JP2013515032A5 - - Google Patents
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- Publication number
- JP2013515032A5 JP2013515032A5 JP2012545276A JP2012545276A JP2013515032A5 JP 2013515032 A5 JP2013515032 A5 JP 2013515032A5 JP 2012545276 A JP2012545276 A JP 2012545276A JP 2012545276 A JP2012545276 A JP 2012545276A JP 2013515032 A5 JP2013515032 A5 JP 2013515032A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridin
- pyrazolo
- yloxy
- acetamide
- ring system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2664DE2009 | 2009-12-21 | ||
| IN2664/DEL/2009 | 2009-12-21 | ||
| PCT/EP2010/070260 WO2011076744A1 (en) | 2009-12-21 | 2010-12-20 | Disubstituted heteroaryl-fused pyridines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515032A JP2013515032A (ja) | 2013-05-02 |
| JP2013515032A5 true JP2013515032A5 (enExample) | 2014-01-30 |
Family
ID=43640661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545276A Pending JP2013515032A (ja) | 2009-12-21 | 2010-12-20 | 二置換ヘテロアリール縮合ピリジン類 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8742106B2 (enExample) |
| EP (1) | EP2516437B1 (enExample) |
| JP (1) | JP2013515032A (enExample) |
| CN (1) | CN102762560A (enExample) |
| ES (1) | ES2460915T3 (enExample) |
| WO (1) | WO2011076744A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104220065A (zh) | 2012-02-07 | 2014-12-17 | Eolas治疗公司 | 取代的脯氨酸/哌啶用作食欲素受体拮抗剂 |
| US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
| BR102012024778A2 (pt) | 2012-09-28 | 2014-08-19 | Cristalia Prod Quimicos Farm | Compostos heteroaromáticos; processo para preparar os compostos, composições farmacêuticas, usos e método de tratamento para as dores aguda e crônica |
| US10221170B2 (en) | 2014-08-13 | 2019-03-05 | Eolas Therapeutics, Inc. | Difluoropyrrolidines as orexin receptor modulators |
| EP3954685B1 (en) | 2014-12-29 | 2025-08-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Small molecule inhibitors of lactate dehydrogenase and methods of use thereof |
| CN105541719B (zh) * | 2016-02-03 | 2018-06-29 | 安徽工业大学 | 一种以乳清酸为原料制备5-氨基-1,2二氢吡唑-3-酮的方法 |
| SMT202200323T1 (it) | 2016-02-12 | 2022-09-14 | Astrazeneca Ab | Piperidine alo-sostituite come modulatori del recettore di oressina |
| WO2018054832A1 (en) | 2016-09-22 | 2018-03-29 | Bayer Cropscience Aktiengesellschaft | Novel triazole derivatives |
| EP3515906A1 (en) | 2016-09-22 | 2019-07-31 | Bayer CropScience Aktiengesellschaft | Novel triazole derivatives and their use as fungicides |
| US20200029563A1 (en) | 2016-09-29 | 2020-01-30 | Bayer Cropscience Aktiengesellschaft | Novel 5-substituted imidazolylmethyldioxolane derivatives |
| CA3038407A1 (en) | 2016-09-29 | 2018-04-05 | Bayer Cropscience Aktiengesellschaft | Novel 5-substituted imidazolylmethyl derivatives |
| US20200017467A1 (en) | 2017-02-08 | 2020-01-16 | Bayer Cropscience Aktiengesellschaft | Novel triazole derivatives |
| EP3580217A1 (en) | 2017-02-08 | 2019-12-18 | Bayer Aktiengesellschaft | Triazolethione derivatives |
| EP3580218A1 (en) | 2017-02-08 | 2019-12-18 | Bayer CropScience Aktiengesellschaft | Novel triazole derivatives |
| KR20190115449A (ko) | 2017-02-10 | 2019-10-11 | 바이엘 악티엔게젤샤프트 | 1-(페녹시-피리디닐)-2-(1,2,4-트리아졸-1-일)-에탄올 유도체를 포함하는 유해 미생물을 방제하기 위한 조성물 |
| WO2020020816A1 (en) | 2018-07-26 | 2020-01-30 | Bayer Aktiengesellschaft | Novel triazole derivatives |
| EP3867224A1 (en) * | 2018-10-18 | 2021-08-25 | Boehringer Ingelheim International GmbH | Scalable synthesis of optically active 1-cyclopropylalkyl-1-amines |
| MX2023005073A (es) * | 2020-11-02 | 2023-05-16 | Merck Sharp & Dohme Llc | Agonistas macrociclicos de los receptores de urea orexina. |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2232038A1 (de) | 1972-06-30 | 1974-01-10 | Hoechst Ag | 3-amino-1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine, ihre herstellung und verwendung |
| PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| AU2001264313A1 (en) * | 2000-06-20 | 2002-01-02 | Japan Tobacco Inc. | Pyrazolopyridine compounds and use thereof as drugs |
| US6670364B2 (en) | 2001-01-31 | 2003-12-30 | Telik, Inc. | Antagonists of MCP-1 function and methods of use thereof |
| US6962926B2 (en) | 2001-01-31 | 2005-11-08 | Telik, Inc. | Antagonist of MCP-1 function, and compositions and methods of use thereof |
| US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| US7601876B2 (en) * | 2002-05-31 | 2009-10-13 | Proteotech, Inc. | Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis |
| EP1631260A2 (en) | 2003-02-28 | 2006-03-08 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| DE102004061288A1 (de) | 2004-12-14 | 2006-06-29 | Schering Ag | 3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel |
| AR057455A1 (es) | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| EP1764099A3 (en) | 2005-09-17 | 2007-05-09 | Speedel Experimenta AG | Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV |
| JP2007099640A (ja) | 2005-09-30 | 2007-04-19 | Tsumura & Co | 含窒素複素環化合物、その製造方法およびそれを用いた医薬組成物 |
| CA2647077A1 (en) * | 2006-04-26 | 2007-11-01 | Actelion Pharmaceuticals Ltd | Pyrazolo-tetrahydro pyridine derivatives as orexin receptor antagonists |
| TW200815438A (en) | 2006-06-13 | 2008-04-01 | Bayer Schering Pharma Ag | Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| EP1870410A1 (en) | 2006-06-13 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| GB0617161D0 (en) | 2006-08-31 | 2006-10-11 | Vernalis R&D Ltd | Enzyme inhibitors |
| CA2691638A1 (en) | 2007-07-03 | 2009-01-08 | Glaxo Group Limited | Piperidine derivatives useful as orexin receptor antagonists |
-
2010
- 2010-12-20 EP EP10805785.2A patent/EP2516437B1/en not_active Not-in-force
- 2010-12-20 JP JP2012545276A patent/JP2013515032A/ja active Pending
- 2010-12-20 CN CN2010800643114A patent/CN102762560A/zh active Pending
- 2010-12-20 ES ES10805785.2T patent/ES2460915T3/es active Active
- 2010-12-20 US US13/517,115 patent/US8742106B2/en not_active Expired - Fee Related
- 2010-12-20 WO PCT/EP2010/070260 patent/WO2011076744A1/en not_active Ceased
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