RU2017112748A - Композиции онапристона пролонгированного действия и способы - Google Patents

Композиции онапристона пролонгированного действия и способы Download PDF

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Publication number
RU2017112748A
RU2017112748A RU2017112748A RU2017112748A RU2017112748A RU 2017112748 A RU2017112748 A RU 2017112748A RU 2017112748 A RU2017112748 A RU 2017112748A RU 2017112748 A RU2017112748 A RU 2017112748A RU 2017112748 A RU2017112748 A RU 2017112748A
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RU
Russia
Prior art keywords
pharmaceutical composition
onapristone
sustained
release pharmaceutical
day
Prior art date
Application number
RU2017112748A
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English (en)
Russian (ru)
Other versions
RU2017112748A3 (enExample
Inventor
Александер ЖУКИВСКИ
Стефан ПРОНЮК
Original Assignee
Арно Терапьютикс, Инк.
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Application filed by Арно Терапьютикс, Инк. filed Critical Арно Терапьютикс, Инк.
Publication of RU2017112748A publication Critical patent/RU2017112748A/ru
Publication of RU2017112748A3 publication Critical patent/RU2017112748A3/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2017112748A 2014-11-17 2015-11-16 Композиции онапристона пролонгированного действия и способы RU2017112748A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462080868P 2014-11-17 2014-11-17
US62/080,868 2014-11-17
PCT/US2015/060940 WO2016081383A1 (en) 2014-11-17 2015-11-16 Onapristone extended-release compositions and methods

Publications (2)

Publication Number Publication Date
RU2017112748A true RU2017112748A (ru) 2018-12-19
RU2017112748A3 RU2017112748A3 (enExample) 2019-06-26

Family

ID=56014429

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017112748A RU2017112748A (ru) 2014-11-17 2015-11-16 Композиции онапристона пролонгированного действия и способы

Country Status (11)

Country Link
US (3) US10786461B2 (enExample)
EP (1) EP3247362A4 (enExample)
JP (1) JP6655075B2 (enExample)
KR (1) KR20170084086A (enExample)
CN (2) CN113559075A (enExample)
AU (2) AU2015350241B2 (enExample)
CA (1) CA2966753A1 (enExample)
HK (1) HK1246653A1 (enExample)
MX (1) MX391191B (enExample)
RU (1) RU2017112748A (enExample)
WO (1) WO2016081383A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017112748A (ru) 2014-11-17 2018-12-19 Арно Терапьютикс, Инк. Композиции онапристона пролонгированного действия и способы
AU2016326657B2 (en) 2015-09-25 2019-10-24 Context Biopharma, Inc. Methods of making onapristone intermediates
HK1255104A1 (zh) 2015-12-15 2019-08-02 Context Biopharma Inc. 无定形的奥那司酮组合物及其制备方法
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

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Also Published As

Publication number Publication date
JP6655075B2 (ja) 2020-02-26
US20210220279A1 (en) 2021-07-22
WO2016081383A1 (en) 2016-05-26
EP3247362A1 (en) 2017-11-29
US10786461B2 (en) 2020-09-29
EP3247362A4 (en) 2018-10-10
US20230157960A1 (en) 2023-05-25
MX2017005163A (es) 2018-01-18
AU2015350241A1 (en) 2017-05-04
KR20170084086A (ko) 2017-07-19
MX391191B (es) 2025-03-21
JP2017537883A (ja) 2017-12-21
HK1246653A1 (zh) 2018-09-14
CN106999501B (zh) 2021-08-13
AU2021218093A1 (en) 2021-09-09
CN106999501A (zh) 2017-08-01
US11672762B2 (en) 2023-06-13
RU2017112748A3 (enExample) 2019-06-26
US20160166583A1 (en) 2016-06-16
AU2015350241B2 (en) 2021-05-20
CA2966753A1 (en) 2016-05-26
CN113559075A (zh) 2021-10-29

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Effective date: 20191022