JP2018523484A5 - - Google Patents
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- Publication number
- JP2018523484A5 JP2018523484A5 JP2018509542A JP2018509542A JP2018523484A5 JP 2018523484 A5 JP2018523484 A5 JP 2018523484A5 JP 2018509542 A JP2018509542 A JP 2018509542A JP 2018509542 A JP2018509542 A JP 2018509542A JP 2018523484 A5 JP2018523484 A5 JP 2018523484A5
- Authority
- JP
- Japan
- Prior art keywords
- car
- cell
- nucleic acid
- acid sequence
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1514874.5 | 2015-08-20 | ||
| GBGB1514874.5A GB201514874D0 (en) | 2015-08-20 | 2015-08-20 | Cell |
| PCT/GB2016/052563 WO2017029511A1 (en) | 2015-08-20 | 2016-08-19 | Cell |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020194900A Division JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523484A JP2018523484A (ja) | 2018-08-23 |
| JP2018523484A5 true JP2018523484A5 (enExample) | 2019-07-25 |
| JP7395249B2 JP7395249B2 (ja) | 2023-12-11 |
Family
ID=54292002
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018509542A Active JP7395249B2 (ja) | 2015-08-20 | 2016-08-19 | 細胞 |
| JP2020194900A Withdrawn JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
| JP2023180246A Pending JP2023178386A (ja) | 2015-08-20 | 2023-10-19 | 細胞 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020194900A Withdrawn JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
| JP2023180246A Pending JP2023178386A (ja) | 2015-08-20 | 2023-10-19 | 細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11365262B2 (enExample) |
| EP (1) | EP3337501A1 (enExample) |
| JP (3) | JP7395249B2 (enExample) |
| CN (1) | CN108135984A (enExample) |
| AU (1) | AU2016308617A1 (enExample) |
| CA (1) | CA2995775A1 (enExample) |
| GB (1) | GB201514874D0 (enExample) |
| HK (1) | HK1250667A1 (enExample) |
| WO (1) | WO2017029511A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| WO2014117121A1 (en) | 2013-01-28 | 2014-07-31 | St. Jude Children's Research Hospital, Inc. | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| KR102211120B1 (ko) | 2014-05-15 | 2021-02-03 | 내셔널 유니버시티 오브 싱가포르 | 변형된 천연 살해 세포 및 그의 용도 |
| US12144850B2 (en) | 2016-04-08 | 2024-11-19 | Purdue Research Foundation | Methods and compositions for car T cell therapy |
| GB201620070D0 (en) * | 2016-11-28 | 2017-01-11 | Autolus Ltd | Signal transduction modifying protein |
| WO2018132506A1 (en) | 2017-01-10 | 2018-07-19 | The General Hospital Corporation | Chimeric antigen receptors based on alternative signal 1 domains |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| ES3010559T3 (en) | 2017-02-28 | 2025-04-03 | Endocyte Inc | Compositions and methods for car t cell therapy |
| EP3595721B1 (en) * | 2017-03-16 | 2025-07-09 | The General Hospital Corporation | Chimeric antigen receptors targeting cd37 |
| IL269553B2 (en) | 2017-03-27 | 2025-10-01 | Nat Univ Singapore | Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells |
| WO2018182511A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| WO2018201088A1 (en) | 2017-04-27 | 2018-11-01 | Washington University | Activation of natural cytotoxicity receptor 2 (ncr2) |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| EP3704150A1 (en) * | 2017-11-01 | 2020-09-09 | F. Hoffmann-La Roche AG | The compbody - a multivalent target binder |
| US20190192678A1 (en) * | 2017-12-18 | 2019-06-27 | Novather, Inc. | System and method for the treatment of disease using a hyperspecific modified protein system |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| GB201801831D0 (en) * | 2018-02-05 | 2018-03-21 | Autolus Ltd | Chimeric receptor |
| WO2019156795A1 (en) | 2018-02-06 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| CA3091674A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| SG11202008976YA (en) | 2018-04-02 | 2020-10-29 | Nat Univ Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| FI3856775T3 (fi) * | 2018-09-27 | 2024-12-04 | Autolus Ltd | Kimeerinen antigeenireseptori |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| WO2020180882A1 (en) | 2019-03-05 | 2020-09-10 | Nkarta, Inc. | Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| AU2020296197A1 (en) * | 2019-06-21 | 2022-01-20 | Shattuck Labs, Inc. | Chimeric protein expressing T-cells |
| EP3997129B1 (en) * | 2019-07-11 | 2025-11-26 | Valkyr, Inc. | System and methods relating to chimeric autoantibody receptors |
| CN112779223B (zh) * | 2019-11-08 | 2024-06-11 | 浙江煦顼技术有限公司 | 偶联嵌合抗原受体细胞及其用途 |
| KR20220163940A (ko) | 2020-02-04 | 2022-12-12 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 항-디니트로페놀 키메라 항원 수용체 |
| GB202008688D0 (en) * | 2020-06-09 | 2020-07-22 | Cancer Research Tech Ltd | Chimeric antigen receptor cell |
| JP2026507228A (ja) | 2023-03-03 | 2026-02-27 | アーセナル バイオサイエンシズ インコーポレイテッド | Ｐｓｍａ及びｃａ９を標的とするシステム |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2389443B1 (en) * | 2009-01-23 | 2018-11-14 | Roger Williams Hospital | Retroviral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| EP3594245A1 (en) | 2012-02-13 | 2020-01-15 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| EP2970426B1 (en) * | 2013-03-15 | 2019-08-28 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| MX377283B (es) * | 2013-11-21 | 2025-03-07 | Ucl Business Ltd | Célula t o nk que coexpresa un receptor antigénico quimérico (car). |
| CA2931684C (en) | 2013-12-19 | 2024-02-20 | Novartis Ag | Human mesothelin chimeric antigen receptors and uses thereof |
| EP3593812A3 (en) | 2014-03-15 | 2020-05-27 | Novartis AG | Treatment of cancer using chimeric antigen receptor |
| GB201513540D0 (en) | 2015-07-31 | 2015-09-16 | King S College London | Therapeutic agents |
-
2015
- 2015-08-20 GB GBGB1514874.5A patent/GB201514874D0/en not_active Ceased
-
2016
- 2016-08-19 JP JP2018509542A patent/JP7395249B2/ja active Active
- 2016-08-19 CN CN201680046855.5A patent/CN108135984A/zh active Pending
- 2016-08-19 CA CA2995775A patent/CA2995775A1/en not_active Abandoned
- 2016-08-19 HK HK18110271.9A patent/HK1250667A1/zh unknown
- 2016-08-19 AU AU2016308617A patent/AU2016308617A1/en not_active Abandoned
- 2016-08-19 US US15/753,505 patent/US11365262B2/en active Active
- 2016-08-19 EP EP16756757.7A patent/EP3337501A1/en active Pending
- 2016-08-19 WO PCT/GB2016/052563 patent/WO2017029511A1/en not_active Ceased
-
2020
- 2020-11-25 JP JP2020194900A patent/JP2021027841A/ja not_active Withdrawn
-
2023
- 2023-10-19 JP JP2023180246A patent/JP2023178386A/ja active Pending
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