JP2018518990A5 - - Google Patents
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- JP2018518990A5 JP2018518990A5 JP2018517487A JP2018517487A JP2018518990A5 JP 2018518990 A5 JP2018518990 A5 JP 2018518990A5 JP 2018517487 A JP2018517487 A JP 2018517487A JP 2018517487 A JP2018517487 A JP 2018517487A JP 2018518990 A5 JP2018518990 A5 JP 2018518990A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- nucleic acid
- polypeptide
- acid molecule
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044885A JP7460675B2 (ja) | 2015-06-19 | 2022-03-22 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
| JP2024044396A JP2024073636A (ja) | 2015-06-19 | 2024-03-21 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15172913.4 | 2015-06-19 | ||
| EP15172913 | 2015-06-19 | ||
| PCT/EP2016/064195 WO2016203048A1 (en) | 2015-06-19 | 2016-06-20 | Pd-1-cd28 fusion proteins and their use in medicine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044885A Division JP7460675B2 (ja) | 2015-06-19 | 2022-03-22 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018518990A JP2018518990A (ja) | 2018-07-19 |
| JP2018518990A5 true JP2018518990A5 (OSRAM) | 2019-06-06 |
| JP7085988B2 JP7085988B2 (ja) | 2022-06-17 |
Family
ID=53476720
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517487A Active JP7085988B2 (ja) | 2015-06-19 | 2016-06-20 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
| JP2022044885A Active JP7460675B2 (ja) | 2015-06-19 | 2022-03-22 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
| JP2024044396A Pending JP2024073636A (ja) | 2015-06-19 | 2024-03-21 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044885A Active JP7460675B2 (ja) | 2015-06-19 | 2022-03-22 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
| JP2024044396A Pending JP2024073636A (ja) | 2015-06-19 | 2024-03-21 | Ｐｄ－１－ｃｄ２８融合タンパク質および医療におけるその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11192935B2 (OSRAM) |
| EP (3) | EP3909972B1 (OSRAM) |
| JP (3) | JP7085988B2 (OSRAM) |
| CN (3) | CN115927474A (OSRAM) |
| AU (1) | AU2016277883B2 (OSRAM) |
| CA (1) | CA2989949A1 (OSRAM) |
| DK (2) | DK3909972T5 (OSRAM) |
| ES (2) | ES2870174T3 (OSRAM) |
| FI (1) | FI3909972T3 (OSRAM) |
| HU (1) | HUE054201T2 (OSRAM) |
| PL (1) | PL3310805T3 (OSRAM) |
| PT (1) | PT3310805T (OSRAM) |
| WO (1) | WO2016203048A1 (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY196588A (en) | 2015-03-05 | 2023-04-19 | Hutchinson Fred Cancer Res | Immunomodulatory Fusion Proteins and uses Thereof |
| IL303905A (en) | 2015-05-18 | 2023-08-01 | Tcr2 Therapeutics Inc | Compositions and methods for TCR programming using fusion proteins |
| FI3909972T3 (fi) * | 2015-06-19 | 2024-05-03 | Sebastian Kobold | Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä |
| KR20180038447A (ko) * | 2015-06-29 | 2018-04-16 | 더 존스 홉킨스 유니버시티 | 면역 체크포인트 키메라 수용체 치료법 |
| CN105331585A (zh) * | 2015-11-13 | 2016-02-17 | 科济生物医药（上海）有限公司 | 携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞 |
| US11365237B2 (en) * | 2016-03-23 | 2022-06-21 | Helmholtz Zentrum Muenchen—Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) | Fusion proteins of PD-1 and 4-1BB |
| CN107523545A (zh) * | 2016-06-20 | 2017-12-29 | 上海细胞治疗研究院 | 一种高效稳定表达抗体的杀伤性细胞及其用途 |
| CN109476749A (zh) * | 2016-06-30 | 2019-03-15 | 豪夫迈·罗氏有限公司 | 改良的过继性t细胞疗法 |
| JP7109789B2 (ja) | 2016-08-02 | 2022-08-01 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を使用したｔｃｒの再プログラム化のための組成物及び方法 |
| ES2875959T3 (es) | 2016-10-07 | 2021-11-11 | Tcr2 Therapeutics Inc | Composiciones y métodos para reprogramación de receptores de linfocitos T mediante el uso de proteínas de fusión |
| AU2017363311A1 (en) | 2016-11-22 | 2019-06-13 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| EP3558348A1 (en) * | 2016-12-21 | 2019-10-30 | TCR2 Therapeutics Inc. | Engineered t cells for the treatment of cancer |
| US11535662B2 (en) * | 2017-01-26 | 2022-12-27 | Novartis Ag | CD28 compositions and methods for chimeric antigen receptor therapy |
| JP2020511136A (ja) | 2017-03-17 | 2020-04-16 | フレッド ハッチンソン キャンサー リサーチ センター | 免疫調節性融合タンパク質およびその使用 |
| US10780120B2 (en) * | 2018-03-06 | 2020-09-22 | The Trustees Of The University Of Pennsylvania | Prostate-specific membrane antigen cars and methods of use thereof |
| CN108727504B (zh) * | 2018-04-16 | 2021-08-27 | 泉州向日葵生物科技有限公司 | 一种ifn与抗pd-l1抗体的融合蛋白及其应用 |
| CN111606999B (zh) * | 2019-02-26 | 2022-09-06 | 南京惟亚德生物医药有限公司 | 兼具激活免疫共刺激信号通路和阻断免疫检查点的复制型溶瘤腺病毒及其应用 |
| CN120944827A (zh) * | 2019-03-27 | 2025-11-14 | 宾夕法尼亚大学董事会 | Tn-MUC1嵌合抗原受体(CAR)T细胞疗法 |
| AU2020315796A1 (en) * | 2019-07-19 | 2022-02-24 | Memorial Hospital For Cancer And Allied Diseases | Fusion polypeptide for immunotherapy |
| CN113832111A (zh) * | 2020-06-23 | 2021-12-24 | 南京大学 | 一种类外泌体技术用于制备新型溶瘤病毒的方法 |
| CN113832114A (zh) * | 2020-06-23 | 2021-12-24 | 南京大学 | 一种新型溶瘤腺病毒EM/VSV-G Ad5-P及其在制备抗肿瘤药物中的应用 |
| CA3211402A1 (en) * | 2021-03-10 | 2022-09-15 | Moshe ELKABETS | Reporter cells expressing chimeric polypeptides for use in determining presence and or activity of immune checkpoint molecules |
| CN120988097A (zh) * | 2021-04-11 | 2025-11-21 | 中国科学院分子细胞科学卓越创新中心 | 一种pd1变体及其用途 |
| EP4340862A4 (en) * | 2021-05-20 | 2025-05-21 | Achelois Biopharma, Inc. | Immune checkpoint multivalent particles compositions and methods of use |
| WO2023235479A1 (en) * | 2022-06-02 | 2023-12-07 | TCR2 Therapeutics Inc. | Compositions and methods for treating cancer |
| CN121057753A (zh) * | 2022-11-14 | 2025-12-02 | 阿奇洛伊斯生物制药公司 | 免疫检查点多价颗粒组合物和使用方法 |
| WO2025212859A1 (en) * | 2024-04-03 | 2025-10-09 | Solid Biosciences, Inc. | Methods and constructs for increasing solid organ transplant survival |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19822115B4 (de) | 1998-05-08 | 2004-04-08 | Heinrich-Pette-Institut | Retrovirale Gentransfervektoren |
| CN101287831B (zh) | 2005-09-13 | 2013-05-15 | 国立大学法人三重大学 | T细胞受体和编码该受体的核酸 |
| WO2010012829A1 (en) | 2008-07-31 | 2010-02-04 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Her2/neu specific t cell receptors |
| ZA200807283B (en) | 2008-08-22 | 2009-10-28 | Mechlift Invest Pty Ltd | Data unit for a bin lifting device |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CA2832540C (en) | 2011-04-08 | 2020-09-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer |
| US10981969B2 (en) * | 2011-07-29 | 2021-04-20 | The Trustees Of The University Of Pennsylvania | Switch costimulatory receptors |
| RU2644243C2 (ru) | 2011-10-20 | 2018-02-08 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные антигенные рецепторы к cd22 |
| US9688740B2 (en) * | 2011-10-26 | 2017-06-27 | National Cancer Center | Mutant CTLA4 gene transfected T cell and composition including same for anticancer immunotherapy |
| WO2013062365A2 (ko) * | 2011-10-26 | 2013-05-02 | 국립암센터 | 변이 ｃｔｌａ4 유전자 이입 ｔ 세포 및 이를 포함하는 항암 면역치료용 조성물 |
| CA2868121C (en) | 2012-03-23 | 2021-06-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-mesothelin chimeric antigen receptors |
| KR102086874B1 (ko) | 2012-04-11 | 2020-03-10 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | B-세포 성숙 항원을 표적화하는 키메라 항원 수용체 |
| GB201206559D0 (en) | 2012-04-13 | 2012-05-30 | Ucl Business Plc | Polypeptide |
| US9657105B2 (en) | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| WO2015028444A1 (en) | 2013-08-26 | 2015-03-05 | Universität Zu Köln | Anti cd30 chimeric antigen receptor and its use |
| BR112017011771A2 (pt) | 2014-12-02 | 2018-07-10 | Prospect Chartercare Rwmc Llc | métodos e composições para o tratamento de câncer |
| FI3909972T3 (fi) | 2015-06-19 | 2024-05-03 | Sebastian Kobold | Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä |
| CA3071661A1 (en) | 2017-09-06 | 2019-03-14 | Fred Hutchinson Cancer Research Center | Strep-tag specific chimeric receptors and uses thereof |
| CN110951718B (zh) * | 2019-12-02 | 2022-09-30 | 吉林凯莱英医药化学有限公司 | 共固定化酶、其制备方法及其应用 |
-
2016
- 2016-06-20 FI FIEP21155542.0T patent/FI3909972T3/fi active
- 2016-06-20 US US15/737,877 patent/US11192935B2/en active Active
- 2016-06-20 ES ES16736802T patent/ES2870174T3/es active Active
- 2016-06-20 EP EP21155542.0A patent/EP3909972B1/en active Active
- 2016-06-20 AU AU2016277883A patent/AU2016277883B2/en active Active
- 2016-06-20 PL PL16736802T patent/PL3310805T3/pl unknown
- 2016-06-20 WO PCT/EP2016/064195 patent/WO2016203048A1/en not_active Ceased
- 2016-06-20 DK DK21155542.0T patent/DK3909972T5/da active
- 2016-06-20 HU HUE16736802A patent/HUE054201T2/hu unknown
- 2016-06-20 ES ES21155542T patent/ES2976647T3/es active Active
- 2016-06-20 EP EP24156660.3A patent/EP4349854A3/en active Pending
- 2016-06-20 CN CN202210834160.0A patent/CN115927474A/zh active Pending
- 2016-06-20 JP JP2018517487A patent/JP7085988B2/ja active Active
- 2016-06-20 CN CN202210854297.2A patent/CN115925971A/zh active Pending
- 2016-06-20 CN CN201680048221.3A patent/CN108026151B/zh active Active
- 2016-06-20 CA CA2989949A patent/CA2989949A1/en active Pending
- 2016-06-20 DK DK16736802.6T patent/DK3310805T3/da active
- 2016-06-20 PT PT167368026T patent/PT3310805T/pt unknown
- 2016-06-20 EP EP16736802.6A patent/EP3310805B1/en active Active
-
2021
- 2021-10-29 US US17/515,250 patent/US20220169699A1/en active Pending
-
2022
- 2022-03-22 JP JP2022044885A patent/JP7460675B2/ja active Active
-
2024
- 2024-03-21 JP JP2024044396A patent/JP2024073636A/ja active Pending
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