|
ES324609A1
(es)
|
1966-03-24 |
1966-12-16 |
Patronato De Investigacien Cie |
Procedimiento para la preparaciën de indolil-alquil hidrazinas
|
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
JPS5666928A
(en)
|
1979-11-05 |
1981-06-05 |
Hitachi Ltd |
Pulse generating circuit
|
|
US4352795A
(en)
|
1981-01-29 |
1982-10-05 |
Warner-Lambert Company |
7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
ZW10887A1
(en)
|
1986-06-25 |
1987-10-28 |
Injectall Ltd |
Improvements in apparatus for injecting substances into liquids
|
|
DK8189A
(da)
|
1988-01-12 |
1989-07-13 |
Bunge Australia |
Antigen-antistof-konjugater, deres fremstilling og anvendelse
|
|
DE3815826A1
(de)
|
1988-05-09 |
1989-11-23 |
Henkel Kgaa |
Verfahren zur herstellung von vicinal diacyloxysubstituierten verbindungen
|
|
US5470829A
(en)
|
1988-11-17 |
1995-11-28 |
Prisell; Per |
Pharmaceutical preparation
|
|
JP2989002B2
(ja)
|
1988-12-22 |
1999-12-13 |
キリン―アムジエン・インコーポレーテツド |
化学修飾顆粒球コロニー刺激因子
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5089261A
(en)
|
1989-01-23 |
1992-02-18 |
Cetus Corporation |
Preparation of a polymer/interleukin-2 conjugate
|
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
US5122614A
(en)
|
1989-04-19 |
1992-06-16 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
ATE181732T1
(de)
|
1989-04-19 |
1999-07-15 |
Novo Nordisk As |
Aktive karbonate von polyalkylenoxyden zur modifizierung von polypeptiden
|
|
IL90193A
(en)
|
1989-05-04 |
1993-02-21 |
Biomedical Polymers Int |
Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
|
|
US5650388A
(en)
|
1989-11-22 |
1997-07-22 |
Enzon, Inc. |
Fractionated polyalkylene oxide-conjugated hemoglobin solutions
|
|
US5312808A
(en)
|
1989-11-22 |
1994-05-17 |
Enzon, Inc. |
Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
NL194941C
(nl)
|
1990-02-15 |
2003-08-04 |
Cordis Corp |
Werkwijze voor het aanbrengen van een fysiologisch actieve verbinding op een substraatoppervlak.
|
|
US5275838A
(en)
|
1990-02-28 |
1994-01-04 |
Massachusetts Institute Of Technology |
Immobilized polyethylene oxide star molecules for bioapplications
|
|
US5171264A
(en)
|
1990-02-28 |
1992-12-15 |
Massachusetts Institute Of Technology |
Immobilized polyethylene oxide star molecules for bioapplications
|
|
US5219564A
(en)
|
1990-07-06 |
1993-06-15 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
WO1992000748A1
(en)
|
1990-07-06 |
1992-01-23 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
|
FR2672053B1
(fr)
|
1991-01-30 |
1993-04-23 |
Atochem |
Polyether bloc amides, leur procede de synthese.
|
|
WO1992015683A1
(en)
|
1991-03-06 |
1992-09-17 |
MERCK Patent Gesellschaft mit beschränkter Haftung |
Humanized and chimeric monoclonal antibodies
|
|
FR2673946B1
(fr)
|
1991-03-15 |
1993-05-28 |
Atochem |
Polyether bloc amides, leur procede de synthese.
|
|
CA2101918A1
(en)
|
1991-03-18 |
1992-09-19 |
Samuel Zalipsky |
Hydrazine containing conjugates of polypeptides and glycopolypeptides with polymers
|
|
DE69233482T2
(de)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
|
|
US5281698A
(en)
|
1991-07-23 |
1994-01-25 |
Cetus Oncology Corporation |
Preparation of an activated polymer ester for protein conjugation
|
|
CA2078539C
(en)
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
GB9125979D0
(en)
|
1991-12-06 |
1992-02-05 |
Wellcome Found |
Antibody
|
|
ES2101300T3
(es)
|
1992-02-13 |
1997-07-01 |
Carlsberg As |
Polimero que contiene polietilenglicol o polipropilenglicol.
|
|
AU684041B2
(en)
|
1992-02-19 |
1997-12-04 |
Schering Corporation |
Cloning and expression of humanized monoclonal antibodies against human interleukin-4
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
AU5006993A
(en)
|
1992-08-21 |
1994-03-15 |
Enzon, Inc. |
Novel attachment of polyalkylene oxides to bio-effecting substances
|
|
US5614549A
(en)
|
1992-08-21 |
1997-03-25 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5298643A
(en)
|
1992-12-22 |
1994-03-29 |
Enzon, Inc. |
Aryl imidate activated polyalkylene oxides
|
|
US5349001A
(en)
|
1993-01-19 |
1994-09-20 |
Enzon, Inc. |
Cyclic imide thione activated polyalkylene oxides
|
|
US5321095A
(en)
|
1993-02-02 |
1994-06-14 |
Enzon, Inc. |
Azlactone activated polyalkylene oxides
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
WO1994028937A1
(en)
|
1993-06-16 |
1994-12-22 |
Enzon, Inc. |
Conjugated biodhesives
|
|
US5880131A
(en)
|
1993-10-20 |
1999-03-09 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5840900A
(en)
|
1993-10-20 |
1998-11-24 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5965566A
(en)
|
1993-10-20 |
1999-10-12 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5605976A
(en)
|
1995-05-15 |
1997-02-25 |
Enzon, Inc. |
Method of preparing polyalkylene oxide carboxylic acids
|
|
US5446090A
(en)
|
1993-11-12 |
1995-08-29 |
Shearwater Polymers, Inc. |
Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
|
|
US5618528A
(en)
|
1994-02-28 |
1997-04-08 |
Sterling Winthrop Inc. |
Biologically compatible linear block copolymers of polyalkylene oxide and peptide units
|
|
WO1995033490A1
(en)
|
1994-06-02 |
1995-12-14 |
Enzon, Inc. |
Method of solubilizing substantially water insoluble materials
|
|
US5730990A
(en)
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
|
WO1996004925A1
(en)
|
1994-08-12 |
1996-02-22 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
|
US5932462A
(en)
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
|
US5705154A
(en)
|
1995-03-08 |
1998-01-06 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-4
|
|
US5756593A
(en)
|
1995-05-15 |
1998-05-26 |
Enzon, Inc. |
Method of preparing polyalkyene oxide carboxylic acids
|
|
US5672662A
(en)
|
1995-07-07 |
1997-09-30 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
|
|
WO1997006833A1
(en)
|
1995-08-11 |
1997-02-27 |
Dendritech, Inc. |
Hyper comb-branched polymer conjugates
|
|
JPH11513669A
(ja)
|
1995-10-13 |
1999-11-24 |
アメリカ合衆国 |
ジスルフィド安定化抗体フラグメントを含む免疫毒素
|
|
PT1704878E
(pt)
|
1995-12-18 |
2013-07-17 |
Angiodevice Internat Gmbh |
Composições de polímeros reticulados e métodos para a sua utilização
|
|
US6900304B2
(en)
|
1996-01-31 |
2005-05-31 |
The Regents Of The University Of California |
Emission ratiometric indicators of phosphorylation
|
|
US8669074B2
(en)
|
1996-01-31 |
2014-03-11 |
The Regents Of The University Of California |
Chimeric phosphorylation indicator
|
|
DE69729283T2
(de)
|
1996-03-20 |
2005-05-25 |
Immunomedics, Inc. |
GLYKOSYLIERTE IgG ANTIKÖRPER
|
|
ES2273373T3
(es)
|
1996-08-02 |
2007-05-01 |
Ortho-Mcneil Pharmaceutical, Inc. |
Polipeptidos que tienen unido a su extremo n un unico polimero soluble al agua.
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
WO1998041641A1
(en)
|
1997-03-20 |
1998-09-24 |
The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services |
Recombinant antibodies and immunoconjugates targeted to cd-22 bearing cells and tumors
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
WO1998045331A2
(en)
|
1997-04-07 |
1998-10-15 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
SI1695985T1
(sl)
|
1997-04-07 |
2011-06-30 |
Genentech Inc |
Postopki za tvorbo humaniziranih protiteles z naključno mutagenezo
|
|
WO1998049198A1
(en)
|
1997-04-30 |
1998-11-05 |
Enzon, Inc. |
Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof
|
|
WO1998050435A1
(en)
|
1997-05-02 |
1998-11-12 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Immunotoxins, comprising an onc protein, directed against malignant cells
|
|
US5990237A
(en)
|
1997-05-21 |
1999-11-23 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
|
|
GB9712892D0
(en)
|
1997-06-20 |
1997-08-20 |
Eclagen Ltd |
Identification of mhc binding peptides
|
|
GB9718913D0
(en)
|
1997-09-05 |
1997-11-12 |
Glaxo Group Ltd |
Substituted oxindole derivatives
|
|
US6011042A
(en)
|
1997-10-10 |
2000-01-04 |
Enzon, Inc. |
Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
|
|
US6111107A
(en)
|
1997-11-20 |
2000-08-29 |
Enzon, Inc. |
High yield method for stereoselective acylation of tertiary alcohols
|
|
US6180095B1
(en)
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
EP1037649B1
(en)
|
1997-12-17 |
2009-09-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
US5985263A
(en)
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
|
US5965119A
(en)
|
1997-12-30 |
1999-10-12 |
Enzon, Inc. |
Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
|
|
ATE268609T1
(de)
|
1998-03-12 |
2004-06-15 |
Nektar Therapeutics Al Corp |
Polyethylenglycolderivate mit benachbarten reaktiven gruppen
|
|
US6153655A
(en)
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
|
DK1413582T3
(da)
|
1998-08-27 |
2006-07-17 |
Spirogen Ltd |
Dimere pyrrolobenzodiazepiner
|
|
US6465612B1
(en)
|
1998-09-23 |
2002-10-15 |
The Regents Of The University Of California |
Synthetic peptides, conjugation reagents and methods
|
|
EP1194167B1
(en)
|
1999-06-09 |
2009-08-19 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
HU228491B1
(en)
|
1999-10-08 |
2013-03-28 |
Nektar Therapeutics |
Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation
|
|
US6570040B2
(en)
|
2000-03-16 |
2003-05-27 |
The Regents Of The University Of California |
Chemoselective ligation
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US6911535B2
(en)
|
2000-03-22 |
2005-06-28 |
Solvlink Biosciences |
Biomolecule/polymer conjugates
|
|
US20050201981A1
(en)
|
2004-03-10 |
2005-09-15 |
Chih-Ping Liu |
Method of optimizing treatment with interferon-tau
|
|
UY27087A1
(es)
|
2001-01-05 |
2002-06-20 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
EP1448584B1
(en)
|
2001-09-26 |
2010-05-19 |
The Government of the United States of America as represented by The Secretary of Health and Human Services |
Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells
|
|
EP1485130A4
(en)
|
2002-02-21 |
2006-11-22 |
Univ Duke |
REAGENTS AND THERAPEUTIC METHODS OF AUTOIMMUNE DISEASES
|
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
US7456260B2
(en)
|
2002-06-17 |
2008-11-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Humanized antibody
|
|
AU2003264009A1
(en)
|
2002-08-15 |
2004-03-03 |
Epitomics, Inc. |
Humanized rabbit antibodies
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US8188116B2
(en)
|
2002-09-04 |
2012-05-29 |
Vanderbilt University |
Agents for therapy efficacy monitoring and deep tissue imaging
|
|
US7754884B2
(en)
|
2005-01-03 |
2010-07-13 |
Vanderbilt University |
Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
EP1592786B8
(en)
|
2003-02-11 |
2012-03-21 |
Shire Human Genetic Therapies, Inc. |
Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies using a formylglycine generating enzyme (fge)
|
|
CN100415765C
(zh)
|
2003-08-07 |
2008-09-03 |
宜康公司 |
兔单克隆抗体的人源化方法
|
|
CA2572750A1
(en)
|
2003-09-10 |
2005-03-17 |
Anil Koul |
Heterobicyclic compounds as pharmaceutically active agents
|
|
JP2007510629A
(ja)
|
2003-10-22 |
2007-04-26 |
イーライ リリー アンド カンパニー |
新規mch受容体アンタゴニスト
|
|
US20050187389A1
(en)
|
2004-01-13 |
2005-08-25 |
Ambit Biosciences Corporation |
Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
|
|
CN1560035A
(zh)
|
2004-03-12 |
2005-01-05 |
沈阳药科大学 |
5-羟基吲哚-3-羧酸脂类衍生物
|
|
WO2005113765A2
(en)
|
2004-05-06 |
2005-12-01 |
Biomarin Pharmaceutical Inc. |
Methods of activation of sulfatases and methods and compositions of using the same
|
|
MXPA06013413A
(es)
|
2004-05-19 |
2007-01-23 |
Medarex Inc |
Enlazadores quimicos y conjugados de los mismos.
|
|
BRPI0510883B8
(pt)
|
2004-06-01 |
2021-05-25 |
Genentech Inc |
composto conjugado de droga e anticorpo, composição farmacêutica, método de fabricação de composto conjugado de droga e anticorpo e usos de uma formulação, de um conjugado de droga e anticorpo e um agente quimioterapêutico e de uma combinação
|
|
MXPA06014691A
(es)
|
2004-06-30 |
2008-03-11 |
Novartis Ag |
Conjugados de anticuerpo y derivados de duocarmicina como agentes anti-tumorales.
|
|
CN101065151B
(zh)
|
2004-09-23 |
2014-12-10 |
健泰科生物技术公司 |
半胱氨酸改造的抗体和偶联物
|
|
US7314887B2
(en)
|
2004-10-25 |
2008-01-01 |
Ligand Pharmaceuticals, Inc. |
Thrombopoietin activity modulating compounds and methods
|
|
US7255012B2
(en)
|
2004-12-01 |
2007-08-14 |
Rosemount Inc. |
Process fluid flow device with variable orifice
|
|
AU2006210724A1
(en)
|
2005-02-03 |
2006-08-10 |
Antitope Limited |
Human antibodies and proteins
|
|
EP1860120B1
(en)
|
2005-02-08 |
2018-01-24 |
The Chemo-Sero-Therapeutic Research Institute |
Method for improving antibody
|
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
|
WO2007027248A2
(en)
|
2005-05-16 |
2007-03-08 |
Valeant Research & Development |
3', 5' - cyclic nucleoside analogues for treatment of hcv
|
|
ES2585357T3
(es)
|
2005-07-07 |
2016-10-05 |
Seattle Genetics, Inc. |
Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
|
|
TW200745096A
(en)
|
2005-08-23 |
2007-12-16 |
Organon Nv |
Indole derivatives
|
|
DK3184526T3
(en)
|
2005-12-13 |
2019-01-14 |
Incyte Holdings Corp |
PYRROLO [2,3-D] PYRIMIDINE DERIVATIVES AS A JANUS-KINASE INHIBITOR
|
|
EP1998799B8
(en)
|
2006-03-06 |
2014-03-05 |
Medlmmune, LLC |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CN101490087B
(zh)
*
|
2006-05-30 |
2013-11-06 |
健泰科生物技术公司 |
抗体和免疫偶联物及其用途
|
|
HRP20140172T1
(hr)
|
2006-05-30 |
2014-03-28 |
Genentech, Inc. |
Protutijela i imunokonjugati kao i njihove uporabe
|
|
EP2040698A4
(en)
|
2006-07-14 |
2011-08-10 |
Shionogi & Co |
OXIM CONNECTIONS AND ITS USE
|
|
WO2008019303A2
(en)
|
2006-08-04 |
2008-02-14 |
Enanta Pharmaceuticals, Inc. |
Pyridazinonyl macrocyclic hepatitis c serine protease inhibitors
|
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
NZ578064A
(en)
|
2006-12-01 |
2012-01-12 |
Medarex Inc |
Human antibodies that bind cd22 and uses thereof
|
|
US8729232B2
(en)
|
2008-03-27 |
2014-05-20 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
US20100184134A1
(en)
|
2009-01-12 |
2010-07-22 |
Sutro Biopharma, Inc. |
Dual charging system for selectively introducing non-native amino acids into proteins using an in vitro synthesis method
|
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
WO2010117939A1
(en)
|
2009-04-06 |
2010-10-14 |
Schering Corporation |
Hcv inhibitor and therapeutic agent combinations
|
|
AR078471A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
COMPUESTOS MAITANSINOIDES Y EL USO DE ESTOS PARA PREPARAR CONJUGADOS CON UN ANTICUERPO LOS CUALES SE UTILIZAN COMO AGENTES ANTICANCERIGENOS Y EL PROCEDIMIENTO DE PREPARACIoN DE ESTOS CONJUGADOS
|
|
PL2516460T3
(pl)
|
2009-12-22 |
2015-08-31 |
Hoffmann La Roche |
Agregacja zależna od sekwencji
|
|
KR20110093055A
(ko)
|
2010-02-11 |
2011-08-18 |
다우어드밴스드디스플레이머티리얼 유한회사 |
신규한 유기 발광 화합물 및 이를 채용하고 있는 유기 전계 발광 소자
|
|
UY33679A
(es)
|
2010-10-22 |
2012-03-30 |
Esbatech |
Anticuerpos estables y solubles
|
|
CA2819373A1
(en)
|
2010-12-09 |
2012-06-14 |
Amgen Inc. |
Bicyclic compounds as pim inhibitors
|
|
CN103415621A
(zh)
|
2011-01-14 |
2013-11-27 |
雷德伍德生物科技股份有限公司 |
醛标记免疫球蛋白多肽及其使用方法
|
|
US20170049906A1
(en)
|
2012-05-21 |
2017-02-23 |
President And Fellows Of Harvard College |
Translocation of non-natural chemical entities through anthrax protective antigen pore
|
|
US20140004097A1
(en)
|
2012-06-29 |
2014-01-02 |
Shire Human Genetic Therapies, Inc. |
Method of producing recombinant iduronate-2-sulfatase
|
|
EP3539563A1
(en)
|
2012-07-19 |
2019-09-18 |
Redwood Bioscience, Inc. |
Antibody specific for cd22 and methods of use thereof
|
|
US9439972B2
(en)
|
2012-09-10 |
2016-09-13 |
Ad Lunam Labs, Inc. |
Antifungal serum
|
|
EP2916835A4
(en)
|
2012-11-12 |
2016-07-27 |
Redwood Bioscience Inc |
COMPOUNDS AND METHOD FOR PRODUCING A CONJUGATE
|
|
US9310374B2
(en)
*
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
BR112015013444B1
(pt)
|
2012-12-13 |
2022-11-01 |
Immunomedics, Inc |
Uso de um imunoconjugado
|
|
HRP20220553T1
(hr)
|
2013-07-25 |
2022-06-10 |
Cytomx Therapeutics Inc. |
Polispecifična protutijela, polispecifična protutijela koja se mogu aktivirati i postupci uporabe navedenih protutijela
|
|
JP6745218B2
(ja)
|
2013-11-27 |
2020-08-26 |
レッドウッド バイオサイエンス, インコーポレイテッド |
ヒドラジニル−ピロロ化合物及び複合体を生成するための方法
|
|
KR102557615B1
(ko)
|
2014-06-06 |
2023-07-20 |
레드우드 바이오사이언스 인코포레이티드 |
항-her2 항체-메이탄신 컨쥬게이트 및 이것의 사용 방법
|
|
CA2973343C
(en)
|
2015-02-05 |
2023-08-08 |
R.P. Scherer Technologies, Llc |
Activated formylglycine-generating enzymes and methods of producing and using the same
|
|
CN107735104B
(zh)
|
2015-06-25 |
2022-05-03 |
免疫医疗公司 |
组合抗hla-dr抗体或抗trop-2抗体与微管抑制剂、parp抑制剂、布鲁顿激酶抑制剂或磷酸肌醇3-激酶抑制剂使癌症治疗结果显著改善
|
|
AU2016354009B2
(en)
|
2015-11-09 |
2021-05-20 |
R.P. Scherer Technologies, Llc |
Anti-CD22 antibody-maytansine conjugates and methods of use thereof
|
|
EA202091161A1
(ru)
|
2017-12-11 |
2020-09-09 |
Трайфейз Ресерч Энд Дивелопмент Iii Корп. |
Конъюгаты антител против cd22 с майтанзином, их комбинации и способы применения
|