JP2018524014A5 - - Google Patents
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- JP2018524014A5 JP2018524014A5 JP2018502674A JP2018502674A JP2018524014A5 JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5 JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018502674 A JP2018502674 A JP 2018502674A JP 2018524014 A5 JP2018524014 A5 JP 2018524014A5
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- JP
- Japan
- Prior art keywords
- nucleotides
- polynucleotide
- length
- item
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195280P | 2015-07-21 | 2015-07-21 | |
| US62/195,280 | 2015-07-21 | ||
| PCT/US2016/043430 WO2017015513A1 (en) | 2015-07-21 | 2016-07-21 | Locked nucleic acids for capturing fusion genes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524014A JP2018524014A (ja) | 2018-08-30 |
| JP2018524014A5 true JP2018524014A5 (enExample) | 2019-09-05 |
| JP7074661B2 JP7074661B2 (ja) | 2022-05-25 |
Family
ID=57835293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502674A Active JP7074661B2 (ja) | 2015-07-21 | 2016-07-21 | 融合遺伝子を捕捉するためのロックド核酸 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20190071730A9 (enExample) |
| EP (2) | EP3325667B1 (enExample) |
| JP (1) | JP7074661B2 (enExample) |
| CN (1) | CN108138230B (enExample) |
| AU (1) | AU2016297096B2 (enExample) |
| ES (1) | ES2844852T3 (enExample) |
| WO (1) | WO2017015513A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110016499B (zh) | 2011-04-15 | 2023-11-14 | 约翰·霍普金斯大学 | 安全测序系统 |
| WO2014070462A1 (en) | 2012-10-29 | 2014-05-08 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| ES2840003T3 (es) | 2016-09-30 | 2021-07-06 | Guardant Health Inc | Métodos para análisis multi-resolución de ácidos nucleicos libres de células |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| EP3647420B1 (en) * | 2017-06-27 | 2023-08-23 | The University Of Tokyo | Probe and method for detecting transcript resulting from fusion gene and/or exon skipping |
| BR112020002555A2 (pt) | 2017-08-07 | 2020-08-11 | The Johns Hopkins University | métodos e materiais para avaliar e tratar câncer |
| CN108642159B (zh) * | 2018-06-27 | 2022-07-01 | 上海宏滩生物科技有限公司 | 生物芯片检测系统 |
| US11643693B2 (en) | 2019-01-31 | 2023-05-09 | Guardant Health, Inc. | Compositions and methods for isolating cell-free DNA |
| JP2022521766A (ja) * | 2019-02-25 | 2022-04-12 | ツイスト バイオサイエンス コーポレーション | 次世代シーケンシングのための組成物および方法 |
| CN110195098A (zh) * | 2019-05-10 | 2019-09-03 | 广州安必平医药科技股份有限公司 | 用于检测braf相关融合基因的探针组、试剂盒及其应用 |
| CN115023440B (zh) | 2019-09-23 | 2025-09-12 | 特韦斯特生物科学公司 | 结合CD3ε的抗体 |
| EP4103748A4 (en) | 2020-02-14 | 2024-03-13 | The Johns Hopkins University | METHOD AND MATERIALS FOR ASSESSING NUCLEIC ACIDS |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| CN114958997B (zh) * | 2020-08-31 | 2025-08-22 | 伯科生物科技有限公司 | 用于检测伴侣基因的方法 |
| CN116240268B (zh) * | 2023-02-27 | 2024-04-26 | 北京大学口腔医学院 | 用于检测多个基因重排探针系统 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5482834A (en) * | 1982-05-17 | 1996-01-09 | Hahnemann University | Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells |
| US5200313A (en) * | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| WO2009000912A2 (en) * | 2007-06-27 | 2008-12-31 | Oslo Universitetssykehus Hf | Fusion gene microarray |
| CN101928767A (zh) * | 2009-06-29 | 2010-12-29 | 林新华 | 用于检测慢性粒细胞白血病bcr/abl融合基因的电化学dna生物传感器 |
| WO2011050981A2 (en) * | 2009-10-30 | 2011-05-05 | Roche Diagnostics Gmbh | Method for detecting balanced chromosomal aberrations in a genome |
| CN102985562A (zh) * | 2010-05-16 | 2013-03-20 | 润尼生命科学公司 | 鉴别多态性乙肝病毒和kras致癌基因突变及其临床应用 |
| AU2012228424B2 (en) * | 2011-03-14 | 2015-05-07 | Ventana Medical Systems, Inc. | A method of analyzing chromosomal translocations and a system therefore |
| EP2714927B1 (en) * | 2011-06-01 | 2016-08-10 | Medical Prognosis Institute A/S | Methods and devices for prognosis of cancer relapse |
| US10294515B2 (en) * | 2011-07-01 | 2019-05-21 | Htg Molecular Diagnostics, Inc. | Methods of detecting gene fusions |
| CN104364391A (zh) * | 2012-02-08 | 2015-02-18 | 因赛特遗传学公司 | 用于诊断和治疗癌症的涉及ros1融合的方法和组合物 |
| WO2013166444A2 (en) * | 2012-05-04 | 2013-11-07 | Boreal Genomics Corp. | Biomarker analysis using scodaphoresis |
| KR102393608B1 (ko) | 2012-09-04 | 2022-05-03 | 가던트 헬쓰, 인크. | 희귀 돌연변이 및 카피수 변이를 검출하기 위한 시스템 및 방법 |
| EP4484572A3 (en) * | 2013-03-15 | 2025-02-19 | The Board of Trustees of the Leland Stanford Junior University | Identification and use of circulating nucleic acid tumor markers |
| HK1222684A1 (zh) | 2013-03-15 | 2017-07-07 | 夸登特健康公司 | 检测稀有突变和拷贝数变异的系统和方法 |
| US20140315199A1 (en) * | 2013-04-17 | 2014-10-23 | Life Technologies Corporation | Gene fusions and gene variants associated with cancer |
| ES2660989T3 (es) * | 2013-12-28 | 2018-03-27 | Guardant Health, Inc. | Métodos y sistemas para detectar variantes genéticas |
-
2016
- 2016-07-21 EP EP16828575.7A patent/EP3325667B1/en active Active
- 2016-07-21 EP EP20206400.2A patent/EP3828292A1/en not_active Withdrawn
- 2016-07-21 US US15/746,395 patent/US20190071730A9/en not_active Abandoned
- 2016-07-21 JP JP2018502674A patent/JP7074661B2/ja active Active
- 2016-07-21 ES ES16828575T patent/ES2844852T3/es active Active
- 2016-07-21 WO PCT/US2016/043430 patent/WO2017015513A1/en not_active Ceased
- 2016-07-21 CN CN201680054945.9A patent/CN108138230B/zh active Active
- 2016-07-21 AU AU2016297096A patent/AU2016297096B2/en active Active
-
2017
- 2017-02-13 US US15/431,393 patent/US20170226590A1/en not_active Abandoned
-
2022
- 2022-03-14 US US17/694,423 patent/US20220411877A1/en not_active Abandoned
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