AU2016297096B2 - Locked nucleic acids for capturing fusion genes - Google Patents

Locked nucleic acids for capturing fusion genes Download PDF

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Publication number
AU2016297096B2
AU2016297096B2 AU2016297096A AU2016297096A AU2016297096B2 AU 2016297096 B2 AU2016297096 B2 AU 2016297096B2 AU 2016297096 A AU2016297096 A AU 2016297096A AU 2016297096 A AU2016297096 A AU 2016297096A AU 2016297096 B2 AU2016297096 B2 AU 2016297096B2
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Australia
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nucleotides
length
polynucleotide
breakpoint
probe
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AU2016297096A
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AU2016297096A9 (en
AU2016297096A1 (en
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Stefanie Ann Ward Mortimer
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Guardant Health Inc
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Guardant Health Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2016297096A 2015-07-21 2016-07-21 Locked nucleic acids for capturing fusion genes Active AU2016297096B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562195280P 2015-07-21 2015-07-21
US62/195,280 2015-07-21
PCT/US2016/043430 WO2017015513A1 (en) 2015-07-21 2016-07-21 Locked nucleic acids for capturing fusion genes

Publications (3)

Publication Number Publication Date
AU2016297096A1 AU2016297096A1 (en) 2018-02-15
AU2016297096A9 AU2016297096A9 (en) 2019-07-25
AU2016297096B2 true AU2016297096B2 (en) 2021-03-18

Family

ID=57835293

Family Applications (1)

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AU2016297096A Active AU2016297096B2 (en) 2015-07-21 2016-07-21 Locked nucleic acids for capturing fusion genes

Country Status (7)

Country Link
US (3) US20190071730A9 (enExample)
EP (2) EP3325667B1 (enExample)
JP (1) JP7074661B2 (enExample)
CN (1) CN108138230B (enExample)
AU (1) AU2016297096B2 (enExample)
ES (1) ES2844852T3 (enExample)
WO (1) WO2017015513A1 (enExample)

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CN110016499B (zh) 2011-04-15 2023-11-14 约翰·霍普金斯大学 安全测序系统
WO2014070462A1 (en) 2012-10-29 2014-05-08 The Johns Hopkins University Papanicolaou test for ovarian and endometrial cancers
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
ES2840003T3 (es) 2016-09-30 2021-07-06 Guardant Health Inc Métodos para análisis multi-resolución de ácidos nucleicos libres de células
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
EP3647420B1 (en) * 2017-06-27 2023-08-23 The University Of Tokyo Probe and method for detecting transcript resulting from fusion gene and/or exon skipping
BR112020002555A2 (pt) 2017-08-07 2020-08-11 The Johns Hopkins University métodos e materiais para avaliar e tratar câncer
CN108642159B (zh) * 2018-06-27 2022-07-01 上海宏滩生物科技有限公司 生物芯片检测系统
US11643693B2 (en) 2019-01-31 2023-05-09 Guardant Health, Inc. Compositions and methods for isolating cell-free DNA
JP2022521766A (ja) * 2019-02-25 2022-04-12 ツイスト バイオサイエンス コーポレーション 次世代シーケンシングのための組成物および方法
CN110195098A (zh) * 2019-05-10 2019-09-03 广州安必平医药科技股份有限公司 用于检测braf相关融合基因的探针组、试剂盒及其应用
CN115023440B (zh) 2019-09-23 2025-09-12 特韦斯特生物科学公司 结合CD3ε的抗体
EP4103748A4 (en) 2020-02-14 2024-03-13 The Johns Hopkins University METHOD AND MATERIALS FOR ASSESSING NUCLEIC ACIDS
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
CN114958997B (zh) * 2020-08-31 2025-08-22 伯科生物科技有限公司 用于检测伴侣基因的方法
CN116240268B (zh) * 2023-02-27 2024-04-26 北京大学口腔医学院 用于检测多个基因重排探针系统

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US20100279890A1 (en) * 2007-06-27 2010-11-04 Oslo Universitetssykehus Hf Fusion gene microarray

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US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
CN101928767A (zh) * 2009-06-29 2010-12-29 林新华 用于检测慢性粒细胞白血病bcr/abl融合基因的电化学dna生物传感器
WO2011050981A2 (en) * 2009-10-30 2011-05-05 Roche Diagnostics Gmbh Method for detecting balanced chromosomal aberrations in a genome
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Also Published As

Publication number Publication date
CN108138230B (zh) 2023-03-10
US20180195131A1 (en) 2018-07-12
EP3828292A1 (en) 2021-06-02
EP3325667B1 (en) 2020-11-11
JP2018524014A (ja) 2018-08-30
CN108138230A (zh) 2018-06-08
US20220411877A1 (en) 2022-12-29
WO2017015513A9 (en) 2018-04-12
AU2016297096A9 (en) 2019-07-25
JP7074661B2 (ja) 2022-05-25
WO2017015513A1 (en) 2017-01-26
CA2993019A1 (en) 2017-01-26
EP3325667A4 (en) 2018-12-19
EP3325667A1 (en) 2018-05-30
ES2844852T3 (es) 2021-07-22
US20190071730A9 (en) 2019-03-07
AU2016297096A1 (en) 2018-02-15
US20170226590A1 (en) 2017-08-10

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