JP2018196379A5 - - Google Patents

Download PDF

Info

Publication number
JP2018196379A5
JP2018196379A5 JP2018121829A JP2018121829A JP2018196379A5 JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5 JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018121829 A JP2018121829 A JP 2018121829A JP 2018196379 A5 JP2018196379 A5 JP 2018196379A5
Authority
JP
Japan
Prior art keywords
mutation
primer
amplification
amplification reaction
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018121829A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018196379A (ja
Filing date
Publication date
Priority claimed from US13/840,142 external-priority patent/US10077474B2/en
Application filed filed Critical
Publication of JP2018196379A publication Critical patent/JP2018196379A/ja
Publication of JP2018196379A5 publication Critical patent/JP2018196379A5/ja
Pending legal-status Critical Current

Links

JP2018121829A 2012-05-29 2018-06-27 ヒトｂｒａｆのコドン６００における一塩基多型（ｓｎｐ）を検出する方法 Pending JP2018196379A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261652827P 2012-05-29 2012-05-29
US61/652,827 2012-05-29
US13/840,142 US10077474B2 (en) 2012-05-29 2013-03-15 Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
US13/840,142 2013-03-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015515106A Division JP6448534B2 (ja) 2012-05-29 2013-05-28 ヒトｂｒａｆのコドン６００における一塩基多型（ｓｎｐ）を検出する方法

Publications (2)

Publication Number Publication Date
JP2018196379A JP2018196379A (ja) 2018-12-13
JP2018196379A5 true JP2018196379A5 (enExample) 2019-02-14

Family

ID=49670689

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015515106A Expired - Fee Related JP6448534B2 (ja) 2012-05-29 2013-05-28 ヒトｂｒａｆのコドン６００における一塩基多型（ｓｎｐ）を検出する方法
JP2018121829A Pending JP2018196379A (ja) 2012-05-29 2018-06-27 ヒトｂｒａｆのコドン６００における一塩基多型（ｓｎｐ）を検出する方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2015515106A Expired - Fee Related JP6448534B2 (ja) 2012-05-29 2013-05-28 ヒトｂｒａｆのコドン６００における一塩基多型（ｓｎｐ）を検出する方法

Country Status (7)

Country Link
US (2) US10077474B2 (enExample)
EP (2) EP2855708B1 (enExample)
JP (2) JP6448534B2 (enExample)
AU (2) AU2013267660B2 (enExample)
CA (1) CA2875281A1 (enExample)
ES (1) ES2751371T3 (enExample)
WO (1) WO2013181125A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
BR112013020220B1 (pt) 2011-02-09 2020-03-17 Natera, Inc. Método para determinar o estado de ploidia de um cromossomo em um feto em gestação
WO2013159035A2 (en) 2012-04-19 2013-10-24 Medical College Of Wisconsin, Inc. Highly sensitive surveillance using detection of cell free dna
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
CN104928355A (zh) * 2014-03-19 2015-09-23 李跃 检测braf基因突变的方法及其试剂盒
US12492429B2 (en) 2014-04-21 2025-12-09 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
EP3134541B1 (en) 2014-04-21 2020-08-19 Natera, Inc. Detecting copy number variations (cnv) of chromosomal segments in cancer
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
US9868981B2 (en) 2015-06-11 2018-01-16 Bio-Rad Laboratories, Inc. Amplification assay with a probe competitor
EP3397766B1 (en) * 2015-12-31 2023-05-17 Quest Diagnostics Investments LLC Compositions and methods for screening mutations in thyroid cancer
RU2760913C2 (ru) 2016-04-15 2021-12-01 Натера, Инк. Способы выявления рака легкого
AU2017258799A1 (en) * 2016-04-29 2018-12-20 The Medical College Of Wisconsin, Inc. Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer
CN105861689A (zh) * 2016-05-06 2016-08-17 北京晋祺生物科技有限公司 一种cyp3a5*3的检测引物组合物、试剂盒及方法
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
CN111373050A (zh) 2017-06-20 2020-07-03 生物辐射实验室股份有限公司 用于遗传不稳定性的数字扩增试验
CA3067637A1 (en) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. Assessing transplant complication risk with total cell-free dna
WO2019099420A1 (en) * 2017-11-15 2019-05-23 Yan Wang A method for detecting multiple dna mutations and copy number variations
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
US12024738B2 (en) 2018-04-14 2024-07-02 Natera, Inc. Methods for cancer detection and monitoring
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
BR112021013020A2 (pt) * 2018-12-31 2021-09-14 Abbott Molecular Inc. Amplificação melhorada de ácidos nucleicos
KR102321902B1 (ko) * 2019-01-11 2021-11-05 주식회사 진캐스트 Braf 돌연변이 검출을 위한 dna 중합효소 및 이를 포함하는 키트
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
KR20220069111A (ko) * 2019-10-02 2022-05-26 러트거즈,더스테이트유니버시티오브뉴저지 희귀 서열 변이체를 검출하기 위한 검정 방법 및 키트
AU2021264510A1 (en) * 2020-04-28 2022-12-01 Cepheid Pseudo-complementary bases in genotyping and nucleic acid sequencing
JPWO2023013421A1 (enExample) * 2021-08-03 2023-02-09

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
CA1202962A (en) 1982-10-19 1986-04-08 David P. Clifford Substituted n-phenyl-n'-benzoyl ureas and their use as insecticides and acaricides
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US5310893A (en) 1986-03-31 1994-05-10 Hoffmann-La Roche Inc. Method for HLA DP typing
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5604099A (en) 1986-03-13 1997-02-18 Hoffmann-La Roche Inc. Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US4851331A (en) 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US5693517A (en) 1987-06-17 1997-12-02 Roche Molecular Systems, Inc. Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US5561058A (en) 1986-08-22 1996-10-01 Hoffmann-La Roche Inc. Methods for coupled high temperatures reverse transcription and polymerase chain reactions
US5310652A (en) 1986-08-22 1994-05-10 Hoffman-La Roche Inc. Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US5639611A (en) 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
US5137806A (en) 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
JP2985446B2 (ja) 1990-10-31 1999-11-29 東ソー株式会社 核酸の検出及び測定方法
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
EP0540997A1 (en) 1991-11-05 1993-05-12 F. Hoffmann-La Roche Ag Methods and reagents for HLA class I DNA typing
EP0655090B1 (en) 1992-04-27 2000-12-27 The Trustees Of Dartmouth College Detection of gene sequences in biological fluids
CA2126952C (en) 1994-06-28 2010-12-14 Sithian Pandian Probe, kit, and method of amplification for increasing the sensitivity of nucleic acid hybridization assays
US6235480B1 (en) 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
WO2003095645A1 (en) 2002-05-09 2003-11-20 New York University Assay for melanogenesis
US20030211483A1 (en) 2002-05-09 2003-11-13 Schroeder Benjamin G. Methods for the enrichment of low-abundance polynucleotides
WO2005027710A2 (en) 2002-09-11 2005-03-31 Sequenom, Inc. Methods for identifying subjects at risk of melanoma and treatments thereof
WO2004029288A2 (en) 2002-09-26 2004-04-08 Novartis Ag Pcr-based diagnostic method of detecting a mutation in the b-raf gene
JP4116856B2 (ja) 2002-10-02 2008-07-09 富士フイルム株式会社 １塩基多型の検出方法
US20040121374A1 (en) 2002-10-02 2004-06-24 Yoshihide Iwaki Method for detecting single nucleotide polymorphisms
US7250289B2 (en) 2002-11-20 2007-07-31 Affymetrix, Inc. Methods of genetic analysis of mouse
US7378233B2 (en) 2003-04-12 2008-05-27 The Johns Hopkins University BRAF mutation T1796A in thyroid cancers
JP5162133B2 (ja) 2003-12-03 2013-03-13 アボット・ラボラトリーズ 二本鎖直鎖核酸プローブ及びその使用
EP1541695A1 (en) 2003-12-09 2005-06-15 Nanogen Recognomics GmbH Use of a mutation in the BRAF gene for the determination of the malignancy of melanoma cells
WO2005066346A1 (ja) 2003-12-26 2005-07-21 Takeshi Nagasaka 核酸増幅用プライマー、核酸増幅用プライマーセット及びこれを用いた癌の検査方法
ES2244308B1 (es) 2004-01-21 2007-02-16 Oryzon Genomics, S.A. Metodo de diagnostico molecular y tratamiento en cancer colorrectal esporadico inestable.
US7442507B2 (en) 2005-01-24 2008-10-28 New York University School Of Medicine Methods for detecting circulating mutant BRAF DNA
US20070020657A1 (en) 2005-05-20 2007-01-25 Grebe Stefan K Methods for detecting circulating tumor cells
WO2007002433A1 (en) * 2005-06-22 2007-01-04 Plexxikon, Inc. Pyrrolo [2, 3-b] pyridine derivatives as protein kinase inhibitors
US10144970B2 (en) 2005-07-13 2018-12-04 University Of Utah Research Foundation Methods and compositions related to a BRAF mutation and microsatellite stability
WO2007106534A2 (en) 2006-03-14 2007-09-20 Harbor-Ucla Research And Education Institute Selective amplification of minority mutations using primer blocking high-affinity oligonucleotides
US7803543B2 (en) * 2007-01-19 2010-09-28 Chang Gung University Methods and kits for the detection of nucleotide mutations using peptide nucleic acid as both PCR clamp and sensor probe
US9556491B2 (en) 2007-02-26 2017-01-31 John Wayne Cancer Institute Utility of B-RAF DNA mutation in diagnosis and treatment of cancer
US20100173294A1 (en) 2007-09-11 2010-07-08 Roche Molecular Systems, Inc. Diagnostic test for susceptibility to b-raf kinase inhibitors
US20110212991A1 (en) 2007-09-11 2011-09-01 Roche Molecular Systems, Inc. Diagnostic Test for Susceptibility to B-RAF Kinase Inhibitors
EP2220503A1 (en) 2007-11-30 2010-08-25 Schering Corporation Braf biomarkers
WO2010011884A2 (en) 2008-07-25 2010-01-28 University Of Florida Research Foundation, Inc. Novel nucleic acid-based molecular probes
EP3216874A1 (en) 2008-09-05 2017-09-13 TOMA Biosciences, Inc. Methods for stratifying and annotating cancer drug treatment options
CN101487051B (zh) 2009-02-24 2011-07-20 广州益善生物技术有限公司 Braf基因突变的检测探针、液相芯片及其检测方法
CA2770716A1 (en) 2009-08-11 2011-02-17 Response Genetics, Inc. Methods, primers, probes and kits useful for the detection of braf mutations
US8728763B2 (en) * 2009-08-11 2014-05-20 Response Genetics Methods, primers, probes and kits useful for the detection of BRAF mutations
KR101825117B1 (ko) 2010-02-01 2018-02-06 주식회사 파나진 Ｐｎａ 기반의 실시간 ｐｃｒ 클램핑을 이용한 ｂｒａｆ 돌연변이 검출 방법 및 키트
CN102161990A (zh) 2010-02-24 2011-08-24 北京雅康博生物科技有限公司 用于定量检测braf突变的试剂盒
WO2011106298A1 (en) 2010-02-25 2011-09-01 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
WO2011104694A2 (en) 2010-02-26 2011-09-01 GAMMAGENETICS Sàrl Detection of braf v600e mutation by allele specific real time quantitative pcr (as-qpcr) using locked nucleic acids primers and beacon probes
WO2011119934A2 (en) 2010-03-26 2011-09-29 Mayo Foundation For Medical Education And Research Methods and materials for detecting colorectal neoplasm
CN102234684B (zh) 2010-04-23 2014-01-01 益善生物技术股份有限公司 Braf基因突变检测特异性引物和液相芯片
EP2426217A1 (en) 2010-09-03 2012-03-07 Centre National de la Recherche Scientifique (CNRS) Analytical methods for cell free nucleic acids and applications

Similar Documents

Publication Publication Date Title
JP2018196379A5 (enExample)
CN106661627B (zh) 使用重叠非等位基因特异性引物和等位基因特异性阻断剂寡核苷酸的组合物进行等位基因特异性扩增
JP2005270108A5 (enExample)
JP2021510541A5 (enExample)
CN111699269A (zh) 新引物及其用途
JP2015156872A5 (enExample)
JP2017519774A5 (enExample)
JP2017510244A5 (enExample)
JP2016500257A5 (enExample)
JP2017537658A5 (enExample)
JP2014083053A5 (enExample)
JP7343264B2 (ja) Ｄｎａライブラリーの作製方法及びｄｎａライブラリーを用いたゲノムｄｎａ解析方法
JP2012513216A5 (enExample)
CN105378111A (zh) 进行聚合酶链式反应的方法及其相关应用
JP2010035532A (ja) アレル特異的ｐｃｒ法
JP2016527904A5 (enExample)
JP2017532030A5 (enExample)
JP2008504825A5 (enExample)
KR101856205B1 (ko) 핵산의 대립형질 특이적 프라이머 및 이를 이용한 유전형 판별 방법
EP3546594A2 (en) Multi-copy reference assay
JP2005323565A (ja) 標的ｄｎａ配列において一塩基変異多型の存在を検出する方法及びキット
US20230407383A1 (en) Gene specific spatial rolling circle amplification and ngs sequencing
CN104152542B (zh) 肿瘤abl1基因位点分型检测试剂盒、使用方法及应用
JP2015019631A5 (enExample)
JP2008507955A5 (enExample)