JP2013517277A5 - - Google Patents
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- JP2013517277A5 JP2013517277A5 JP2012549047A JP2012549047A JP2013517277A5 JP 2013517277 A5 JP2013517277 A5 JP 2013517277A5 JP 2012549047 A JP2012549047 A JP 2012549047A JP 2012549047 A JP2012549047 A JP 2012549047A JP 2013517277 A5 JP2013517277 A5 JP 2013517277A5
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- JP
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- Prior art keywords
- seq
- antibody
- heavy chain
- light chain
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- 101001033233 Homo sapiens Interleukin-10 Proteins 0.000 claims 1
- 101001019598 Homo sapiens Interleukin-17 receptor A Proteins 0.000 claims 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 1
- 229930182821 L-proline Natural products 0.000 claims 1
- 229920001213 Polysorbate 20 Polymers 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 229930195712 glutamate Natural products 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 1
- 229940068977 polysorbate 20 Drugs 0.000 claims 1
- 229960002429 proline Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29538710P | 2010-01-15 | 2010-01-15 | |
| US61/295,387 | 2010-01-15 | ||
| US42205910P | 2010-12-10 | 2010-12-10 | |
| US61/422,059 | 2010-12-10 | ||
| PCT/US2011/020985 WO2011088120A1 (en) | 2010-01-15 | 2011-01-12 | Antibody formulation and therapeutic regimens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247218A Division JP2015052017A (ja) | 2010-01-15 | 2014-12-05 | 抗体製剤及び治療レジメン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013517277A JP2013517277A (ja) | 2013-05-16 |
| JP2013517277A5 true JP2013517277A5 (enExample) | 2014-02-27 |
| JP5743234B2 JP5743234B2 (ja) | 2015-07-01 |
Family
ID=43858045
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012549047A Active JP5743234B2 (ja) | 2010-01-15 | 2011-01-12 | 抗体製剤及び治療レジメン |
| JP2014247218A Pending JP2015052017A (ja) | 2010-01-15 | 2014-12-05 | 抗体製剤及び治療レジメン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247218A Pending JP2015052017A (ja) | 2010-01-15 | 2014-12-05 | 抗体製剤及び治療レジメン |
Country Status (38)
Families Citing this family (36)
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| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| DK2523688T3 (en) | 2010-01-15 | 2017-12-04 | Kirin-Amgen Inc | ANTIBODY FORMULATION AND THERAPEUTIC REGIMENS |
| ES2716088T3 (es) | 2010-02-04 | 2019-06-10 | Csl Behring Ag | Preparado de inmunoglobulina |
| NZ603570A (en) | 2010-05-20 | 2014-12-24 | Ablynx Nv | Biological materials related to her3 |
| EP2619226B1 (en) * | 2010-09-22 | 2018-09-12 | Amgen Inc. | Carrier immunoglobulins and uses thereof |
| JP2014516924A (ja) * | 2011-04-07 | 2014-07-17 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 粘度が低減された処方物 |
| UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| JOP20200043A1 (ar) * | 2011-05-10 | 2017-06-16 | Amgen Inc | طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول |
| US20140234330A1 (en) * | 2011-07-22 | 2014-08-21 | Amgen Inc. | Il-17 receptor a is required for il-17c biology |
| EP2782599B1 (en) * | 2011-11-23 | 2019-10-16 | Amgen Inc. | Administration of alpha4beta7 hetero-dimer-specific antibody |
| SG11201404491XA (en) * | 2012-03-07 | 2014-09-26 | Lilly Co Eli | Il-17 antibody formulation |
| JP6681711B2 (ja) | 2012-05-14 | 2020-04-15 | ノヴォ ノルディスク アー／エス | 安定化されたタンパク質溶液 |
| WO2014149425A1 (en) | 2013-03-15 | 2014-09-25 | Amgen Inc. | Methods for treating psoriasis using an anti-il-23 antibody |
| AP2015008801A0 (en) | 2013-03-15 | 2015-10-31 | Amgen Inc | Methods for treating crohn's disease using an anti-il23 antibody |
| AU2015241373B2 (en) * | 2014-03-31 | 2020-11-05 | Amgen K-A, Inc. | Methods of treating nail and scalp psoriasis |
| CA2949237C (en) | 2014-05-16 | 2022-08-23 | Amgen Inc. | Assay for detecting th1 and th2 cell populations |
| MY186840A (en) | 2014-08-26 | 2021-08-25 | Amgen K A Inc | Method for treating psoriasis patient which received anti-tnf-alpha antibody therapy |
| WO2016039319A1 (ja) * | 2014-09-10 | 2016-03-17 | 日油株式会社 | 蛋白質吸着抑制剤及び蛋白質吸着抑制方法 |
| CN106999588A (zh) | 2014-12-03 | 2017-08-01 | 瑞士杰特贝林生物制品有限公司 | 具有增加的稳定性的包含免疫球蛋白的药物产品 |
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| AU2016323579A1 (en) | 2015-09-17 | 2018-04-05 | Amgen Inc. | Prediction of clinical response to IL23-antagonists using IL23 pathway biomarkers |
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| CA3007098A1 (en) | 2015-12-22 | 2017-06-29 | Amgen Inc | Ccl20 as a predictor of clinical response to il23-antagonists |
| US10222674B2 (en) | 2016-04-19 | 2019-03-05 | Sage Electrochromics, Inc. | Electrochromic device including a transparent conductive oxide layer and a bus bar and a process of forming the same |
| GB201612043D0 (en) * | 2016-07-11 | 2016-08-24 | Crescendo Biologics Ltd | Composition for treatment of disorders |
| CA2974531A1 (en) * | 2017-07-26 | 2019-01-26 | Michael Giroux | Safety anchor and roof vent |
| GB201719447D0 (en) | 2017-11-23 | 2018-01-10 | Ucb Biopharma Sprl | Pharmaceutical composition |
| KR20210032441A (ko) | 2018-07-13 | 2021-03-24 | 아스트라제네카 콜라보레이션 벤처스, 엘엘씨 | 브라지쿠맙을 이용한 궤양성 대장염의 치료 |
| PE20212185A1 (es) | 2019-02-18 | 2021-11-11 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos |
| WO2021050563A1 (en) * | 2019-09-09 | 2021-03-18 | The Rockefeller University | Antibody treatment for lesional tissue of hidradenitis suppurativa |
| US20220380449A1 (en) * | 2019-09-11 | 2022-12-01 | Bausch Health Ireland Limited | Methods of treating nonalcoholic fatty liver disease (nafld) using il-17ra antibody |
| KR20220143699A (ko) * | 2020-02-18 | 2022-10-25 | 암젠 인크 | 인간 항-tslp 항체 제형 및 이의 이용 방법 |
| CN112891530B (zh) * | 2020-06-19 | 2021-08-24 | 北京东方百泰生物科技股份有限公司 | 一种抗il-17ra单克隆抗体的注射制剂 |
| JP2024518536A (ja) * | 2021-05-12 | 2024-05-01 | アナプティスバイオ インコーポレイティッド | 抗体組成物 |
| EP4537345A1 (en) * | 2022-06-06 | 2025-04-16 | Fusion Pharmaceuticals Inc. | Methods of dosing therapeutic agents |
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-
2011
- 2011-01-12 DK DK11705713.3T patent/DK2523688T3/en active
- 2011-01-12 MA MA35124A patent/MA33989B1/fr unknown
- 2011-01-12 SI SI201131792T patent/SI3295957T1/sl unknown
- 2011-01-12 EP EP19189613.3A patent/EP3632466A1/en not_active Withdrawn
- 2011-01-12 CA CA2787128A patent/CA2787128C/en active Active
- 2011-01-12 SI SI201131350T patent/SI2523688T1/en unknown
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