BR112017024908A2 - usos terapêuticos da 4-cloroquinurenina - Google Patents
usos terapêuticos da 4-cloroquinureninaInfo
- Publication number
- BR112017024908A2 BR112017024908A2 BR112017024908A BR112017024908A BR112017024908A2 BR 112017024908 A2 BR112017024908 A2 BR 112017024908A2 BR 112017024908 A BR112017024908 A BR 112017024908A BR 112017024908 A BR112017024908 A BR 112017024908A BR 112017024908 A2 BR112017024908 A2 BR 112017024908A2
- Authority
- BR
- Brazil
- Prior art keywords
- chloroquinurenine
- therapeutic uses
- conditions
- treatment
- pharmaceutical compositions
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
composições farmacêuticas compreendendo l-4-cloroquinurenina e métodos terapêuticos associados são proporcionados para o tratamento de determinadas condições neurológicas e outras condições.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562179924P | 2015-05-22 | 2015-05-22 | |
PCT/US2016/033733 WO2016191351A1 (en) | 2015-05-22 | 2016-05-23 | Therapeutic uses of l-4-chlorokynurenine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017024908A2 true BR112017024908A2 (pt) | 2018-07-31 |
Family
ID=57393671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017024908A BR112017024908A2 (pt) | 2015-05-22 | 2016-05-23 | usos terapêuticos da 4-cloroquinurenina |
Country Status (20)
Country | Link |
---|---|
US (3) | US20180140568A1 (pt) |
EP (2) | EP4108239A1 (pt) |
JP (3) | JP2018521007A (pt) |
KR (1) | KR20180015158A (pt) |
CN (1) | CN107949379A (pt) |
AU (3) | AU2016268153B2 (pt) |
BR (1) | BR112017024908A2 (pt) |
CA (1) | CA3024783A1 (pt) |
DK (1) | DK3297619T3 (pt) |
EA (1) | EA201792571A1 (pt) |
ES (1) | ES2925274T3 (pt) |
HK (1) | HK1257800A1 (pt) |
IL (3) | IL296380A (pt) |
MX (1) | MX2017014456A (pt) |
PL (1) | PL3297619T3 (pt) |
PT (1) | PT3297619T (pt) |
SG (1) | SG10202007661XA (pt) |
SI (1) | SI3297619T1 (pt) |
WO (1) | WO2016191351A1 (pt) |
ZA (1) | ZA201707874B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210149905A (ko) | 2013-01-22 | 2021-12-09 | 비스타젠 쎄라퓨틱스, 인크. | L-4-클로로키뉴레닌의 투여형 및 치료적 용도 |
AU2020271853A1 (en) * | 2019-04-09 | 2021-11-25 | Vistagen Therapeutics, Inc. | Genetic variants associated with response to treatment of neurological disorders |
US20230181541A1 (en) * | 2020-06-24 | 2023-06-15 | Biohaven Therapeutics Ltd. | Compositions and methods for treating obsessive-compulsive disorder |
WO2022221423A1 (en) * | 2021-04-13 | 2022-10-20 | Vistagen Therapeutics, Inc. | Treatment of autoimmune anti-nmda-receptor encephalitis |
CN115677519A (zh) * | 2021-07-22 | 2023-02-03 | 立科时代(武汉)生物科技有限公司 | L-4-溴-犬尿氨酸及其在制备治疗抑郁症药物中的应用 |
WO2024011105A1 (en) * | 2022-07-05 | 2024-01-11 | Mahana Therapeutics, Inc. | Methods and systems for treating tinnitus using digital therapeutics |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5484814A (en) | 1991-02-28 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
AU2981099A (en) * | 1998-03-09 | 1999-09-27 | Trustees Of Tufts College | Treatment of compulsive behaviours in man and animals |
TW518218B (en) * | 1999-05-27 | 2003-01-21 | Merck Patent Gmbh | Pharmaceutical compositions comprising 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine or its physiologically acceptable salts for use in the treatment of sub-type anxiety disorders |
AU2002229056A1 (en) * | 2000-12-07 | 2002-06-18 | Neuromolecular Inc. | Methods for treating neuropsychiatric disorders with NMDA receptor antagonists |
US20060063802A1 (en) * | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
MX2008013130A (es) * | 2006-04-12 | 2008-11-19 | Probiodrug Ag | Inhibidores de enzima. |
CA2606658A1 (en) * | 2006-10-13 | 2008-04-13 | Mike Tyers | Compositions and methods for treating neurological disorders or damage |
WO2009061935A2 (en) * | 2007-11-06 | 2009-05-14 | Emory University | Methods of identifying safe nmda receptor antagonists |
TW201026667A (en) * | 2008-09-30 | 2010-07-16 | Merz Pharma Gmbh & Co Kgaa | Glycine b antagonists |
CN104902883A (zh) * | 2012-08-23 | 2015-09-09 | 斯图亚特·L·韦格 | 抗焦虑组合物、制剂及使用方法 |
KR20210149905A (ko) * | 2013-01-22 | 2021-12-09 | 비스타젠 쎄라퓨틱스, 인크. | L-4-클로로키뉴레닌의 투여형 및 치료적 용도 |
EP2970097B1 (en) | 2013-03-14 | 2018-10-31 | Vistagen Therapeutics, Inc. | Methods for the synthesis of chiral kynurenine compounds |
EP2970080A4 (en) | 2013-03-14 | 2017-01-18 | Vistagen Therapeutics, Inc. | Synthesis of chiral kynurenine compounds and intermediates |
-
2016
- 2016-05-23 WO PCT/US2016/033733 patent/WO2016191351A1/en active Application Filing
- 2016-05-23 EP EP22183035.9A patent/EP4108239A1/en active Pending
- 2016-05-23 CN CN201680042400.6A patent/CN107949379A/zh active Pending
- 2016-05-23 AU AU2016268153A patent/AU2016268153B2/en active Active
- 2016-05-23 ES ES16800590T patent/ES2925274T3/es active Active
- 2016-05-23 EA EA201792571A patent/EA201792571A1/ru unknown
- 2016-05-23 SG SG10202007661XA patent/SG10202007661XA/en unknown
- 2016-05-23 DK DK16800590.8T patent/DK3297619T3/da active
- 2016-05-23 CA CA3024783A patent/CA3024783A1/en active Pending
- 2016-05-23 KR KR1020177036471A patent/KR20180015158A/ko not_active Application Discontinuation
- 2016-05-23 BR BR112017024908A patent/BR112017024908A2/pt not_active Application Discontinuation
- 2016-05-23 PL PL16800590.8T patent/PL3297619T3/pl unknown
- 2016-05-23 IL IL296380A patent/IL296380A/en unknown
- 2016-05-23 PT PT168005908T patent/PT3297619T/pt unknown
- 2016-05-23 MX MX2017014456A patent/MX2017014456A/es unknown
- 2016-05-23 JP JP2017560663A patent/JP2018521007A/ja active Pending
- 2016-05-23 EP EP16800590.8A patent/EP3297619B1/en active Active
- 2016-05-23 SI SI201631606T patent/SI3297619T1/sl unknown
- 2016-05-23 US US15/576,319 patent/US20180140568A1/en not_active Abandoned
-
2017
- 2017-11-20 ZA ZA2017/07874A patent/ZA201707874B/en unknown
- 2017-11-20 IL IL255770A patent/IL255770B/en unknown
-
2018
- 2018-09-27 HK HK18112464.2A patent/HK1257800A1/zh unknown
-
2019
- 2019-05-06 US US16/403,974 patent/US20190321317A1/en not_active Abandoned
-
2021
- 2021-07-29 AU AU2021209279A patent/AU2021209279B2/en active Active
- 2021-08-25 IL IL285882A patent/IL285882A/en unknown
-
2022
- 2022-01-17 JP JP2022004811A patent/JP2022064908A/ja active Pending
- 2022-09-30 US US17/958,169 patent/US20240122887A1/en active Pending
-
2023
- 2023-12-13 AU AU2023282234A patent/AU2023282234A1/en not_active Abandoned
-
2024
- 2024-01-04 JP JP2024000227A patent/JP2024050575A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20190321317A1 (en) | 2019-10-24 |
AU2016268153A1 (en) | 2017-12-14 |
IL296380A (en) | 2022-11-01 |
WO2016191351A1 (en) | 2016-12-01 |
HK1257800A1 (zh) | 2019-11-01 |
ZA201707874B (en) | 2020-01-29 |
SI3297619T1 (sl) | 2023-02-28 |
JP2018521007A (ja) | 2018-08-02 |
CN107949379A (zh) | 2018-04-20 |
US20240122887A1 (en) | 2024-04-18 |
IL255770A (en) | 2018-01-31 |
PT3297619T (pt) | 2022-08-05 |
PL3297619T3 (pl) | 2023-02-13 |
CA3024783A1 (en) | 2016-12-01 |
EA201792571A1 (ru) | 2018-06-29 |
EP3297619A4 (en) | 2019-01-02 |
AU2023282234A1 (en) | 2024-01-18 |
IL255770B (en) | 2021-09-30 |
KR20180015158A (ko) | 2018-02-12 |
JP2022064908A (ja) | 2022-04-26 |
SG10202007661XA (en) | 2020-09-29 |
DK3297619T3 (da) | 2022-08-15 |
ES2925274T3 (es) | 2022-10-14 |
AU2021209279A1 (en) | 2021-08-19 |
EP3297619B1 (en) | 2022-07-06 |
IL285882A (en) | 2021-09-30 |
EP4108239A1 (en) | 2022-12-28 |
AU2016268153B2 (en) | 2021-08-12 |
AU2021209279B2 (en) | 2023-09-14 |
MX2017014456A (es) | 2018-03-16 |
JP2024050575A (ja) | 2024-04-10 |
US20180140568A1 (en) | 2018-05-24 |
EP3297619A1 (en) | 2018-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B154 | Notification of filing of divisional application [chapter 15.50 patent gazette] |
Free format text: O PEDIDO FOI DIVIDIDO NO BR122023018047-0 PROTOCOLO 870230078956 EM 05/09/2023 16:50. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |