JP2018522062A5 - - Google Patents
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- Publication number
- JP2018522062A5 JP2018522062A5 JP2018513736A JP2018513736A JP2018522062A5 JP 2018522062 A5 JP2018522062 A5 JP 2018522062A5 JP 2018513736 A JP2018513736 A JP 2018513736A JP 2018513736 A JP2018513736 A JP 2018513736A JP 2018522062 A5 JP2018522062 A5 JP 2018522062A5
- Authority
- JP
- Japan
- Prior art keywords
- methylpyridin
- amine
- methyl
- benzyl
- naphthyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021089708A JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562166305P | 2015-05-26 | 2015-05-26 | |
| US62/166,305 | 2015-05-26 | ||
| PCT/US2016/034245 WO2016191525A1 (en) | 2015-05-26 | 2016-05-26 | Tumor biomarkers and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021089708A Division JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018522062A JP2018522062A (ja) | 2018-08-09 |
| JP2018522062A5 true JP2018522062A5 (enExample) | 2019-04-18 |
Family
ID=57394192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513736A Pending JP2018522062A (ja) | 2015-05-26 | 2016-05-26 | 腫瘍バイオマーカー及びその使用 |
| JP2021089708A Pending JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021089708A Pending JP2021130694A (ja) | 2015-05-26 | 2021-05-28 | 腫瘍バイオマーカー及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20180112273A1 (enExample) |
| EP (1) | EP3302479A4 (enExample) |
| JP (2) | JP2018522062A (enExample) |
| KR (1) | KR20180010198A (enExample) |
| CN (1) | CN107708699A (enExample) |
| AU (1) | AU2016267142B2 (enExample) |
| CA (1) | CA2985813A1 (enExample) |
| HK (1) | HK1251171A1 (enExample) |
| WO (1) | WO2016191525A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016518328A (ja) | 2013-03-12 | 2016-06-23 | キュアジェニックス インコーポレイテッド | 癌治療のための化合物 |
| US20200306244A1 (en) * | 2016-06-22 | 2020-10-01 | Novartis Ag | Wnt inhibitors for use in the treatment of fibrosis |
| JP7419068B2 (ja) * | 2016-12-21 | 2024-01-22 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 悪性腫瘍を特定するためのキット及びその使用 |
| CN107441045B (zh) | 2017-07-21 | 2018-10-19 | 广州源生医药科技有限公司 | 用于递送Wnt信号通路抑制剂的脂质体制剂及其制备方法 |
| CN108685923A (zh) * | 2018-06-07 | 2018-10-23 | 广州源生医药科技有限公司 | Wnt信号通路抑制剂在治疗LGR5阳性癌症中的应用 |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA103918C2 (en) * | 2009-03-02 | 2013-12-10 | Айерем Элелси | N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators |
| UY33469A (es) * | 2010-06-29 | 2012-01-31 | Irm Llc Y Novartis Ag | Composiciones y metodos para modular la via de señalizacion de wnt |
| CN102558173B (zh) * | 2010-12-31 | 2015-05-20 | 广州源生医药科技有限公司 | 抑制wnt信号传导的化合物、组合物及其应用 |
| BR112014019741A2 (pt) * | 2012-02-11 | 2020-12-22 | Genentech, Inc | Usos de um antagonista da via wnt, uso de uma terapia anticâncer, método de identificação de um indivíduo com câncer, métodos para prever, método de inibição da proliferação de uma célula de câncer, uso de um antagonista da translocação de r-spondina e antagonista da translocação de r-spondina isolado |
| BR112014020233A2 (pt) * | 2012-02-28 | 2017-07-04 | Irm Llc | seleção de paciente com câncer para administração de inibidores sinalizantes wnt usando status de mutação rnf43 |
| JP2016518328A (ja) * | 2013-03-12 | 2016-06-23 | キュアジェニックス インコーポレイテッド | 癌治療のための化合物 |
| US20150147333A1 (en) * | 2013-10-18 | 2015-05-28 | Genentech, Inc. | Anti-rspo antibodies and methods of use |
-
2016
- 2016-05-26 WO PCT/US2016/034245 patent/WO2016191525A1/en not_active Ceased
- 2016-05-26 HK HK18110677.9A patent/HK1251171A1/zh unknown
- 2016-05-26 CA CA2985813A patent/CA2985813A1/en not_active Abandoned
- 2016-05-26 JP JP2018513736A patent/JP2018522062A/ja active Pending
- 2016-05-26 CN CN201680029836.1A patent/CN107708699A/zh active Pending
- 2016-05-26 EP EP16800691.4A patent/EP3302479A4/en not_active Withdrawn
- 2016-05-26 AU AU2016267142A patent/AU2016267142B2/en not_active Ceased
- 2016-05-26 US US15/575,780 patent/US20180112273A1/en not_active Abandoned
- 2016-05-26 KR KR1020177033956A patent/KR20180010198A/ko not_active Abandoned
-
2020
- 2020-11-09 US US17/092,653 patent/US20210054466A1/en not_active Abandoned
-
2021
- 2021-05-28 JP JP2021089708A patent/JP2021130694A/ja active Pending
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