JP2018524014A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018524014A5 JP2018524014A5 JP2018502674A JP2018502674A JP2018524014A5 JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5 JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotides
- polynucleotide
- length
- item
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195280P | 2015-07-21 | 2015-07-21 | |
| US62/195,280 | 2015-07-21 | ||
| PCT/US2016/043430 WO2017015513A1 (en) | 2015-07-21 | 2016-07-21 | Locked nucleic acids for capturing fusion genes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524014A JP2018524014A (ja) | 2018-08-30 |
| JP2018524014A5 true JP2018524014A5 (enExample) | 2019-09-05 |
| JP7074661B2 JP7074661B2 (ja) | 2022-05-25 |
Family
ID=57835293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502674A Active JP7074661B2 (ja) | 2015-07-21 | 2016-07-21 | 融合遺伝子を捕捉するためのロックド核酸 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20190071730A9 (enExample) |
| EP (2) | EP3828292A1 (enExample) |
| JP (1) | JP7074661B2 (enExample) |
| CN (1) | CN108138230B (enExample) |
| AU (1) | AU2016297096B2 (enExample) |
| CA (1) | CA2993019A1 (enExample) |
| ES (1) | ES2844852T3 (enExample) |
| WO (1) | WO2017015513A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3907297A1 (en) | 2011-04-15 | 2021-11-10 | The Johns Hopkins University | Safe sequencing system |
| US11525163B2 (en) | 2012-10-29 | 2022-12-13 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| ES2840003T3 (es) | 2016-09-30 | 2021-07-06 | Guardant Health Inc | Métodos para análisis multi-resolución de ácidos nucleicos libres de células |
| US20200165687A1 (en) * | 2017-06-27 | 2020-05-28 | The University Of Tokyo | Probe and method for detecting transcript resulting from fusion gene and/or exon skipping |
| SG11202001010UA (en) | 2017-08-07 | 2020-03-30 | Univ Johns Hopkins | Methods and materials for assessing and treating cancer |
| CN108642159B (zh) * | 2018-06-27 | 2022-07-01 | 上海宏滩生物科技有限公司 | 生物芯片检测系统 |
| CN113661249B (zh) | 2019-01-31 | 2025-07-01 | 夸登特健康公司 | 用于分离无细胞dna的组合物和方法 |
| JP2022521766A (ja) * | 2019-02-25 | 2022-04-12 | ツイスト バイオサイエンス コーポレーション | 次世代シーケンシングのための組成物および方法 |
| CN110195098A (zh) * | 2019-05-10 | 2019-09-03 | 广州安必平医药科技股份有限公司 | 用于检测braf相关融合基因的探针组、试剂盒及其应用 |
| US12173282B2 (en) | 2019-09-23 | 2024-12-24 | Twist Bioscience, Inc. | Antibodies that bind CD3 epsilon |
| CA3170345A1 (en) | 2020-02-14 | 2021-08-19 | The Johns Hopkins University | Methods and materials for assessing nucleic acids |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| CN111979307B (zh) * | 2020-08-31 | 2022-07-08 | 伯科生物科技有限公司 | 用于检测基因融合的靶向测序方法 |
| CN116240268B (zh) * | 2023-02-27 | 2024-04-26 | 北京大学口腔医学院 | 用于检测多个基因重排探针系统 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5482834A (en) * | 1982-05-17 | 1996-01-09 | Hahnemann University | Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells |
| US5200313A (en) * | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| WO2009000912A2 (en) * | 2007-06-27 | 2008-12-31 | Oslo Universitetssykehus Hf | Fusion gene microarray |
| CN101928767A (zh) * | 2009-06-29 | 2010-12-29 | 林新华 | 用于检测慢性粒细胞白血病bcr/abl融合基因的电化学dna生物传感器 |
| EP2494069B1 (en) * | 2009-10-30 | 2013-10-02 | Roche Diagniostics GmbH | Method for detecting balanced chromosomal aberrations in a genome |
| US20130059294A1 (en) * | 2010-05-16 | 2013-03-07 | Xiangdong Ren | Identification of polymorphic hepatitis b viruses and kras oncogene mutations and clinical use |
| CN103534359B (zh) * | 2011-03-14 | 2016-07-06 | 文塔纳医疗系统公司 | 分析染色体易位的方法及其系统 |
| US20140106986A1 (en) * | 2011-06-01 | 2014-04-17 | Medical Prognosis Institute A/S | Methods and devices for prognosis of cancer relapse |
| AU2011372509B2 (en) * | 2011-07-01 | 2017-02-09 | Htg Molecular Diagnostics, Inc. | Methods of detecting gene fusions |
| AU2013216904A1 (en) * | 2012-02-08 | 2014-08-28 | Insight Genetics, Inc. | Methods and compositions relating to fusions of ROS1 for diagnosing and treating cancer |
| EP2844773B1 (en) * | 2012-05-04 | 2017-08-16 | Boreal Genomics Corp. | Biomarker analysis using scodaphoresis |
| CN110872617A (zh) * | 2012-09-04 | 2020-03-10 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| ES2831148T3 (es) * | 2013-03-15 | 2021-06-07 | Univ Leland Stanford Junior | Identificación y uso de marcadores tumorales de ácido nucleico circulante |
| EP4439566A3 (en) | 2013-03-15 | 2024-12-04 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| CN105378110B (zh) * | 2013-04-17 | 2024-06-25 | 生命技术公司 | 与癌症相关的基因融合体和基因变异体 |
| ES2784450T3 (es) * | 2013-12-28 | 2020-09-25 | Guardant Health Inc | Métodos y sistemas para detectar variantes genéticas |
-
2016
- 2016-07-21 JP JP2018502674A patent/JP7074661B2/ja active Active
- 2016-07-21 WO PCT/US2016/043430 patent/WO2017015513A1/en not_active Ceased
- 2016-07-21 CA CA2993019A patent/CA2993019A1/en active Pending
- 2016-07-21 US US15/746,395 patent/US20190071730A9/en not_active Abandoned
- 2016-07-21 CN CN201680054945.9A patent/CN108138230B/zh active Active
- 2016-07-21 EP EP20206400.2A patent/EP3828292A1/en not_active Withdrawn
- 2016-07-21 AU AU2016297096A patent/AU2016297096B2/en active Active
- 2016-07-21 EP EP16828575.7A patent/EP3325667B1/en active Active
- 2016-07-21 ES ES16828575T patent/ES2844852T3/es active Active
-
2017
- 2017-02-13 US US15/431,393 patent/US20170226590A1/en not_active Abandoned
-
2022
- 2022-03-14 US US17/694,423 patent/US20220411877A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018524014A5 (enExample) | ||
| JP7514263B2 (ja) | 試料核酸にアダプターを付着する方法 | |
| EP3252174B1 (en) | Compositions, methods, systems and kits for target nucleic acid enrichment | |
| JP6684790B2 (ja) | シーケンスに基づく検出方法 | |
| CN106555226B (zh) | 一种构建高通量测序文库的方法和试剂盒 | |
| JP2018516569A (ja) | 次世代ゲノムウォーキングのための方法ならびに関連する組成物およびキット | |
| CN105734679B (zh) | 核酸靶序列捕获测序文库的制备方法 | |
| CN105936940B (zh) | 检测耳聋基因的核酸序列及其应用 | |
| US20200299764A1 (en) | System and method for transposase-mediated amplicon sequencing | |
| JP2020536525A (ja) | プローブ及びこれをハイスループットシーケンシングに適用するターゲット領域の濃縮方法 | |
| JP2016520326A (ja) | マルチプレックス配列決定のための分子バーコード化 | |
| WO2012000150A1 (zh) | Hla-a，b基因分型用pcr引物及其使用方法 | |
| CN103555846A (zh) | 一种基于液相分子杂交原理的高通量低成本snp分型方法 | |
| WO2018147438A1 (ja) | Ｈｌａ遺伝子のｐｃｒプライマーセット及びそれを用いたシークエンス法 | |
| CN105658811A (zh) | 利用核苷酸类似物和解旋酶恒温扩增dna分子的方法 | |
| CN101921860B (zh) | 44个snp位点多色荧光复合检测的方法及试剂盒 | |
| CN104350159A (zh) | 制备在利用核酸聚合酶来检测核酸时使用的高精度核酸的方法 | |
| US20160244849A1 (en) | Multiplex diagnostic assay for detecting salmonid pathogens | |
| WO2009036514A2 (en) | Method of amplifying nucleic acid | |
| CN106591442B (zh) | 用于y染色体微缺失检测的引物组合及试剂盒 | |
| CN113840923A (zh) | 用于核酸检测的方法、系统和设备 | |
| KR101282924B1 (ko) | 살모넬라의 동시 검출을 위한 ｐｃｒ 프라이머 | |
| EP3099812B1 (en) | Method and kit with internal amplification control | |
| CN106319079A (zh) | 一种检测22q11.2拷贝数缺失的方法 | |
| JP4491276B2 (ja) | 標的ｄｎａ配列において一塩基変異多型の存在を検出する方法及びキット |