BR112015024234A2 - composição de liberação sustentada injetável e método para o uso da mesma para tratar inflamação em articulações e dor associada com a mesma - Google Patents

composição de liberação sustentada injetável e método para o uso da mesma para tratar inflamação em articulações e dor associada com a mesma

Info

Publication number
BR112015024234A2
BR112015024234A2 BR112015024234A BR112015024234A BR112015024234A2 BR 112015024234 A2 BR112015024234 A2 BR 112015024234A2 BR 112015024234 A BR112015024234 A BR 112015024234A BR 112015024234 A BR112015024234 A BR 112015024234A BR 112015024234 A2 BR112015024234 A2 BR 112015024234A2
Authority
BR
Brazil
Prior art keywords
sustained release
pain associated
release composition
joint inflammation
injectable sustained
Prior art date
Application number
BR112015024234A
Other languages
English (en)
Other versions
BR112015024234B1 (pt
Inventor
M Malone Amanda
A Helliwell James
M Baum Marc
J Smith Thomas
Original Assignee
Eupraxia Pharmaceuticals USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eupraxia Pharmaceuticals USA LLC filed Critical Eupraxia Pharmaceuticals USA LLC
Publication of BR112015024234A2 publication Critical patent/BR112015024234A2/pt
Publication of BR112015024234B1 publication Critical patent/BR112015024234B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

resumo “composição de liberação sustentada injetável e método para o uso da mesma para tratar inflamação em articulações e dor associada com a mesma” micropartículas carregadas com corticosteroide injetáveis, composição far-macêutica das mesmas e métodos para reduzir inflamação ou dor em um comparti-mento do corpo, tal como uma articulação, um espaço epidural, um corpo vítreo de um olho, um espaço cirurgicamente criado ou um espaço adjacente a um implante, são descritos neste relatório.
BR112015024234-0A 2013-03-21 2014-03-21 Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas BR112015024234B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361804185P 2013-03-21 2013-03-21
US61/804,185 2013-03-21
PCT/US2014/031502 WO2014153541A1 (en) 2013-03-21 2014-03-21 Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith

Publications (2)

Publication Number Publication Date
BR112015024234A2 true BR112015024234A2 (pt) 2017-07-18
BR112015024234B1 BR112015024234B1 (pt) 2022-11-16

Family

ID=50686191

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015024234-0A BR112015024234B1 (pt) 2013-03-21 2014-03-21 Composição farmacêutica de liberação sustentada injetável, uso da mesma para diminuir inflamação ou controlar dor e método para formar micropartículas revestidas

Country Status (17)

Country Link
US (5) US9987233B2 (pt)
EP (2) EP2976062B1 (pt)
JP (3) JP6230691B2 (pt)
KR (2) KR102069473B1 (pt)
CN (2) CN110575445B (pt)
AU (2) AU2014235854B2 (pt)
BR (1) BR112015024234B1 (pt)
CA (1) CA2907765C (pt)
CL (1) CL2015002826A1 (pt)
HK (1) HK1219433A1 (pt)
IL (2) IL241718B (pt)
MX (1) MX2015013457A (pt)
NZ (1) NZ713029A (pt)
RU (1) RU2015144689A (pt)
SG (2) SG10201604814WA (pt)
TW (1) TWI686213B (pt)
WO (1) WO2014153541A1 (pt)

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CN110575445B (zh) 2013-03-21 2023-08-18 优普顺药物公司美国分部 可注射的持续释放组合物及其用于治疗关节炎症及相关疼痛的方法
CN107106506A (zh) * 2014-09-19 2017-08-29 优普顺药物公司 用于治疗剂的超局部化释放的可注射微粒
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
CN108883070A (zh) * 2015-07-23 2018-11-23 爱瑞制药公司 用于治疗眼病的玻璃体内药物递送系统
TW201726145A (zh) * 2015-10-13 2017-08-01 弗萊斯恩醫療公司 用於維持皮質類固醇滑液濃度之皮質類固醇調配物
ES2672993T3 (es) * 2015-10-27 2018-06-19 Eupraxia Pharmaceuticals Inc. Formulaciones de liberación sostenida de anestésicos locales
DE102016216182A1 (de) * 2016-08-29 2018-03-01 Tetec Tissue Engineering Technologies Ag Kombination, insbesondere zum Behandeln eines Knorpeldefekts
EP3595776A4 (en) * 2017-03-17 2020-09-30 Flexion Therapeutics, Inc. FLUTICASONE SUSTAINED-RELEASE FORMULATIONS AND THEIR PROCEDURES FOR USE
CA3078555A1 (en) 2017-10-06 2019-04-11 Foundry Therapeutics, Inc. Implantable depots for the controlled release of therapeutic agents
US10976461B2 (en) * 2017-10-17 2021-04-13 California Institute Of Technology Sub-surface imaging of dielectric structures and voids via narrowband electromagnetic resonance scattering
WO2019119177A1 (zh) * 2017-12-18 2019-06-27 深圳市大疆创新科技有限公司 弱目标检测方法、微波雷达传感器及无人机
JP2021524841A (ja) 2018-05-24 2021-09-16 セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー 高分子薬剤化合物の持続放出用の埋め込み型デバイス
CN111989068A (zh) 2018-05-24 2020-11-24 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
GB202000840D0 (en) 2020-01-21 2020-03-04 Cell Guidance Systems Ltd Compositions and methods
WO2024037982A1 (en) * 2022-08-16 2024-02-22 Boehringer Ingelheim International Gmbh Pharmaceutical formulations of nintedanib for intraocular use
WO2024077017A1 (en) 2022-10-04 2024-04-11 Eupraxia Pharmaceuticals Inc. Use of long-acting fluticasone propionate injectable suspensions for treating and preventing inflammations of the gastrointestinal tract

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