BRPI0513141A - composição para anel vaginal, e, processo de contracepção a longo prazo - Google Patents
composição para anel vaginal, e, processo de contracepção a longo prazoInfo
- Publication number
- BRPI0513141A BRPI0513141A BRPI0513141-3A BRPI0513141A BRPI0513141A BR PI0513141 A BRPI0513141 A BR PI0513141A BR PI0513141 A BRPI0513141 A BR PI0513141A BR PI0513141 A BRPI0513141 A BR PI0513141A
- Authority
- BR
- Brazil
- Prior art keywords
- long
- vaginal ring
- ring composition
- term contraceptive
- term
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
COMPOSIçãO PARA ANEL VAGINAL, E, PROCESSO DE CONTRACEPçãO A LONGO PRAZO São divulgadas composições para liberação prolongada para administração vaginal ou transdermal que contêm um modulador do receptor de progesterona tal como CDB-2914 (também denominado VA-29 14) e processos de utilização das mesmas para contracepção a longo prazo ou para fins terapêuticos. Também são divulgados processos pra a obtenção das composições.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58678304P | 2004-07-09 | 2004-07-09 | |
PCT/US2005/024474 WO2006010097A2 (en) | 2004-07-09 | 2005-07-08 | Sustained release compositions containing progesterone receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0513141A true BRPI0513141A (pt) | 2008-04-29 |
Family
ID=35785781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0513141-3A BRPI0513141A (pt) | 2004-07-09 | 2005-07-08 | composição para anel vaginal, e, processo de contracepção a longo prazo |
Country Status (16)
Country | Link |
---|---|
US (1) | US8865200B2 (pt) |
EP (1) | EP1768625B1 (pt) |
JP (2) | JP5017109B2 (pt) |
KR (1) | KR101229701B1 (pt) |
CN (1) | CN101080205B (pt) |
AT (1) | ATE497745T1 (pt) |
AU (1) | AU2005265357B2 (pt) |
BR (1) | BRPI0513141A (pt) |
CA (1) | CA2573266C (pt) |
DE (1) | DE602005026290D1 (pt) |
DK (1) | DK1768625T3 (pt) |
ES (1) | ES2360806T3 (pt) |
MX (1) | MX2007000273A (pt) |
NZ (1) | NZ552720A (pt) |
PT (1) | PT1768625E (pt) |
WO (1) | WO2006010097A2 (pt) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436428B1 (en) * | 2000-03-21 | 2002-08-20 | Enhance Pharmaceuticals, Inc. | Device and method for treating urinary incontinence in females |
GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
US8404272B2 (en) | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
US8399013B2 (en) | 2003-06-26 | 2013-03-19 | Poly-Med, Inc. | Partially absorbable fiber-reinforced composites for controlled drug delivery |
GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
US8062658B2 (en) * | 2004-12-14 | 2011-11-22 | Poly-Med, Inc. | Multicomponent bioactive intravaginal ring |
EP1862468A1 (de) | 2006-06-02 | 2007-12-05 | Bayer Schering Pharma Aktiengesellschaft | Kristallines 11beta-(4-Acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-on |
GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
CN101500583B (zh) * | 2006-07-12 | 2012-05-23 | 控制治疗(苏格兰)有限公司 | 含克林霉素盐酸盐的药物递送聚合物 |
GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
TWI455716B (zh) * | 2006-10-24 | 2014-10-11 | Repros Therapeutics Inc | 選擇性黃體激素受體調節劑用於製造治療雌激素依賴性病症之藥物的用途 |
EP3693376A1 (en) * | 2006-10-24 | 2020-08-12 | Allergan Pharmaceuticals International Limited | Compositions for suppressing endometrial proliferation |
DK2148681T3 (en) * | 2007-04-20 | 2016-07-04 | Preglem Sa | Selective progesteronmodulatorer in the treatment of uterine bleeding |
US8299050B2 (en) | 2008-01-29 | 2012-10-30 | Laboratoire Hra-Pharma | Method for treating uterine fibroids |
DK2249757T3 (en) * | 2008-02-04 | 2017-10-16 | Ferring Bv | Monolithic vaginal rings comprising progesterone and methods of preparation and use thereof. |
TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
US9034365B2 (en) | 2008-05-20 | 2015-05-19 | Poly-Med, Inc. | Biostable, multipurpose, microbicidal intravaginal devices |
LT2419108T (lt) | 2009-04-14 | 2016-12-27 | Laboratoire Hra Pharma | Kontracepcijos pagal poreikį būdas |
CA2758764C (en) | 2009-04-14 | 2017-04-11 | Elizabeth Gray Raymond | Method for on-demand contraception using levonorgestrel or norgestrel |
US20120070476A1 (en) * | 2009-05-29 | 2012-03-22 | Moench Thomas R | Compositions and Methods for Inactivation of Pathogens at Genital Tract Surfaces |
DE102009034368A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034366A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034362A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034367A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102009034525A1 (de) | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034526A1 (de) | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102010007722A1 (de) * | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
DE102010007719A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
EP2550288A1 (en) * | 2010-03-22 | 2013-01-30 | Repros Therapeutics Inc. | Compositions and methods for non-toxic delivery of antiprogestins |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
DE102011004899A1 (de) | 2011-03-01 | 2012-09-06 | Bayer Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE202011110355U1 (de) * | 2011-03-09 | 2014-01-15 | Arstat, Inc. | Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes |
EP2545922A1 (en) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Treatment of excessive menstrual bleeding associated with uterine fibroids |
IL215224A0 (en) * | 2011-09-18 | 2012-02-29 | Katz Daniel Dr | Vaginal danazol combined with non steroidal anti inflammatory drugs (nsaids) compositions |
WO2013098591A1 (es) * | 2011-12-29 | 2013-07-04 | Laboratorios Andrómaco S.A. | Anillo vaginal que comprende meloxicam y un agente modulador de la liberación del principio activo, útil como anticonceptivo de uso continuo en mujeres |
FR2987271B1 (fr) * | 2012-02-28 | 2017-08-18 | Hra Pharma Lab | Combinaison de modulateurs selectifs du recepteur a la progesterone et d'anti-inflammatoires non steroidiens |
EP2641602A1 (en) | 2012-03-23 | 2013-09-25 | PregLem S.A. | Method for treating gynecological diseases |
BR112014029131B1 (pt) | 2012-05-31 | 2021-03-09 | Allergan Pharmaceuticals International Limited | cápsula de mucoadesivo |
WO2014050105A1 (en) * | 2012-09-28 | 2014-04-03 | Aska Pharmaceutical Co., Ltd. | Amorphous ulipristal acetate |
CA2888377C (en) | 2012-11-02 | 2021-02-02 | Repros Therapeutics Inc. | Methods and compositions for treating progesterone-dependent conditions |
FR2997628B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone |
FR2997627B1 (fr) | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant de l'ulipristal acetate |
FR2999081B1 (fr) | 2012-12-06 | 2015-02-27 | Hra Pharma Lab | Dispersion solide d'un modulateur selectif du recepteur a la progesterone |
JP6249790B2 (ja) | 2013-01-29 | 2017-12-20 | 三菱鉛筆株式会社 | シャープペンシル |
UY35528A (es) | 2013-04-10 | 2014-09-30 | Preglem Sa | Moduladores del receptor de la progesterona para uso en la terapia de fibromas uterinos |
HUE042368T2 (hu) | 2013-04-11 | 2019-06-28 | Bayer Pharma AG | Progeszteronreceptor-antagonista dózisformája |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
DE102014004388A1 (de) * | 2014-03-26 | 2015-10-01 | Angela Kayser | Verfahren und System zum intravaginalen Verabreichen von Progesteron |
CA3208334A1 (en) * | 2014-04-01 | 2015-10-08 | Poly-Med, Inc. | Contraceptive and related device |
WO2015198104A1 (es) | 2014-06-28 | 2015-12-30 | Laboratorios Andromaco S.A. | Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro |
US10786461B2 (en) | 2014-11-17 | 2020-09-29 | Context Biopharma Inc. | Onapristone extended-release compositions and methods |
BR112018005999A2 (pt) | 2015-09-25 | 2019-01-08 | Context Biopharma Inc | métodos para a produção de intermediários de onapristona |
KR20180113988A (ko) | 2015-12-15 | 2018-10-17 | 컨텍스트 바이오파마 인코포레이티드 | 비정질 오나프리스톤 조성물 및 그 제조방법 |
US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
CN114073792A (zh) * | 2020-08-11 | 2022-02-22 | 上海市生物医药技术研究院 | 含来曲唑的阴道环、其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
US3948254A (en) * | 1971-11-08 | 1976-04-06 | Alza Corporation | Novel drug delivery device |
US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
CA2253673C (en) * | 1996-05-01 | 2009-09-08 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | 21-substituted progesterone derivatives as new antiprogestational agents |
US5972372A (en) | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
US6358947B1 (en) * | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
FR2822022B1 (fr) | 2001-03-19 | 2005-11-04 | Atofina | Traitement pesticide des sols agricoles avec des composes soufres |
CN1210079C (zh) * | 2001-04-25 | 2005-07-13 | 上海市计划生育科学研究所 | 阴道环制剂及其应用 |
EP1620060B1 (en) | 2003-04-29 | 2010-03-24 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits |
-
2005
- 2005-07-08 BR BRPI0513141-3A patent/BRPI0513141A/pt not_active Application Discontinuation
- 2005-07-08 WO PCT/US2005/024474 patent/WO2006010097A2/en active Application Filing
- 2005-07-08 NZ NZ552720A patent/NZ552720A/en not_active IP Right Cessation
- 2005-07-08 AU AU2005265357A patent/AU2005265357B2/en not_active Ceased
- 2005-07-08 US US11/631,877 patent/US8865200B2/en active Active
- 2005-07-08 MX MX2007000273A patent/MX2007000273A/es active IP Right Grant
- 2005-07-08 AT AT05771439T patent/ATE497745T1/de active
- 2005-07-08 DK DK05771439.6T patent/DK1768625T3/da active
- 2005-07-08 CN CN2005800274481A patent/CN101080205B/zh not_active Expired - Fee Related
- 2005-07-08 PT PT05771439T patent/PT1768625E/pt unknown
- 2005-07-08 CA CA2573266A patent/CA2573266C/en active Active
- 2005-07-08 KR KR1020077002979A patent/KR101229701B1/ko active IP Right Grant
- 2005-07-08 ES ES05771439T patent/ES2360806T3/es active Active
- 2005-07-08 EP EP05771439A patent/EP1768625B1/en active Active
- 2005-07-08 DE DE602005026290T patent/DE602005026290D1/de active Active
- 2005-07-08 JP JP2007520580A patent/JP5017109B2/ja not_active Expired - Fee Related
-
2011
- 2011-10-03 JP JP2011219461A patent/JP2012040400A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2360806T3 (es) | 2011-06-09 |
CN101080205A (zh) | 2007-11-28 |
CN101080205B (zh) | 2011-10-12 |
MX2007000273A (es) | 2007-05-21 |
JP2008505718A (ja) | 2008-02-28 |
JP5017109B2 (ja) | 2012-09-05 |
PT1768625E (pt) | 2011-04-18 |
NZ552720A (en) | 2010-02-26 |
US8865200B2 (en) | 2014-10-21 |
KR20070044005A (ko) | 2007-04-26 |
EP1768625B1 (en) | 2011-02-09 |
AU2005265357A1 (en) | 2006-01-26 |
AU2005265357B2 (en) | 2011-04-07 |
ATE497745T1 (de) | 2011-02-15 |
EP1768625A2 (en) | 2007-04-04 |
WO2006010097A3 (en) | 2006-08-10 |
CA2573266A1 (en) | 2006-01-26 |
DE602005026290D1 (de) | 2011-03-24 |
US20080199511A1 (en) | 2008-08-21 |
JP2012040400A (ja) | 2012-03-01 |
EP1768625A4 (en) | 2008-07-09 |
DK1768625T3 (da) | 2011-05-09 |
CA2573266C (en) | 2011-11-08 |
WO2006010097A2 (en) | 2006-01-26 |
KR101229701B1 (ko) | 2013-02-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |