ES2101300T3 - Polimero que contiene polietilenglicol o polipropilenglicol. - Google Patents

Polimero que contiene polietilenglicol o polipropilenglicol.

Info

Publication number
ES2101300T3
ES2101300T3 ES93903869T ES93903869T ES2101300T3 ES 2101300 T3 ES2101300 T3 ES 2101300T3 ES 93903869 T ES93903869 T ES 93903869T ES 93903869 T ES93903869 T ES 93903869T ES 2101300 T3 ES2101300 T3 ES 2101300T3
Authority
ES
Spain
Prior art keywords
glycol
polymer
peptides
proteins
propylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93903869T
Other languages
English (en)
Inventor
Morten Peter Meldal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carlsberg AS
Original Assignee
Carlsberg AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlsberg AS filed Critical Carlsberg AS
Application granted granted Critical
Publication of ES2101300T3 publication Critical patent/ES2101300T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

UN GLICOL DE POLIETILENO O POLIPROPLENO DEGRADADO, CONTENIENDO POLIMERO, EL CUAL TIENE UNA ESTRUCTURA ESPACIAL UNICA Y PUEDE DESIGNARSE ESPECIALMENTE PARA APLICACION COMO UNA RESINA CROMATOGRAFICA, O COMO UN SOPORTE SOLIDO PARA LA SINTESIS DE PEPTIDOS, OLIGONUCLETOIDOS U OLIGOSACARIDOS, O COMO UN SUSTRATO PARA LA INMOVILIZACION DE PROTEINAS. EL POLIMERO SE FORMA MEDIANTE COPOLIMERIZACION RADICAL DE GLICOL DE POLIETILENO DERIVADO O GLICOL DE POLIPROPILENO BIS-TERMINAL, SUSTITUIDO CON UNA MITAD SELECCIONADA DEL GRUPO FORMADO POR ACRILOALQUILO, ACRILOARILO, ACRILAMIDOALQUILO Y ACRILAMIDOARILO, CON AMIDA ACRILICA, NITRILO O ESTER. CUANDO SE VA A USAR COMO UN SOPORTE SOLIDO O SUSTRATO DE INMOVILIZACION, EL POLIMERO INCORPORARA UN SEPARADOR, COMPRENDIENDO GRUPOS FUNCIONALES PARA LA UNION DE PEPTIDOS, PROTEINAS, NUCLEOTIDOS O SACARIDOS TALES COMO LOS SELECCIONADOS DEL GRUPO FORMADO POR AMINO, ALQUILAMINO, HIDROXI, CARBOXIL, MERCAPTO, SULFENO, SULFINO, SULFO Y DERIVADOS DE LOS MISMOS.
ES93903869T 1992-02-13 1993-02-12 Polimero que contiene polietilenglicol o polipropilenglicol. Expired - Lifetime ES2101300T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83527792A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
ES2101300T3 true ES2101300T3 (es) 1997-07-01

Family

ID=25269099

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93903869T Expired - Lifetime ES2101300T3 (es) 1992-02-13 1993-02-12 Polimero que contiene polietilenglicol o polipropilenglicol.

Country Status (11)

Country Link
US (1) US5352756A (es)
EP (1) EP0625996B1 (es)
JP (1) JPH07503744A (es)
AT (1) ATE152143T1 (es)
AU (1) AU660534B2 (es)
BR (1) BR9305894A (es)
CA (1) CA2129442C (es)
DE (1) DE69310148T2 (es)
DK (1) DK0625996T3 (es)
ES (1) ES2101300T3 (es)
WO (1) WO1993016118A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766897A (en) * 1990-06-21 1998-06-16 Incyte Pharmaceuticals, Inc. Cysteine-pegylated proteins
US5656707A (en) * 1995-06-16 1997-08-12 Regents Of The University Of Minnesota Highly cross-linked polymeric supports
DE19625397A1 (de) * 1996-06-25 1998-01-08 Deutsches Krebsforsch Verfahren zur Kombination von paralleler Oligonukleotidsynthese und Darstellung von Oligomer-Chips
DE19741356C2 (de) * 1997-09-19 2001-02-15 Cognis Deutschland Gmbh Verwendung von Glucoprotaminen
CA2345332A1 (en) * 1998-09-28 2000-04-06 Carlsberg A/S Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6722054B2 (en) 1998-11-12 2004-04-20 Atrix Laboratories, Inc. Process and delivery container for lyophilizing active agent
GB9926435D0 (en) * 1999-11-08 2000-01-12 Polymer Lab Ltd Method
US6566144B1 (en) * 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
CN1460023A (zh) * 2000-07-12 2003-12-03 格莱风治疗公司 聚合物修饰的生物活性合成趋化因子及其生产方法和用途
EP1315511A4 (en) * 2000-09-08 2005-10-19 Gryphon Therapeutics Inc SYNTHESIS PROTEINS STIMULATING ERYTHROPOYSIS
US7118737B2 (en) 2000-09-08 2006-10-10 Amylin Pharmaceuticals, Inc. Polymer-modified synthetic proteins
ATE316105T1 (de) * 2000-11-20 2006-02-15 Matrix Innovation Inc Herstellung amphiphiler fester träger für die peptidsynthese und die bioorganische und organische chemie
US6979530B2 (en) * 2001-05-21 2005-12-27 Applera Corporation Peptide conjugates and fluorescence detection methods for intracellular caspase assay
US20040077835A1 (en) * 2001-07-12 2004-04-22 Robin Offord Chemokine receptor modulators, production and use
WO2003018605A2 (en) * 2001-08-24 2003-03-06 University Of British Columbia Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases
WO2003031489A2 (en) * 2001-10-12 2003-04-17 Carlsberg A/S Matrix for solid-phase organic synthesis
AU2003303595A1 (en) * 2002-12-30 2004-07-29 Gryphon Therapeutics, Inc. Water-soluble thioester and selenoester compounds and methods for making and using the same
WO2005012277A1 (en) 2003-08-04 2005-02-10 Matrix Innovation Inc. New polyether based monomers and highly cross-linked amphiphile resins
EP2314320A2 (en) 2005-04-05 2011-04-27 Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. Method for shielding functional sites or epitopes on proteins
US7985783B2 (en) 2006-09-21 2011-07-26 The Regents Of The University Of California Aldehyde tags, uses thereof in site-specific protein modification
JP6208658B2 (ja) 2011-07-05 2017-10-04 バイオアシス テクノロジーズ インコーポレイテッド ｐ９７−抗体結合体および使用方法
US9932565B2 (en) 2012-07-31 2018-04-03 Bioasis Technologies, Inc. Dephosphorylated lysosomal storage disease proteins and methods of use thereof
KR20150083121A (ko) 2012-11-12 2015-07-16 레드우드 바이오사이언스 인코포레이티드 화합물, 및 컨쥬게이트의 제조방법
KR20150085064A (ko) 2012-11-16 2015-07-22 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 단백질 화학적 변형을 위한 피크테 스펭글러 결합
US9310374B2 (en) 2012-11-16 2016-04-12 Redwood Bioscience, Inc. Hydrazinyl-indole compounds and methods for producing a conjugate
CA2906003C (en) 2013-03-13 2021-07-06 Bioasis Technologies Inc. Fragments of p97 and uses thereof
AU2014312190A1 (en) 2013-08-28 2016-02-18 Bioasis Technologies Inc. CNS-targeted conjugates of antibodies
US9493413B2 (en) 2013-11-27 2016-11-15 Redwood Bioscience, Inc. Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
TWI725116B (zh) 2016-02-05 2021-04-21 愛爾蘭商托爾瑪國際有限公司 用於注射器陣列之開孔蓋板
WO2019133399A1 (en) 2017-12-26 2019-07-04 Becton, Dickinson And Company Deep ultraviolet-excitable water-solvated polymeric dyes
EP3775052B1 (en) 2018-03-30 2024-06-05 Becton, Dickinson and Company Water-soluble polymeric dyes having pendant chromophores
USD908916S1 (en) 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
US20220162336A1 (en) 2018-07-22 2022-05-26 Bioasis Technologies, Inc. Treatment of lymphatic metastases
US20210355468A1 (en) 2020-05-18 2021-11-18 Bioasis Technologies, Inc. Compositions and methods for treating lewy body dementia
US20210393787A1 (en) 2020-06-17 2021-12-23 Bioasis Technologies, Inc. Compositions and methods for treating frontotemporal dementia
EP4155349A1 (en) 2021-09-24 2023-03-29 Becton, Dickinson and Company Water-soluble yellow green absorbing dyes
WO2024007016A2 (en) 2022-07-01 2024-01-04 Beckman Coulter, Inc. Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
WO2024044327A1 (en) 2022-08-26 2024-02-29 Beckman Coulter, Inc. Dhnt monomers and polymer dyes with modified photophysical properties

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644038A (en) * 1985-09-30 1987-02-17 A. E. Staley Manufacturing Company Unsaturated poly (alpha-hydroxy acid) copolymers
JP2541614B2 (ja) * 1988-03-17 1996-10-09 鐘淵化学工業株式会社 硬化性組成物
US5087690A (en) * 1989-01-24 1992-02-11 Monsanto Hybrid amino resin compositions
US5130405A (en) * 1989-07-13 1992-07-14 Akzo N.V. Acid etch resistant coatings

Also Published As

Publication number Publication date
JPH07503744A (ja) 1995-04-20
EP0625996A1 (en) 1994-11-30
CA2129442A1 (en) 1993-08-14
US5352756A (en) 1994-10-04
DE69310148D1 (de) 1997-05-28
DE69310148T2 (de) 1997-07-31
CA2129442C (en) 2003-05-27
BR9305894A (pt) 1997-08-19
EP0625996B1 (en) 1997-04-23
AU3493493A (en) 1993-09-03
WO1993016118A1 (en) 1993-08-19
AU660534B2 (en) 1995-06-29
ATE152143T1 (de) 1997-05-15
DK0625996T3 (da) 1997-06-02

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