JP2018514209A5 - - Google Patents
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- Publication number
- JP2018514209A5 JP2018514209A5 JP2017555767A JP2017555767A JP2018514209A5 JP 2018514209 A5 JP2018514209 A5 JP 2018514209A5 JP 2017555767 A JP2017555767 A JP 2017555767A JP 2017555767 A JP2017555767 A JP 2017555767A JP 2018514209 A5 JP2018514209 A5 JP 2018514209A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- signal peptide
- acid construct
- cell
- hydrophobic amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1507108.7 | 2015-04-27 | ||
| GBGB1507108.7A GB201507108D0 (en) | 2015-04-27 | 2015-04-27 | Nucleic acid construct |
| PCT/GB2016/051165 WO2016174409A1 (en) | 2015-04-27 | 2016-04-26 | Nucleic acid construct |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117041A Division JP2020182473A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018514209A JP2018514209A (ja) | 2018-06-07 |
| JP2018514209A5 true JP2018514209A5 (enExample) | 2019-04-11 |
| JP6836516B2 JP6836516B2 (ja) | 2021-03-03 |
Family
ID=53488690
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555767A Active JP6836516B2 (ja) | 2015-04-27 | 2016-04-26 | 核酸構築物 |
| JP2020117041A Withdrawn JP2020182473A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117041A Withdrawn JP2020182473A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11613559B2 (enExample) |
| EP (1) | EP3288582B1 (enExample) |
| JP (2) | JP6836516B2 (enExample) |
| CN (1) | CN107532175A (enExample) |
| AU (1) | AU2016254499A1 (enExample) |
| CA (1) | CA2983687A1 (enExample) |
| ES (1) | ES2869971T3 (enExample) |
| GB (1) | GB201507108D0 (enExample) |
| HK (1) | HK1243958A1 (enExample) |
| WO (1) | WO2016174409A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102211120B1 (ko) | 2014-05-15 | 2021-02-03 | 내셔널 유니버시티 오브 싱가포르 | 변형된 천연 살해 세포 및 그의 용도 |
| IL269553B2 (en) | 2017-03-27 | 2025-10-01 | Nat Univ Singapore | Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells |
| WO2018182511A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| SG11202008976YA (en) | 2018-04-02 | 2020-10-29 | Nat Univ Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| GB201805918D0 (en) | 2018-04-10 | 2018-05-23 | Autolus Ltd | Cell |
| GB201812474D0 (en) | 2018-07-31 | 2018-09-12 | Autolus Ltd | Nucleic acid construct |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| WO2020180882A1 (en) | 2019-03-05 | 2020-09-10 | Nkarta, Inc. | Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| GB201914611D0 (en) | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| GB202007044D0 (en) | 2020-05-13 | 2020-06-24 | Autolus Ltd | Method |
| JP2022072823A (ja) | 2020-10-30 | 2022-05-17 | 藤森工業株式会社 | 包装袋 |
| JP2024500847A (ja) | 2020-12-18 | 2024-01-10 | センチュリー セラピューティクス，インコーポレイテッド | 適合可能な受容体特異性を有するキメラ抗原受容体システム |
| GB202108184D0 (en) | 2021-06-08 | 2021-07-21 | Autolus Ltd | Engineered immune cell |
| WO2023139360A1 (en) | 2022-01-19 | 2023-07-27 | Autolus Limited | Nucleic acid construct |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4418900A (en) | 1999-04-16 | 2000-11-02 | Celltech Therapeutics Limited | Synthetic transmembrane components |
| EP2468881A3 (en) * | 2005-07-21 | 2012-08-15 | Abbott Laboratories | Multiple gene expression including sorf contructs and methods with polyproteins, pro-proteins, and proteolysis |
| SI2496601T1 (sl) * | 2009-11-05 | 2017-09-29 | F. Hoffmann-La Roche Ag | Tehnike in sestavek za sekrecijo heterolognih polipeptidov |
| CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
| GB201317929D0 (en) * | 2013-10-10 | 2013-11-27 | Ucl Business Plc | Chimeric antigen receptor |
| MX377283B (es) * | 2013-11-21 | 2025-03-07 | Ucl Business Ltd | Célula t o nk que coexpresa un receptor antigénico quimérico (car). |
| GB201507104D0 (en) | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic acid construct |
-
2015
- 2015-04-27 GB GBGB1507108.7A patent/GB201507108D0/en not_active Ceased
-
2016
- 2016-04-26 WO PCT/GB2016/051165 patent/WO2016174409A1/en not_active Ceased
- 2016-04-26 ES ES16720484T patent/ES2869971T3/es active Active
- 2016-04-26 US US15/568,862 patent/US11613559B2/en active Active
- 2016-04-26 CN CN201680022736.6A patent/CN107532175A/zh active Pending
- 2016-04-26 JP JP2017555767A patent/JP6836516B2/ja active Active
- 2016-04-26 CA CA2983687A patent/CA2983687A1/en not_active Abandoned
- 2016-04-26 EP EP16720484.1A patent/EP3288582B1/en active Active
- 2016-04-26 AU AU2016254499A patent/AU2016254499A1/en not_active Abandoned
- 2016-04-26 HK HK18103620.2A patent/HK1243958A1/zh unknown
-
2020
- 2020-07-07 JP JP2020117041A patent/JP2020182473A/ja not_active Withdrawn
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