SI1989218T1 - 17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji - Google Patents

17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji

Info

Publication number
SI1989218T1
SI1989218T1 SI200730188T SI200730188T SI1989218T1 SI 1989218 T1 SI1989218 T1 SI 1989218T1 SI 200730188 T SI200730188 T SI 200730188T SI 200730188 T SI200730188 T SI 200730188T SI 1989218 T1 SI1989218 T1 SI 1989218T1
Authority
SI
Slovenia
Prior art keywords
steroid derivatives
receptor modulators
progesterone receptor
derivatives useful
phosphorous
Prior art date
Application number
SI200730188T
Other languages
English (en)
Inventor
Weiqin Jiang
Zhihua Sui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SI1989218T1 publication Critical patent/SI1989218T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
SI200730188T 2006-02-17 2007-02-16 17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji SI1989218T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77504306P 2006-02-17 2006-02-17
EP07757086A EP1989218B1 (en) 2006-02-17 2007-02-16 17-phosphorous steroid derivatives useful as progesterone receptor modulators

Publications (1)

Publication Number Publication Date
SI1989218T1 true SI1989218T1 (sl) 2010-04-30

Family

ID=38330971

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200730188T SI1989218T1 (sl) 2006-02-17 2007-02-16 17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji

Country Status (15)

Country Link
US (1) US7671045B2 (sl)
EP (1) EP1989218B1 (sl)
JP (1) JP5230450B2 (sl)
CN (1) CN101421290B (sl)
AT (1) ATE453660T1 (sl)
AU (1) AU2007217095B2 (sl)
CA (1) CA2642566C (sl)
CY (1) CY1111128T1 (sl)
DE (1) DE602007004081D1 (sl)
DK (1) DK1989218T3 (sl)
ES (1) ES2337521T3 (sl)
PL (1) PL1989218T3 (sl)
PT (1) PT1989218E (sl)
SI (1) SI1989218T1 (sl)
WO (1) WO2007098382A2 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0501132A2 (en) * 2005-12-05 2007-06-28 Richter Gedeon Nyrt 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
PL1989217T4 (pl) * 2006-02-17 2013-02-28 Janssen Pharmaceutica Nv 11-fosforowe pochodne steroidowe użyteczne jako modulatory receptora progesteronu
AU2008222829A1 (en) 2007-03-07 2008-09-12 Janssen Pharmaceutica N.V. Steroids derivatives as selective progesterone receptor modulators
CN102617691B (zh) * 2012-01-18 2014-05-14 上海新华联制药有限公司 一种改进的米非司酮中间体制备方法
WO2014060888A1 (en) 2012-10-18 2014-04-24 Lupin Limited Novel process and intermediate for preparation of ulipristal
CA3009522A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
CA3009525A1 (en) 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6801093B2 (ja) 2016-10-07 2020-12-16 オリック ファーマシューティカルズ，インク． グルココルチコイド受容体の阻害剤
CN106810584A (zh) * 2016-12-28 2017-06-09 宁波第二激素厂 烯丙孕素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
GB9003939D0 (en) * 1990-02-21 1990-04-18 Imperial College Sulphatase inhibitors
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
CA2100514C (en) 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
JPH0995496A (ja) * 1995-09-28 1997-04-08 Kaken Pharmaceut Co Ltd ウルソデオキシコール酸誘導体
EP1448592B1 (en) * 2001-10-18 2006-03-08 Sterix Limited Steroidal compounds for inhibiting steroid sulphatase

Also Published As

Publication number Publication date
DE602007004081D1 (de) 2010-02-11
CA2642566A1 (en) 2007-08-30
AU2007217095A1 (en) 2007-08-30
US7671045B2 (en) 2010-03-02
ES2337521T3 (es) 2010-04-26
PT1989218E (pt) 2010-02-01
AU2007217095B2 (en) 2012-05-03
PL1989218T3 (pl) 2010-06-30
CN101421290B (zh) 2012-09-19
WO2007098382A3 (en) 2007-11-01
DK1989218T3 (da) 2010-04-26
WO2007098382A2 (en) 2007-08-30
CY1111128T1 (el) 2015-06-11
ATE453660T1 (de) 2010-01-15
EP1989218B1 (en) 2009-12-30
JP5230450B2 (ja) 2013-07-10
CN101421290A (zh) 2009-04-29
CA2642566C (en) 2014-04-15
US20070207982A1 (en) 2007-09-06
EP1989218A2 (en) 2008-11-12
JP2009527490A (ja) 2009-07-30

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