JP2018102926A - 生体植立用インプラント及びその製造方法 - Google Patents
生体植立用インプラント及びその製造方法 Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
【解決手段】発毛機能性のサイトカイン分泌能を有する幹細胞を含む、生体植立用インプラント。前記幹細胞は、低酸素条件下で培養された幹細胞、特に、羊水由来幹細胞(好ましくは逆分化羊水幹細胞)又は胎児由来間葉系幹細胞であることが好ましい。前記発毛機能性のサイトカインは、bFGF、PDGF−AA、IGF及びWnt7aで構成される群から選択される。
【選択図】図12
Description
Claims (13)
- 発毛機能性のサイトカイン分泌能を有する幹細胞を含む、生体植立用インプラント。
- 脱毛の治療または改善のための、請求項1に記載の生体植立用インプラント。
- 発毛促進のための、請求項1に記載の生体植立用インプラント。
- 前記発毛機能性のサイトカインはbFGF、PDGF−AA、IGF及びWnt7aで構成される群から選択されることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記幹細胞は、低酸素条件下で培養された幹細胞であることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記幹細胞は、羊水由来幹細胞であることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記幹細胞は、逆分化羊水幹細胞であることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記幹細胞は、胎児由来間葉系幹細胞であることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記生体植立用インプラントは、前記幹細胞を1.0×103ないし1.0×1010個含むことを特徴とする、請求項1に記載の生体植立用インプラント。
- 頭皮下に植立されることを特徴とする、請求項1に記載の生体植立用インプラント。
- 前記生体植立用インプラントは、老化による脱毛の治療または改善のためのものである、請求項1に記載の生体植立用インプラント。
- 発毛機能性のサイトカイン分泌能を有する幹細胞を生体植立用インプラント内に注入する段階を含む、
脱毛改善のための生体植立用インプラントの製造方法。 - 発毛機能性のサイトカイン分泌能を有する幹細胞を生体植立用インプラント内に注入する段階を含む、
脱毛治療のための生体植立用インプラントの製造方法。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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KR10-2016-0178521 | 2016-12-23 | ||
KR20160178521 | 2016-12-23 | ||
KR10-2017-0106012 | 2017-08-22 | ||
KR1020170106012A KR102009081B1 (ko) | 2016-12-23 | 2017-08-22 | 발모 촉진을 위한 생체 식립용 임플란트 |
Publications (2)
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JP2018102926A true JP2018102926A (ja) | 2018-07-05 |
JP6557717B2 JP6557717B2 (ja) | 2019-08-07 |
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JP2017246459A Active JP6557717B2 (ja) | 2016-12-23 | 2017-12-22 | 生体植立用インプラント及びその製造方法 |
Country Status (3)
Country | Link |
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US (1) | US10993904B2 (ja) |
JP (1) | JP6557717B2 (ja) |
CN (1) | CN108236614B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020505058A (ja) * | 2017-01-11 | 2020-02-20 | ステムラボ・インコーポレイテッド | ナノグを導入した羊水内胎児由来間葉系幹細胞から獲得したエクソソーム内に含まれた育毛促進用組成物の製造方法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006294581B2 (en) | 2005-09-27 | 2011-11-03 | Tissuetech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
ES2846789T3 (es) | 2012-07-11 | 2021-07-29 | Tissuetech Inc | Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos |
WO2016138025A2 (en) | 2015-02-23 | 2016-09-01 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
CN107847526A (zh) | 2015-05-20 | 2018-03-27 | 组织技术公司 | 用于预防上皮细胞的增殖和上皮‑间充质转换的组合物和方法 |
TW201733600A (zh) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | 胎兒扶持組織物及使用方法 |
CN112675153A (zh) * | 2019-10-17 | 2021-04-20 | 上海萨美细胞技术有限公司 | 无细胞脂肪组织提取物促进毛发生长、固发的用途 |
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