SG10202007661XA - Therapeutic uses of l-4-chlorokynurenine - Google Patents

Therapeutic uses of l-4-chlorokynurenine

Info

Publication number
SG10202007661XA
SG10202007661XA SG10202007661XA SG10202007661XA SG10202007661XA SG 10202007661X A SG10202007661X A SG 10202007661XA SG 10202007661X A SG10202007661X A SG 10202007661XA SG 10202007661X A SG10202007661X A SG 10202007661XA SG 10202007661X A SG10202007661X A SG 10202007661XA
Authority
SG
Singapore
Prior art keywords
chlorokynurenine
therapeutic uses
therapeutic
Prior art date
Application number
SG10202007661XA
Inventor
H Ralph Snodgrass
E Cato Allen Iii
S Hicklin Jack
Original Assignee
Vistagen Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vistagen Therapeutics Inc filed Critical Vistagen Therapeutics Inc
Publication of SG10202007661XA publication Critical patent/SG10202007661XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
SG10202007661XA 2015-05-22 2016-05-23 Therapeutic uses of l-4-chlorokynurenine SG10202007661XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562179924P 2015-05-22 2015-05-22

Publications (1)

Publication Number Publication Date
SG10202007661XA true SG10202007661XA (en) 2020-09-29

Family

ID=57393671

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10202007661XA SG10202007661XA (en) 2015-05-22 2016-05-23 Therapeutic uses of l-4-chlorokynurenine

Country Status (20)

Country Link
US (3) US20180140568A1 (en)
EP (2) EP4108239A1 (en)
JP (3) JP2018521007A (en)
KR (1) KR20180015158A (en)
CN (1) CN107949379A (en)
AU (3) AU2016268153B2 (en)
BR (1) BR112017024908A2 (en)
CA (1) CA3024783A1 (en)
DK (1) DK3297619T3 (en)
EA (1) EA201792571A1 (en)
ES (1) ES2925274T3 (en)
HK (1) HK1257800A1 (en)
IL (3) IL296380A (en)
MX (1) MX2017014456A (en)
PL (1) PL3297619T3 (en)
PT (1) PT3297619T (en)
SG (1) SG10202007661XA (en)
SI (1) SI3297619T1 (en)
WO (1) WO2016191351A1 (en)
ZA (1) ZA201707874B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210149905A (en) 2013-01-22 2021-12-09 비스타젠 쎄라퓨틱스, 인크. Dosage forms and therapeutic uses of l-4-chlorokynurenine
AU2020271853A1 (en) * 2019-04-09 2021-11-25 Vistagen Therapeutics, Inc. Genetic variants associated with response to treatment of neurological disorders
US20230181541A1 (en) * 2020-06-24 2023-06-15 Biohaven Therapeutics Ltd. Compositions and methods for treating obsessive-compulsive disorder
WO2022221423A1 (en) * 2021-04-13 2022-10-20 Vistagen Therapeutics, Inc. Treatment of autoimmune anti-nmda-receptor encephalitis
CN115677519A (en) * 2021-07-22 2023-02-03 立科时代(武汉)生物科技有限公司 L-4-bromo-kynurenine and application thereof in preparation of drugs for treating depression
WO2024011105A1 (en) * 2022-07-05 2024-01-11 Mahana Therapeutics, Inc. Methods and systems for treating tinnitus using digital therapeutics

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484814A (en) 1991-02-28 1996-01-16 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
AU2981099A (en) * 1998-03-09 1999-09-27 Trustees Of Tufts College Treatment of compulsive behaviours in man and animals
TW518218B (en) * 1999-05-27 2003-01-21 Merck Patent Gmbh Pharmaceutical compositions comprising 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine or its physiologically acceptable salts for use in the treatment of sub-type anxiety disorders
AU2002229056A1 (en) * 2000-12-07 2002-06-18 Neuromolecular Inc. Methods for treating neuropsychiatric disorders with NMDA receptor antagonists
US20060063802A1 (en) * 2004-03-29 2006-03-23 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
MX2008013130A (en) * 2006-04-12 2008-11-19 Probiodrug Ag Enzyme inhibitors.
CA2606658A1 (en) * 2006-10-13 2008-04-13 Mike Tyers Compositions and methods for treating neurological disorders or damage
WO2009061935A2 (en) * 2007-11-06 2009-05-14 Emory University Methods of identifying safe nmda receptor antagonists
TW201026667A (en) * 2008-09-30 2010-07-16 Merz Pharma Gmbh & Co Kgaa Glycine b antagonists
CN104902883A (en) * 2012-08-23 2015-09-09 斯图亚特·L·韦格 Anxiolytic composition, formulation and method of use
KR20210149905A (en) * 2013-01-22 2021-12-09 비스타젠 쎄라퓨틱스, 인크. Dosage forms and therapeutic uses of l-4-chlorokynurenine
EP2970097B1 (en) 2013-03-14 2018-10-31 Vistagen Therapeutics, Inc. Methods for the synthesis of chiral kynurenine compounds
EP2970080A4 (en) 2013-03-14 2017-01-18 Vistagen Therapeutics, Inc. Synthesis of chiral kynurenine compounds and intermediates

Also Published As

Publication number Publication date
US20190321317A1 (en) 2019-10-24
AU2016268153A1 (en) 2017-12-14
IL296380A (en) 2022-11-01
WO2016191351A1 (en) 2016-12-01
HK1257800A1 (en) 2019-11-01
ZA201707874B (en) 2020-01-29
SI3297619T1 (en) 2023-02-28
JP2018521007A (en) 2018-08-02
CN107949379A (en) 2018-04-20
US20240122887A1 (en) 2024-04-18
BR112017024908A2 (en) 2018-07-31
IL255770A (en) 2018-01-31
PT3297619T (en) 2022-08-05
PL3297619T3 (en) 2023-02-13
CA3024783A1 (en) 2016-12-01
EA201792571A1 (en) 2018-06-29
EP3297619A4 (en) 2019-01-02
AU2023282234A1 (en) 2024-01-18
IL255770B (en) 2021-09-30
KR20180015158A (en) 2018-02-12
JP2022064908A (en) 2022-04-26
DK3297619T3 (en) 2022-08-15
ES2925274T3 (en) 2022-10-14
AU2021209279A1 (en) 2021-08-19
EP3297619B1 (en) 2022-07-06
IL285882A (en) 2021-09-30
EP4108239A1 (en) 2022-12-28
AU2016268153B2 (en) 2021-08-12
AU2021209279B2 (en) 2023-09-14
MX2017014456A (en) 2018-03-16
JP2024050575A (en) 2024-04-10
US20180140568A1 (en) 2018-05-24
EP3297619A1 (en) 2018-03-28

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