BR112017016200A8 - Método para produzir hidrogéis conjugando módulo de alta elasticidade e absorvência - Google Patents

Método para produzir hidrogéis conjugando módulo de alta elasticidade e absorvência

Info

Publication number
BR112017016200A8
BR112017016200A8 BR112017016200A BR112017016200A BR112017016200A8 BR 112017016200 A8 BR112017016200 A8 BR 112017016200A8 BR 112017016200 A BR112017016200 A BR 112017016200A BR 112017016200 A BR112017016200 A BR 112017016200A BR 112017016200 A8 BR112017016200 A8 BR 112017016200A8
Authority
BR
Brazil
Prior art keywords
carboxymethyl cellulose
cross
linked carboxymethyl
conjugging
absorvance
Prior art date
Application number
BR112017016200A
Other languages
English (en)
Other versions
BR112017016200B1 (pt
BR112017016200A2 (pt
Inventor
Sannino Alessandro
Demitri Christian
Zohar Yishai
S Ron Eyal
J Hand Barry
Saponaro Cosimo
Original Assignee
Gelesis Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelesis Llc filed Critical Gelesis Llc
Publication of BR112017016200A2 publication Critical patent/BR112017016200A2/pt
Publication of BR112017016200A8 publication Critical patent/BR112017016200A8/pt
Publication of BR112017016200B1 publication Critical patent/BR112017016200B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

CARBOXIMETILCELULOSE RETICULADA, MÉTODO PARA A PRODUÇÃO E USO DA MESMA E COMPOSIÇÃO FARMACÊUTICA. A presente invenção fornece carboximetilcelulose reticulada com um módulo de alta elasticidade conjugado com alta capacidade de absorvência quando dilatado em fluídos gástricos simulados/água (1:8) e fluidos intestinais simulados. A invenção fornece ainda métodos para preparar a carboximetilcelulose reticulada, composições que compreendem a carboximetilcelulose reticulada e métodos de utilização da carboximetilcelulose reticulada, por exemplo, para tratar o excesso de peso ou a obesidade ou para aumentar o controle glicêmico.
BR112017016200-8A 2015-01-29 2016-01-29 Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica BR112017016200B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562109392P 2015-01-29 2015-01-29
US62/109,392 2015-01-29
PCT/US2016/015669 WO2016123490A1 (en) 2015-01-29 2016-01-29 Method for producing hydrogels coupling high elastic modulus and absorbance

Publications (3)

Publication Number Publication Date
BR112017016200A2 BR112017016200A2 (pt) 2018-03-27
BR112017016200A8 true BR112017016200A8 (pt) 2022-08-30
BR112017016200B1 BR112017016200B1 (pt) 2022-09-20

Family

ID=56544392

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017016200-8A BR112017016200B1 (pt) 2015-01-29 2016-01-29 Carboximetilcelulose reticulada com ácido cítrico e seu uso, método para a sua produção e composição farmacêutica

Country Status (13)

Country Link
US (4) US10179824B2 (pt)
EP (2) EP3872098A1 (pt)
JP (2) JP6847841B2 (pt)
KR (1) KR20170109587A (pt)
CN (1) CN107250164B (pt)
AU (1) AU2016211329B2 (pt)
BR (1) BR112017016200B1 (pt)
CA (1) CA2974967C (pt)
ES (1) ES2847776T3 (pt)
MX (1) MX2017009805A (pt)
PL (1) PL3250612T3 (pt)
RU (1) RU2709361C2 (pt)
WO (1) WO2016123490A1 (pt)

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WO2016123490A1 (en) 2015-01-29 2016-08-04 Gelesis Llc Method for producing hydrogels coupling high elastic modulus and absorbance
RU2745992C2 (ru) * 2016-04-25 2021-04-05 Джелесис ЭлЭлСи Способ лечения запора
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RU2743941C1 (ru) * 2020-07-29 2021-03-01 Федеральное государственное бюджетное учреждение науки Институт химии Дальневосточного отделения Российской академии наук (ИХ ДВО РАН) Способ получения биополимерного гидрогеля
CN115335412B (zh) * 2021-03-23 2024-04-23 厦门君德医药科技有限公司 超吸收性水凝胶
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CN114409928B (zh) * 2022-02-07 2024-04-09 南京易亨制药有限公司 一种高弹性模量的聚合物水凝胶及其制备方法和其应用
CN114409929A (zh) * 2022-02-07 2022-04-29 南京易亨制药有限公司 一种聚合物水凝胶及其制备方法和其应用
CN114702734A (zh) * 2022-04-08 2022-07-05 重庆师范大学 一种纤维素醚类凝胶及其制备方法和应用
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CN115317630A (zh) * 2022-10-14 2022-11-11 山东百多安医疗器械股份有限公司 一种用于超声的胃肠助显胶囊及其制备方法
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Also Published As

Publication number Publication date
KR20170109587A (ko) 2017-09-29
JP2018503726A (ja) 2018-02-08
US20200277407A1 (en) 2020-09-03
AU2016211329A1 (en) 2017-08-03
RU2017129508A (ru) 2019-02-28
US10179824B2 (en) 2019-01-15
WO2016123490A1 (en) 2016-08-04
JP6847841B2 (ja) 2021-03-24
ES2847776T3 (es) 2021-08-03
US20160222134A1 (en) 2016-08-04
RU2709361C2 (ru) 2019-12-17
US20220073652A1 (en) 2022-03-10
MX2017009805A (es) 2018-05-07
CN107250164B (zh) 2023-01-31
BR112017016200B1 (pt) 2022-09-20
US10584183B2 (en) 2020-03-10
EP3250612B1 (en) 2020-12-02
EP3872098A1 (en) 2021-09-01
US20190233545A1 (en) 2019-08-01
AU2016211329B2 (en) 2020-08-27
CA2974967C (en) 2023-06-27
CN107250164A (zh) 2017-10-13
EP3250612A1 (en) 2017-12-06
CA2974967A1 (en) 2016-08-04
JP2021091919A (ja) 2021-06-17
BR112017016200A2 (pt) 2018-03-27
RU2017129508A3 (pt) 2019-06-25
PL3250612T3 (pl) 2021-06-14
EP3250612A4 (en) 2018-08-29
US11130824B2 (en) 2021-09-28

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