ATE497745T1 - Zusammensetzungen mit verzögerter freisetzung mit progesteron-rezeptormodulatoren - Google Patents
Zusammensetzungen mit verzögerter freisetzung mit progesteron-rezeptormodulatorenInfo
- Publication number
- ATE497745T1 ATE497745T1 AT05771439T AT05771439T ATE497745T1 AT E497745 T1 ATE497745 T1 AT E497745T1 AT 05771439 T AT05771439 T AT 05771439T AT 05771439 T AT05771439 T AT 05771439T AT E497745 T1 ATE497745 T1 AT E497745T1
- Authority
- AT
- Austria
- Prior art keywords
- sustained release
- progesterone receptor
- release compositions
- compositions containing
- receptor modulators
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58678304P | 2004-07-09 | 2004-07-09 | |
PCT/US2005/024474 WO2006010097A2 (en) | 2004-07-09 | 2005-07-08 | Sustained release compositions containing progesterone receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE497745T1 true ATE497745T1 (de) | 2011-02-15 |
Family
ID=35785781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05771439T ATE497745T1 (de) | 2004-07-09 | 2005-07-08 | Zusammensetzungen mit verzögerter freisetzung mit progesteron-rezeptormodulatoren |
Country Status (16)
Country | Link |
---|---|
US (1) | US8865200B2 (de) |
EP (1) | EP1768625B1 (de) |
JP (2) | JP5017109B2 (de) |
KR (1) | KR101229701B1 (de) |
CN (1) | CN101080205B (de) |
AT (1) | ATE497745T1 (de) |
AU (1) | AU2005265357B2 (de) |
BR (1) | BRPI0513141A (de) |
CA (1) | CA2573266C (de) |
DE (1) | DE602005026290D1 (de) |
DK (1) | DK1768625T3 (de) |
ES (1) | ES2360806T3 (de) |
MX (1) | MX2007000273A (de) |
NZ (1) | NZ552720A (de) |
PT (1) | PT1768625E (de) |
WO (1) | WO2006010097A2 (de) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436428B1 (en) * | 2000-03-21 | 2002-08-20 | Enhance Pharmaceuticals, Inc. | Device and method for treating urinary incontinence in females |
GB0222522D0 (en) * | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
US8404272B2 (en) | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
US8399013B2 (en) | 2003-06-26 | 2013-03-19 | Poly-Med, Inc. | Partially absorbable fiber-reinforced composites for controlled drug delivery |
GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
US8062658B2 (en) * | 2004-12-14 | 2011-11-22 | Poly-Med, Inc. | Multicomponent bioactive intravaginal ring |
EP1862468A1 (de) | 2006-06-02 | 2007-12-05 | Bayer Schering Pharma Aktiengesellschaft | Kristallines 11beta-(4-Acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-on |
GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
EP2037938A2 (de) * | 2006-07-12 | 2009-03-25 | Controlled Therapeutics (Scotland) Ltd. | Arzneiabgabe-polymer mit clindamycin-hydrochloridsalz |
GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
MX343130B (es) | 2006-10-24 | 2016-10-26 | Repros Therapeutics Inc | Composiciones y métodos para suprimir la proliferación endometrial. |
TWI455716B (zh) * | 2006-10-24 | 2014-10-11 | Repros Therapeutics Inc | 選擇性黃體激素受體調節劑用於製造治療雌激素依賴性病症之藥物的用途 |
WO2008129396A2 (en) * | 2007-04-20 | 2008-10-30 | Preglem S.A. | Progesterone antagonist and selective progesterone modulator in the treatment of uterine bleeding |
US8299050B2 (en) | 2008-01-29 | 2012-10-30 | Laboratoire Hra-Pharma | Method for treating uterine fibroids |
LT2249757T (lt) | 2008-02-04 | 2017-09-25 | Ferring B.V. | Vientisi intravaginaliniai žiedai, apimantys progesteroną, ir jų gamybos bei panaudojimo būdai |
TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
US9034365B2 (en) | 2008-05-20 | 2015-05-19 | Poly-Med, Inc. | Biostable, multipurpose, microbicidal intravaginal devices |
EP2419109B1 (de) | 2009-04-14 | 2016-04-13 | Laboratoire HRA-Pharma | Verfahren zur bedarfsweisen kontrazeption mit levonorgestrel oder norgestrel |
NZ595790A (en) | 2009-04-14 | 2013-11-29 | Hra Pharma Lab | Method for on-demand contraception |
US20120070476A1 (en) * | 2009-05-29 | 2012-03-22 | Moench Thomas R | Compositions and Methods for Inactivation of Pathogens at Genital Tract Surfaces |
DE102009034367A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102009034368A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034362A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034366A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034525A1 (de) | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034526A1 (de) | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102010007722A1 (de) * | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
DE102010007719A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
KR20130009990A (ko) * | 2010-03-22 | 2013-01-24 | 레프로스 쎄라피우틱스 아이엔씨. | 항프로게스틴의 비독성 전달을 위한 조성물들과 그 방법들 |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
DE102011004899A1 (de) | 2011-03-01 | 2012-09-06 | Bayer Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE202011110355U1 (de) * | 2011-03-09 | 2014-01-15 | Arstat, Inc. | Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes |
EP2545922A1 (de) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Behandlung von übermäßiger Monatsblutung im Zusammenhang mit Gebärmutterfibromen |
IL215224A0 (en) * | 2011-09-18 | 2012-02-29 | Katz Daniel Dr | Vaginal danazol combined with non steroidal anti inflammatory drugs (nsaids) compositions |
WO2013098591A1 (es) * | 2011-12-29 | 2013-07-04 | Laboratorios Andrómaco S.A. | Anillo vaginal que comprende meloxicam y un agente modulador de la liberación del principio activo, útil como anticonceptivo de uso continuo en mujeres |
FR2987271B1 (fr) * | 2012-02-28 | 2017-08-18 | Hra Pharma Lab | Combinaison de modulateurs selectifs du recepteur a la progesterone et d'anti-inflammatoires non steroidiens |
EP2641602A1 (de) | 2012-03-23 | 2013-09-25 | PregLem S.A. | Verfahren zur Behandlung gynäkologischer Leiden |
SG10201704858PA (en) | 2012-05-31 | 2017-07-28 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
WO2014050105A1 (en) * | 2012-09-28 | 2014-04-03 | Aska Pharmaceutical Co., Ltd. | Amorphous ulipristal acetate |
EP2914268B1 (de) | 2012-11-02 | 2018-07-04 | Repros Therapeutics Inc. | Verfahren und zusammensetzungen zur behandlung von progesteronbedingten zuständen |
FR2997627B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant de l'ulipristal acetate |
FR2997628B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone |
FR2999081B1 (fr) | 2012-12-06 | 2015-02-27 | Hra Pharma Lab | Dispersion solide d'un modulateur selectif du recepteur a la progesterone |
JP6249790B2 (ja) | 2013-01-29 | 2017-12-20 | 三菱鉛筆株式会社 | シャープペンシル |
SG11201507260QA (en) | 2013-04-10 | 2015-10-29 | Preglem Sa | Progesteron receptor modulators for use in the therapy of uterine fibroids |
RS58277B1 (sr) | 2013-04-11 | 2019-03-29 | Bayer Pharma Aktiengesellshaft | Oblici doziranja antagonista receptora progesterona |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
DE102014004388A1 (de) * | 2014-03-26 | 2015-10-01 | Angela Kayser | Verfahren und System zum intravaginalen Verabreichen von Progesteron |
US20170020718A1 (en) * | 2014-04-01 | 2017-01-26 | Poly-Med, Inc. | Contraceptive and related device |
ES2699003T3 (es) | 2014-06-28 | 2019-02-06 | Laboratorios Andromaco S A | Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, usado para la prevención de partos prematuros |
MX2017005163A (es) | 2014-11-17 | 2018-01-18 | Arno Therapeutics Inc | Composiciones de liberación prolongada de onapristona y métodos. |
BR112018005999A2 (pt) | 2015-09-25 | 2019-01-08 | Context Biopharma Inc | métodos para a produção de intermediários de onapristona |
JP2019503353A (ja) * | 2015-12-15 | 2019-02-07 | コンテキスト・バイオファーマ・インコーポレイテッド | 非晶質オナプリストン組成物およびそれを作製する方法 |
US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
CN114073792A (zh) * | 2020-08-11 | 2022-02-22 | 上海市生物医药技术研究院 | 含来曲唑的阴道环、其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
US3948254A (en) * | 1971-11-08 | 1976-04-06 | Alza Corporation | Novel drug delivery device |
US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
DE69702450T2 (de) * | 1996-05-01 | 2001-03-08 | Us Gov Nat Inst Health | 21-substituierte progesteron derivate als antigestagene |
US5972372A (en) | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
US6358947B1 (en) * | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
FR2822022B1 (fr) | 2001-03-19 | 2005-11-04 | Atofina | Traitement pesticide des sols agricoles avec des composes soufres |
CN1210079C (zh) * | 2001-04-25 | 2005-07-13 | 上海市计划生育科学研究所 | 阴道环制剂及其应用 |
AU2004233997C1 (en) | 2003-04-29 | 2014-01-30 | Massachusetts Institiute Of Technology | Methods and devices for the sustained release of multiple drugs |
GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits |
-
2005
- 2005-07-08 CN CN2005800274481A patent/CN101080205B/zh active Active
- 2005-07-08 AU AU2005265357A patent/AU2005265357B2/en not_active Ceased
- 2005-07-08 WO PCT/US2005/024474 patent/WO2006010097A2/en active Application Filing
- 2005-07-08 CA CA2573266A patent/CA2573266C/en active Active
- 2005-07-08 PT PT05771439T patent/PT1768625E/pt unknown
- 2005-07-08 JP JP2007520580A patent/JP5017109B2/ja not_active Expired - Fee Related
- 2005-07-08 NZ NZ552720A patent/NZ552720A/en not_active IP Right Cessation
- 2005-07-08 MX MX2007000273A patent/MX2007000273A/es active IP Right Grant
- 2005-07-08 US US11/631,877 patent/US8865200B2/en active Active
- 2005-07-08 KR KR1020077002979A patent/KR101229701B1/ko active IP Right Grant
- 2005-07-08 DE DE602005026290T patent/DE602005026290D1/de active Active
- 2005-07-08 AT AT05771439T patent/ATE497745T1/de active
- 2005-07-08 DK DK05771439.6T patent/DK1768625T3/da active
- 2005-07-08 EP EP05771439A patent/EP1768625B1/de active Active
- 2005-07-08 ES ES05771439T patent/ES2360806T3/es active Active
- 2005-07-08 BR BRPI0513141-3A patent/BRPI0513141A/pt not_active Application Discontinuation
-
2011
- 2011-10-03 JP JP2011219461A patent/JP2012040400A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2008505718A (ja) | 2008-02-28 |
KR101229701B1 (ko) | 2013-02-05 |
ES2360806T3 (es) | 2011-06-09 |
JP2012040400A (ja) | 2012-03-01 |
NZ552720A (en) | 2010-02-26 |
WO2006010097A3 (en) | 2006-08-10 |
PT1768625E (pt) | 2011-04-18 |
MX2007000273A (es) | 2007-05-21 |
JP5017109B2 (ja) | 2012-09-05 |
DE602005026290D1 (de) | 2011-03-24 |
CA2573266A1 (en) | 2006-01-26 |
AU2005265357A1 (en) | 2006-01-26 |
US20080199511A1 (en) | 2008-08-21 |
EP1768625A2 (de) | 2007-04-04 |
DK1768625T3 (da) | 2011-05-09 |
WO2006010097A2 (en) | 2006-01-26 |
CA2573266C (en) | 2011-11-08 |
US8865200B2 (en) | 2014-10-21 |
CN101080205A (zh) | 2007-11-28 |
CN101080205B (zh) | 2011-10-12 |
BRPI0513141A (pt) | 2008-04-29 |
KR20070044005A (ko) | 2007-04-26 |
EP1768625B1 (de) | 2011-02-09 |
EP1768625A4 (de) | 2008-07-09 |
AU2005265357B2 (en) | 2011-04-07 |
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