JP2019193640A5 - - Google Patents
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- Publication number
- JP2019193640A5 JP2019193640A5 JP2019110591A JP2019110591A JP2019193640A5 JP 2019193640 A5 JP2019193640 A5 JP 2019193640A5 JP 2019110591 A JP2019110591 A JP 2019110591A JP 2019110591 A JP2019110591 A JP 2019110591A JP 2019193640 A5 JP2019193640 A5 JP 2019193640A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- food
- acid sequence
- seq
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001413 amino acids Chemical group 0.000 claims 10
- 235000013305 food Nutrition 0.000 claims 9
- 102000004882 Lipase Human genes 0.000 claims 8
- 108090001060 Lipase Proteins 0.000 claims 8
- 239000004367 Lipase Substances 0.000 claims 8
- 235000019421 lipase Nutrition 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 229940024606 amino acid Drugs 0.000 claims 4
- 235000001014 amino acid Nutrition 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000019634 flavors Nutrition 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 claims 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 1
- 229960001230 asparagine Drugs 0.000 claims 1
- 235000009582 asparagine Nutrition 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 235000013365 dairy product Nutrition 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000013067 intermediate product Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 150000004666 short chain fatty acids Chemical class 0.000 claims 1
- 235000021391 short chain fatty acids Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013255419 | 2013-12-10 | ||
| JP2013255419 | 2013-12-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552440A Division JP6787668B2 (ja) | 2013-12-10 | 2014-12-08 | 改変型リパーゼ及びその用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019193640A JP2019193640A (ja) | 2019-11-07 |
| JP2019193640A5 true JP2019193640A5 (enExample) | 2020-06-25 |
Family
ID=53371138
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552440A Active JP6787668B2 (ja) | 2013-12-10 | 2014-12-08 | 改変型リパーゼ及びその用途 |
| JP2019110591A Pending JP2019193640A (ja) | 2013-12-10 | 2019-06-13 | 改変型リパーゼ及びその用途 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552440A Active JP6787668B2 (ja) | 2013-12-10 | 2014-12-08 | 改変型リパーゼ及びその用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10415023B2 (enExample) |
| EP (1) | EP3081644B1 (enExample) |
| JP (2) | JP6787668B2 (enExample) |
| CN (1) | CN105814199B (enExample) |
| DK (1) | DK3081644T3 (enExample) |
| WO (1) | WO2015087833A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10415023B2 (en) * | 2013-12-10 | 2019-09-17 | Amano Enzyme Inc. | Modified lipase and use thereof |
| WO2017115323A2 (en) | 2015-12-30 | 2017-07-06 | Dsm Ip Assets B.V. | Partial enzymatic hydrolysis of triacylglycerols |
| WO2017115322A2 (en) * | 2015-12-30 | 2017-07-06 | Dsm Ip Assets B.V. | Partial enzymatic hydrolysis of triacylglycerols |
| EP3469076B1 (en) * | 2016-06-10 | 2020-09-02 | DSM IP Assets B.V. | Mutant lipase and use thereof |
| JP7165136B2 (ja) * | 2017-09-01 | 2022-11-02 | 天野エンザイム株式会社 | 改変型リパーゼ及びその用途 |
| WO2019219904A2 (en) * | 2018-05-18 | 2019-11-21 | Dsm Ip Assets B.V. | Mutant lipase and use thereof |
| CN112574973A (zh) * | 2019-09-30 | 2021-03-30 | 东莞泛亚太生物科技有限公司 | 具提升耐热性的脂肪酶 |
| JP2023515570A (ja) * | 2020-02-28 | 2023-04-13 | セーホーエル．ハンセン アクティーゼルスカブ | リパーゼ、組成物、方法、及びその使用 |
| CN118956817A (zh) * | 2020-04-29 | 2024-11-15 | 上海奥博生物医药股份有限公司 | 脂肪酶突变体及其应用 |
| JPWO2022168954A1 (enExample) | 2021-02-04 | 2022-08-11 | ||
| EP4395565A1 (en) | 2021-09-01 | 2024-07-10 | Chr. Hansen A/S | Yarrowia lipolytica and its use for producing lipases specifically liberating short chain fatty acids |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3444282A1 (de) | 1984-12-05 | 1986-06-05 | Hoechst Ag, 6230 Frankfurt | Kaesearoma |
| US6375947B1 (en) | 1998-11-05 | 2002-04-23 | International Flavors & Fragrances Inc. | Recombinant kid pregastric esterase and methods for its production and use |
| JP4723087B2 (ja) | 1998-11-27 | 2011-07-13 | ノボザイムス アクティーゼルスカブ | 脂質分解酵素変異体 |
| EP1130100A1 (en) * | 2000-02-14 | 2001-09-05 | Unilever N.V. | Modified lipolytic enzymes and their use |
| CN1491278A (zh) | 2001-02-07 | 2004-04-21 | ŵά�Ź�˾ | 脂酶变体 |
| US7052879B2 (en) * | 2001-08-31 | 2006-05-30 | Academia Sinica | Recombinant Candida rugosa lipases |
| JP4604524B2 (ja) * | 2004-03-16 | 2011-01-05 | 味の素株式会社 | 変異型アルドラーゼ、並びにこれを用いた光学活性ｉｈｏｇ及び光学活性モナティンの製造方法 |
| WO2006047469A2 (en) * | 2004-10-21 | 2006-05-04 | Novozymes, Inc. | Polypeptides having lipase activity and polynucleotides encoding same |
| JP4915728B2 (ja) | 2005-10-12 | 2012-04-11 | 花王株式会社 | 組換え微生物 |
| JP5769142B2 (ja) | 2007-09-04 | 2015-08-26 | 独立行政法人酒類総合研究所 | ピヒア属酵母において異種タンパク質を高分泌させる方法 |
| CN101855342B (zh) * | 2007-09-13 | 2013-07-10 | 科德克希思公司 | 用于还原苯乙酮的酮还原酶多肽 |
| CA2716692A1 (en) * | 2008-02-29 | 2009-09-03 | Dsm Ip Assets B.V. | Lipases with high specificity towards short chain fatty acids and uses thereof |
| DK2406372T3 (da) * | 2009-03-10 | 2017-11-27 | Dsm Ip Assets Bv | Prægastrisk esterase og derivater deraf |
| US10415023B2 (en) * | 2013-12-10 | 2019-09-17 | Amano Enzyme Inc. | Modified lipase and use thereof |
-
2014
- 2014-12-08 US US15/102,324 patent/US10415023B2/en active Active
- 2014-12-08 EP EP14869024.1A patent/EP3081644B1/en active Active
- 2014-12-08 JP JP2015552440A patent/JP6787668B2/ja active Active
- 2014-12-08 WO PCT/JP2014/082415 patent/WO2015087833A1/ja not_active Ceased
- 2014-12-08 CN CN201480066933.9A patent/CN105814199B/zh active Active
- 2014-12-08 DK DK14869024.1T patent/DK3081644T3/en active
-
2019
- 2019-06-13 JP JP2019110591A patent/JP2019193640A/ja active Pending
- 2019-07-26 US US16/522,803 patent/US10870840B2/en active Active
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