|
DE3321826A1
(de)
|
1983-06-15 |
1984-12-20 |
Schering AG, 1000 Berlin und 4709 Bergkamen |
13(alpha)-alkylgonane, deren herstellung und diese enthaltende pharmazeutische praeparate
|
|
ES8502612A1
(es)
|
1983-06-15 |
1985-02-01 |
Schering Ag |
Procedimiento para la preparacion de 13a-alquilgonanos
|
|
US4780461A
(en)
|
1983-06-15 |
1988-10-25 |
Schering Aktiengesellschaft |
13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same
|
|
US4742000A
(en)
|
1986-05-02 |
1988-05-03 |
University Of Chicago |
Antibody to human progesterone receptor and diagnostic materials and methods
|
|
DE3630030A1
(de)
|
1986-09-01 |
1988-03-03 |
Schering Ag |
13(alpha)-alkylgonan-(delta)(pfeil hoch)9(pfeil hoch)(pfeil hoch)((pfeil hoch)(pfeil hoch)1(pfeil hoch)1(pfeil hoch))(pfeil hoch)-5,10-epoxide
|
|
US4774236A
(en)
|
1986-09-17 |
1988-09-27 |
Research Triangle Institute |
17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them
|
|
IE60780B1
(en)
|
1987-01-23 |
1994-08-10 |
Akzo Nv |
New 11-aryl steroid derivatives
|
|
DE3822770A1
(de)
|
1988-07-01 |
1990-01-04 |
Schering Ag |
13-alkyl-11ss-phenylgonane
|
|
US5283190A
(en)
|
1989-07-31 |
1994-02-01 |
Traish Adbulmaged M |
Specific monoclonal antibodies against a defined epitope of progesterone receptor and methods for their use
|
|
DE4008584A1
(de)
|
1990-03-15 |
1991-09-26 |
Schering Ag |
Verfahren zur herstellung von zwischenprodukten fuer die antigestagensynthese (onapristonsynthese)
|
|
US5141961A
(en)
|
1991-06-27 |
1992-08-25 |
Richrdson-Vicks Inc. |
Process for solubilizing difficulty soluble pharmaceutical actives
|
|
MX9301121A
(es)
|
1992-03-02 |
1993-09-01 |
Schering Ag |
Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina.
|
|
CN1053450C
(zh)
|
1992-11-19 |
2000-06-14 |
北京第三制药厂 |
17位取代11β－取代芳香基－4,9－雌甾二烯类化合物的全合成法
|
|
DE4332283A1
(de)
|
1993-09-20 |
1995-04-13 |
Jenapharm Gmbh |
Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
|
|
EP0787002B1
(de)
*
|
1994-10-24 |
2006-12-13 |
Schering Aktiengesellschaft |
Kompetitive progesteronantagonisten zur bedarfsorientierten weiblichen fertilitätskontrolle
|
|
US5759577A
(en)
|
1995-01-17 |
1998-06-02 |
American Home Products Corporation |
Controlled release of steroids from sugar coatings
|
|
US6900193B1
(en)
|
1996-05-01 |
2005-05-31 |
The United States Of America As Represented By The Department Of Health And Human Services |
Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
|
|
IL122740A
(en)
|
1997-01-15 |
2003-09-17 |
Akzo Nobel Nv |
16-hydroxy-11-(substituted phenyl)-estra-9,4-diene derivatives, their preparation and pharmaceutical compositions containing them
|
|
US5962444A
(en)
|
1998-05-29 |
1999-10-05 |
Research Triangle Institute |
17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
|
|
US6537584B1
(en)
|
1999-11-12 |
2003-03-25 |
Macromed, Inc. |
Polymer blends that swell in an acidic environment and deswell in a basic environment
|
|
PT1282443E
(pt)
|
2000-05-19 |
2009-12-04 |
Genentech Inc |
Análise de detecção génica para melhorar a probabilidade de uma resposta eficaz a uma terapia do cancro com um antagonista de erbb
|
|
US6750015B2
(en)
|
2000-06-28 |
2004-06-15 |
Kathryn B. Horwitz |
Progesterone receptor-regulated gene expression and methods related thereto
|
|
UY26966A1
(es)
|
2000-10-18 |
2002-06-20 |
Schering Ag |
Uso de antiprogestinas para la inducción de apoptosis en una célula
|
|
US7381976B2
(en)
|
2001-03-13 |
2008-06-03 |
Triton Thalassic Technologies, Inc. |
Monochromatic fluid treatment systems
|
|
AUPR546801A0
(en)
|
2001-06-05 |
2001-06-28 |
Commonwealth Scientific And Industrial Research Organisation |
Recombinant antibodies
|
|
US7105642B2
(en)
|
2001-08-03 |
2006-09-12 |
Cell Signalling Technology, Inc. |
Monoclonal antibodies specific for phosphorylated estrogen receptor alpha (Ser118) and uses thereof
|
|
US20040121304A1
(en)
|
2001-12-21 |
2004-06-24 |
Ulrike Fuhrmann |
Method for screening for progesterone receptor isoform-specific ligands and for tissue-selective progesterone receptor ligands
|
|
AU2004217988C1
(en)
|
2003-02-28 |
2010-06-03 |
Southwest Foundation For Biomedical Research |
Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
|
|
US20040265371A1
(en)
|
2003-06-25 |
2004-12-30 |
Looney Dwayne Lee |
Hemostatic devices and methods of making same
|
|
US7247625B2
(en)
*
|
2003-10-09 |
2007-07-24 |
Wyeth |
6-amino-1,4-dihydro-benzo[d][1,3] oxazin-2-ones and analogs useful as progesterone receptor modulators
|
|
DE602005026290D1
(de)
|
2004-07-09 |
2011-03-24 |
Population Council Inc |
Zusammensetzungen mit verzögerter freisetzung mit progesteron-rezeptormodulatoren
|
|
BRPI0515562A
(pt)
|
2004-09-22 |
2008-07-29 |
Tripath Imaging Inc |
métodos e composições para avaliação do prognóstico do cáncer de mama
|
|
CA2604218A1
(en)
|
2005-04-20 |
2006-10-26 |
Pfizer Limited |
Pyrazole derivatives as progesterone receptor antagonists
|
|
WO2007078599A2
(en)
|
2005-12-16 |
2007-07-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Functional arrays for high throughput characterization of gene expression regulatory elements
|
|
US20070167971A1
(en)
|
2006-01-17 |
2007-07-19 |
Raymond Huey |
Devices and methods for promoting the formation of blood clots in esophageal varices
|
|
US20070166372A1
(en)
|
2006-01-19 |
2007-07-19 |
Mai De Ltd. |
Preparation of solid coprecipitates of amorphous valsartan
|
|
AU2007217094A1
(en)
|
2006-02-17 |
2007-08-30 |
Janssen Pharmaceutica N.V. |
11-phosphorous steroid derivatives useful as progesterone receptor modulators
|
|
DE102006054535A1
(de)
|
2006-11-15 |
2008-05-21 |
Bayer Schering Pharma Aktiengesellschaft |
Progesteronrezeptorantagonisten
|
|
WO2008128783A2
(en)
|
2007-04-24 |
2008-10-30 |
Dsm Ip Assets B.V. |
Photochemical process for the preparation of a previtamin d
|
|
CA2596204C
(en)
|
2007-08-07 |
2019-02-26 |
Historx, Inc. |
Method and system for determining an optimal dilution of a reagent
|
|
WO2009025759A1
(en)
|
2007-08-17 |
2009-02-26 |
Progenics Pharmaceuticals (Nevada), Inc. |
Tight junction proteins associated with infection and entry of hepatitis c virus (hcv), methods and uses thereof
|
|
TW200927142A
(en)
*
|
2007-10-12 |
2009-07-01 |
Novartis Ag |
Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
|
|
EP2075246A1
(en)
|
2007-12-27 |
2009-07-01 |
M. J. Institute of Research |
A process for preparation of amorphous form of atorvastatin hemi-calcium salt
|
|
CN101939009B
(zh)
|
2008-02-05 |
2013-07-17 |
哈博生物科学公司 |
药学固体形式
|
|
TW201002736A
(en)
|
2008-04-28 |
2010-01-16 |
Repros Therapeutics Inc |
Compositions and methods for treating progesterone-dependent conditions
|
|
TWI539953B
(zh)
|
2008-04-28 |
2016-07-01 |
瑞波若斯治療學公司 |
用於治療乳癌之組成物和方法
|
|
EP2412662A4
(en)
|
2009-03-27 |
2017-03-29 |
Komatsu Ltd. |
Fuel saving control device for working machine and fuel saving control method for working machine
|
|
WO2010126590A1
(en)
|
2009-04-27 |
2010-11-04 |
Cold Spring Harbor Laboratory |
Ptp1b inhibitors
|
|
WO2010141485A1
(en)
|
2009-06-01 |
2010-12-09 |
Samuel Waxman Cancer Research Foundation |
Compositions and methods to induce differentiation and growth inhibition in breast cancer
|
|
MX2012000680A
(es)
|
2009-07-15 |
2012-02-28 |
S Bio Pte Ltd |
Sal de citrato de 9e-15-(2-pirrolidin-1-il-etoxi)-7,12,25-trioxa-1 9,21,24-triaza-tetraciclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2 ,4,9,14,16,18(26),20,22-nonaeno.
|
|
US20110293511A1
(en)
|
2009-09-29 |
2011-12-01 |
Terrance Grant Johns |
Specific binding proteins and uses thereof
|
|
US8261855B2
(en)
*
|
2009-11-11 |
2012-09-11 |
Flanders Electric, Ltd. |
Methods and systems for drilling boreholes
|
|
WO2011084513A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
|
JP5894143B2
(ja)
|
2010-03-22 |
2016-03-23 |
リプロス セラピューティクス インコーポレイテッド |
抗黄体ホルモンの無毒送達のための組成物および方法
|
|
AU2011325956B2
(en)
|
2010-11-12 |
2016-07-14 |
The General Hospital Corporation |
Polycomb-associated non-coding RNAs
|
|
US20140018404A1
(en)
|
2010-12-16 |
2014-01-16 |
Celgene Corporation |
Controlled release oral dosage forms of poorly soluble drugs and uses thereof
|
|
CA2822462A1
(en)
|
2010-12-20 |
2012-06-28 |
The General Hospital Corporation |
Polycomb-associated non-coding rnas
|
|
WO2012122514A1
(en)
|
2011-03-09 |
2012-09-13 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
|
PT2683384E
(pt)
*
|
2011-03-11 |
2016-03-11 |
Celgene Corp |
Métodos de tratamento de cancro utilizando 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidina-2,6-diona
|
|
US9618512B2
(en)
|
2011-04-15 |
2017-04-11 |
J-Pharma Co., Ltd. |
Biomarker for breast cancer
|
|
HUE028603T2
(en)
|
2011-05-13 |
2016-12-28 |
Ganymed Pharmaceuticals Ag |
Antibodies for treatment of cancer expressing claudin 6
|
|
US20130029953A1
(en)
*
|
2011-07-28 |
2013-01-31 |
Klaus Nickisch |
Progesterone antagonists
|
|
WO2013052652A1
(en)
|
2011-10-04 |
2013-04-11 |
Erard Gilles |
Methods and systems for identifying and treating anti-progestin sensitive tumors
|
|
BR112014013709A2
(pt)
|
2011-12-08 |
2017-08-22 |
Fund Sales |
Métodos, composições farmaceuticas, e kits, para tratar cânceres resitentes às antiprogestinas
|
|
US20130338016A1
(en)
|
2012-04-17 |
2013-12-19 |
Vala Sciences, Inc. |
Method For Integrated Pathology Diagnosis And Digital Biomarker Pattern Analysis
|
|
RU2014147625A
(ru)
|
2012-04-27 |
2016-06-20 |
Реджентс Оф Зэ Юниверсити Оф Миннесота |
Прогнозирование рака молочной железы, предсказание подтипа прогестероновых рецепторов и предсказание ответа на лечение антипрогестином на основании генной экспрессии
|
|
AU2013295815A1
(en)
|
2012-07-24 |
2015-02-05 |
Cedars-Sinai Medical Center |
A novel method to detect resistance to chemotherapy in patients with lung cancer
|
|
AU2013358968B2
(en)
|
2012-12-13 |
2017-12-21 |
Warsaw Orthopedic, Inc. |
Compositions and methods comprising polyethylene glycol and magnesium for treatment of neuronal injury
|
|
KR20150130359A
(ko)
|
2013-03-12 |
2015-11-23 |
아르노 테라퓨틱스 |
오나프리스톤 다형태 및 사용 방법
|
|
US20140363425A1
(en)
|
2013-03-13 |
2014-12-11 |
J. Dinny Graham |
Systems and methods for identifying cancers having activated progesterone receptors
|
|
US9096641B2
(en)
|
2013-06-05 |
2015-08-04 |
Evestra, Inc. |
Imidazolyl progesterone antagonists
|
|
CN103483449A
(zh)
|
2013-08-20 |
2014-01-01 |
东北农业大学 |
两种scFv抗体、其编码基因及其在制备治疗或预防鸡传染性法氏囊病制剂中的应用
|
|
CA2939241A1
(en)
|
2014-04-08 |
2015-10-15 |
Arno Therapeutics, Inc. |
Systems and methods for identifying progesterone receptor subtypes
|
|
CN113559075A
(zh)
|
2014-11-17 |
2021-10-29 |
康泰科思特生物制药公司 |
奥那司酮延长释放组合物和方法
|
|
EP3273983B1
(en)
|
2015-03-23 |
2021-05-05 |
Evestra, Inc. |
Novel cytotoxic agents that preferentially target leukemia inhibitory factor (lif) for the treatment of malignancies and as new contraceptive agents
|
|
CA2998924A1
(en)
|
2015-09-25 |
2017-03-30 |
Context Biopharma Inc. |
Methods of making onapristone intermediates
|
|
JP2019503353A
(ja)
|
2015-12-15 |
2019-02-07 |
コンテキスト・バイオファーマ・インコーポレイテッド |
非晶質オナプリストン組成物およびそれを作製する方法
|
|
JP2019513706A
(ja)
|
2016-03-21 |
2019-05-30 |
コンテキスト・バイオファーマ・インコーポレイテッド |
オナプリストン代謝物質組成物及び方法
|
|
JP7082065B2
(ja)
|
2016-05-02 |
2022-06-07 |
テトラジェネティクス， インコーポレイテッド |
抗Ｋｖ１．３抗体ならびにその産生方法および使用方法
|
|
WO2018067198A1
(en)
|
2016-10-03 |
2018-04-12 |
The Regents Of The University Of California |
Inhibitory antibodies and methods of use thereof
|