MX2016005765A - Anticuerpos anti-il-17, un metodo para producir y utilizar los mismos. - Google Patents

Anticuerpos anti-il-17, un metodo para producir y utilizar los mismos.

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Publication number
MX2016005765A
MX2016005765A MX2016005765A MX2016005765A MX2016005765A MX 2016005765 A MX2016005765 A MX 2016005765A MX 2016005765 A MX2016005765 A MX 2016005765A MX 2016005765 A MX2016005765 A MX 2016005765A MX 2016005765 A MX2016005765 A MX 2016005765A
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MX
Mexico
Prior art keywords
antibodies
relates
same
specifically
producing
Prior art date
Application number
MX2016005765A
Other languages
English (en)
Inventor
Borisovich ULITIN Andrey
Rudolfovich EVDOKIMOV Stanislav
Vladimirovich Soloviev Valeriy
Sergeevna Chernyh Yulia
Vladimirovna Goncharova Olga
Valerievich KORZHAVIN Dmitriy
Veniaminovna Chernovskaya Tatyana
Alexeevich IVANOV Roman
Valentinovich Morozov Dmitriy
Original Assignee
Biocad Cjsc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocad Cjsc filed Critical Biocad Cjsc
Publication of MX2016005765A publication Critical patent/MX2016005765A/es

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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

La presente invención se relaciona con el campo de la medicina, y de manera específica, con el campo de los anticuerpos monoclonales contra la IL-17 humana. De manera más específica, la invención se relaciona con anticuerpos monoclonales/antagonistas de la IL-17A, que se unen con alta afinidad a un epitopo de la IL-17, en donde los anticuerpos contienen sustituciones de aminoácidos en las regiones hipervariables de las cadenas pesada y ligera. Los anticuerpos de acuerdo con la invención pueden ser anticuerpos quiméricos, humanizados o humanos, o fragmentos que se unen al antígeno de los mismos, y pueden utilizarse como un agente medicinal para el tratamiento de trastornos autoinmunes e inflamatorios y trastornos de la proliferación y desarrollo celular. La invención también se relaciona con métodos para producir los anticuerpos.
MX2016005765A 2014-03-14 2014-10-27 Anticuerpos anti-il-17, un metodo para producir y utilizar los mismos. MX2016005765A (es)

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RU2014109854/10A RU2577228C2 (ru) 2014-03-14 2014-03-14 Анти-il-17-антитела, способ их получения и способ применения
PCT/RU2014/000808 WO2015137843A1 (ru) 2014-03-14 2014-10-27 Анти-il-17-антитела, способ их получения и способ применения

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WO2020024931A1 (en) * 2018-07-31 2020-02-06 Shen Weiqun Anti-il-17a antibodies and use thereof
CN111303283A (zh) * 2018-12-12 2020-06-19 上海君实生物医药科技股份有限公司 抗il-17a抗体及其应用
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CN113631574A (zh) * 2019-01-31 2021-11-09 努玛治疗有限公司 对TNFα和IL-17A具有特异性的多特异性抗体、靶向IL-17A的抗体及其使用方法
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CN116063493B (zh) * 2022-07-22 2023-09-01 贵州省赛尔生物科技有限公司 包含抗体和间充质干细胞外泌体的药物组合物及其制备方法
CN117820475A (zh) * 2023-12-21 2024-04-05 北京贝来生物科技有限公司 针对il-17a的新型纳米抗体、药物、制备、方法及应用
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EP3130604A1 (en) 2017-02-15
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