MA50435A - Anticorps anti-ligand anti-cd40 thérapeutiques - Google Patents

Anticorps anti-ligand anti-cd40 thérapeutiques

Info

Publication number
MA50435A
MA50435A MA050435A MA50435A MA50435A MA 50435 A MA50435 A MA 50435A MA 050435 A MA050435 A MA 050435A MA 50435 A MA50435 A MA 50435A MA 50435 A MA50435 A MA 50435A
Authority
MA
Morocco
Prior art keywords
antibodies
ligand
therapeutic
therapeutic anti
ligand anti
Prior art date
Application number
MA050435A
Other languages
English (en)
Inventor
Alexey Lugovskoy
Original Assignee
Als Therapy Development Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Als Therapy Development Inst filed Critical Als Therapy Development Inst
Publication of MA50435A publication Critical patent/MA50435A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
MA050435A 2017-05-24 2018-05-23 Anticorps anti-ligand anti-cd40 thérapeutiques MA50435A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762510471P 2017-05-24 2017-05-24

Publications (1)

Publication Number Publication Date
MA50435A true MA50435A (fr) 2020-09-02

Family

ID=63592816

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050435A MA50435A (fr) 2017-05-24 2018-05-23 Anticorps anti-ligand anti-cd40 thérapeutiques

Country Status (14)

Country Link
US (2) US11384152B2 (fr)
EP (1) EP3630843A2 (fr)
JP (2) JP2020521745A (fr)
KR (1) KR20200010294A (fr)
CN (2) CN117843789A (fr)
AU (1) AU2018271915A1 (fr)
CA (1) CA3063730A1 (fr)
GB (1) GB2578037A (fr)
IL (2) IL309444A (fr)
MA (1) MA50435A (fr)
MX (1) MX2023004314A (fr)
RU (2) RU2022108410A (fr)
SG (1) SG10202111207TA (fr)
WO (1) WO2018217918A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA41459A (fr) 2015-02-03 2017-12-12 Als Therapy Development Inst Anticorps anti-cd40l et méthodes pour traiter des maladies ou des troubles liés aux cd40l
CA3145453A1 (fr) * 2019-07-01 2021-01-07 Tonix Pharma Limited Anticorps anti-cd154 et leurs utilisations
KR20210095781A (ko) 2020-01-24 2021-08-03 주식회사 에이프릴바이오 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물
WO2023230538A2 (fr) * 2022-05-27 2023-11-30 Eledon Pharmaceuticals, Inc. Méthodes pour le traitement de la sclérose latérale amyotrophique
WO2024211211A1 (fr) 2023-04-03 2024-10-10 Regeneron Pharmaceuticals, Inc. Méthodes pour améliorer la survie d'une greffe à l'aide d'anticorps à chaîne gamma du récepteur il-2

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US5637481A (en) 1993-02-01 1997-06-10 Bristol-Myers Squibb Company Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
US5961974A (en) 1991-10-25 1999-10-05 Immunex Corporation Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
US5962406A (en) 1991-10-25 1999-10-05 Immunex Corporation Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
US5474771A (en) 1991-11-15 1995-12-12 The Trustees Of Columbia University In The City Of New York Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same
US7070777B1 (en) 1991-11-15 2006-07-04 The Trustees Of Columbia University In The City Of New York Method for inhibiting inflammation with an antibody that binds the 5C8 protein
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US5833987A (en) 1995-06-07 1998-11-10 Trustees Of Dartmouth College Treatment of T cell mediated autoimmune disorders
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
US6340459B1 (en) 1995-12-01 2002-01-22 The Trustees Of Columbia University In The City Of New York Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients
WO1998030240A1 (fr) 1997-01-10 1998-07-16 Biogen, Inc. Traitement de la nephropathie lupique a l'aide des composes anti-cd40l
EA002549B1 (ru) 1997-05-17 2002-06-27 Байоджен, Инк. Применение блокатора связывания cd40:cd154 для предотвращения противоадаптивных иммунных реакций, в частности отторжения трансплантата
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EP1664116A4 (fr) 2003-08-22 2009-06-03 Biogen Idec Inc Anticorps ameliores possedant une fonction d'effecteur modifiee et procedes de fabrication associes
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Also Published As

Publication number Publication date
CN110662768A (zh) 2020-01-07
RU2019143098A (ru) 2021-06-24
WO2018217918A3 (fr) 2019-01-17
US20200223932A1 (en) 2020-07-16
JP2020521745A (ja) 2020-07-27
MX2023004314A (es) 2023-05-04
IL309444A (en) 2024-02-01
CA3063730A1 (fr) 2018-11-29
RU2019143098A3 (fr) 2021-09-20
EP3630843A2 (fr) 2020-04-08
AU2018271915A1 (en) 2019-11-28
US20230048260A1 (en) 2023-02-16
SG10202111207TA (en) 2021-11-29
KR20200010294A (ko) 2020-01-30
US11384152B2 (en) 2022-07-12
RU2022108410A (ru) 2022-04-05
JP2023065390A (ja) 2023-05-12
CN110662768B (zh) 2024-01-30
IL270729A (en) 2020-01-30
GB2578037A (en) 2020-04-15
CN117843789A (zh) 2024-04-09
WO2018217918A2 (fr) 2018-11-29
RU2770209C2 (ru) 2022-04-14
GB201918703D0 (en) 2020-01-29

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