JP2018516877A5 - - Google Patents
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- Publication number
- JP2018516877A5 JP2018516877A5 JP2017556212A JP2017556212A JP2018516877A5 JP 2018516877 A5 JP2018516877 A5 JP 2018516877A5 JP 2017556212 A JP2017556212 A JP 2017556212A JP 2017556212 A JP2017556212 A JP 2017556212A JP 2018516877 A5 JP2018516877 A5 JP 2018516877A5
- Authority
- JP
- Japan
- Prior art keywords
- igf
- antibody
- antigen
- binding fragment
- determining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 14
- 102000036639 antigens Human genes 0.000 claims 14
- 108091007433 antigens Proteins 0.000 claims 14
- 239000012634 fragment Substances 0.000 claims 14
- 239000012472 biological sample Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 210000004881 tumor cell Anatomy 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 238000000338 in vitro Methods 0.000 claims 7
- 230000037361 pathway Effects 0.000 claims 7
- 229940125644 antibody drug Drugs 0.000 claims 6
- 231100000590 oncogenic Toxicity 0.000 claims 6
- 230000002246 oncogenic effect Effects 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 2
- 238000001943 fluorescence-activated cell sorting Methods 0.000 claims 2
- 238000003364 immunohistochemistry Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 claims 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 238000010186 staining Methods 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000011285 therapeutic regimen Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020088582A JP6977105B2 (ja) | 2015-04-27 | 2020-05-21 | Ｉｇｆ−１ｒ抗体および癌の診断のためのその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305642 | 2015-04-27 | ||
| EP15305642.9 | 2015-04-27 | ||
| PCT/EP2016/059338 WO2016174053A1 (en) | 2015-04-27 | 2016-04-27 | Igf-1r antibody and its use for the diagnosis of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020088582A Division JP6977105B2 (ja) | 2015-04-27 | 2020-05-21 | Ｉｇｆ−１ｒ抗体および癌の診断のためのその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018516877A JP2018516877A (ja) | 2018-06-28 |
| JP2018516877A5 true JP2018516877A5 (enExample) | 2019-06-06 |
Family
ID=53039833
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017556212A Pending JP2018516877A (ja) | 2015-04-27 | 2016-04-27 | Ｉｇｆ−１ｒ抗体および癌の診断のためのその使用 |
| JP2020088582A Expired - Fee Related JP6977105B2 (ja) | 2015-04-27 | 2020-05-21 | Ｉｇｆ−１ｒ抗体および癌の診断のためのその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020088582A Expired - Fee Related JP6977105B2 (ja) | 2015-04-27 | 2020-05-21 | Ｉｇｆ−１ｒ抗体および癌の診断のためのその使用 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US10753937B2 (enExample) |
| EP (1) | EP3288979B1 (enExample) |
| JP (2) | JP2018516877A (enExample) |
| KR (1) | KR102350251B1 (enExample) |
| CN (1) | CN107690439B (enExample) |
| AR (1) | AR104413A1 (enExample) |
| AU (1) | AU2016254661B2 (enExample) |
| BR (1) | BR112017022974A2 (enExample) |
| CA (1) | CA2983548C (enExample) |
| CY (1) | CY1124070T1 (enExample) |
| DK (1) | DK3288979T3 (enExample) |
| ES (1) | ES2875753T3 (enExample) |
| HR (1) | HRP20210858T1 (enExample) |
| HU (1) | HUE054402T2 (enExample) |
| IL (1) | IL255273B (enExample) |
| LT (1) | LT3288979T (enExample) |
| MA (1) | MA41987B1 (enExample) |
| MX (1) | MX382055B (enExample) |
| MY (1) | MY187583A (enExample) |
| NZ (1) | NZ736924A (enExample) |
| PL (1) | PL3288979T3 (enExample) |
| PT (1) | PT3288979T (enExample) |
| RS (1) | RS62024B1 (enExample) |
| RU (1) | RU2706967C2 (enExample) |
| SA (1) | SA517390248B1 (enExample) |
| SI (1) | SI3288979T1 (enExample) |
| TN (1) | TN2017000451A1 (enExample) |
| TW (1) | TWI740824B (enExample) |
| UA (1) | UA121047C2 (enExample) |
| WO (1) | WO2016174053A1 (enExample) |
| ZA (1) | ZA201707249B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6968790B2 (ja) | 2015-10-26 | 2021-11-17 | ピエール、ファーブル、メディカマン | Ｉｇｆ−１ｒ発現癌の処置のための組成物 |
| CN111065653A (zh) * | 2017-05-23 | 2020-04-24 | 中央研究院 | 藉由预靶向的双特异性聚乙二醇结合抗体将聚乙二醇化试剂条件性内吞用于诊断和治疗 |
| RU2713795C1 (ru) * | 2019-06-13 | 2020-02-07 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ прогнозирования возможности озлокачествления опухоли яичника у женщин репродуктивного возраста |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101415728A (zh) * | 2006-03-28 | 2009-04-22 | 比奥根艾迪克Ma公司 | 抗-igf-1r抗体及其用途 |
| EA200802061A1 (ru) * | 2006-03-28 | 2009-04-28 | Байоджен Айдек Эмэй Инк. | Антитело или его фрагмент, специфично связывающееся с рецептором 1 инсулиноподобного фактора роста (igf-r1) (варианты), композиция на его основе, полинуклеотид, кодирующий вариабельную область антитела (варианты), содержащие полинуклеотид композиция (варианты) и вектор, содержащая вектор клетка-хозяин (варианты), способ продуцирования антитела или его фрагмента (варианты) и способ лечения гиперпролиферативного заболевания у животного организма |
| FR2906533B1 (fr) * | 2006-09-28 | 2013-02-22 | Pf Medicament | Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations |
| WO2008079849A2 (en) * | 2006-12-22 | 2008-07-03 | Genentech, Inc. | Antibodies to insulin-like growth factor receptor |
| US20130084243A1 (en) * | 2010-01-27 | 2013-04-04 | Liliane Goetsch | Igf-1r specific antibodies useful in the detection and diagnosis of cellular proliferative disorders |
| WO2009032145A1 (en) * | 2007-08-28 | 2009-03-12 | Biogen Idec Ma Inc. | Anti-igf-1r antibodies and uses thereof |
| EP2172485A1 (en) * | 2008-10-01 | 2010-04-07 | Pierre Fabre Medicament | Novel anti CXCR4 antibodies and their use for the treatment of cancer |
-
2016
- 2016-04-26 AR ARP160101176A patent/AR104413A1/es not_active Application Discontinuation
- 2016-04-26 TW TW105112967A patent/TWI740824B/zh not_active IP Right Cessation
- 2016-04-27 HU HUE16722812A patent/HUE054402T2/hu unknown
- 2016-04-27 UA UAA201711486A patent/UA121047C2/uk unknown
- 2016-04-27 MA MA41987A patent/MA41987B1/fr unknown
- 2016-04-27 LT LTEP16722812.1T patent/LT3288979T/lt unknown
- 2016-04-27 TN TNP/2017/000451A patent/TN2017000451A1/en unknown
- 2016-04-27 KR KR1020177032201A patent/KR102350251B1/ko not_active Expired - Fee Related
- 2016-04-27 ES ES16722812T patent/ES2875753T3/es active Active
- 2016-04-27 CN CN201680024231.3A patent/CN107690439B/zh not_active Expired - Fee Related
- 2016-04-27 WO PCT/EP2016/059338 patent/WO2016174053A1/en not_active Ceased
- 2016-04-27 AU AU2016254661A patent/AU2016254661B2/en not_active Ceased
- 2016-04-27 MX MX2017013808A patent/MX382055B/es unknown
- 2016-04-27 BR BR112017022974-9A patent/BR112017022974A2/pt not_active IP Right Cessation
- 2016-04-27 NZ NZ736924A patent/NZ736924A/en not_active IP Right Cessation
- 2016-04-27 PT PT167228121T patent/PT3288979T/pt unknown
- 2016-04-27 DK DK16722812.1T patent/DK3288979T3/da active
- 2016-04-27 SI SI201631234T patent/SI3288979T1/sl unknown
- 2016-04-27 RU RU2017140467A patent/RU2706967C2/ru active
- 2016-04-27 PL PL16722812T patent/PL3288979T3/pl unknown
- 2016-04-27 RS RS20210687A patent/RS62024B1/sr unknown
- 2016-04-27 HR HRP20210858TT patent/HRP20210858T1/hr unknown
- 2016-04-27 CA CA2983548A patent/CA2983548C/en active Active
- 2016-04-27 US US15/569,566 patent/US10753937B2/en not_active Expired - Fee Related
- 2016-04-27 JP JP2017556212A patent/JP2018516877A/ja active Pending
- 2016-04-27 EP EP16722812.1A patent/EP3288979B1/en active Active
- 2016-04-27 MY MYPI2017704030A patent/MY187583A/en unknown
-
2017
- 2017-10-25 ZA ZA2017/07249A patent/ZA201707249B/en unknown
- 2017-10-26 IL IL255273A patent/IL255273B/en active IP Right Grant
- 2017-10-26 SA SA517390248A patent/SA517390248B1/ar unknown
-
2020
- 2020-05-21 JP JP2020088582A patent/JP6977105B2/ja not_active Expired - Fee Related
- 2020-06-30 US US16/917,376 patent/US20210018508A1/en not_active Abandoned
-
2021
- 2021-04-26 CY CY20211100357T patent/CY1124070T1/el unknown
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