会社 シームレス缶用表面処理鋼板、樹脂被覆鋼板及びシームレス缶
WO2009086558A1 (en) * 2008-01-02 2009-07-09 Tekmira Pharmaceuticals Corporation Improved compositions and methods for the delivery of nucleic acids
HUE037082T2 (hu) * 2008-11-10 2018-08-28 Arbutus Biopharma Corp Új lipidek és készítmények terápiás hatóanyagok szállítására
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