JP2018503726A5 - - Google Patents
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- Publication number
- JP2018503726A5 JP2018503726A5 JP2017539328A JP2017539328A JP2018503726A5 JP 2018503726 A5 JP2018503726 A5 JP 2018503726A5 JP 2017539328 A JP2017539328 A JP 2017539328A JP 2017539328 A JP2017539328 A JP 2017539328A JP 2018503726 A5 JP2018503726 A5 JP 2018503726A5
- Authority
- JP
- Japan
- Prior art keywords
- citric acid
- carboxymethylcellulose
- weight
- carboxymethyl cellulose
- crosslinked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 39
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 21
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 19
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 18
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 18
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 18
- 238000000034 method Methods 0.000 claims 14
- 239000002245 particle Substances 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 238000001035 drying Methods 0.000 claims 5
- 239000007864 aqueous solution Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 238000004132 cross linking Methods 0.000 claims 3
- 239000002131 composite material Substances 0.000 claims 2
- 239000011246 composite particle Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 1
- 206010033307 Overweight Diseases 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000002641 glycemic effect Effects 0.000 claims 1
- 238000000227 grinding Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000036186 satiety Effects 0.000 claims 1
- 235000019627 satiety Nutrition 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562109392P | 2015-01-29 | 2015-01-29 | |
| US62/109,392 | 2015-01-29 | ||
| PCT/US2016/015669 WO2016123490A1 (en) | 2015-01-29 | 2016-01-29 | Method for producing hydrogels coupling high elastic modulus and absorbance |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021033428A Division JP2021091919A (ja) | 2015-01-29 | 2021-03-03 | 高弾性率および高吸収度を併せ持つヒドロゲルの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018503726A JP2018503726A (ja) | 2018-02-08 |
| JP2018503726A5 true JP2018503726A5 (https=) | 2019-03-07 |
| JP6847841B2 JP6847841B2 (ja) | 2021-03-24 |
Family
ID=56544392
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017539328A Active JP6847841B2 (ja) | 2015-01-29 | 2016-01-29 | 高弾性率および高吸収度を併せ持つヒドロゲルの製造方法 |
| JP2021033428A Pending JP2021091919A (ja) | 2015-01-29 | 2021-03-03 | 高弾性率および高吸収度を併せ持つヒドロゲルの製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021033428A Pending JP2021091919A (ja) | 2015-01-29 | 2021-03-03 | 高弾性率および高吸収度を併せ持つヒドロゲルの製造方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US10179824B2 (https=) |
| EP (2) | EP3250612B1 (https=) |
| JP (2) | JP6847841B2 (https=) |
| KR (2) | KR102849940B1 (https=) |
| CN (1) | CN107250164B (https=) |
| AU (1) | AU2016211329B2 (https=) |
| BR (1) | BR112017016200B1 (https=) |
| CA (1) | CA2974967C (https=) |
| ES (1) | ES2847776T3 (https=) |
| MX (1) | MX2017009805A (https=) |
| PL (1) | PL3250612T3 (https=) |
| RU (1) | RU2709361C2 (https=) |
| WO (1) | WO2016123490A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2010001629A (es) * | 2007-08-10 | 2010-08-09 | Alessandro Sannino | Hidrogeles de polimero y metodos de preparacion de los mismos. |
| EP2717685B1 (en) | 2011-06-07 | 2018-08-22 | Gelesis LLC | Method for producing hydrogels |
| CA2950482C (en) | 2014-06-20 | 2022-12-06 | Gelesis, Llc | Methods for treating overweight or obesity |
| CA2974967C (en) | 2015-01-29 | 2023-06-27 | Gelesis Llc | Method for producing hydrogels coupling high elastic modulus and absorbance |
| JP7132128B2 (ja) * | 2016-04-25 | 2022-09-06 | ジェレシス，エルエルシー | 便秘の治療方法 |
| BR112019006328B1 (pt) * | 2016-09-30 | 2022-07-19 | Aquabank Australia Pty Ltd | Método para sustentar o crescimento de uma cultura agrícola |
| AU2018248418A1 (en) * | 2017-04-05 | 2019-11-21 | Gelesis, Llc | Improved superabsorbent materials and methods of production thereof |
| AU2018251210B2 (en) * | 2017-04-14 | 2025-01-23 | Gelesis S.r.l. | Compositions and methods for treating or preventing gut permeability-related disorders |
| US11918602B2 (en) | 2018-08-10 | 2024-03-05 | Simeon Investment, Inc. | Methods for reducing cholesterol with superabsorbent materials |
| US11925660B2 (en) | 2018-08-10 | 2024-03-12 | Simeon Investment, Inc. | Treatment for obesity with superabsorbent materials |
| US12285738B2 (en) | 2018-08-10 | 2025-04-29 | Simeon Investment, Inc. | Modulation of glucose bioaccessibility with superabsorbent materials |
| WO2021067076A1 (en) * | 2019-10-01 | 2021-04-08 | Brillian Pharma Inc. | Methods for treating or preventing obesity and body weight management |
| FR3105729B1 (fr) * | 2019-12-31 | 2023-07-21 | Mrs Biotech | Composition pour la gestion du poids d’un sujet |
| RU2743941C1 (ru) * | 2020-07-29 | 2021-03-01 | Федеральное государственное бюджетное учреждение науки Институт химии Дальневосточного отделения Российской академии наук (ИХ ДВО РАН) | Способ получения биополимерного гидрогеля |
| WO2022203606A1 (en) * | 2021-03-23 | 2022-09-29 | The Chloroplast Pte. Ltd. | Superabsorbent hydrogels |
| EP4335890A4 (en) * | 2021-07-09 | 2024-10-02 | Lg Chem, Ltd. | Biodegradable super absorbent polymer and preparation method thereof |
| CN114409929B (zh) * | 2022-02-07 | 2024-07-05 | 南京易亨制药有限公司 | 一种聚合物水凝胶及其制备方法和其应用 |
| CN114409928B (zh) * | 2022-02-07 | 2024-04-09 | 南京易亨制药有限公司 | 一种高弹性模量的聚合物水凝胶及其制备方法和其应用 |
| CN114702734A (zh) * | 2022-04-08 | 2022-07-05 | 重庆师范大学 | 一种纤维素醚类凝胶及其制备方法和应用 |
| WO2024013649A2 (en) * | 2022-07-11 | 2024-01-18 | Glycemic Shield | Nutrition related swellable item |
| CN115317630A (zh) * | 2022-10-14 | 2022-11-11 | 山东百多安医疗器械股份有限公司 | 一种用于超声的胃肠助显胶囊及其制备方法 |
| CN116210894A (zh) * | 2022-11-18 | 2023-06-06 | 西北大学 | 一种饱腹型水凝胶的制备方法及应用 |
| CN116807980B (zh) * | 2023-07-10 | 2024-11-05 | 橡果美健实业投资股份有限公司 | 用于肥胖干预的胃内占容水凝胶颗粒的制备方法及应用 |
| CN117159788A (zh) * | 2023-09-15 | 2023-12-05 | 江西博恩锐尔生物科技有限公司 | 一种鼻用抗过敏粉末敷料及其制备方法 |
| CN121532449A (zh) * | 2023-10-08 | 2026-02-13 | 长春金赛药业有限责任公司 | 一种氨基酸交联多糖聚合物、水凝胶及其制备方法 |
| CN119912709B (zh) * | 2025-01-21 | 2025-10-14 | 江苏创健医疗科技股份有限公司 | 一种高吸收性水凝胶及其制备方法与应用 |
Family Cites Families (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE212969C (https=) | ||||
| US3526048A (en) | 1967-06-07 | 1970-09-01 | Us Agriculture | Cellulose fibers cross-linked and esterified with polycarboxylic acids |
| JPS5885813A (ja) | 1981-11-17 | 1983-05-23 | Toyo Jozo Co Ltd | 吸収性良好な製剤 |
| DD212969A1 (de) | 1982-12-30 | 1984-08-29 | Adw Inst Polymerenchemie | Verfahren zur modifizierung von carboxymethylcellulose |
| JPS62141001A (ja) | 1985-12-13 | 1987-06-24 | Dai Ichi Kogyo Seiyaku Co Ltd | 水不溶性のカルボキシアルキルセルロ−ス・アルカリ金属塩の製造方法 |
| US5047513A (en) | 1986-07-10 | 1991-09-10 | Hoffmann-La Roche Inc. | Metal chelate resins |
| IT1219587B (it) | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| US5137537A (en) | 1989-11-07 | 1992-08-11 | The Procter & Gamble Cellulose Company | Absorbent structure containing individualized, polycarboxylic acid crosslinked wood pulp cellulose fibers |
| WO1991016057A1 (en) | 1990-04-18 | 1991-10-31 | University Of Utah | COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING |
| US5247072A (en) | 1991-10-25 | 1993-09-21 | Kimberly-Clark Corporation | Carboxyalkyl polysaccharides having improved absorbent properties and process for the preparation thereof |
| US5550189A (en) | 1992-04-17 | 1996-08-27 | Kimberly-Clark Corporation | Modified polysaccharides having improved absorbent properties and process for the preparation thereof |
| SK281042B6 (sk) | 1992-09-18 | 2000-11-07 | Yamanouchi Pharmaceutical Co., Ltd | Prípravok hydrogélového typu s ustáleným uvoľňovaním |
| AU681076B2 (en) | 1993-05-03 | 1997-08-21 | Chemische Fabrik Stockhausen Gmbh | Polymer composition, absorbent material composition, their production and their use |
| RU2146270C1 (ru) | 1993-05-03 | 2000-03-10 | Хемише Фабрик Штокхаузен ГмбХ | Полимерные композиции и способы их получения |
| JP3274550B2 (ja) | 1993-08-03 | 2002-04-15 | 株式会社日本触媒 | 吸水材の製法 |
| KR100391244B1 (ko) | 1994-03-18 | 2003-12-01 | 더 프록터 앤드 갬블 캄파니 | 개별화된 폴리카복실산 가교결합 셀룰로즈섬유의 제조방법 |
| AU3274895A (en) | 1994-07-18 | 1996-02-16 | Gel Sciences, Inc. | Novel polymer gel networks and methods of use |
| BR9509869A (pt) | 1994-12-09 | 1997-11-25 | Procter & Gamble | Composto absorvente e processo para produzir esse composto absorvente |
| US6060534A (en) | 1996-07-11 | 2000-05-09 | Scimed Life Systems, Inc. | Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties |
| US20010006677A1 (en) | 1996-10-29 | 2001-07-05 | Mcginity James W. | Effervescence polymeric film drug delivery system |
| DE19654745C5 (de) | 1996-12-30 | 2004-01-22 | Lechner, M.D., Prof. Dr. | Biologisch abbaubares Absorptionsmittel, dessen Herstellung und Verwendung |
| US6271278B1 (en) | 1997-05-13 | 2001-08-07 | Purdue Research Foundation | Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties |
| AU3561697A (en) | 1997-06-24 | 1999-01-04 | Sca Molnlycke Ab | Absorbent polymer material based on renewable starting materials |
| CO5070628A1 (es) | 1997-11-25 | 2001-08-28 | Kimberly Clark Co | Espuma absorbente que comprende un polimero, el producto absorbente que la comprende y el proceso para su preparacion |
| AU1908500A (en) | 1998-11-30 | 2000-06-19 | Hercules Incorporated | Controlled release carbohydrate embedded in a crosslinked polysaccharide |
| ATE483480T1 (de) | 1998-12-16 | 2010-10-15 | Tno | Saure superabsorbierende polysaccharide |
| US6471824B1 (en) | 1998-12-29 | 2002-10-29 | Weyerhaeuser Company | Carboxylated cellulosic fibers |
| US6686464B1 (en) | 1999-04-26 | 2004-02-03 | Bki Holding Corporation | Cellulose ethers and method of preparing the same |
| US6867346B1 (en) | 1999-09-21 | 2005-03-15 | Weyerhaeuser Company | Absorbent composite having fibrous bands |
| EP1134232A1 (en) | 2000-03-16 | 2001-09-19 | SCA Hygiene Products AB | Polysaccharide-based superabsorbent film |
| RU2002133855A (ru) | 2000-05-15 | 2004-06-27 | Кимберли-Кларк Ворлдвайд, Инк. (Us) | Полисахаридный абсорбент и способ его получения |
| US8263112B2 (en) | 2000-11-20 | 2012-09-11 | Sorbent Therapeutics, Inc. | In vivo use of water absorbent polymers |
| DE10125599A1 (de) | 2001-05-25 | 2002-11-28 | Stockhausen Chem Fab Gmbh | Superabsorber, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP1425320B1 (de) | 2001-06-28 | 2006-09-20 | Basf Aktiengesellschaft | Saure hochquellfähige hydrogele |
| WO2003089506A1 (en) | 2002-04-22 | 2003-10-30 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
| JP4132993B2 (ja) | 2002-06-03 | 2008-08-13 | 住友精化株式会社 | 吸水性樹脂およびその製造方法 |
| US7648619B2 (en) | 2002-06-04 | 2010-01-19 | Industrial Technology Research | Hydrogel-driven micropump |
| US20040192582A1 (en) | 2002-12-19 | 2004-09-30 | Burnett Daniel R. | Ingestible formulations for transient, noninvasive reduction of gastric volume |
| NL1023257C2 (nl) | 2003-04-24 | 2004-10-27 | Tno | Vochtwerende bekledingslaag voor voedingsmiddelen. |
| WO2005036971A1 (en) | 2003-10-16 | 2005-04-28 | Techcom Group, Llc | Reduced digestible carbohydrate food having reduced blood glucose response |
| US8128958B2 (en) | 2003-11-10 | 2012-03-06 | Astellas Pharma Inc. | Sustained release pharmaceutical composition |
| US20050143571A1 (en) | 2003-12-30 | 2005-06-30 | Weyerhaeuser Company | Method for forming individualized intrafiber crosslinked cellulosic fibers with improved brightness and color |
| KR100863870B1 (ko) | 2004-06-21 | 2008-10-15 | 에보닉 스톡하우젠 게엠베하 | 수분 흡수성 다당류 및 이의 제조방법 |
| WO2006056079A1 (en) | 2004-11-26 | 2006-06-01 | Medicure International Inc. | Formulations of pyridoxal -5'-phosphate and methods of preparation |
| WO2006061087A1 (en) | 2004-12-08 | 2006-06-15 | Unilever Plc | Satiety enhancing food product and a method for manufacturing such |
| US20060142478A1 (en) | 2004-12-29 | 2006-06-29 | Mengkui Luo | Carboxyalkyl cellulose polymer network |
| US20060142561A1 (en) | 2004-12-29 | 2006-06-29 | Mengkui Luo | Carboxyalkyl cellulose |
| US7300965B2 (en) | 2004-12-29 | 2007-11-27 | Weyerhaeuser Company | Mixed polymer network |
| US20060142480A1 (en) | 2004-12-29 | 2006-06-29 | Mengkui Luo | Method of making carboxyalkyl cellulose polymer network |
| ITTO20040918A1 (it) | 2004-12-29 | 2005-03-29 | Luigi Ambrosio | Idrogel polimerici superassorbenti biodegradabili e procedimento per la loro preparazione |
| FR2882366B1 (fr) | 2005-02-18 | 2008-04-18 | Coletica Sa | Polymere reticule de carbohydrate, notamment a base de polysaccharides et/ou de polyols |
| JP2009531462A (ja) | 2006-03-28 | 2009-09-03 | ジェレシス， インク． | 性能向上のためのポリマ材料と他の物質との併用 |
| US8795709B2 (en) * | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
| RU2008142840A (ru) | 2006-03-30 | 2010-05-10 | Джелесис, Инк. (Us) | Сополимер стирола и малеинового ангидрида/кислоты (варианты), изделие на его основе, способ получения сополимера стирола и малеинового ангидрида/кислоты |
| AU2007233106A1 (en) | 2006-03-30 | 2007-10-11 | Exotech Bio Solutions Ltd. | Styrene-maleic anhydride copolymers for bioapplications and their preparation |
| JP4288618B2 (ja) * | 2006-09-15 | 2009-07-01 | 独立行政法人 日本原子力研究開発機構 | カルボキシメチルセルロースゲルの製造方法 |
| GB2445818B8 (en) | 2006-09-15 | 2011-06-22 | Japan Atomic Energy Agency | Preparation of gels derived from carboxymethyl cellulose alkali metal salt |
| US20080147026A1 (en) | 2006-12-15 | 2008-06-19 | Jian Qin | Absorbent fiber with a low absorbent capacity and slow absorption rate |
| JP2008195649A (ja) | 2007-02-13 | 2008-08-28 | Daicel Chem Ind Ltd | 害虫防除用ベイト剤及びその製造方法 |
| EP2121186B1 (fr) | 2007-03-05 | 2019-10-30 | Rhodia Opérations | Procede de suivi de la cristallisation d'une substance |
| JP2008285611A (ja) * | 2007-05-18 | 2008-11-27 | Daicel Chem Ind Ltd | 架橋ゲルの製造方法及びその架橋ゲル |
| MX2010001629A (es) | 2007-08-10 | 2010-08-09 | Alessandro Sannino | Hidrogeles de polimero y metodos de preparacion de los mismos. |
| US8039683B2 (en) | 2007-10-15 | 2011-10-18 | Kimberly-Clark Worldwide, Inc. | Absorbent composites having improved fluid wicking and web integrity |
| US9345809B2 (en) | 2007-11-28 | 2016-05-24 | Fziomed, Inc. | Carboxymethylcellulose polyethylene glycol compositions for medical uses |
| KR101932616B1 (ko) * | 2008-11-18 | 2018-12-27 | 젤레시스 엘엘씨 | 체중 관리 및 혈당 조절 개선을 위한 방법 및 조성물 |
| EP2717685B1 (en) * | 2011-06-07 | 2018-08-22 | Gelesis LLC | Method for producing hydrogels |
| CA2812246A1 (en) * | 2012-04-11 | 2013-10-11 | John P. Sheeran | Water blocking in explosive compositions |
| RU2015121805A (ru) * | 2012-11-09 | 2017-01-10 | Геркулес Инкорпорейтед | Готовые к употреблению составы для заделки швов, в которых используется неравномерно замещенная карбоксиметилцеллюлоза |
| CA2950482C (en) | 2014-06-20 | 2022-12-06 | Gelesis, Llc | Methods for treating overweight or obesity |
| CA2974967C (en) | 2015-01-29 | 2023-06-27 | Gelesis Llc | Method for producing hydrogels coupling high elastic modulus and absorbance |
| JP7132128B2 (ja) | 2016-04-25 | 2022-09-06 | ジェレシス，エルエルシー | 便秘の治療方法 |
-
2016
- 2016-01-29 CA CA2974967A patent/CA2974967C/en active Active
- 2016-01-29 MX MX2017009805A patent/MX2017009805A/es unknown
- 2016-01-29 KR KR1020247025438A patent/KR102849940B1/ko active Active
- 2016-01-29 RU RU2017129508A patent/RU2709361C2/ru active
- 2016-01-29 US US15/010,626 patent/US10179824B2/en active Active
- 2016-01-29 WO PCT/US2016/015669 patent/WO2016123490A1/en not_active Ceased
- 2016-01-29 KR KR1020177023170A patent/KR20170109587A/ko not_active Ceased
- 2016-01-29 CN CN201680011075.7A patent/CN107250164B/zh active Active
- 2016-01-29 ES ES16744185T patent/ES2847776T3/es active Active
- 2016-01-29 AU AU2016211329A patent/AU2016211329B2/en active Active
- 2016-01-29 EP EP16744185.6A patent/EP3250612B1/en active Active
- 2016-01-29 PL PL16744185T patent/PL3250612T3/pl unknown
- 2016-01-29 BR BR112017016200-8A patent/BR112017016200B1/pt not_active IP Right Cessation
- 2016-01-29 EP EP20209935.4A patent/EP3872098A1/en not_active Withdrawn
- 2016-01-29 JP JP2017539328A patent/JP6847841B2/ja active Active
-
2018
- 2018-12-14 US US16/220,598 patent/US10584183B2/en active Active
-
2020
- 2020-03-09 US US16/812,767 patent/US11130824B2/en active Active
-
2021
- 2021-03-03 JP JP2021033428A patent/JP2021091919A/ja active Pending
- 2021-09-21 US US17/480,707 patent/US20220073652A1/en not_active Abandoned
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