JP2018522062A5 - - Google Patents
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- Publication number
- JP2018522062A5 JP2018522062A5 JP2018513736A JP2018513736A JP2018522062A5 JP 2018522062 A5 JP2018522062 A5 JP 2018522062A5 JP 2018513736 A JP2018513736 A JP 2018513736A JP 2018513736 A JP2018513736 A JP 2018513736A JP 2018522062 A5 JP2018522062 A5 JP 2018522062A5
- Authority
- JP
- Japan
- Prior art keywords
- methylpyridin
- amine
- methyl
- benzyl
- naphthyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021089708A JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562166305P | 2015-05-26 | 2015-05-26 | |
| US62/166,305 | 2015-05-26 | ||
| PCT/US2016/034245 WO2016191525A1 (en) | 2015-05-26 | 2016-05-26 | Tumor biomarkers and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021089708A Division JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018522062A JP2018522062A (ja) | 2018-08-09 |
| JP2018522062A5 true JP2018522062A5 (enExample) | 2019-04-18 |
Family
ID=57394192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513736A Pending JP2018522062A (ja) | 2015-05-26 | 2016-05-26 | 腫瘍バイオマーカー及びその使用 |
| JP2021089708A Pending JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021089708A Pending JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20180112273A1 (enExample) |
| EP (1) | EP3302479A4 (enExample) |
| JP (2) | JP2018522062A (enExample) |
| KR (1) | KR20180010198A (enExample) |
| CN (1) | CN107708699A (enExample) |
| AU (1) | AU2016267142B2 (enExample) |
| CA (1) | CA2985813A1 (enExample) |
| HK (1) | HK1251171A1 (enExample) |
| WO (1) | WO2016191525A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105142641A (zh) | 2013-03-12 | 2015-12-09 | 广州源生医药科技有限公司 | 用于治疗癌症的化合物 |
| JP2019522658A (ja) * | 2016-06-22 | 2019-08-15 | ノバルティス アーゲー | 線維症の治療に使用するためのＷｎｔ阻害剤 |
| JP7419068B2 (ja) * | 2016-12-21 | 2024-01-22 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 悪性腫瘍を特定するためのキット及びその使用 |
| CN107441045B (zh) | 2017-07-21 | 2018-10-19 | 广州源生医药科技有限公司 | 用于递送Wnt信号通路抑制剂的脂质体制剂及其制备方法 |
| CN108685923A (zh) * | 2018-06-07 | 2018-10-23 | 广州源生医药科技有限公司 | Wnt信号通路抑制剂在治疗LGR5阳性癌症中的应用 |
| EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA103918C2 (en) * | 2009-03-02 | 2013-12-10 | Айерем Элелси | N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators |
| UY33469A (es) * | 2010-06-29 | 2012-01-31 | Irm Llc Y Novartis Ag | Composiciones y metodos para modular la via de señalizacion de wnt |
| CN102558173B (zh) * | 2010-12-31 | 2015-05-20 | 广州源生医药科技有限公司 | 抑制wnt信号传导的化合物、组合物及其应用 |
| MX366804B (es) * | 2012-02-11 | 2019-07-25 | Genentech Inc | Translocaciones de la r-espondina y sus metodos de uso. |
| ES2797533T3 (es) * | 2012-02-28 | 2020-12-02 | Novartis Ag | Selección de pacientes con cáncer para la administración de inhibidores de la señalización Wnt utilizando el estado mutacional de Rnf43 |
| CN105142641A (zh) * | 2013-03-12 | 2015-12-09 | 广州源生医药科技有限公司 | 用于治疗癌症的化合物 |
| CN105744954B (zh) * | 2013-10-18 | 2021-03-05 | 豪夫迈·罗氏有限公司 | 抗rspo2和/或抗rspo3抗体及其用途 |
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2016
- 2016-05-26 CN CN201680029836.1A patent/CN107708699A/zh active Pending
- 2016-05-26 AU AU2016267142A patent/AU2016267142B2/en not_active Ceased
- 2016-05-26 WO PCT/US2016/034245 patent/WO2016191525A1/en not_active Ceased
- 2016-05-26 EP EP16800691.4A patent/EP3302479A4/en not_active Withdrawn
- 2016-05-26 HK HK18110677.9A patent/HK1251171A1/zh unknown
- 2016-05-26 KR KR1020177033956A patent/KR20180010198A/ko not_active Abandoned
- 2016-05-26 JP JP2018513736A patent/JP2018522062A/ja active Pending
- 2016-05-26 CA CA2985813A patent/CA2985813A1/en not_active Abandoned
- 2016-05-26 US US15/575,780 patent/US20180112273A1/en not_active Abandoned
-
2020
- 2020-11-09 US US17/092,653 patent/US20210054466A1/en not_active Abandoned
-
2021
- 2021-05-28 JP JP2021089708A patent/JP2021130694A/ja active Pending