BR112017016200B1 - Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica - Google Patents

Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica Download PDF

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Publication number
BR112017016200B1
BR112017016200B1 BR112017016200-8A BR112017016200A BR112017016200B1 BR 112017016200 B1 BR112017016200 B1 BR 112017016200B1 BR 112017016200 A BR112017016200 A BR 112017016200A BR 112017016200 B1 BR112017016200 B1 BR 112017016200B1
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BR
Brazil
Prior art keywords
carboxymethylcellulose
citric acid
weight
cross
water
Prior art date
Application number
BR112017016200-8A
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English (en)
Portuguese (pt)
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BR112017016200A2 (pt
BR112017016200A8 (pt
Inventor
Alessandro Sannino
Christian Demitri
Yishai Zohar
Eyal S. Ron
Barry J. Hand
Cosimo Saponaro
Original Assignee
Gelesis, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelesis, Llc filed Critical Gelesis, Llc
Publication of BR112017016200A2 publication Critical patent/BR112017016200A2/pt
Publication of BR112017016200A8 publication Critical patent/BR112017016200A8/pt
Publication of BR112017016200B1 publication Critical patent/BR112017016200B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112017016200-8A 2015-01-29 2016-01-29 Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica BR112017016200B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562109392P 2015-01-29 2015-01-29
US62/109,392 2015-01-29
PCT/US2016/015669 WO2016123490A1 (en) 2015-01-29 2016-01-29 Method for producing hydrogels coupling high elastic modulus and absorbance

Publications (3)

Publication Number Publication Date
BR112017016200A2 BR112017016200A2 (pt) 2018-03-27
BR112017016200A8 BR112017016200A8 (pt) 2022-08-30
BR112017016200B1 true BR112017016200B1 (pt) 2022-09-20

Family

ID=56544392

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017016200-8A BR112017016200B1 (pt) 2015-01-29 2016-01-29 Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica

Country Status (13)

Country Link
US (4) US10179824B2 (https=)
EP (2) EP3872098A1 (https=)
JP (2) JP6847841B2 (https=)
KR (2) KR102849940B1 (https=)
CN (1) CN107250164B (https=)
AU (1) AU2016211329B2 (https=)
BR (1) BR112017016200B1 (https=)
CA (1) CA2974967C (https=)
ES (1) ES2847776T3 (https=)
MX (1) MX2017009805A (https=)
PL (1) PL3250612T3 (https=)
RU (1) RU2709361C2 (https=)
WO (1) WO2016123490A1 (https=)

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US9855294B2 (en) 2014-06-20 2018-01-02 Gelesis, Llc Methods for treating overweight or obesity
CN107250164B (zh) 2015-01-29 2023-01-31 吉莱斯公司 用于制造结合高弹性模量和吸收性的水凝胶的方法
CN109562069B (zh) * 2016-04-25 2022-06-03 吉莱斯公司 治疗便秘的方法
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US12285738B2 (en) 2018-08-10 2025-04-29 Simeon Investment, Inc. Modulation of glucose bioaccessibility with superabsorbent materials
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JP2022550457A (ja) * 2019-10-01 2022-12-01 ブリリアン・ファーマ・インコーポレイテッド 肥満の処置又は防止及び体重管理の方法
FR3105729B1 (fr) * 2019-12-31 2023-07-21 Mrs Biotech Composition pour la gestion du poids d’un sujet
RU2743941C1 (ru) * 2020-07-29 2021-03-01 Федеральное государственное бюджетное учреждение науки Институт химии Дальневосточного отделения Российской академии наук (ИХ ДВО РАН) Способ получения биополимерного гидрогеля
EP4314086A4 (en) * 2021-03-23 2025-02-26 Junion Labs Pte. Ltd. SUPERABSORBENT HYDROGELS
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CN114409929B (zh) * 2022-02-07 2024-07-05 南京易亨制药有限公司 一种聚合物水凝胶及其制备方法和其应用
CN114409928B (zh) * 2022-02-07 2024-04-09 南京易亨制药有限公司 一种高弹性模量的聚合物水凝胶及其制备方法和其应用
CN114702734A (zh) * 2022-04-08 2022-07-05 重庆师范大学 一种纤维素醚类凝胶及其制备方法和应用
WO2024013649A2 (en) * 2022-07-11 2024-01-18 Glycemic Shield Nutrition related swellable item
CN115317630A (zh) * 2022-10-14 2022-11-11 山东百多安医疗器械股份有限公司 一种用于超声的胃肠助显胶囊及其制备方法
CN116210894A (zh) * 2022-11-18 2023-06-06 西北大学 一种饱腹型水凝胶的制备方法及应用
CN116807980B (zh) * 2023-07-10 2024-11-05 橡果美健实业投资股份有限公司 用于肥胖干预的胃内占容水凝胶颗粒的制备方法及应用
CN117159788A (zh) * 2023-09-15 2023-12-05 江西博恩锐尔生物科技有限公司 一种鼻用抗过敏粉末敷料及其制备方法
WO2025077637A1 (zh) * 2023-10-08 2025-04-17 重庆金赛星医疗科技有限公司 一种氨基酸交联多糖聚合物、水凝胶及其制备方法
CN119912709B (zh) * 2025-01-21 2025-10-14 江苏创健医疗科技股份有限公司 一种高吸收性水凝胶及其制备方法与应用

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Publication number Publication date
CN107250164A (zh) 2017-10-13
BR112017016200A2 (pt) 2018-03-27
EP3250612A1 (en) 2017-12-06
CN107250164B (zh) 2023-01-31
WO2016123490A1 (en) 2016-08-04
JP2018503726A (ja) 2018-02-08
MX2017009805A (es) 2018-05-07
US10584183B2 (en) 2020-03-10
AU2016211329A1 (en) 2017-08-03
BR112017016200A8 (pt) 2022-08-30
US11130824B2 (en) 2021-09-28
KR20170109587A (ko) 2017-09-29
EP3250612B1 (en) 2020-12-02
US10179824B2 (en) 2019-01-15
US20160222134A1 (en) 2016-08-04
JP6847841B2 (ja) 2021-03-24
PL3250612T3 (pl) 2021-06-14
ES2847776T3 (es) 2021-08-03
AU2016211329B2 (en) 2020-08-27
EP3872098A1 (en) 2021-09-01
RU2709361C2 (ru) 2019-12-17
JP2021091919A (ja) 2021-06-17
RU2017129508A3 (https=) 2019-06-25
US20190233545A1 (en) 2019-08-01
RU2017129508A (ru) 2019-02-28
US20220073652A1 (en) 2022-03-10
US20200277407A1 (en) 2020-09-03
KR20240122569A (ko) 2024-08-12
KR102849940B1 (ko) 2025-08-22
CA2974967A1 (en) 2016-08-04
EP3250612A4 (en) 2018-08-29
CA2974967C (en) 2023-06-27

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