BR112016023979A2 - métodos de melhora ou aceleração da recuperação física após cirurgia para fratura óssea - Google Patents

métodos de melhora ou aceleração da recuperação física após cirurgia para fratura óssea

Info

Publication number
BR112016023979A2
BR112016023979A2 BR112016023979A BR112016023979A BR112016023979A2 BR 112016023979 A2 BR112016023979 A2 BR 112016023979A2 BR 112016023979 A BR112016023979 A BR 112016023979A BR 112016023979 A BR112016023979 A BR 112016023979A BR 112016023979 A2 BR112016023979 A2 BR 112016023979A2
Authority
BR
Brazil
Prior art keywords
improving
physical recovery
methods
antibody
bone fracture
Prior art date
Application number
BR112016023979A
Other languages
English (en)
Inventor
Papanicolaou Dimitris
GOLDHAHN Jörg
Tanko Laszlo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR112016023979A2 publication Critical patent/BR112016023979A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Abstract

a descrição refere-se a usos e regimes para aceleração/melhora da recuperação física em um paciente com atrofia por desuso disparada por mobilidade reduzida devido a uma fratura de quadril e consequente cirurgia maior, que emprega uma quantidade terapeuticamente efetiva de um antagonista de miostatina, por exemplo, uma molécula de ligação de miostatina, por exemplo, um anticorpo de miostatina ou uma molécula de ligação ao receptor actrii, um anticorpo de receptor actrii, tal como o anticorpo bimagrumabe.
BR112016023979A 2014-04-24 2015-04-24 métodos de melhora ou aceleração da recuperação física após cirurgia para fratura óssea BR112016023979A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461983565P 2014-04-24 2014-04-24
PCT/IB2015/052990 WO2015162590A1 (en) 2014-04-24 2015-04-24 Methods of improving or accelerating physical recovery after surgery for hip fracture

Publications (1)

Publication Number Publication Date
BR112016023979A2 true BR112016023979A2 (pt) 2017-10-17

Family

ID=53175568

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016023979A BR112016023979A2 (pt) 2014-04-24 2015-04-24 métodos de melhora ou aceleração da recuperação física após cirurgia para fratura óssea

Country Status (17)

Country Link
US (2) US9969806B2 (pt)
EP (2) EP3134112A1 (pt)
JP (1) JP2017513882A (pt)
KR (1) KR20160147863A (pt)
CN (1) CN106456754A (pt)
AU (2) AU2015249396A1 (pt)
BR (1) BR112016023979A2 (pt)
CA (1) CA2944842A1 (pt)
CL (1) CL2016002679A1 (pt)
IL (1) IL248215A0 (pt)
MX (1) MX2016013916A (pt)
PH (1) PH12016501927A1 (pt)
RU (1) RU2016145921A (pt)
SG (1) SG11201608042RA (pt)
TW (1) TW201622746A (pt)
WO (1) WO2015162590A1 (pt)
ZA (1) ZA201606741B (pt)

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Also Published As

Publication number Publication date
CA2944842A1 (en) 2015-10-29
MX2016013916A (es) 2017-04-06
AU2015249396A1 (en) 2016-10-20
RU2016145921A (ru) 2018-05-25
SG11201608042RA (en) 2016-11-29
PH12016501927A1 (en) 2016-12-19
US9969806B2 (en) 2018-05-15
CN106456754A (zh) 2017-02-22
WO2015162590A1 (en) 2015-10-29
TW201622746A (zh) 2016-07-01
IL248215A0 (en) 2016-11-30
EP3134112A1 (en) 2017-03-01
AU2018200537A1 (en) 2018-02-15
US20170029513A1 (en) 2017-02-02
KR20160147863A (ko) 2016-12-23
EP3461495A1 (en) 2019-04-03
JP2017513882A (ja) 2017-06-01
ZA201606741B (en) 2017-09-27
RU2016145921A3 (pt) 2018-12-18
CL2016002679A1 (es) 2017-07-07
US20180230221A1 (en) 2018-08-16

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