JP2018524014A5 - - Google Patents

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Publication number
JP2018524014A5
JP2018524014A5 JP2018502674A JP2018502674A JP2018524014A5 JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5 JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5
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JP
Japan
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nucleotides
polynucleotide
length
item
probe
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JP2018502674A
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English (en)
Japanese (ja)
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JP7074661B2 (ja
JP2018524014A (ja
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Priority claimed from PCT/US2016/043430 external-priority patent/WO2017015513A1/en
Publication of JP2018524014A publication Critical patent/JP2018524014A/ja
Publication of JP2018524014A5 publication Critical patent/JP2018524014A5/ja
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JP2018502674A 2015-07-21 2016-07-21 融合遺伝子を捕捉するためのロックド核酸 Active JP7074661B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562195280P 2015-07-21 2015-07-21
US62/195,280 2015-07-21
PCT/US2016/043430 WO2017015513A1 (en) 2015-07-21 2016-07-21 Locked nucleic acids for capturing fusion genes

Publications (3)

Publication Number Publication Date
JP2018524014A JP2018524014A (ja) 2018-08-30
JP2018524014A5 true JP2018524014A5 (enExample) 2019-09-05
JP7074661B2 JP7074661B2 (ja) 2022-05-25

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ID=57835293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018502674A Active JP7074661B2 (ja) 2015-07-21 2016-07-21 融合遺伝子を捕捉するためのロックド核酸

Country Status (7)

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US (3) US20190071730A9 (enExample)
EP (2) EP3828292A1 (enExample)
JP (1) JP7074661B2 (enExample)
CN (1) CN108138230B (enExample)
AU (1) AU2016297096B2 (enExample)
ES (1) ES2844852T3 (enExample)
WO (1) WO2017015513A1 (enExample)

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ES2986436T3 (es) 2011-04-15 2024-11-11 Univ Johns Hopkins Sistema de secuenciación segura
ES2886507T5 (es) 2012-10-29 2024-11-15 Univ Johns Hopkins Prueba de Papanicolaou para cánceres de ovario y de endometrio
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
EP3461274B1 (en) 2016-09-30 2020-11-04 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
JPWO2019004080A1 (ja) * 2017-06-27 2020-04-23 国立大学法人 東京大学 融合遺伝子及び/又はエクソンスキッピングにより生ずる転写産物を検出するためのプローブ及び方法
CN111868260B (zh) 2017-08-07 2025-02-21 约翰斯霍普金斯大学 用于评估和治疗癌症的方法和材料
CN108642159B (zh) * 2018-06-27 2022-07-01 上海宏滩生物科技有限公司 生物芯片检测系统
WO2020160414A1 (en) 2019-01-31 2020-08-06 Guardant Health, Inc. Compositions and methods for isolating cell-free dna
CA3131514A1 (en) * 2019-02-25 2020-09-03 Twist Bioscience Corporation Compositions and methods for next generation sequencing
CN110195098A (zh) * 2019-05-10 2019-09-03 广州安必平医药科技股份有限公司 用于检测braf相关融合基因的探针组、试剂盒及其应用
JP2022548783A (ja) 2019-09-23 2022-11-21 ツイスト バイオサイエンス コーポレーション 単一ドメイン抗体のバリアント核酸ライブラリー
EP4103748A4 (en) 2020-02-14 2024-03-13 The Johns Hopkins University METHOD AND MATERIALS FOR ASSESSING NUCLEIC ACIDS
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
CN114958997B (zh) * 2020-08-31 2025-08-22 伯科生物科技有限公司 用于检测伴侣基因的方法
CN116240268B (zh) * 2023-02-27 2024-04-26 北京大学口腔医学院 用于检测多个基因重排探针系统

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US5482834A (en) * 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
WO2009000912A2 (en) * 2007-06-27 2008-12-31 Oslo Universitetssykehus Hf Fusion gene microarray
CN101928767A (zh) * 2009-06-29 2010-12-29 林新华 用于检测慢性粒细胞白血病bcr/abl融合基因的电化学dna生物传感器
WO2011050981A2 (en) 2009-10-30 2011-05-05 Roche Diagnostics Gmbh Method for detecting balanced chromosomal aberrations in a genome
US20130059294A1 (en) * 2010-05-16 2013-03-07 Xiangdong Ren Identification of polymorphic hepatitis b viruses and kras oncogene mutations and clinical use
US9562259B2 (en) * 2011-03-14 2017-02-07 Ventana Medical Systems, Inc. Method of analyzing chromosomal inversions
AU2012265177B2 (en) * 2011-06-01 2017-03-02 Medical Prognosis Institute A/S Methods and devices for prognosis of cancer relapse
CA3113672A1 (en) * 2011-07-01 2013-01-10 Htg Molecular Diagnostics, Inc. Methods of detecting gene fusions
WO2013119950A2 (en) * 2012-02-08 2013-08-15 Insight Genetics, Inc. Methods and compositions relating to fusions of ros1 for diagnosing and treating cancer
WO2013166444A2 (en) * 2012-05-04 2013-11-07 Boreal Genomics Corp. Biomarker analysis using scodaphoresis
CN104781421B (zh) 2012-09-04 2020-06-05 夸登特健康公司 检测稀有突变和拷贝数变异的系统和方法
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AU2014254394B2 (en) * 2013-04-17 2020-06-18 Life Technologies Corporation Gene fusions and gene variants associated with cancer
ES2660989T3 (es) 2013-12-28 2018-03-27 Guardant Health, Inc. Métodos y sistemas para detectar variantes genéticas

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