BR112017003346A2 - derivados de pirazolopiridina, seus usos, e composição farmacêutica - Google Patents

derivados de pirazolopiridina, seus usos, e composição farmacêutica

Info

Publication number
BR112017003346A2
BR112017003346A2 BR112017003346A BR112017003346A BR112017003346A2 BR 112017003346 A2 BR112017003346 A2 BR 112017003346A2 BR 112017003346 A BR112017003346 A BR 112017003346A BR 112017003346 A BR112017003346 A BR 112017003346A BR 112017003346 A2 BR112017003346 A2 BR 112017003346A2
Authority
BR
Brazil
Prior art keywords
pyrazolopyridine derivatives
pharmaceutical composition
pyrazolopyridine
derivatives
parasite
Prior art date
Application number
BR112017003346A
Other languages
English (en)
Other versions
BR112017003346B8 (pt
BR112017003346B1 (pt
Inventor
Popowicz Grzegorz
Emmanouilidis Leonidas
Dawidowski Maciej
Sattler Michael
Erdmann Ralf
Kalel Vishal
Schliebs Wolfgang
Original Assignee
Helmboltz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmboltz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt Gmbh filed Critical Helmboltz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt Gmbh
Publication of BR112017003346A2 publication Critical patent/BR112017003346A2/pt
Publication of BR112017003346B1 publication Critical patent/BR112017003346B1/pt
Publication of BR112017003346B8 publication Critical patent/BR112017003346B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Abstract

a presente invenção refere-se aos derivados de pirazolopiridina, que são úteis como medicamentos, composições farmacêuticas compreendendo um ou mais dos derivados de pirazolopiridina, e o uso de um ou mais dos derivados de pirazolopiridina nos métodos para o tratamento e/ou prevenção de uma doença provocada ou mediada por um parasita da família tripanosomatidae.
BR112017003346A 2014-09-08 2015-09-08 Derivados de pirazolopiridina, seus usos, e composição farmacêutica BR112017003346B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14183991.0 2014-09-08
EP14183991.0A EP2993174A1 (en) 2014-09-08 2014-09-08 Pyrazolopyridine derivatives and their use in therapy
PCT/EP2015/070513 WO2016038045A1 (en) 2014-09-08 2015-09-08 Pyrazolopyridine derivatives and their use in therapy

Publications (3)

Publication Number Publication Date
BR112017003346A2 true BR112017003346A2 (pt) 2018-11-06
BR112017003346B1 BR112017003346B1 (pt) 2023-11-07
BR112017003346B8 BR112017003346B8 (pt) 2023-11-28

Family

ID=51485526

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017003346A BR112017003346B8 (pt) 2014-09-08 2015-09-08 Derivados de pirazolopiridina, seus usos, e composição farmacêutica

Country Status (5)

Country Link
US (2) US9840504B2 (pt)
EP (2) EP2993174A1 (pt)
BR (1) BR112017003346B8 (pt)
MX (1) MX2017002816A (pt)
WO (1) WO2016038045A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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CN109476663B (zh) * 2016-05-24 2021-11-09 基因泰克公司 用于治疗癌症的吡唑并吡啶衍生物
TW201806956A (zh) * 2016-06-29 2018-03-01 諾維拉治療公司 二氮呯酮衍生物及治療ｂ型肝炎感染之方法
CN109641896B (zh) * 2016-06-29 2021-09-21 诺维拉治疗公司 二氮杂酮衍生物及其在治疗乙型肝炎感染中的用途
JOP20190060A1 (ar) * 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
JP7461104B2 (ja) * 2017-11-29 2024-04-03 中外製薬株式会社 Ｇｌｐ－１受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物
AU2018375308A1 (en) 2017-11-29 2020-06-25 The Rockefeller University Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases
GB201720064D0 (en) * 2017-12-01 2018-01-17 Univ Edinburgh Compounds
JOP20210313A1 (ar) * 2019-05-28 2023-01-30 Janssen Sciences Ireland Unlimited Co مشتقات حلقية غير متجانسة مندمجة
JP2022535208A (ja) * 2019-05-28 2022-08-05 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー 抗ウイルス剤としての縮合ヘテロ環誘導体
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
MX2022009524A (es) 2020-02-07 2023-01-11 Gasherbrum Bio Inc Agonistas heterociclicos de glp-1.
CN113264931B (zh) * 2020-02-17 2022-06-07 成都先导药物开发股份有限公司 一种1,4,6,7-四氢-5H-吡唑并[4,3-c]吡啶衍生物的制备方法
CA3220039A1 (en) 2021-06-14 2022-12-22 Jr. David St. Jean Urea derivatives which can be used to treat cancer

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Also Published As

Publication number Publication date
BR112017003346B8 (pt) 2023-11-28
EP3191484A1 (en) 2017-07-19
MX2017002816A (es) 2017-08-02
WO2016038045A1 (en) 2016-03-17
EP2993174A1 (en) 2016-03-09
US9840504B2 (en) 2017-12-12
US20180186789A1 (en) 2018-07-05
US20170247375A1 (en) 2017-08-31
US10138242B2 (en) 2018-11-27
BR112017003346B1 (pt) 2023-11-07

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: B21D 15/00 , B21D 15/04

Ipc: C07D 471/04 (2006.01), A61K 33/00 (2006.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023010013-1 PROTOCOLO 870230043341 EM 23/05/2023 16:59.

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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