|
DE3023787A1
(de)
|
1980-06-25 |
1982-01-21 |
Studiengesellschaft Kohle mbH, 4330 Mülheim |
Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4659678A
(en)
|
1982-09-29 |
1987-04-21 |
Serono Diagnostics Limited |
Immunoassay of antigens
|
|
NZ207394A
(en)
|
1983-03-08 |
1987-03-06 |
Commw Serum Lab Commission |
Detecting or determining sequence of amino acids
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4727022A
(en)
|
1984-03-14 |
1988-02-23 |
Syntex (U.S.A.) Inc. |
Methods for modulating ligand-receptor interactions and their application
|
|
DE3586772T2
(de)
|
1984-07-24 |
1993-03-04 |
Coselco Mimotopes Pty Ltd |
Verfahren zur bestimmung von mimotopen.
|
|
EP0232262A4
(en)
|
1985-08-15 |
1989-09-19 |
Stauffer Chemical Co |
TRYPTOPHANE GENERATING MICROORGANISM.
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5756696A
(en)
|
1986-01-16 |
1998-05-26 |
Regents Of The University Of California |
Compositions for chromosome-specific staining
|
|
US5447841A
(en)
|
1986-01-16 |
1995-09-05 |
The Regents Of The Univ. Of California |
Methods for chromosome-specific staining
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US6121424A
(en)
|
1991-11-25 |
2000-09-19 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
EP0394827A1
(en)
|
1989-04-26 |
1990-10-31 |
F. Hoffmann-La Roche Ag |
Chimaeric CD4-immunoglobulin polypeptides
|
|
EP0452457B1
(en)
|
1989-11-03 |
1997-08-20 |
Vanderbilt University |
Method of in vivo delivery of functioning foreign genes
|
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DE4002897A1
(de)
|
1990-02-01 |
1991-08-08 |
Behringwerke Ag |
Herstellung und verwendung von genbanken synthetischer menschlicher antikoerper ("synthetische human-antikoerper-bibliotheken")
|
|
ES2225816T5
(es)
|
1990-02-01 |
2014-08-21 |
Siemens Healthcare Diagnostics Products Gmbh |
Producción y utilización de bancos de genes de anticuerpos humanos ("bibliotecas de anticuerpos humanos")
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
DK0464533T3
(da)
|
1990-06-28 |
1999-04-26 |
Gen Hospital Corp |
Fusionsproteiner med immunglobulindele, deres fremstilling og anvendelse
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5491224A
(en)
|
1990-09-20 |
1996-02-13 |
Bittner; Michael L. |
Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
US6710174B2
(en)
|
2001-09-13 |
2004-03-23 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of vascular endothelial growth factor receptor-1 expression
|
|
IL108367A0
(en)
|
1993-01-27 |
1994-04-12 |
Hektoen Inst For Medical Resea |
Antisense polynzcleotide inhibition of human growth factor-sensitive cancer cells
|
|
US6340674B1
(en)
|
1993-03-26 |
2002-01-22 |
Thomas Jefferson University |
Method of inhibiting the proliferation and causing the differentiation of cells with IGF-1 receptor antisense oligonucleotides
|
|
US5480971A
(en)
|
1993-06-17 |
1996-01-02 |
Houghten Pharmaceuticals, Inc. |
Peralkylated oligopeptide mixtures
|
|
DE69534347T2
(de)
|
1994-01-31 |
2006-05-24 |
Trustees Of Boston University, Boston |
Bibliotheken aus Polyklonalen Antikörpern
|
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
|
US5820873A
(en)
|
1994-09-30 |
1998-10-13 |
The University Of British Columbia |
Polyethylene glycol modified ceramide lipids and liposome uses thereof
|
|
US5753613A
(en)
|
1994-09-30 |
1998-05-19 |
Inex Pharmaceuticals Corporation |
Compositions for the introduction of polyanionic materials into cells
|
|
US5783683A
(en)
|
1995-01-10 |
1998-07-21 |
Genta Inc. |
Antisense oligonucleotides which reduce expression of the FGFRI gene
|
|
US5675063A
(en)
|
1995-02-28 |
1997-10-07 |
Loyola University Of Chicago |
Immortalized rabbit hybridoma fusion partner
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
US6395713B1
(en)
|
1997-07-23 |
2002-05-28 |
Ribozyme Pharmaceuticals, Inc. |
Compositions for the delivery of negatively charged molecules
|
|
US6617162B2
(en)
|
2001-12-18 |
2003-09-09 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of estrogen receptor alpha expression
|
|
CA2315256A1
(en)
|
1997-12-16 |
1999-06-24 |
Valentis, Inc. |
Needle-free injection of formulated nucleic acid molecules
|
|
US7198896B2
(en)
|
1998-09-04 |
2007-04-03 |
Cell Signaling Technology, Inc. |
Immunoaffinity isolation of modified peptides from complex mixtures
|
|
US6573043B1
(en)
|
1998-10-07 |
2003-06-03 |
Genentech, Inc. |
Tissue analysis and kits therefor
|
|
DE60040274D1
(de)
|
1999-03-10 |
2008-10-30 |
Phogen Ltd |
Verabreichung von nukleinsäuren und proteinen an zellen
|
|
US7662793B2
(en)
|
1999-06-18 |
2010-02-16 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from a Pol III promoter
|
|
US7829693B2
(en)
|
1999-11-24 |
2010-11-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
|
ES2336887T5
(es)
|
2000-03-30 |
2019-03-06 |
Whitehead Inst Biomedical Res |
Mediadores de interferencia por ARN específicos de secuencias de ARN
|
|
AU8843701A
(en)
|
2000-09-09 |
2002-03-22 |
Univ New York State Res Found |
Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof
|
|
CA2429814C
(en)
|
2000-12-01 |
2014-02-18 |
Thomas Tuschl |
Rna interference mediating small rna molecules
|
|
ME00502B
(me)
|
2001-01-05 |
2011-10-10 |
Amgen Fremont Inc |
Antitjela za insulinu sličan receptor faktora i rasta
|
|
US7313482B2
(en)
|
2001-05-17 |
2007-12-25 |
The Public Health Research Institute Of The City Of New York, Inc. |
Selection of target sites for antisense attack of RNA
|
|
US20030170891A1
(en)
|
2001-06-06 |
2003-09-11 |
Mcswiggen James A. |
RNA interference mediated inhibition of epidermal growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20040209832A1
(en)
|
2001-11-30 |
2004-10-21 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
CA2450793A1
(en)
|
2001-06-20 |
2002-12-27 |
Prochon Biotech Ltd. |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
WO2003016861A2
(en)
|
2001-08-14 |
2003-02-27 |
President And Fellows Of Harvard College |
Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
|
|
US20030219839A1
(en)
|
2001-09-20 |
2003-11-27 |
Katherine Bowdish |
Anti-PDGF antibodies and methods for producing engineered antibodies
|
|
US6734017B2
(en)
|
2001-09-28 |
2004-05-11 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of vascular endothelial growth factor receptor-2 expression
|
|
DE10230997A1
(de)
|
2001-10-26 |
2003-07-17 |
Ribopharma Ag |
Medikament zur Erhöhung der Wirksamkeit eines Rezeptor-vermittelt Apoptose in Tumorzellen auslösenden Arzneimittels
|
|
PL375064A1
(en)
|
2002-05-20 |
2005-11-14 |
Abgenix, Inc. |
Treatment of renal carcinoma using antibodies against the egfr
|
|
DK2314629T4
(da)
|
2002-07-18 |
2023-02-06 |
Merus Nv |
Rekombinant produktion af blandinger af antistoffer
|
|
US20040023390A1
(en)
|
2002-08-05 |
2004-02-05 |
Davidson Beverly L. |
SiRNA-mediated gene silencing with viral vectors
|
|
WO2004063355A2
(en)
*
|
2003-01-10 |
2004-07-29 |
Protein Design Labs, Inc. |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer
|
|
JP2007528201A
(ja)
|
2003-03-14 |
2007-10-11 |
ファルマシア・コーポレーション |
癌治療のためのｉｇｆ−ｉ受容体に対する抗体
|
|
US20050214301A1
(en)
|
2004-03-24 |
2005-09-29 |
Cell Signaling Technology, Inc. |
Antibodies specific for BCR-ABL fusion protein and uses thereof
|
|
WO2007084631A2
(en)
|
2006-01-20 |
2007-07-26 |
Cell Signaling Technology, Inc. |
Translocation and mutant ros kinase in human non-small cell lung carcinoma
|
|
US20120208824A1
(en)
*
|
2006-01-20 |
2012-08-16 |
Cell Signaling Technology, Inc. |
ROS Kinase in Lung Cancer
|
|
SG177225A1
(en)
*
|
2006-12-01 |
2012-01-30 |
Agency Science Tech & Res |
Cancer-related protein kinases
|
|
JP5769968B2
(ja)
|
2007-10-18 |
2015-08-26 |
セル・シグナリング・テクノロジー・インコーポレイテツド |
ヒト非小細胞肺癌における転座および変異ｒｏｓキナーゼ
|
|
EP3266795A1
(en)
*
|
2009-02-12 |
2018-01-10 |
Cell Signaling Technology, Inc. |
Method for detecting a fig-ros fusion polynucleotide
|
|
RU2014102935A
(ru)
*
|
2011-08-02 |
2015-09-10 |
Пфайзер Инк. |
Кризотиниб для применения в лечении рака
|