JP2018510132A5 - - Google Patents
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- JP2018510132A5 JP2018510132A5 JP2017540830A JP2017540830A JP2018510132A5 JP 2018510132 A5 JP2018510132 A5 JP 2018510132A5 JP 2017540830 A JP2017540830 A JP 2017540830A JP 2017540830 A JP2017540830 A JP 2017540830A JP 2018510132 A5 JP2018510132 A5 JP 2018510132A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562111261P | 2015-02-03 | 2015-02-03 | |
| US62/111,261 | 2015-02-03 | ||
| PCT/US2016/016165 WO2016126702A1 (en) | 2015-02-03 | 2016-02-02 | Anti-cd40l antibodies and methods for treating cd40l-related diseases or disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020191310A Division JP2021054826A (ja) | 2015-02-03 | 2020-11-18 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018510132A JP2018510132A (ja) | 2018-04-12 |
| JP2018510132A5 true JP2018510132A5 (enExample) | 2019-03-14 |
| JP6797810B2 JP6797810B2 (ja) | 2020-12-09 |
Family
ID=56564599
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540830A Active JP6797810B2 (ja) | 2015-02-03 | 2016-02-02 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
| JP2020191310A Withdrawn JP2021054826A (ja) | 2015-02-03 | 2020-11-18 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
| JP2022199466A Pending JP2023036717A (ja) | 2015-02-03 | 2022-12-14 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
| JP2025006366A Pending JP2025081304A (ja) | 2015-02-03 | 2025-01-16 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020191310A Withdrawn JP2021054826A (ja) | 2015-02-03 | 2020-11-18 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
| JP2022199466A Pending JP2023036717A (ja) | 2015-02-03 | 2022-12-14 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
| JP2025006366A Pending JP2025081304A (ja) | 2015-02-03 | 2025-01-16 | Ｃｄ４０ｌ関連疾患または障害を治療するための抗ｃｄ４０ｌ抗体及び方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US10106618B2 (enExample) |
| EP (2) | EP4071175A1 (enExample) |
| JP (4) | JP6797810B2 (enExample) |
| KR (2) | KR102747565B1 (enExample) |
| CN (2) | CN114195895B (enExample) |
| AU (3) | AU2016215505B8 (enExample) |
| CA (1) | CA2974135A1 (enExample) |
| DK (1) | DK3253412T3 (enExample) |
| GB (1) | GB2552429A (enExample) |
| IL (3) | IL322241A (enExample) |
| MA (1) | MA41459A (enExample) |
| MX (2) | MX392480B (enExample) |
| RU (1) | RU2727646C2 (enExample) |
| SG (2) | SG10201912752QA (enExample) |
| WO (1) | WO2016126702A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE065915T2 (hu) | 2011-03-11 | 2024-06-28 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antitestek és alkalmazásaik |
| MA41459A (fr) * | 2015-02-03 | 2017-12-12 | Als Therapy Development Inst | Anticorps anti-cd40l et méthodes pour traiter des maladies ou des troubles liés aux cd40l |
| WO2017040932A1 (en) | 2015-09-04 | 2017-03-09 | Primatope Therapeutics Inc. | Humanized anti-cd40 antibodies and uses thereof |
| EP3630843A2 (en) * | 2017-05-24 | 2020-04-08 | ALS Therapy Development Institute | Therapeutic anti-cd40 ligand antibodies |
| DK3993876T3 (en) * | 2019-07-01 | 2024-12-02 | Tonix Pharma Ltd | Anti-cd154 antibodies and uses thereof |
| CN114341197A (zh) * | 2019-07-08 | 2022-04-12 | 普罗根有限公司 | 新的融合蛋白及其用途 |
| KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
| BR112022020256A2 (pt) | 2020-04-09 | 2023-01-03 | Aprilbio Co Ltd | anticorpo monoclonal ou um fragmento de ligação ao antígeno do mesmo, ácido nucleico, vetor de expressão, célula, composição, uso da composição e uso do anticorpo monoclonal ou fragmento de ligação ao antígeno do mesmo |
| AU2022205313A1 (en) * | 2021-01-06 | 2023-07-20 | Tonix Pharma Limited | Methods of inducing immune tolerance with modified anti-cd154 antibodies |
| AU2022218137A1 (en) | 2021-02-03 | 2023-08-24 | Mozart Therapeutics, Inc. | Binding agents and methods of using the same |
| WO2023076876A1 (en) | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| CN114149508B (zh) * | 2021-11-25 | 2023-04-28 | 苏州普乐康医药科技有限公司 | 一种结合cd40l的融合蛋白及其应用 |
| KR20230108156A (ko) * | 2022-01-10 | 2023-07-18 | 주식회사 금호에이치티 | Cd40l에 특이적으로 결합하는 항체 및 그의 용도 |
| WO2024211211A1 (en) | 2023-04-03 | 2024-10-10 | Regeneron Pharmaceuticals, Inc. | Methods of improving transplant survival using il-2 receptor gamma chain antibodies |
| KR20260116248A (ko) | 2023-11-28 | 2026-07-28 | 엘레던 파마슈티컬즈, 아이엔씨. | 이식 거부반응 예방을 위한 방법 및 조성물 |
| WO2025235670A1 (en) | 2024-05-07 | 2025-11-13 | Eledon Pharmaceuticals, Inc. | Use of anti-cd40 ligand antibodies for immunosuppression in islet cell transplantation |
| WO2025235683A1 (en) | 2024-05-07 | 2025-11-13 | Eledon Pharmaceuticals, Inc. | Methods and compositions for prevention of transplant rejection |
| WO2026092377A1 (zh) * | 2024-10-28 | 2026-05-07 | 信达生物制药(苏州)有限公司 | 用cd40l抗体治疗自身免疫病 |
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| US5851795A (en) | 1991-06-27 | 1998-12-22 | Bristol-Myers Squibb Company | Soluble CTLA4 molecules and uses thereof |
| US5637481A (en) | 1993-02-01 | 1997-06-10 | Bristol-Myers Squibb Company | Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell |
| US5961974A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same |
| US5962406A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US7070777B1 (en) | 1991-11-15 | 2006-07-04 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
| US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| CA2089229C (en) | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Cd40cr receptor and ligands therefor |
| CN1127351C (zh) | 1993-09-02 | 2003-11-12 | 达特茅斯学院理事 | 诱导抗原特异性ｔ细胞耐受的方法 |
| US5833987A (en) | 1995-06-07 | 1998-11-10 | Trustees Of Dartmouth College | Treatment of T cell mediated autoimmune disorders |
| US6001358A (en) | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
| CN1572325A (zh) | 1997-01-10 | 2005-02-02 | 拜奥根Idec马萨诸塞公司 | 用抗cd40l化合物治疗狼疮性肾炎 |
| SK156099A3 (en) | 1997-05-17 | 2000-06-12 | Biogen Inc | Use of a cd40:cd154 binding interruptor to prevent counter adaptive immune responses, particularly graft rejection |
| CN100352497C (zh) | 1998-04-03 | 2007-12-05 | 达特茅斯学院理事 | 应用特异性结合cd40cr(cd40 配体)的抗体抑制体液免疫 |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| KR20020072277A (ko) | 1999-11-08 | 2002-09-14 | 아이덱 파마슈티칼즈 코포레이션 | 항-ｃｄ20 항체 및/또는 화학요법 및 방사선요법과결합하여 항-ｃｄ40ｌ 항체를 이용한 ｂ세포 악성종양의치료방법 |
| MXPA02007473A (es) | 2000-02-01 | 2003-09-22 | Tanox Inc | Moleculas activadoras de celulas presentadoras de antigenos (apc) que se unen a cd40. |
| GB0006398D0 (en) | 2000-03-16 | 2000-05-03 | Novartis Ag | Organic compounds |
| WO2001083755A2 (en) | 2000-04-28 | 2001-11-08 | La Jolla Institute For Allergy And Immunology | Human anti-cd40 antibodies and methods of making and using same |
| EP1284747A2 (en) * | 2000-05-12 | 2003-02-26 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for achieving immune suppression |
| JP2004502742A (ja) | 2000-07-12 | 2004-01-29 | アイデック ファーマスーティカルズ コーポレイション | Ｂ細胞を消滅させる抗体及び免疫調節抗体を併用するｂ細胞悪性疾患の治療関連出願 |
| NZ524980A (en) | 2000-09-01 | 2005-10-28 | Biogen Idec Inc | Novel CD40:CD154 binding interruptor compounds and use thereof to treat immunological complications |
| AU8867501A (en) | 2000-09-01 | 2002-03-13 | Biogen Inc | Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design |
| AU2003217912A1 (en) * | 2002-03-01 | 2003-09-16 | Xencor | Antibody optimization |
| WO2004037204A2 (en) | 2002-10-25 | 2004-05-06 | University Of South Florida | Methods and compounds for disruption of cd40r/cd40l signaling in the treatment of alzheimer's disease |
| DK1639014T3 (da) | 2003-06-13 | 2011-01-17 | Biogen Idec Inc | Aglycosyl-anti-CD154 (CD40-ligand)-antistoffer og anvendelser deraf |
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| JP4944608B2 (ja) | 2003-07-26 | 2012-06-06 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 改良された抗原結合親和性を有する、変更された抗体 |
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| NO2699601T3 (enExample) * | 2011-04-21 | 2018-06-16 | ||
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| SMT202000091T1 (it) | 2011-10-13 | 2020-05-08 | Bristol Myers Squibb Co | Polipeptidi anticorpali che antagonizzano cd40l |
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| CN105121621B (zh) | 2012-10-18 | 2019-08-02 | 张永新 | 用于细胞动静态交替培养的生物反应器系统及其方法 |
| SG11201508170TA (en) * | 2013-04-02 | 2015-11-27 | Chugai Pharmaceutical Co Ltd | Fc REGION VARIANT |
| EP3712166A1 (en) * | 2013-09-05 | 2020-09-23 | Amgen Inc. | Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles |
| US20170051059A1 (en) | 2014-03-19 | 2017-02-23 | Bristol-Myers Squibb Company | Methods of treating transplant rejection using a domain antibody directed against cd40 |
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| US20170233485A1 (en) | 2014-08-18 | 2017-08-17 | Biogen Ma Inc. | Anti-cd40 antibodies and uses thereof |
| MA41459A (fr) * | 2015-02-03 | 2017-12-12 | Als Therapy Development Inst | Anticorps anti-cd40l et méthodes pour traiter des maladies ou des troubles liés aux cd40l |
| EP3630843A2 (en) | 2017-05-24 | 2020-04-08 | ALS Therapy Development Institute | Therapeutic anti-cd40 ligand antibodies |
-
2016
- 2016-02-01 MA MA041459A patent/MA41459A/fr unknown
- 2016-02-02 IL IL322241A patent/IL322241A/en unknown
- 2016-02-02 DK DK16747111.9T patent/DK3253412T3/da active
- 2016-02-02 CA CA2974135A patent/CA2974135A1/en active Pending
- 2016-02-02 SG SG10201912752QA patent/SG10201912752QA/en unknown
- 2016-02-02 CN CN202111202841.7A patent/CN114195895B/zh active Active
- 2016-02-02 CN CN201680008506.4A patent/CN108064168B/zh active Active
- 2016-02-02 WO PCT/US2016/016165 patent/WO2016126702A1/en not_active Ceased
- 2016-02-02 JP JP2017540830A patent/JP6797810B2/ja active Active
- 2016-02-02 RU RU2017126997A patent/RU2727646C2/ru active
- 2016-02-02 SG SG11201706258WA patent/SG11201706258WA/en unknown
- 2016-02-02 GB GB1713871.0A patent/GB2552429A/en not_active Withdrawn
- 2016-02-02 EP EP22163613.7A patent/EP4071175A1/en active Pending
- 2016-02-02 EP EP16747111.9A patent/EP3253412B1/en active Active
- 2016-02-02 AU AU2016215505A patent/AU2016215505B8/en active Active
- 2016-02-02 KR KR1020177021029A patent/KR102747565B1/ko active Active
- 2016-02-02 MX MX2017009694A patent/MX392480B/es unknown
- 2016-02-02 KR KR1020247042620A patent/KR20250007045A/ko active Pending
-
2017
- 2017-07-19 IL IL253571A patent/IL253571B/en unknown
- 2017-07-26 MX MX2022005655A patent/MX2022005655A/es unknown
- 2017-08-02 US US15/667,477 patent/US10106618B2/en active Active
-
2018
- 2018-09-07 US US16/125,317 patent/US10683356B2/en active Active
-
2020
- 2020-05-13 US US15/931,315 patent/US11014990B2/en active Active
- 2020-11-18 JP JP2020191310A patent/JP2021054826A/ja not_active Withdrawn
-
2021
- 2021-05-17 US US17/322,486 patent/US11692040B2/en active Active
- 2021-11-03 IL IL287823A patent/IL287823A/en unknown
-
2022
- 2022-01-19 AU AU2022200323A patent/AU2022200323B2/en active Active
- 2022-12-14 JP JP2022199466A patent/JP2023036717A/ja active Pending
-
2023
- 2023-06-26 US US18/341,202 patent/US12275793B2/en active Active
-
2024
- 2024-07-02 AU AU2024204572A patent/AU2024204572A1/en active Pending
-
2025
- 2025-01-16 JP JP2025006366A patent/JP2025081304A/ja active Pending
- 2025-01-17 US US19/030,443 patent/US20250263493A1/en active Pending
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