|
AU2006232287B2
(en)
|
2005-03-31 |
2011-10-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing polypeptides by regulating polypeptide association
|
|
CN104761637B
(zh)
|
2006-03-31 |
2021-10-15 |
中外制药株式会社 |
调控抗体血液动力学的方法
|
|
EP2009101B1
(en)
|
2006-03-31 |
2017-10-25 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
|
ES2595638T3
(es)
|
2007-09-26 |
2017-01-02 |
Chugai Seiyaku Kabushiki Kaisha |
Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR
|
|
KR101680906B1
(ko)
|
2007-09-26 |
2016-11-30 |
추가이 세이야쿠 가부시키가이샤 |
항체 정상영역 개변체
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
WO2011108714A1
(ja)
|
2010-03-04 |
2011-09-09 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
AU2011283694B2
(en)
|
2010-07-29 |
2017-04-13 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
TWI452136B
(zh)
|
2010-11-17 |
2014-09-11 |
中外製藥股份有限公司 |
A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation
|
|
PT3434767T
(pt)
|
2010-11-30 |
2026-01-23 |
Chugai Pharmaceutical Co Ltd |
Agente terapêutico indutor de citotoxicidade
|
|
BR112013023918A2
(pt)
*
|
2011-03-25 |
2016-12-13 |
Glenmark Pharmaceuticals Sa |
imunoglobulina hetero-dimérica ou fragmento hetero-dimérico da mesma, método para produzir uma imunoglobulina hetero-dimérica ou fragmento hetero-dimérico da mesma, método para construir uma interface proteína-proteína de um domínio de uma proteína de múltiplos domínios e uso de um domínio doador de um primeiro e de um segundo membro de uma super-família de imunoglobulina de ocorrência natural
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
EP2892924B1
(en)
*
|
2012-06-14 |
2020-11-25 |
Therapix Biosciences Ltd. |
Humanized antibodies to cluster of differentiation 3 (cd3)
|
|
AU2013322710A1
(en)
*
|
2012-09-25 |
2015-04-16 |
Glenmark Pharmaceuticals S.A. |
Purification of hetero-dimeric immunoglobulins
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
KR102211837B1
(ko)
|
2013-01-14 |
2021-02-03 |
젠코어 인코포레이티드 |
신규한 이형이량체 단백질
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
CN105283201B
(zh)
|
2013-03-14 |
2019-08-02 |
斯克利普斯研究所 |
靶向剂抗体偶联物及其用途
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP2970486B1
(en)
|
2013-03-15 |
2018-05-16 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
ES2881306T3
(es)
|
2013-09-27 |
2021-11-29 |
Chugai Pharmaceutical Co Ltd |
Método para la producción de heteromultímeros de polipéptidos
|
|
JP2016538275A
(ja)
|
2013-11-04 |
2016-12-08 |
グレンマーク ファーマシューティカルズ, エセ.アー. |
T細胞再標的化ヘテロ二量体免疫グロブリン(hetero−dimeric immunoglobulin)の製造
|
|
IL263466B2
(en)
|
2013-12-17 |
2023-10-01 |
Genentech Inc |
Anti-CD3 antibodies and methods of using them
|
|
EP3699195A3
(en)
*
|
2014-03-28 |
2020-11-04 |
Xencor, Inc. |
Bispecific antibodies that bind to cd38 and cd3
|
|
AU2015244814B2
(en)
|
2014-04-07 |
2020-12-24 |
Chugai Seiyaku Kabushiki Kaisha |
Immunoactivating antigen-binding molecule
|
|
MX2016014434A
(es)
|
2014-05-13 |
2017-02-23 |
Chugai Pharmaceutical Co Ltd |
Molecula de union a antigeno redirigida a celulas t para celulas que tienen funcion de inmunosupresion.
|
|
MA40579A
(fr)
|
2014-09-12 |
2016-03-17 |
Genentech Inc |
Anticorps anti-cll-1 et immunoconjugués
|
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
|
MA40894A
(fr)
*
|
2014-11-04 |
2017-09-12 |
Glenmark Pharmaceuticals Sa |
Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
|
|
EP3223907A2
(en)
|
2014-11-26 |
2017-10-04 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
|
PE20171324A1
(es)
|
2014-11-26 |
2017-09-11 |
Xencor Inc |
Anticuerpos heterodimericos que se unen a cd3 y a antigenos tumorales
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
|
JP7237449B2
(ja)
*
|
2015-02-27 |
2023-03-13 |
アイセル・ジーン・セラピューティクス・エルエルシー |
血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
JP7082484B2
(ja)
|
2015-04-01 |
2022-06-08 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
|
GB201506868D0
(en)
*
|
2015-04-22 |
2015-06-03 |
Ucb Biopharma Sprl |
Method for protein purification
|
|
SG11201708804WA
(en)
|
2015-05-07 |
2017-11-29 |
Agenus Inc |
Anti-ox40 antibodies and methods of use thereof
|
|
DK3310814T5
(da)
|
2015-06-16 |
2024-10-07 |
Hoffmann La Roche |
Humaniserede og affinitetsmodnede antistoffer mod FcRH5 og fremgangsmåder til anvendelse
|
|
EP3916018A1
(en)
|
2015-06-16 |
2021-12-01 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
US10501545B2
(en)
|
2015-06-16 |
2019-12-10 |
Genentech, Inc. |
Anti-CLL-1 antibodies and methods of use
|
|
HUE057952T2
(hu)
|
2015-06-24 |
2022-06-28 |
Hoffmann La Roche |
Anti-transzferrin receptor antitestek testreszabott affinitással
|
|
US11655452B2
(en)
|
2015-06-25 |
2023-05-23 |
Icell Gene Therapeutics Inc. |
Chimeric antigen receptors (CARs), compositions and methods of use thereof
|
|
US11173179B2
(en)
|
2015-06-25 |
2021-11-16 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof
|
|
IL319047A
(en)
|
2015-08-28 |
2025-04-01 |
Amunix Operating Inc |
Chimeric polypeptide composition and methods for its preparation and use
|
|
TWI873952B
(zh)
|
2015-10-02 |
2025-02-21 |
瑞士商赫孚孟拉羅股份公司 |
雙特異性抗‐人類cd20/人類轉鐵蛋白受體抗體及使用方法
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
RS62437B1
(sr)
|
2015-10-25 |
2021-11-30 |
Sanofi Sa |
Trispecifični i/ili trivalentni vezujući proteini za prevenciju ili lečenje hiv infekcije
|
|
WO2017086419A1
(ja)
*
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
|
WO2017086367A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
|
CN108883173B
(zh)
|
2015-12-02 |
2022-09-06 |
阿吉纳斯公司 |
抗体和其使用方法
|
|
CA3007030A1
(en)
|
2015-12-07 |
2017-06-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
WO2017107973A1
(zh)
*
|
2015-12-24 |
2017-06-29 |
凯惠科技发展(上海)有限公司 |
一种tpbg抗体及其制备方法、其偶联物和应用
|
|
AU2016381992B2
(en)
*
|
2015-12-28 |
2024-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
|
KR102891788B1
(ko)
|
2016-02-04 |
2025-11-26 |
더 스크립스 리서치 인스티튜트 |
인간화 항-cd3 항체, 접합체 및 이의 용도
|
|
PT3433273T
(pt)
|
2016-03-25 |
2022-02-21 |
Biomunex Pharmaceuticals |
Moléculas de ligação a cd38 e pd-l1
|
|
LT3443006T
(lt)
|
2016-04-13 |
2023-10-25 |
Sanofi |
Trispecifiniai ir (arba) trivalenčiai rišantieji baltymai
|
|
CA3020633A1
(en)
|
2016-04-13 |
2017-10-19 |
Sanofi |
Trispecific and/or trivalent binding proteins
|
|
CR20180554A
(es)
|
2016-04-28 |
2019-01-10 |
Chugai Pharmaceutical Co Ltd |
Preparaciones que contienen anticuerpos
|
|
SG11201809316XA
(en)
|
2016-04-28 |
2018-11-29 |
Biomunex Pharmaceuticals |
Bispecific antibodies targeting egfr and her2
|
|
JP7010854B2
(ja)
|
2016-06-14 |
2022-01-26 |
ゼンコア インコーポレイテッド |
二重特異性チェックポイント阻害剤抗体
|
|
KR20250175345A
(ko)
|
2016-06-21 |
2025-12-16 |
테네오바이오, 인코포레이티드 |
Cd3 결합 항체
|
|
CN109562126A
(zh)
|
2016-06-24 |
2019-04-02 |
美商生物细胞基因治疗有限公司 |
嵌合抗原受体(car)、组合物及其使用方法
|
|
CN109715663B
(zh)
|
2016-06-28 |
2022-11-25 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
|
KR102579850B1
(ko)
*
|
2016-07-22 |
2023-09-18 |
암젠 인크 |
Fc-함유 단백질의 정제 방법
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
PE20241349A1
(es)
|
2016-09-14 |
2024-07-03 |
Teneobio Inc |
Anticuerpos de union a cd3
|
|
ES2981272T3
(es)
|
2016-09-23 |
2024-10-08 |
Merus Nv |
Moléculas de unión que modulan una actividad biológica expresada por una célula
|
|
CN106632681B
(zh)
*
|
2016-10-11 |
2017-11-14 |
北京东方百泰生物科技有限公司 |
抗egfr和抗cd3双特异抗体及其应用
|
|
MY203000A
(en)
|
2016-10-14 |
2024-06-01 |
Xencor Inc |
Il15/il15r� heterodimeric fc-fusion proteins
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
JP7784795B2
(ja)
|
2016-11-15 |
2025-12-12 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体による処置のための投与
|
|
IL317134A
(en)
|
2016-12-21 |
2025-01-01 |
Teneobio Inc |
An antibody containing only heavy chains that binds a human B-cell maturation antigen, a pharmaceutical composition containing the same, its use in the treatment of B-cell disorders and a method for its preparation
|
|
CN106749678A
(zh)
*
|
2017-01-09 |
2017-05-31 |
北京普瑞金科技有限公司 |
Her2 car重组慢病毒载体及其构建方法与应用
|
|
KR20240125061A
(ko)
|
2017-03-27 |
2024-08-19 |
바이오뮤넥스 파마슈티컬스 |
안정적인 다중특이적 항체
|
|
CN110461358A
(zh)
|
2017-03-31 |
2019-11-15 |
公立大学法人奈良县立医科大学 |
可用于预防和/或治疗凝血因子ⅸ异常、包含代替凝血因子ⅷ的功能的多特异性抗原结合分子的药物组合物
|
|
CA3060190A1
(en)
*
|
2017-04-24 |
2018-11-01 |
Ichnos Sciences SA |
T cell redirecting bispecific antibodies for the treatment of egfr positive cancers
|
|
EP3409322A1
(en)
|
2017-06-01 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Treatment method
|
|
WO2018224441A1
(en)
*
|
2017-06-05 |
2018-12-13 |
Numab Innovation Ag |
Novel anti-cd3 antibodies
|
|
EP3634998B8
(en)
*
|
2017-06-05 |
2025-04-09 |
Numab Therapeutics AG |
Anti-cd3 epsilon antibodies
|
|
KR20200014379A
(ko)
*
|
2017-06-05 |
2020-02-10 |
얀센 바이오테크 인코포레이티드 |
비대칭 ch2-ch3 영역 돌연변이를 갖는 조작된 다중특이성 항체 및 다른 다량체 단백질
|
|
CN110945026B
(zh)
|
2017-06-20 |
2024-03-19 |
特纳奥尼股份有限公司 |
仅有重链的抗bcma抗体
|
|
KR20250007003A
(ko)
|
2017-06-20 |
2025-01-13 |
테네오바이오, 인코포레이티드 |
항-bcma 중쇄-단독 항체
|
|
CA3287539A1
(en)
|
2017-06-21 |
2026-03-02 |
Icell Gene Therapeutics Llc |
CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF
|
|
WO2019006472A1
(en)
|
2017-06-30 |
2019-01-03 |
Xencor, Inc. |
TARGETED HETETRODIMERIC FUSION PROTEINS CONTAINING IL-15 / IL-15RA AND ANTIGEN-BINDING DOMAINS
|
|
WO2019034580A1
(en)
|
2017-08-14 |
2019-02-21 |
Morphosys Ag |
HUMANIZED ANTIBODIES FOR CD3
|
|
EP3681908A1
(en)
*
|
2017-09-13 |
2020-07-22 |
Teneobio, Inc. |
Heavy chain antibodies binding to ectoenzymes
|
|
BR112020007002A2
(pt)
|
2017-10-10 |
2020-11-17 |
Sanofi |
anticorpos anti-cd38 e métodos de uso
|
|
CN119161488A
(zh)
|
2017-11-01 |
2024-12-20 |
中外制药株式会社 |
具有降低的生物活性的抗体变体和同种型
|
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗pd−1配列を用いた二重特異性および単一特異性抗体
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CA3081854A1
(en)
|
2017-11-08 |
2019-05-16 |
Kyowa Kirin Co., Ltd. |
Bispecific antibody which binds to cd40 and epcam
|
|
IL275426B2
(en)
|
2017-12-19 |
2025-03-01 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
|
JP2021508479A
(ja)
*
|
2017-12-27 |
2021-03-11 |
テネオバイオ, インコーポレイテッド |
ヘテロ二量体特異的抗体上のcd3デルタ及びcd3イプシロン
|
|
EP3740505A1
(en)
*
|
2018-01-16 |
2020-11-25 |
Lakepharma Inc. |
Bispecific antibody that binds cd3 and another target
|
|
IL325995A
(en)
|
2018-02-08 |
2026-03-01 |
Genentech Inc |
Bispecific antigen binding molecules and methods of use
|
|
CN120399075A
(zh)
|
2018-03-14 |
2025-08-01 |
诺维莫尼公司 |
抗-CD3ε抗体及其应用方法
|
|
CN110305217B
(zh)
|
2018-03-27 |
2022-03-29 |
广州爱思迈生物医药科技有限公司 |
双特异性抗体及其应用
|
|
CA3096052A1
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
|
SG11202010163QA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
KR102602329B1
(ko)
*
|
2018-05-23 |
2023-11-16 |
화이자 인코포레이티드 |
Cd3에 특이적인 항체 및 이의 용도
|
|
WO2019224385A2
(en)
*
|
2018-05-24 |
2019-11-28 |
Glenmark Pharmaceuticals S.A. |
Combined bispecific antibody and immuno-oncology therapies
|
|
TW202016144A
(zh)
*
|
2018-06-21 |
2020-05-01 |
日商第一三共股份有限公司 |
包括cd3抗原結合片段之組成物及其用途
|
|
MY207066A
(en)
|
2018-08-17 |
2025-01-28 |
Regeneron Pharma |
Method and chromatography system for determining amount and purity of a multimeric protein
|
|
EP3620785A1
(en)
*
|
2018-09-07 |
2020-03-11 |
Ares Trading S.A. |
Electrophoresis-based characterization of fc fusion proteins
|
|
CA3113756A1
(en)
*
|
2018-09-25 |
2020-04-02 |
Ichnos Sciences S.A. |
Antibody quantification in biological samples
|
|
AU2019355971B2
(en)
|
2018-10-03 |
2025-05-08 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
|
JP7462621B2
(ja)
|
2018-10-09 |
2024-04-05 |
サノフイ |
三重特異性抗cd38、抗cd28、および抗cd3結合タンパク質ならびにウイルス感染を処置するための使用方法
|
|
KR20210086651A
(ko)
*
|
2018-10-26 |
2021-07-08 |
테네오바이오, 인코포레이티드 |
Cd38에 결합하는 중쇄 항체
|
|
WO2020112970A1
(en)
*
|
2018-11-30 |
2020-06-04 |
The Trustees Of The University Of Pennsylvania |
Bw6 specific car designed to protect transplanted tissue from rejection
|
|
EP3897719A4
(en)
|
2018-12-21 |
2022-11-02 |
Zhejiang Shimai Pharmaceutical Co., Ltd. |
Protease cleavable bispecific antibodies and uses thereof
|
|
CA3132185A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
EP3938403A1
(en)
|
2019-03-14 |
2022-01-19 |
F. Hoffmann-La Roche AG |
Treatment of cancer with her2xcd3 bispecific antibodies in combination with anti-her2 mab
|
|
JP2022525703A
(ja)
*
|
2019-03-20 |
2022-05-18 |
ジャベリン・オンコロジー・インコーポレイテッド |
抗adam12抗体およびキメラ抗原受容体、ならびにそれを含む組成物および方法
|
|
WO2020206330A1
(en)
|
2019-04-05 |
2020-10-08 |
Teneobio, Inc. |
Heavy chain antibodies binding to psma
|
|
KR102239781B1
(ko)
|
2019-04-08 |
2021-04-13 |
주식회사 녹십자 |
Gpnmb 및 cd3에 특이적으로 결합하는 이중특이적 항체 및 이의 용도
|
|
US11613576B2
(en)
|
2019-04-09 |
2023-03-28 |
Sanofi |
Trispecific binding proteins, methods, and uses thereof
|
|
WO2020232247A1
(en)
|
2019-05-14 |
2020-11-19 |
Provention Bio, Inc. |
Methods and compositions for preventing type 1 diabetes
|
|
TWI899079B
(zh)
*
|
2019-05-23 |
2025-10-01 |
美商維洛斯生物公司 |
抗ror1/抗cd3雙特異性結合分子
|
|
CR20210622A
(es)
|
2019-06-14 |
2022-06-27 |
Teneobio Inc |
Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3
|
|
US20220372098A1
(en)
*
|
2019-06-26 |
2022-11-24 |
The Johns Hopkins University |
Methods and materials for targeted expansion of immune effector cells
|
|
CN110551221B
(zh)
|
2019-07-02 |
2021-03-05 |
广州爱思迈生物医药科技有限公司 |
一种双特异性抗体及其制备方法与应用
|
|
US20220267469A1
(en)
*
|
2019-07-12 |
2022-08-25 |
Lipum Ab |
Novel bssl antibodies
|
|
EP3791931A1
(en)
*
|
2019-09-13 |
2021-03-17 |
Ichnos Sciences SA |
Bispecific antibodies for the treatment of solid tumors
|
|
TWI841790B
(zh)
*
|
2019-09-30 |
2024-05-11 |
大陸商和鉑醫藥(上海)有限責任公司 |
靶向cd3的抗體、雙特異性抗體及其用途
|
|
CN112876563B
(zh)
*
|
2019-11-29 |
2022-08-16 |
康诺亚生物医药科技(成都)有限公司 |
药物组合物及其制备方法和应用
|
|
CA3163017A1
(en)
*
|
2019-12-26 |
2021-07-01 |
Daehae SONG |
Method for purifying biologically active peptide by using protein a affinity chromatography
|
|
WO2021138380A2
(en)
*
|
2019-12-30 |
2021-07-08 |
University Of Louisville Research Foundation, Inc. |
Virus-like particle binding agents, related compositions, and related methods
|
|
CN115279796A
(zh)
*
|
2020-01-23 |
2022-11-01 |
天演药业(瑞士)公司 |
具有Fc突变的异二聚蛋白质
|
|
TWI888487B
(zh)
|
2020-02-14 |
2025-07-01 |
日商協和麒麟股份有限公司 |
與cd3結合之雙特異性抗體
|
|
JP7840569B2
(ja)
*
|
2020-02-17 |
2026-04-06 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
ヒト4-1bbアゴニスト抗体およびその使用方法
|
|
TWI908779B
(zh)
*
|
2020-03-17 |
2025-12-21 |
美商西雅圖免疫公司 |
引導及導航控制(gnc)抗體樣蛋白質及製造與使用其之方法
|
|
MX2023013382A
(es)
|
2020-04-04 |
2024-01-30 |
Janux Therapeutics Inc |
Composiciones y metodos relacionados con anticuerpos activados contra tumores dirigidos a egfr y antigenos de celulas efectoras.
|
|
WO2021222595A2
(en)
*
|
2020-04-30 |
2021-11-04 |
Virtuoso Binco, Inc. |
Multispecific antibodies targeting cd38 and epcam and uses thereof
|
|
CN116096754A
(zh)
|
2020-05-04 |
2023-05-09 |
免疫里森公司 |
前体三特异性抗体构建体及其使用方法
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
IL298999A
(en)
|
2020-06-11 |
2023-02-01 |
Provention Bio Inc |
Methods and compositions for the prevention of type 1 diabetes
|
|
US20240092903A1
(en)
*
|
2020-06-12 |
2024-03-21 |
Ichnos Sciences SA |
Antibody formulation diluent
|
|
JP7620780B2
(ja)
|
2020-06-30 |
2025-01-24 |
ノナ・バイオサイエンシーズ・(シャンハイ)・カンパニー・リミテッド |
H2L2とHCAb構造を有する結合タンパク質
|
|
EP4190813A4
(en)
*
|
2020-07-31 |
2025-02-12 |
Bio-Thera Solutions, Ltd. |
CD47 ANTIBODIES AND THEIR APPLICATION
|
|
US11197910B1
(en)
|
2020-08-19 |
2021-12-14 |
Vitruviae LLC |
Fusion proteins for the diagnosis, prophylaxis and treatment of infectious diseases
|
|
CA3192204A1
(en)
|
2020-08-19 |
2022-02-24 |
Xencor, Inc. |
Anti-cd28 and/or anti-b7h3 compositions
|
|
US11124568B1
(en)
*
|
2020-08-19 |
2021-09-21 |
Vitruviae LLC |
CD3/CD25 antibodies for neuro-immune diseases
|
|
JP7518286B2
(ja)
|
2020-08-25 |
2024-07-17 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hivを標的とする多重特異性抗原結合分子及び使用方法
|
|
WO2022087211A1
(en)
*
|
2020-10-22 |
2022-04-28 |
Janux Therapeutics, Inc. |
Antibodies targeting her2 and cd3 and uses thereof
|
|
AU2021374594B2
(en)
|
2020-11-04 |
2026-03-05 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies and anti-cd79b antibody drug conjugates
|
|
JP7716473B2
(ja)
|
2020-11-04 |
2025-07-31 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体の皮下投薬
|
|
TWI874719B
(zh)
|
2020-11-04 |
2025-03-01 |
美商建南德克公司 |
用抗cd20/抗cd3雙特異性抗體進行治療之給藥
|
|
WO2022148736A1
(en)
*
|
2021-01-05 |
2022-07-14 |
Transgene |
Vectorization of muc1 t cell engager
|
|
AU2022214319A1
(en)
|
2021-01-28 |
2023-08-03 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for treating cytokine release syndrome
|
|
US11739144B2
(en)
|
2021-03-09 |
2023-08-29 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and CLDN6
|
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
|
JP7714675B2
(ja)
*
|
2021-03-24 |
2025-07-29 |
ヤンセン バイオテツク,インコーポレーテツド |
CD79b、CD20、及びCD3を標的とする三重特異性抗体
|
|
CN114763387B
(zh)
*
|
2021-04-15 |
2024-06-25 |
北京大学深圳研究生院 |
一种基于结构优化蛋白活性的三特异性抗体制备方法
|
|
EP4337330A1
(en)
|
2021-05-14 |
2024-03-20 |
Genentech, Inc. |
Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
|
|
JP2024520444A
(ja)
|
2021-05-24 |
2024-05-24 |
プロヴェンション・バイオ・インコーポレイテッド |
1型糖尿病を治療するための方法
|
|
EP4380631A4
(en)
*
|
2021-08-04 |
2025-06-25 |
Abpro Corporation |
Cd3 targeting antibodies and uses thereof
|
|
US20250019455A1
(en)
*
|
2021-09-24 |
2025-01-16 |
Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
|
WO2023083381A1
(zh)
|
2021-11-15 |
2023-05-19 |
成都百利多特生物药业有限责任公司 |
双特异性抗体-喜树碱类药物偶联物及其医药用途
|
|
JP2025504795A
(ja)
*
|
2022-01-10 |
2025-02-19 |
ナンチン リーズ バイオラブス カンパニー,リミティド |
抗体及びその用途
|
|
EP4507790A1
(en)
|
2022-04-11 |
2025-02-19 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for universal tumor cell killing
|
|
KR20250035053A
(ko)
|
2022-06-07 |
2025-03-11 |
리제너론 파아마슈티컬스, 인크. |
T 세포 활성을 조절하기 위한 다중특이적 분자 및 이의 용도
|
|
WO2024071008A1
(ja)
*
|
2022-09-26 |
2024-04-04 |
愛知県 |
抗原分子の単離方法
|
|
WO2024088987A1
(en)
|
2022-10-26 |
2024-05-02 |
F. Hoffmann-La Roche Ag |
Combination therapy for the treatment of cancer
|
|
EP4640700A1
(en)
*
|
2022-12-19 |
2025-10-29 |
Harbour Biomed (Shanghai) Co., Ltd |
"kappa/lambda" fab-fab series-connection multi-specific binding protein, preparation thereof, and use thereof
|
|
CN120857940A
(zh)
|
2023-02-17 |
2025-10-28 |
瑞泽恩制药公司 |
对cd3/taa双特异性抗体有反应的诱导型nk细胞
|
|
WO2025085781A1
(en)
|
2023-10-19 |
2025-04-24 |
Genentech, Inc. |
Combinations of il15/il15r alpha heterodimeric fc-fusion proteins and her2xcd3 bispecific antibodies for the treatment of her2-positive cancers
|