JP2013515032A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013515032A5 JP2013515032A5 JP2012545276A JP2012545276A JP2013515032A5 JP 2013515032 A5 JP2013515032 A5 JP 2013515032A5 JP 2012545276 A JP2012545276 A JP 2012545276A JP 2012545276 A JP2012545276 A JP 2012545276A JP 2013515032 A5 JP2013515032 A5 JP 2013515032A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridin
- pyrazolo
- yloxy
- acetamide
- ring system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2664DE2009 | 2009-12-21 | ||
| IN2664/DEL/2009 | 2009-12-21 | ||
| PCT/EP2010/070260 WO2011076744A1 (en) | 2009-12-21 | 2010-12-20 | Disubstituted heteroaryl-fused pyridines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515032A JP2013515032A (ja) | 2013-05-02 |
| JP2013515032A5 true JP2013515032A5 (enExample) | 2014-01-30 |
Family
ID=43640661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545276A Pending JP2013515032A (ja) | 2009-12-21 | 2010-12-20 | 二置換ヘテロアリール縮合ピリジン類 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8742106B2 (enExample) |
| EP (1) | EP2516437B1 (enExample) |
| JP (1) | JP2013515032A (enExample) |
| CN (1) | CN102762560A (enExample) |
| ES (1) | ES2460915T3 (enExample) |
| WO (1) | WO2011076744A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
| EP2811997B1 (en) | 2012-02-07 | 2018-04-11 | Eolas Therapeutics Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
| BR102012024778A2 (pt) | 2012-09-28 | 2014-08-19 | Cristalia Prod Quimicos Farm | Compostos heteroaromáticos; processo para preparar os compostos, composições farmacêuticas, usos e método de tratamento para as dores aguda e crônica |
| WO2016025669A1 (en) | 2014-08-13 | 2016-02-18 | Eolas Therapeutics, Inc. | Difluoropyrrolidines as orexin receptor modulators |
| HUE055662T2 (hu) | 2014-12-29 | 2021-12-28 | Us Health | Laktát-dehidrogenáz kismolekulás inhibitorai és alkalmazási eljárásai |
| CN105541719B (zh) * | 2016-02-03 | 2018-06-29 | 安徽工业大学 | 一种以乳清酸为原料制备5-氨基-1,2二氢吡唑-3-酮的方法 |
| PL3414241T3 (pl) | 2016-02-12 | 2022-10-03 | Astrazeneca Ab | Piperydyny podstawione halo jako modulatory receptora oreksyny |
| WO2018054832A1 (en) | 2016-09-22 | 2018-03-29 | Bayer Cropscience Aktiengesellschaft | Novel triazole derivatives |
| EP3515906A1 (en) | 2016-09-22 | 2019-07-31 | Bayer CropScience Aktiengesellschaft | Novel triazole derivatives and their use as fungicides |
| BR112019006441A2 (pt) | 2016-09-29 | 2019-06-25 | Bayer Ag | derivados de 5-imidazol metil dioxolano substituídos como fungicidas |
| CN109982999A (zh) | 2016-09-29 | 2019-07-05 | 拜耳作物科学股份公司 | 新的5-取代的咪唑基甲基衍生物 |
| JP2020506950A (ja) | 2017-02-08 | 2020-03-05 | バイエル アクチェンゲゼルシャフトＢａｙｅｒ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | トリアゾールチオン誘導体 |
| WO2018145932A1 (en) | 2017-02-08 | 2018-08-16 | Bayer Cropscience Aktiengesellschaft | Triazole derivatives and their use as fungicides |
| EP3580218A1 (en) | 2017-02-08 | 2019-12-18 | Bayer CropScience Aktiengesellschaft | Novel triazole derivatives |
| JP2020507579A (ja) | 2017-02-10 | 2020-03-12 | バイエル アクチェンゲゼルシャフトＢａｙｅｒ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | １−（フェノキシ−ピリジニル）−２−（１，２，４−トリアゾール−１−イル）−エタノール誘導体を含む有害微生物を制御するための組成物 |
| WO2020020816A1 (en) | 2018-07-26 | 2020-01-30 | Bayer Aktiengesellschaft | Novel triazole derivatives |
| US20210395185A1 (en) * | 2018-10-18 | 2021-12-23 | Boehringer Ingelheim International Gmbh | Scalable synthesis of optically active 1-cyclopropylalkyl-1-amines |
| MX2023005073A (es) * | 2020-11-02 | 2023-05-16 | Merck Sharp & Dohme Llc | Agonistas macrociclicos de los receptores de urea orexina. |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2232038A1 (de) | 1972-06-30 | 1974-01-10 | Hoechst Ag | 3-amino-1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine, ihre herstellung und verwendung |
| PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| WO2001098301A1 (en) * | 2000-06-20 | 2001-12-27 | Japan Tobacco Inc. | Pyrazolopyridine compounds and use thereof as drugs |
| US6962926B2 (en) | 2001-01-31 | 2005-11-08 | Telik, Inc. | Antagonist of MCP-1 function, and compositions and methods of use thereof |
| US6670364B2 (en) | 2001-01-31 | 2003-12-30 | Telik, Inc. | Antagonists of MCP-1 function and methods of use thereof |
| US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| US7601876B2 (en) * | 2002-05-31 | 2009-10-13 | Proteotech, Inc. | Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis |
| JP2007524596A (ja) | 2003-02-28 | 2007-08-30 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | 共結晶医薬組成物 |
| DE102004061288A1 (de) | 2004-12-14 | 2006-06-29 | Schering Ag | 3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel |
| AR057455A1 (es) | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| EP1764099A3 (en) | 2005-09-17 | 2007-05-09 | Speedel Experimenta AG | Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV |
| JP2007099640A (ja) | 2005-09-30 | 2007-04-19 | Tsumura & Co | 含窒素複素環化合物、その製造方法およびそれを用いた医薬組成物 |
| CA2647077A1 (en) | 2006-04-26 | 2007-11-01 | Actelion Pharmaceuticals Ltd | Pyrazolo-tetrahydro pyridine derivatives as orexin receptor antagonists |
| EP1870410A1 (en) | 2006-06-13 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| TW200815438A (en) | 2006-06-13 | 2008-04-01 | Bayer Schering Pharma Ag | Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| GB0617161D0 (en) | 2006-08-31 | 2006-10-11 | Vernalis R&D Ltd | Enzyme inhibitors |
| EA201070091A1 (ru) | 2007-07-03 | 2010-06-30 | Глэксо Груп Лимитед | Производные пиперидина, пригодные в качестве антагонистов рецептора орексина |
-
2010
- 2010-12-20 WO PCT/EP2010/070260 patent/WO2011076744A1/en not_active Ceased
- 2010-12-20 US US13/517,115 patent/US8742106B2/en not_active Expired - Fee Related
- 2010-12-20 EP EP10805785.2A patent/EP2516437B1/en not_active Not-in-force
- 2010-12-20 CN CN2010800643114A patent/CN102762560A/zh active Pending
- 2010-12-20 ES ES10805785.2T patent/ES2460915T3/es active Active
- 2010-12-20 JP JP2012545276A patent/JP2013515032A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013515032A5 (enExample) | ||
| RU2417994C2 (ru) | Производные пиразина, полезные в качестве антагонистов аденозинового рецептора | |
| JP2013515033A5 (enExample) | ||
| JP5847087B2 (ja) | オレキシン受容体調節因子としての縮合複素環式化合物 | |
| JP5759470B2 (ja) | オレキシン受容体調節因子としての二置換オクタヒドロピロロ［３，４−ｃ］ピロール | |
| RU2326881C2 (ru) | Конденсированные производные азолпиримидина, обладающие свойствами ингибитора фосфатидилинозитол-3-киназы (pi3k) | |
| JP5852099B2 (ja) | ある種のアミノ−ピリミジン、その組成物、及びそれを用いるための方法 | |
| AU2015270118C1 (en) | Pyrazole compounds and their use as T-type calcium channel blockers | |
| JP2013519724A5 (enExample) | ||
| JP2013520407A5 (enExample) | ||
| RU2478639C2 (ru) | Трициклические спиро-производные в качестве модуляторов crth2 | |
| EA015034B1 (ru) | 2-анилин-4-арилзамещенные тиазольные производные | |
| JP2009519967A5 (enExample) | ||
| JP2006503010A5 (enExample) | ||
| AU2013273222A1 (en) | Benzimidazole-proline derivatives | |
| CN103002897A (zh) | 特定氨基-哒嗪类，与其组合物，及其使用方法 | |
| JP2013515032A (ja) | 二置換ヘテロアリール縮合ピリジン類 | |
| AU2009288399A1 (en) | Hedgehog pathway modulators | |
| WO2012017020A1 (en) | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides as inhibitors of plasma kallikrein | |
| JP2012525431A5 (enExample) | ||
| DE10356579A1 (de) | Aminderivate | |
| JP2016523911A5 (enExample) | ||
| JP2014511885A5 (enExample) | ||
| JP2013515033A (ja) | オレキシン受容体アンタゴニストとしてのジアザ−スピロ［５．５］ウンデカン類 | |
| RU2012139828A (ru) | Производные пиразолопиперидина в качестве ингибиторов nadph-оксидазы |