BR112016010513A2 - anticorpos anti-il-17, método de produção e uso dos mesmos - Google Patents

anticorpos anti-il-17, método de produção e uso dos mesmos

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Publication number
BR112016010513A2
BR112016010513A2 BR112016010513A BR112016010513A BR112016010513A2 BR 112016010513 A2 BR112016010513 A2 BR 112016010513A2 BR 112016010513 A BR112016010513 A BR 112016010513A BR 112016010513 A BR112016010513 A BR 112016010513A BR 112016010513 A2 BR112016010513 A2 BR 112016010513A2
Authority
BR
Brazil
Prior art keywords
antibodies
relates
specifically
human
production
Prior art date
Application number
BR112016010513A
Other languages
English (en)
Inventor
Borisovich ULITIN Andrey
Valentinovich Morozov Dmitriy
Valerievich KORZHAVIN Dmitriy
Vladimirovna Goncharova Olga
Alexeevich IVANOV Roman
Rudolfovich EVDOKIMOV Stanislav
Veniaminovna Chernovskaya Tatyana
Vladimirovich Soloviev Valeriy
Sergeevna Chernyh Yulia
Original Assignee
Cjsc Biocad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cjsc Biocad filed Critical Cjsc Biocad
Publication of BR112016010513A2 publication Critical patent/BR112016010513A2/pt

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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

resumo ?anticorpos anti-il-17, método de produção e uso dos mesmos? a presente invenção refere-se ao campo de medicina e especificamente ao campo de anticorpos monoclonais contra il-17 humana. mais especificamente a invenção refere-se a anticorpos monoclonais/antagonistas de il-17a, que se ligam com elevada afinidade a um epitopo il-17, sendo que os anticorpos contém contain substituições de aminoácidos in regiões hipervariáveis of cadeias pesadas e leves. os anticorpos de acordo com esta invenção podem ser anticorpos quiméricos, humanizados ou humanos ou fragmentos de ligação a antígeno deste, e podem ser usados como agente medicinal para tratamento de distúrbios autoimunes e inflamatórios e distúrbios de proliferação celular e desenvolvimento celular. a invenção também se refere a métodos de produção de ditos anticorpos.
BR112016010513A 2014-03-14 2014-10-27 anticorpos anti-il-17, método de produção e uso dos mesmos BR112016010513A2 (pt)

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RU2014109854/10A RU2577228C2 (ru) 2014-03-14 2014-03-14 Анти-il-17-антитела, способ их получения и способ применения
PCT/RU2014/000808 WO2015137843A1 (ru) 2014-03-14 2014-10-27 Анти-il-17-антитела, способ их получения и способ применения

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TW201538524A (zh) 2015-10-16
US10442857B2 (en) 2019-10-15
RU2577228C2 (ru) 2016-03-10
EP3130604A4 (en) 2017-11-01
ZA201602040B (en) 2017-02-22
RU2014109854A (ru) 2015-09-20
US20170081401A1 (en) 2017-03-23
AR100573A1 (es) 2016-10-19
WO2015137843A1 (ru) 2015-09-17
EA034854B1 (ru) 2020-03-30
CN106795219A (zh) 2017-05-31
JP2017508463A (ja) 2017-03-30
MX2016005765A (es) 2017-01-05
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