AU2015350241B2 - Onapristone extended-release compositions and methods - Google Patents

Onapristone extended-release compositions and methods Download PDF

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Publication number
AU2015350241B2
AU2015350241B2 AU2015350241A AU2015350241A AU2015350241B2 AU 2015350241 B2 AU2015350241 B2 AU 2015350241B2 AU 2015350241 A AU2015350241 A AU 2015350241A AU 2015350241 A AU2015350241 A AU 2015350241A AU 2015350241 B2 AU2015350241 B2 AU 2015350241B2
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AU
Australia
Prior art keywords
onapristone
extended
release
pharmaceutical composition
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2015350241A
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English (en)
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AU2015350241A1 (en
Inventor
Stefan PRONIUK
Alexander ZUKIWSKI
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Context Biopharma Inc
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Context Biopharma Inc
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Publication of AU2015350241A1 publication Critical patent/AU2015350241A1/en
Assigned to CONTEXT BIOPHARMA INC. reassignment CONTEXT BIOPHARMA INC. Request for Assignment Assignors: ARNO THERAPEUTICS, INC.
Application granted granted Critical
Publication of AU2015350241B2 publication Critical patent/AU2015350241B2/en
Priority to AU2021218093A priority Critical patent/AU2021218093A1/en
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Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2015350241A 2014-11-17 2015-11-16 Onapristone extended-release compositions and methods Ceased AU2015350241B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2021218093A AU2021218093A1 (en) 2014-11-17 2021-08-18 Onapristone Extended-Release Compositions And Methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462080868P 2014-11-17 2014-11-17
US62/080,868 2014-11-17
PCT/US2015/060940 WO2016081383A1 (en) 2014-11-17 2015-11-16 Onapristone extended-release compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021218093A Division AU2021218093A1 (en) 2014-11-17 2021-08-18 Onapristone Extended-Release Compositions And Methods

Publications (2)

Publication Number Publication Date
AU2015350241A1 AU2015350241A1 (en) 2017-05-04
AU2015350241B2 true AU2015350241B2 (en) 2021-05-20

Family

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Family Applications (2)

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AU2015350241A Ceased AU2015350241B2 (en) 2014-11-17 2015-11-16 Onapristone extended-release compositions and methods
AU2021218093A Abandoned AU2021218093A1 (en) 2014-11-17 2021-08-18 Onapristone Extended-Release Compositions And Methods

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2021218093A Abandoned AU2021218093A1 (en) 2014-11-17 2021-08-18 Onapristone Extended-Release Compositions And Methods

Country Status (11)

Country Link
US (3) US10786461B2 (enExample)
EP (1) EP3247362A4 (enExample)
JP (1) JP6655075B2 (enExample)
KR (1) KR20170084086A (enExample)
CN (2) CN113559075A (enExample)
AU (2) AU2015350241B2 (enExample)
CA (1) CA2966753A1 (enExample)
HK (1) HK1246653A1 (enExample)
MX (1) MX391191B (enExample)
RU (1) RU2017112748A (enExample)
WO (1) WO2016081383A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017112748A (ru) 2014-11-17 2018-12-19 Арно Терапьютикс, Инк. Композиции онапристона пролонгированного действия и способы
AU2016326657B2 (en) 2015-09-25 2019-10-24 Context Biopharma, Inc. Methods of making onapristone intermediates
HK1255104A1 (zh) 2015-12-15 2019-08-02 Context Biopharma Inc. 无定形的奥那司酮组合物及其制备方法
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

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US20130029953A1 (en) * 2011-07-28 2013-01-31 Klaus Nickisch Progesterone antagonists
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US6143754A (en) * 1994-10-24 2000-11-07 Schering Aktiengesellschaft Competitive progesterone antagonist for demand-oriented female birth control
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Also Published As

Publication number Publication date
JP6655075B2 (ja) 2020-02-26
US20210220279A1 (en) 2021-07-22
WO2016081383A1 (en) 2016-05-26
EP3247362A1 (en) 2017-11-29
US10786461B2 (en) 2020-09-29
EP3247362A4 (en) 2018-10-10
US20230157960A1 (en) 2023-05-25
MX2017005163A (es) 2018-01-18
AU2015350241A1 (en) 2017-05-04
KR20170084086A (ko) 2017-07-19
MX391191B (es) 2025-03-21
JP2017537883A (ja) 2017-12-21
HK1246653A1 (zh) 2018-09-14
CN106999501B (zh) 2021-08-13
AU2021218093A1 (en) 2021-09-09
CN106999501A (zh) 2017-08-01
US11672762B2 (en) 2023-06-13
RU2017112748A (ru) 2018-12-19
RU2017112748A3 (enExample) 2019-06-26
US20160166583A1 (en) 2016-06-16
CA2966753A1 (en) 2016-05-26
CN113559075A (zh) 2021-10-29

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Owner name: CONTEXT BIOPHARMA INC.

Free format text: FORMER APPLICANT(S): ARNO THERAPEUTICS, INC.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired