JP2018530565A5 - - Google Patents
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- Publication number
- JP2018530565A5 JP2018530565A5 JP2018517847A JP2018517847A JP2018530565A5 JP 2018530565 A5 JP2018530565 A5 JP 2018530565A5 JP 2018517847 A JP2018517847 A JP 2018517847A JP 2018517847 A JP2018517847 A JP 2018517847A JP 2018530565 A5 JP2018530565 A5 JP 2018530565A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- ferric hydroxide
- carboxylate
- carboxylate ligand
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 39
- 239000003446 ligand Substances 0.000 claims 30
- -1 carboxylate ligand-modified ferric hydroxide Chemical class 0.000 claims 17
- 150000007942 carboxylates Chemical class 0.000 claims 16
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 15
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical class [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 claims 12
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 10
- 229940095064 tartrate Drugs 0.000 claims 10
- WNLRTRBMVRJNCN-UHFFFAOYSA-L adipate(2-) Chemical compound [O-]C(=O)CCCCC([O-])=O WNLRTRBMVRJNCN-UHFFFAOYSA-L 0.000 claims 8
- 239000000463 material Substances 0.000 claims 8
- 229910052742 iron Inorganic materials 0.000 claims 6
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims 5
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- 239000003125 aqueous solvent Substances 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 4
- 229910001447 ferric ion Inorganic materials 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 238000002156 mixing Methods 0.000 claims 4
- 125000004043 oxo group Chemical group O=* 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- 239000003826 tablet Substances 0.000 claims 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 239000000843 powder Substances 0.000 claims 3
- 238000006467 substitution reaction Methods 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000003513 alkali Substances 0.000 claims 2
- 150000001735 carboxylic acids Chemical class 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- 229960004887 ferric hydroxide Drugs 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 239000013589 supplement Substances 0.000 claims 2
- 208000030760 Anaemia of chronic disease Diseases 0.000 claims 1
- 206010022971 Iron Deficiencies Diseases 0.000 claims 1
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- 238000002441 X-ray diffraction Methods 0.000 claims 1
- 230000004931 aggregating effect Effects 0.000 claims 1
- 208000022400 anemia due to chronic disease Diseases 0.000 claims 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims 1
- 238000003801 milling Methods 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1517893.2A GB201517893D0 (en) | 2015-10-09 | 2015-10-09 | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
| GB1517893.2 | 2015-10-09 | ||
| PCT/EP2016/074022 WO2017060441A1 (en) | 2015-10-09 | 2016-10-07 | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids and related compositions and uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018530565A JP2018530565A (ja) | 2018-10-18 |
| JP2018530565A5 true JP2018530565A5 (enExample) | 2019-11-14 |
| JP7008624B2 JP7008624B2 (ja) | 2022-01-25 |
Family
ID=55130824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517847A Active JP7008624B2 (ja) | 2015-10-09 | 2016-10-07 | カルボキシレート配位子修飾水酸化第二鉄コロイドおよび関連組成物を生成するための方法ならびに使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10722459B2 (enExample) |
| EP (1) | EP3359519B1 (enExample) |
| JP (1) | JP7008624B2 (enExample) |
| CN (1) | CN108430964B (enExample) |
| AU (1) | AU2016333725B2 (enExample) |
| BR (1) | BR112018007098B1 (enExample) |
| CA (1) | CA3000589C (enExample) |
| DK (1) | DK3359519T3 (enExample) |
| EA (1) | EA035547B1 (enExample) |
| ES (1) | ES2824452T3 (enExample) |
| GB (1) | GB201517893D0 (enExample) |
| HU (1) | HUE051502T2 (enExample) |
| MX (1) | MX2018004113A (enExample) |
| PL (1) | PL3359519T3 (enExample) |
| PT (1) | PT3359519T (enExample) |
| SG (1) | SG11201802770WA (enExample) |
| SI (1) | SI3359519T1 (enExample) |
| WO (1) | WO2017060441A1 (enExample) |
| ZA (1) | ZA201802192B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11560339B2 (en) | 2019-05-30 | 2023-01-24 | Koch Agronomie Services, LLC | Micronutrient foliar solutions |
| GB202005054D0 (en) | 2020-04-06 | 2020-05-20 | Nemysis Ltd | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases |
| CN115196684B (zh) * | 2022-07-25 | 2024-10-01 | 武汉海斯普林科技发展有限公司 | 一种高活性高纯氢氧化铁、制备方法及在合成对甲基苯磺酸铁中的应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3076798A (en) | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
| US3821192A (en) | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
| CN1124757A (zh) * | 1994-12-31 | 1996-06-19 | 温固 | 速溶多羟基混合金属盐正电固溶胶制备方法 |
| CN1121349C (zh) * | 2001-10-30 | 2003-09-17 | 李国栋 | 一种无团聚氧化锌纳米粉体制造方法 |
| US7994217B2 (en) | 2002-05-02 | 2011-08-09 | Xanodyne Pharmaceuticals, Inc. | Prenatal multivitamin/multimineral supplement |
| GB0211500D0 (en) | 2002-05-18 | 2002-06-26 | Vitra Pharmaceuticals Ltd | Method of forming iron hydroxypyrone compounds |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US8093423B2 (en) | 2003-02-19 | 2012-01-10 | Globoasia, Llc | Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same |
| TWI335218B (en) | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
| US7964568B2 (en) | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| US7179939B2 (en) | 2004-03-16 | 2007-02-20 | Navinta Llc | Sodium ferric gluconate complexes and method of manufacture thereof |
| WO2005111052A1 (de) | 2004-05-17 | 2005-11-24 | Cilag Ag | Verfahren zur herstellung von eisen (iii) gluconatkomlex |
| ZA200702421B (en) | 2004-10-08 | 2008-09-25 | Unilever Plc | Iron complex for use in the treatment and/or prevention of nutritional disorders |
| GB0702270D0 (en) * | 2007-02-06 | 2007-03-14 | Medical Res Council | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
| EA019635B1 (ru) * | 2007-02-06 | 2014-05-30 | Медикал Ресёрч Каунсил | Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения |
| GB0814326D0 (en) * | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
| CN101691485B (zh) * | 2009-07-29 | 2012-03-28 | 西南石油大学 | 钻井液用抗高温两性离子聚合物降滤失剂及其制备方法 |
| CN103272553B (zh) * | 2013-05-16 | 2015-05-13 | 武汉大学 | 一种用于除去水体中砷的磁性纳米氧化铁吸附剂的制备方法 |
| CN103626807B (zh) * | 2013-11-20 | 2017-07-07 | 青岛国风药业股份有限公司 | 一种多糖铁复合物的制备方法及其质量检测方法 |
| CN103848989B (zh) * | 2014-03-20 | 2016-06-08 | 南京大学 | 一种镍锌铁氧体/聚苯胺复合材料的制备方法 |
| WO2015178451A1 (ja) | 2014-05-23 | 2015-11-26 | 戸田工業株式会社 | ヘマタイト粒子粉末の製造方法、該ヘマタイト粒子粉末を用いた塗料及び樹脂組成物 |
-
2015
- 2015-10-09 GB GBGB1517893.2A patent/GB201517893D0/en not_active Ceased
-
2016
- 2016-10-07 CN CN201680058940.3A patent/CN108430964B/zh active Active
- 2016-10-07 HU HUE16778044A patent/HUE051502T2/hu unknown
- 2016-10-07 SG SG11201802770WA patent/SG11201802770WA/en unknown
- 2016-10-07 BR BR112018007098-0A patent/BR112018007098B1/pt active IP Right Grant
- 2016-10-07 JP JP2018517847A patent/JP7008624B2/ja active Active
- 2016-10-07 ES ES16778044T patent/ES2824452T3/es active Active
- 2016-10-07 EA EA201890601A patent/EA035547B1/ru unknown
- 2016-10-07 PL PL16778044T patent/PL3359519T3/pl unknown
- 2016-10-07 MX MX2018004113A patent/MX2018004113A/es unknown
- 2016-10-07 DK DK16778044.4T patent/DK3359519T3/da active
- 2016-10-07 SI SI201630967T patent/SI3359519T1/sl unknown
- 2016-10-07 AU AU2016333725A patent/AU2016333725B2/en active Active
- 2016-10-07 PT PT167780444T patent/PT3359519T/pt unknown
- 2016-10-07 US US15/765,367 patent/US10722459B2/en active Active
- 2016-10-07 CA CA3000589A patent/CA3000589C/en active Active
- 2016-10-07 WO PCT/EP2016/074022 patent/WO2017060441A1/en not_active Ceased
- 2016-10-07 EP EP16778044.4A patent/EP3359519B1/en active Active
-
2018
- 2018-04-04 ZA ZA2018/02192A patent/ZA201802192B/en unknown
-
2020
- 2020-01-21 US US16/747,821 patent/US11684572B2/en active Active
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