JP2023526783A5 - - Google Patents

Info

Publication number
JP2023526783A5
JP2023526783A5 JP2022567080A JP2022567080A JP2023526783A5 JP 2023526783 A5 JP2023526783 A5 JP 2023526783A5 JP 2022567080 A JP2022567080 A JP 2022567080A JP 2022567080 A JP2022567080 A JP 2022567080A JP 2023526783 A5 JP2023526783 A5 JP 2023526783A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
stereoisomer
solvate
acceptable salt
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022567080A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023526783A (ja
JP7804588B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/030838 external-priority patent/WO2021226206A2/en
Publication of JP2023526783A publication Critical patent/JP2023526783A/ja
Publication of JP2023526783A5 publication Critical patent/JP2023526783A5/ja
Priority to JP2026002708A priority Critical patent/JP2026063050A/ja
Application granted granted Critical
Publication of JP7804588B2 publication Critical patent/JP7804588B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022567080A 2020-05-05 2021-05-05 カンナビノイド受容体2型(cb2)調節物質及びその使用 Active JP7804588B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026002708A JP2026063050A (ja) 2020-05-05 2026-01-09 カンナビノイド受容体2型(cb2)調節物質及びその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063020489P 2020-05-05 2020-05-05
US63/020,489 2020-05-05
US202063054096P 2020-07-20 2020-07-20
US63/054,096 2020-07-20
PCT/US2021/030838 WO2021226206A2 (en) 2020-05-05 2021-05-05 Cannabinoid receptor type 2 (cb2) modulators and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026002708A Division JP2026063050A (ja) 2020-05-05 2026-01-09 カンナビノイド受容体2型(cb2)調節物質及びその使用

Publications (3)

Publication Number Publication Date
JP2023526783A JP2023526783A (ja) 2023-06-23
JP2023526783A5 true JP2023526783A5 (https=) 2024-05-15
JP7804588B2 JP7804588B2 (ja) 2026-01-22

Family

ID=76181225

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022567080A Active JP7804588B2 (ja) 2020-05-05 2021-05-05 カンナビノイド受容体2型(cb2)調節物質及びその使用
JP2026002708A Pending JP2026063050A (ja) 2020-05-05 2026-01-09 カンナビノイド受容体2型(cb2)調節物質及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026002708A Pending JP2026063050A (ja) 2020-05-05 2026-01-09 カンナビノイド受容体2型(cb2)調節物質及びその使用

Country Status (11)

Country Link
US (3) US11564928B1 (https=)
EP (1) EP4146345A2 (https=)
JP (2) JP7804588B2 (https=)
KR (1) KR20230041654A (https=)
CN (1) CN115835909A (https=)
AU (1) AU2021266732A1 (https=)
BR (1) BR112022022335A2 (https=)
CA (1) CA3181538A1 (https=)
IL (1) IL297908A (https=)
MX (1) MX2022013864A (https=)
WO (1) WO2021226206A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230041654A (ko) * 2020-05-05 2023-03-24 테온 테라퓨틱스, 인크. 칸나비노이드 수용체 유형 2 (cb2) 조정제 및 그의 용도
TW202325306A (zh) * 2021-09-02 2023-07-01 美商天恩治療有限公司 改良免疫細胞之生長及功能的方法
WO2023081730A1 (en) 2021-11-03 2023-05-11 Teon Therapeutics, Inc. 4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
CN117624134B (zh) * 2024-01-26 2024-05-03 南昌市第一医院 一种靶向降解hdac4的化合物及其制备方法和应用

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2988739B2 (ja) * 1990-04-16 1999-12-13 協和醗酵工業株式会社 1,8−ナフチリジン−2−オン誘導体
DE4227747A1 (de) 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
KR100828982B1 (ko) * 2000-12-28 2008-05-14 시오노기세이야쿠가부시키가이샤 칸나비노이드 2형 수용체 친화 작용을 갖는 피리돈 유도체
AR036993A1 (es) 2001-04-02 2004-10-20 Wyeth Corp Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
EP1467970B1 (en) * 2002-01-17 2007-08-22 Merck & Co., Inc. Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors
CN101899114A (zh) 2002-12-23 2010-12-01 惠氏公司 抗pd-1抗体及其用途
CN1875021A (zh) 2003-11-04 2006-12-06 默克公司 取代的萘啶酮衍生物
DK2439273T3 (da) 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
PT1907424E (pt) 2005-07-01 2015-10-09 Squibb & Sons Llc Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1)
AR059733A1 (es) 2006-03-07 2008-04-23 Smithkline Beecham Corp Compuesto derivado de glicina n- sustituida con heteroaromaticos bicicicos, composicion farmaceutica que lo comprende, uso para preparar un medicamento para tratar la anemia y proceso para su preparacion
ES2393326T3 (es) 2006-12-18 2012-12-20 Amgen, Inc Compuestos basados en azaquinolona que presentan actividad inhibidora de prolil hidroxilasas, composiciones y usos de los mismos
US8048894B2 (en) 2007-04-18 2011-11-01 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
BR122017025062B8 (pt) 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
WO2009053799A1 (en) * 2007-10-24 2009-04-30 Glenmark Pharmaceuticals, S.A. Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
GB0800855D0 (en) 2008-01-17 2008-02-27 Syngenta Ltd Herbicidal compounds
US8552154B2 (en) 2008-09-26 2013-10-08 Emory University Anti-PD-L1 antibodies and uses therefor
KR101050829B1 (ko) 2008-10-02 2011-07-20 서울대학교산학협력단 항 pd-1 항체 또는 항 pd-l1 항체를 포함하는 항암제
EP3255060A1 (en) 2008-12-09 2017-12-13 F. Hoffmann-La Roche AG Anti-pd-l1 antibodies and their use to enhance t-cell function
EP2482849B1 (en) 2009-09-30 2018-06-06 Memorial Sloan-Kettering Cancer Center Combination immunotherapy for the treatment of cancer
KR20130020881A (ko) * 2010-02-08 2013-03-04 알러간, 인코포레이티드 칸나비노이드-2 효능제로서 유용한 피리다진 유도체
WO2013165898A2 (en) 2012-05-01 2013-11-07 The Trustees Of The University Of Pennsylvania Compositions and methods for inhibiting resolvases
SMT202100065T1 (it) 2013-05-02 2021-03-15 Anaptysbio Inc Anticorpi diretti contro la proteina della morte programmata (pd-1)
WO2016039749A1 (en) 2014-09-11 2016-03-17 Bristol-Myers Squibb Company Macrocyclic inhibitors of the pd-1/pd-l1 and cd80 (b7-1)/pd-li protein/protein interactions
JP6777638B2 (ja) 2014-09-19 2020-10-28 マッカイ メディカル ファンデーション ザ プレスビュテロス チャーチ イン タイワン マッカイ メモリアル ホスピタル ベンゾ複素環化合物および薬剤
US20180044350A1 (en) 2015-03-10 2018-02-15 Pottayil Govindan Nair Sasikumar Therapeutic cyclic compounds as immunomodulators
BR112017019304A2 (pt) 2015-03-10 2018-05-08 Aurigene Discovery Technologies Limited compostos de 1,2,4-oxadiazol 3-substituído e tiadiazol como imunomoduladores
BR112017019307A2 (pt) 2015-03-10 2018-05-02 Aurigene Discovery Technologies Limited compostos de 1,3,4-oxadiazol 3-substituído e tiadiazol como imunomoduladores
KR102894264B1 (ko) 2015-03-10 2025-12-02 오리진 온콜로지 리미티드 면역조절제로서의 1,2,4-옥사다이아졸 및 티아다이아졸 화합물
EA201791629A1 (ru) 2015-03-10 2018-02-28 Ауриджен Дискавери Текнолоджис Лимитед 1,3,4-оксадиазольные и тиадиазольные соединения в качестве иммуномодуляторов
US10745382B2 (en) 2015-10-15 2020-08-18 Bristol-Myers Squibb Company Compounds useful as immunomodulators
WO2017070089A1 (en) 2015-10-19 2017-04-27 Incyte Corporation Heterocyclic compounds as immunomodulators
WO2017068349A1 (en) * 2015-10-23 2017-04-27 E-Therapeutics Plc Cannabinoid for use in immunotherapy
WO2017079669A1 (en) 2015-11-04 2017-05-11 Incyte Corporation Pharmaceutical compositions and methods for indoleamine 2,3-dioxygenase inhibition and indications therefor
SG10202004618TA (en) 2015-11-19 2020-06-29 Incyte Corp Heterocyclic compounds as immunomodulators
MA44075A (fr) 2015-12-17 2021-05-19 Incyte Corp Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
AU2016379372A1 (en) 2015-12-22 2018-08-02 Incyte Corporation Heterocyclic compounds as immunomodulators
EP3190103A1 (en) 2016-01-08 2017-07-12 Rijksuniversiteit Groningen Inhibitors of the pd-1/pd-l1 protein/protein interaction
US9798514B2 (en) 2016-03-09 2017-10-24 Spotify Ab System and method for color beat display in a media content environment
US20190062272A1 (en) 2016-04-13 2019-02-28 Capten Therapeutics Inc. Small molecules for immunogenic treatment of cancer
AR108396A1 (es) 2016-05-06 2018-08-15 Incyte Corp Compuestos heterocíclicos como inmunomoduladores
WO2017202275A1 (zh) 2016-05-23 2017-11-30 中国医学科学院药物研究所 溴代苄醚衍生物、及其制法和药物组合物与用途
CA3025391A1 (en) 2016-05-26 2017-11-30 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for cancer treatment
WO2017205464A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
HUE060256T2 (hu) 2016-06-20 2023-02-28 Incyte Corp Heterociklusos vegyületek mint immunmodulátorok
EA201990221A1 (ru) 2016-07-08 2019-06-28 Бристол-Маерс Сквибб Компани 1,3-дигидроксифенильные производные, применимые в качестве иммуномодуляторов
JP2019530732A (ja) 2016-08-03 2019-10-24 アライジング・インターナショナル・インコーポレイテッドArising International, Inc. 免疫モジュレータとして有用な対称または半対称化合物
US10563620B2 (en) 2016-08-12 2020-02-18 Rolls-Royce North American Technologies Inc. Expandable exhaust cone
WO2018044783A1 (en) 2016-08-29 2018-03-08 Incyte Corporation Heterocyclic compounds as immunomodulators
US10734026B2 (en) 2016-09-01 2020-08-04 Facebook, Inc. Systems and methods for dynamically providing video content based on declarative instructions
US10144706B2 (en) 2016-09-01 2018-12-04 Bristol-Myers Squibb Company Compounds useful as immunomodulators
BR102018007822A2 (pt) 2017-04-20 2018-11-06 Gilead Sciences, Inc. composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
CA3070073A1 (en) 2017-07-18 2019-01-24 Nuvation Bio Inc. 1,8-naphthyridinone compounds and uses thereof
CR20200347A (es) 2018-02-13 2020-09-23 Gilead Sciences Inc Inhibidores pd-1/pd-l1
TWI712412B (zh) 2018-04-19 2020-12-11 美商基利科學股份有限公司 Pd‐1/pd‐l1抑制劑
SG11202012425QA (en) 2018-07-13 2021-01-28 Gilead Sciences Inc Pd-1/pd-l1 inhibitors
WO2020086556A1 (en) 2018-10-24 2020-04-30 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
KR20230041654A (ko) * 2020-05-05 2023-03-24 테온 테라퓨틱스, 인크. 칸나비노이드 수용체 유형 2 (cb2) 조정제 및 그의 용도

Similar Documents

Publication Publication Date Title
JP2023526783A5 (https=)
RU2447060C2 (ru) Ингибиторы сфингозинкиназы
US6613790B2 (en) Prodrugs of COX-2 inhibitors
RU2317294C2 (ru) (имидазол-1-илметил)пиридазин в качестве блокатора nmda рецептора
JP6193922B2 (ja) ハロアルキルヘテロアリールベンズアミド化合物
JP2023500611A5 (https=)
RU2472509C2 (ru) Способ лечения артрита
JP2023510835A5 (https=)
JP7794448B2 (ja) 組み合わせ
JP2018502867A5 (https=)
JP2018503661A5 (https=)
RU2010134411A (ru) Фенилацетамидное производное
CN102317290A (zh) Stat3抑制剂及使用stat3抑制剂的治疗方法
IL286902B1 (en) Pyrrole compounds
JP2020111571A5 (https=)
JP2017509694A5 (https=)
JP2023531495A5 (https=)
JP2023507797A (ja) 組み合わせ
JP2023067881A5 (https=)
JP2016027024A5 (https=)
JP2020521775A5 (https=)
JP2023541040A5 (https=)
RU2019130589A (ru) Новые замещенные n'-гидроксикарбамимидоил-1,2,5-оксадиазольные соединения в качестве ингибиторов индоламин-2,3-диоксигеназы (ido)
RU2007117802A (ru) Арилсульфонилметильные или арилсульфонамидные производные ароматических соединений, фармацевтическая композиция на их основе и способ лечения расстройств, восприимчивых к лечению лигандами дофаминовых d3 рецепторов, с их помощью
CN114075123B (zh) 苄胺类衍生物及其制备方法与用途