JP2017508475A5 - - Google Patents

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Publication number
JP2017508475A5
JP2017508475A5 JP2016559286A JP2016559286A JP2017508475A5 JP 2017508475 A5 JP2017508475 A5 JP 2017508475A5 JP 2016559286 A JP2016559286 A JP 2016559286A JP 2016559286 A JP2016559286 A JP 2016559286A JP 2017508475 A5 JP2017508475 A5 JP 2017508475A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
antigen
seq
antibody
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JP2016559286A
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English (en)
Japanese (ja)
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JP6865585B2 (ja
JP2017508475A (ja
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Priority claimed from GB1405477.9A external-priority patent/GB2524553C/en
Priority claimed from GB1405475.3A external-priority patent/GB2524552B/en
Application filed filed Critical
Priority claimed from PCT/EP2015/056654 external-priority patent/WO2015144855A1/en
Publication of JP2017508475A publication Critical patent/JP2017508475A/ja
Publication of JP2017508475A5 publication Critical patent/JP2017508475A5/ja
Priority to JP2021064572A priority Critical patent/JP7607498B2/ja
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Publication of JP6865585B2 publication Critical patent/JP6865585B2/ja
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JP2016559286A 2014-03-26 2015-03-26 成長分化因子１５（ｇｄｆ−１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用 Active JP6865585B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021064572A JP7607498B2 (ja) 2014-03-26 2021-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1405477.9A GB2524553C (en) 2014-03-26 2014-03-26 Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia
GB1405475.3A GB2524552B (en) 2014-03-26 2014-03-26 Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and use thereof for treating cancer
GB1405475.3 2014-03-26
GB1405477.9 2014-03-26
PCT/EP2015/056654 WO2015144855A1 (en) 2014-03-26 2015-03-26 Monoclonal antibodies to growth and differentiation factor 15 (gdf-15), and uses thereof for treating cancer cachexia and cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021064572A Division JP7607498B2 (ja) 2014-03-26 2021-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用

Publications (3)

Publication Number Publication Date
JP2017508475A JP2017508475A (ja) 2017-03-30
JP2017508475A5 true JP2017508475A5 (enExample) 2018-05-17
JP6865585B2 JP6865585B2 (ja) 2021-04-28

Family

ID=52745885

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016559286A Active JP6865585B2 (ja) 2014-03-26 2015-03-26 成長分化因子１５（ｇｄｆ−１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用
JP2021064572A Active JP7607498B2 (ja) 2014-03-26 2021-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用
JP2023062338A Withdrawn JP2023098966A (ja) 2014-03-26 2023-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021064572A Active JP7607498B2 (ja) 2014-03-26 2021-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用
JP2023062338A Withdrawn JP2023098966A (ja) 2014-03-26 2023-04-06 成長分化因子１５（ｇｄｆ－１５）に対するモノクローナル抗体およびがん悪液質およびがんを処置するためのその使用

Country Status (23)

Country Link
US (5) US20170204174A1 (enExample)
EP (3) EP3122775B1 (enExample)
JP (3) JP6865585B2 (enExample)
KR (1) KR102520978B1 (enExample)
CN (1) CN106536553B (enExample)
AU (2) AU2015238264B2 (enExample)
BR (1) BR122023027559A2 (enExample)
CA (1) CA2943694A1 (enExample)
CY (1) CY1122456T1 (enExample)
DK (2) DK3122775T3 (enExample)
ES (2) ES2763859T3 (enExample)
FI (1) FI3653644T3 (enExample)
HR (2) HRP20231514T1 (enExample)
HU (2) HUE047398T2 (enExample)
IL (2) IL248038B (enExample)
LT (2) LT3122775T (enExample)
NZ (1) NZ724649A (enExample)
PL (2) PL3122775T3 (enExample)
PT (2) PT3653644T (enExample)
RS (1) RS59700B1 (enExample)
SI (1) SI3122775T1 (enExample)
SM (1) SMT202000064T1 (enExample)
WO (1) WO2015144855A1 (enExample)

Families Citing this family (17)

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Publication number Priority date Publication date Assignee Title
DK3122775T3 (da) 2014-03-26 2020-02-03 Univ Wuerzburg J Maximilians Monoklonale antistoffer til vækst- og differentieringsfaktor 15 (gdf-15), og anvendelser deraf til behandling af cancer kakeksi og cancer
EP3197493B1 (en) 2014-09-25 2021-03-10 Aveo Pharmaceuticals Inc. Methods of reversing cachexia and prolonging survival comprising administering a gdf15 modulator and an anti-cancer agent
AU2016333538B2 (en) * 2015-10-02 2022-03-31 Julius-Maximilians-Universität Würzburg GDF-15 as a diagnostic marker to predict the clinical outcome of a treatment with immune checkpoint blockers
GB201517528D0 (en) * 2015-10-02 2015-11-18 Julius Maximillians Universitãt Würzburg GDF-15 as a diagnosis marker for melanoma
BR112018006218A2 (pt) 2015-10-02 2018-10-09 Univ Wuerzburg J Maximilians iinibidores de hgdf-15, seus usos, composição, kit, combinações e método in vitro para determinar se uma substância de interesse é um inibidor de hgdf-15
JP7138567B2 (ja) * 2016-04-27 2022-09-16 ノバルティス アーゲー 成長分化因子１５に対する抗体およびそれらの使用
MX389765B (es) * 2016-07-06 2025-03-20 Nat Res Council Canada Anticuerpos humanizados que transmigran a traves de la barrera hematoencefalica y usos de los mismos.
JP2020503842A (ja) * 2016-10-12 2020-02-06 ヤンセン バイオテツク，インコーポレーテツド Ｇｄｆ１５様生物活性の調節因子をスクリーニングするための方法
CA3045700A1 (en) * 2016-12-06 2018-06-14 St Vincent's Hospital Sydney Limited Treatment of obesity and eating disorders
KR102715542B1 (ko) * 2018-08-20 2024-10-08 화이자 인코포레이티드 항-gdf15 항체, 조성물 및 사용 방법
AU2021376864A1 (en) * 2020-11-10 2023-06-29 Catalym Gmbh Anti-gdf15 antibody and a dosage regimen for the treatment of cancer
BR112023020152A2 (pt) 2021-03-31 2023-11-14 Cambridge Entpr Ltd Inibidores terapêuticos de sinalização gdf15
US20250019427A1 (en) 2021-08-10 2025-01-16 Byomass Inc. Anti-gdf15 antibodies, compositions and uses thereof
WO2023122213A1 (en) 2021-12-22 2023-06-29 Byomass Inc. Targeting gdf15-gfral pathway cross-reference to related applications
WO2023217068A1 (zh) 2022-05-09 2023-11-16 舒泰神（北京）生物制药股份有限公司 特异性识别gdf15的抗体及其应用
CN116462757A (zh) * 2023-03-24 2023-07-21 科兴生物制药股份有限公司 Gdf15的单域抗体及其应用
CN118878677A (zh) * 2024-09-29 2024-11-01 江苏凯基生物技术股份有限公司 一种IgM亚型单克隆抗体及其制备方法和应用

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EP0953639A1 (en) * 1998-04-30 1999-11-03 Boehringer Ingelheim International GmbH FAPalpha-specific antibody with improved producibility
US6465181B2 (en) 1999-03-25 2002-10-15 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
DE60032355T2 (de) 1999-05-17 2007-04-26 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh NEUROPROTEKTIVE EIGENSCHAFTEN VON GDF-15, EINEM VERTRETER DER TGF-ß-SUPERFAMILIE
AU2001288770A1 (en) 2000-09-08 2002-03-22 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services A non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
EP3476861A1 (en) * 2004-01-07 2019-05-01 Novartis Vaccines and Diagnostics, Inc. M-csf-specific monoclonal antibody and uses thereof
ES2555956T3 (es) * 2004-04-13 2016-01-11 St Vincent's Hospital Sydney Limited Método para modular el apetito
WO2009021293A1 (en) * 2007-08-16 2009-02-19 St Vincent's Hospital Sydney Limited Agents and methods for modulating macrophage inhibitory cytokine (mic-1) activity
JP2011502106A (ja) * 2007-10-09 2011-01-20 セントビンセンツ ホスピタル シドニー リミテッド マクロファージ阻害性サイトカイン−１を除去又は不活性化して悪液質を治療する方法
WO2010034443A1 (en) 2008-09-29 2010-04-01 F. Hoffmann-La Roche Ag Antibodies against human il 17 and uses thereof
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MX2014009129A (es) 2012-01-26 2014-11-21 Amgen Inc Polipeptidos de factor 15 de diferenciacion de crecimiento (gdf-15).
EP3590537A1 (en) * 2012-09-26 2020-01-08 Julius-Maximilians-Universität Würzburg Monoclonal antibodies to growth and differentiation factor 15 (gdf-15)
WO2014100689A1 (en) * 2012-12-21 2014-06-26 Aveo Pharmaceuticals, Inc. Anti-gdf15 antibodies
DK3122775T3 (da) 2014-03-26 2020-02-03 Univ Wuerzburg J Maximilians Monoklonale antistoffer til vækst- og differentieringsfaktor 15 (gdf-15), og anvendelser deraf til behandling af cancer kakeksi og cancer

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