JP2018508571A5 - - Google Patents
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- Publication number
- JP2018508571A5 JP2018508571A5 JP2017560858A JP2017560858A JP2018508571A5 JP 2018508571 A5 JP2018508571 A5 JP 2018508571A5 JP 2017560858 A JP2017560858 A JP 2017560858A JP 2017560858 A JP2017560858 A JP 2017560858A JP 2018508571 A5 JP2018508571 A5 JP 2018508571A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- glp
- light chain
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510071304.1 | 2015-02-11 | ||
| CN201510071304 | 2015-02-11 | ||
| PCT/CN2016/073279 WO2016127887A1 (zh) | 2015-02-11 | 2016-02-03 | 一种药用glp-1r抗体融合蛋白的稳定溶液制剂 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018508571A JP2018508571A (ja) | 2018-03-29 |
| JP2018508571A5 true JP2018508571A5 (enExample) | 2020-06-18 |
| JP6731953B2 JP6731953B2 (ja) | 2020-07-29 |
Family
ID=56615305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560858A Active JP6731953B2 (ja) | 2015-02-11 | 2016-02-03 | Ｇｌｐ−１ｒ抗体融合タンパク質の安定な医薬溶液製剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10485870B2 (enExample) |
| EP (1) | EP3257524B1 (enExample) |
| JP (1) | JP6731953B2 (enExample) |
| KR (1) | KR102568272B1 (enExample) |
| CN (2) | CN105854000A (enExample) |
| AU (1) | AU2016218759B2 (enExample) |
| DK (1) | DK3257524T3 (enExample) |
| ES (1) | ES2833099T3 (enExample) |
| PL (1) | PL3257524T3 (enExample) |
| PT (1) | PT3257524T (enExample) |
| WO (1) | WO2016127887A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3684793A1 (en) | 2017-09-22 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Glucagon-like peptide 1 receptor agonists and uses thereof |
| WO2024064842A1 (en) | 2022-09-21 | 2024-03-28 | Regeneron Pharmaceuticals, Inc. | Methods of treating obesity, diabetes, and liver dysfunction |
| CN120379686A (zh) * | 2022-10-19 | 2025-07-25 | 伊莱利利公司 | 含防腐剂的gip/glp激动剂组合物 |
| WO2026021575A1 (zh) * | 2024-07-26 | 2026-01-29 | 鸿运华宁（杭州）生物医药有限公司 | 一种gipr抗体融合蛋白质的药用稳定溶液制剂及其应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9409496D0 (en) | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
| US6006753A (en) | 1996-08-30 | 1999-12-28 | Eli Lilly And Company | Use of GLP-1 or analogs to abolish catabolic changes after surgery |
| US6277819B1 (en) | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
| UA65549C2 (uk) | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
| SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Hellstroem | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
| US5899883A (en) | 1998-07-08 | 1999-05-04 | Jinq Shing Chern | Safety syringe |
| ATE251465T1 (de) | 1998-07-31 | 2003-10-15 | Novo Nordisk As | In-vitro stimulation von beta zellen vermehrung |
| MY155270A (en) | 1998-09-24 | 2015-09-30 | Lilly Co Eli | Use of glp-1 or analogs in treatment of stroke |
| KR20030027077A (ko) * | 2000-09-01 | 2003-04-03 | 쥬가이 세이야쿠 가부시키가이샤 | 장기 안정화 용액 제제 |
| IL155812A0 (en) | 2000-12-07 | 2003-12-23 | Lilly Co Eli | Glp-1 fusion proteins |
| CN101128487B (zh) | 2004-12-02 | 2012-10-10 | 杜门蒂斯有限公司 | 靶向血清白蛋白和glp-1或pyy的双特异性结构域抗体 |
| DK1831252T3 (da) * | 2004-12-22 | 2009-10-05 | Lilly Co Eli | GLP-1 analog fusionsproteinformuleringer |
| US20060275288A1 (en) | 2005-01-20 | 2006-12-07 | Grihalde Nelson D | GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof |
| DE602005017628D1 (de) | 2005-09-22 | 2009-12-24 | Biocompatibles Uk Ltd | Fusionspolypeptide vom glp-1 (glucagon-like peptide-1) mit erhöhten peptidaseresistenz |
| US20090098130A1 (en) | 2007-01-05 | 2009-04-16 | Bradshaw Curt W | Glucagon-like protein-1 receptor (glp-1r) agonist compounds |
| ATE499088T1 (de) * | 2007-07-10 | 2011-03-15 | Lilly Co Eli | Glp-1-fc fusionsprotein-formulierung |
| US20090021453A1 (en) | 2007-07-19 | 2009-01-22 | Zachary Smith | Fashion accessory including alternating light emitting and non-light emitting elements of consistent lengths |
| JP2011503000A (ja) * | 2007-11-02 | 2011-01-27 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 半合成ＧＬＰ−１ペプチド−Ｆｃ融合コンストラクト、その方法及び使用 |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| SG189682A1 (en) | 2008-03-31 | 2013-05-31 | Glaxo Group Ltd | Drug fusions and conjugates |
| ES2617281T3 (es) | 2009-10-28 | 2017-06-16 | Janssen Biotech, Inc. | Anticuerpos anti-glp-1r y sus usos |
| EP2501367B1 (en) | 2009-11-17 | 2015-01-21 | Ipsen Pharma S.A.S. | Formulation for HGH and RHIGF-1 combination |
| CN102961745B (zh) * | 2012-09-27 | 2015-02-18 | 苏州康聚生物科技有限公司 | 抗体组合物制剂及其应用 |
| CN104371019B (zh) * | 2013-08-13 | 2019-09-10 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
-
2016
- 2016-02-03 PT PT167486885T patent/PT3257524T/pt unknown
- 2016-02-03 ES ES16748688T patent/ES2833099T3/es active Active
- 2016-02-03 AU AU2016218759A patent/AU2016218759B2/en active Active
- 2016-02-03 CN CN201610077253.8A patent/CN105854000A/zh active Pending
- 2016-02-03 KR KR1020177023260A patent/KR102568272B1/ko active Active
- 2016-02-03 US US15/547,727 patent/US10485870B2/en active Active
- 2016-02-03 JP JP2017560858A patent/JP6731953B2/ja active Active
- 2016-02-03 CN CN202610244442.3A patent/CN121927035A/zh active Pending
- 2016-02-03 WO PCT/CN2016/073279 patent/WO2016127887A1/zh not_active Ceased
- 2016-02-03 EP EP16748688.5A patent/EP3257524B1/en active Active
- 2016-02-03 PL PL16748688T patent/PL3257524T3/pl unknown
- 2016-02-03 DK DK16748688.5T patent/DK3257524T3/da active
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